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İbrahim Bozgeyik,Mehmet Şenel,Emre Çevik,M. Fatih Abasıyanık 한국물리학회 2011 Current Applied Physics Vol.11 No.4
An amperometric biosensor has been developed for the measurement of urea. To construct the proposed biosensor urease enzyme was immobilized onto poly(N-glycidylpyrrole-co-pyrrole) conducting film by direct covalent attachment. The biosensor surface was characterized by FTIR spectroscopy and atomic force microscopy (AFM). The response studies were carried out as a function of urea concentration with amperometric measurements. The biosensor showed a linear current response to the urea concentration ranging from 0.1 to 0.7 mM. The urea biosensor exhibited a sensitivity of 4.5 μA/mM with a response time of 4 s. The factors influencing on the performance of the resulting biosensor were also studied in detail.
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Zulkif Bozgeyik,Sait Berilgen,Huseyin Ozdemir,Aslan Tekatas,Erkin Ogur 대한영상의학회 2008 Korean Journal of Radiology Vol.9 No.6
Objective: To investigate the effects of sildenafil citrate (Viagra) on the vertebral artery blood flow of patients with vertebro-basilar insufficiency (VBI) using color duplex sonography (CDS). Materials and Methods: The study included 21 patients with VBI (aged 31-76; mean 61.0 ± 10.5 yrs). We administered a 50 mg oral dose of sildenafil citrate to all patients. Next, we measured the peak systolic velocity (Vmax), end diastolic velocity (Vmin), resistive index (RI), pulsatility index (PI), diameter, area, and flow volume (FV) of vertebral arteries using CDS before the administration of sildenafil citrate; 45 minutes after, and 75 minutes after administration. Statistical testing was performed using SPSS for windows version 11.0. The statistical test used to determine the outcome of the analysis was the repeated measures analysis of variance (ANOVA) test. Results: Compared to the baseline values, the vertebral artery diameter, area, and FV increased significantly following the administration of sildenafil citrate. The diameter, area and FV increased from 3.39 mm at 45 minutes to 3.64 mm at 75 minutes, 9.43 cm2 to 10.80 cm2 at 45 minutes and 10.81 cm2 at 75 minutes, as well as from 0.07 L/min at baseline to 0.09 L/min at 45 minutes and unchanged at 75 minutes, respectively. Conclusion: Sildenafil citrate elicited a significant effect on vertebral artery diameter, area and FVs. Objective: To investigate the effects of sildenafil citrate (Viagra) on the vertebral artery blood flow of patients with vertebro-basilar insufficiency (VBI) using color duplex sonography (CDS). Materials and Methods: The study included 21 patients with VBI (aged 31-76; mean 61.0 ± 10.5 yrs). We administered a 50 mg oral dose of sildenafil citrate to all patients. Next, we measured the peak systolic velocity (Vmax), end diastolic velocity (Vmin), resistive index (RI), pulsatility index (PI), diameter, area, and flow volume (FV) of vertebral arteries using CDS before the administration of sildenafil citrate; 45 minutes after, and 75 minutes after administration. Statistical testing was performed using SPSS for windows version 11.0. The statistical test used to determine the outcome of the analysis was the repeated measures analysis of variance (ANOVA) test. Results: Compared to the baseline values, the vertebral artery diameter, area, and FV increased significantly following the administration of sildenafil citrate. The diameter, area and FV increased from 3.39 mm at 45 minutes to 3.64 mm at 75 minutes, 9.43 cm2 to 10.80 cm2 at 45 minutes and 10.81 cm2 at 75 minutes, as well as from 0.07 L/min at baseline to 0.09 L/min at 45 minutes and unchanged at 75 minutes, respectively. Conclusion: Sildenafil citrate elicited a significant effect on vertebral artery diameter, area and FVs.
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Recurrent Retroperitoneal Cystic Lymphangioma
Huseyin Ozdemir,Ercan Kocakoc,Zulkif Bozgeyik,Bengu Cobanoglu 연세대학교의과대학 2005 Yonsei medical journal Vol.46 No.5
Retroperitoneal cystic lymphangioma is a rare congenital malformation. The majority of lymphangiomas are present at birth and nearly all present before the age of two years. We report a case of giant cystic retroperitoneal lymphangioma in a patient who first presented with symptoms at the age of 7, underwent surgery, and who then suffered a recurrent mass 11 years later.
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