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      • KCI등재후보

        만성 위염전 2 례

        박찬규,이동욱,남성진,김추성,조성래,구본천,박영재,허규찬 啓明大學校 醫科大學 1997 계명의대학술지 Vol.16 No.3

        위염전은 위의 비정상적인 회전으로 생기는데 급성증에서는 진단이 늦어질 경우 치명적일 수도 있으나, 만성증의 경우는 비특이적 위장관 중상을 나타내며, 치료되지 않을 경우 수년 동안 증상이 지속될 수도 있다. 최근 저자들은 소화불량, 식후 상복부 동통을 주소로 내원한 환자에서 만성위염전 2 례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Gastric volvulus is an abnormal rotation of the stomach. Gastric volvulus may present as an emergency or as a chronic condition. Acute volvulus si potentially lethal if unrecognized, while a chronic volvulus may cause symptoms for years if not treated. Gastric volvulus may be more common than previously estimated. Approximately 700 cases have thus far been documented. In patients with vague upper abdominal pain, bloating, vomiting, early satiety and weight loss, chronic gastric volvulus are reported and the related literature reviewed. The clinical presentation, diagnosis, and treatment are treatment are discussed. Features of acute and chronic volvulus are compared.

      • 후복막강내 발생한 Castleman병 1례

        남성진,이동욱,박찬규,정시욱,김추성,조성래,구본천,양사규,이일웅,박정자 慶北大學校 醫科大學 1997 慶北醫大誌 Vol.38 No.2

        Castleman' s disease is a rare, reactive lymphoid proliferation of unknown cause and pathogenesis. Depending on histololgic findings, it has been divided into two distinct histologic subtypes that include hyaline-vascular type(90%) and plasmacell type(10%). This disease occurs most commonly in mediastinal lymph nodes and cervical lymph nodes, inguinal lymph nodes respectively. But occurs rarely in retroperitoneum. We report a case of hyaline-vascular type asymptomatic Castleman' s disease of the retroperitoneum in a 47-year-old man.

      • KCI등재

        치경부 마모증 수복시 상아질 접착제가 변연누출에 미치는 영향

        손호현,구본욱 大韓齒科保存學會 1987 Restorative Dentistry & Endodontics Vol.12 No.2

        TRACT The purpose of this study is to evaluate the effect of dentin bonding agents on marginal leakage. V-shaped cavities were prepared on the faciocervical area of 140 extracted human teeth. In Groups of twenty cavities, they were restored as follow: Group 1 with enamel bonding resin and Silux, Group 2 Scotchbond and Silux, Group 3 enamel bonding resin and Heliomolar, Group 4 Dentin Adhesit and Heliomolar, Group 5 enamel bonding resin and Durafill, Group 6 Dentin Adhesive and Durafill, Group 7 Chembond. All specimens were thermocycled alternatively at 4? and 60? of 2% methylene blue dye solution, and sectioned faciolingually with diamond disk under water spray. The sectioned speci- mens observed with stereomicroscope.Following results were obtained: 1. The groups filled with Scotchbond-Silux or Dentin Adhesit-Heliomolar had appeared lesser marginal leakage compared with the groups with enamel bonding resin-Silux or enamel bond- ing resin-Helimolar. 2. The group filled with Dentin Adhesive-Durafill did not show the reduction of the marginal leakage compared with the group with enamel bonding resin-Durafill. 3. There was significant difference among the four dentin bonding agents. Scotchbond showed the greatest marginal sealing ability, and Dentin Adhesit was the next. The marginal sealing ability of Dentin Adhesive was the worst.

      • KCI등재후보

        인슐린 비의존성 당뇨병에 동반된 심상성 천포창 1 례

        이상준,박진용,임태형,윤영호,권순대,남창욱,허규찬,박근용,구본식,김상표,장종억 啓明大學校 醫科大學 1997 계명의대학술지 Vol.16 No.3

        저자들은 인슐린 비의존형 당뇨병 환자에서 통증성 구강내 미란 및 전신성 수포성 미란을 동반한 심상성 천포창 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Various skin conditions such as diabetic dermopathy, necrobiosis lipoidica diabeticorum, bullosis diabeticorum, granuloma annulare occur frequently in diabetes, although common lesions may be associated by chance. Pemphigus vulgaris(PV) is a blistering skin disease seen predominantly in elderly patients. This disorder is characterized by the loss of cohesion between epidermal cells with the resultant formation of intraepidermal blisters. These blisters rupture easily, leaving denuded areases that may crust and enlarge peripherally. In half or more of patients, lesions begin in the mouth: approximately 90% of patients have oromucosal involvement at some time during the course of their disease. But the relationship of this disorder with diabetes is not clear. We experienced a case of pemphigus vulgaris associated with NIDDM in 67 years old woman who was admitted due to painful oral ulcer and control of blood glucose, so we present this case with a review of literatures.

      • Performance Improvement of UWB-based Wireless Communication Systems

        Bon-Wook Koo,Jee-Hoon Kim,Hyoung-Kyu Song 대한전자공학회 2007 ITC-CSCC :International Technical Conference on Ci Vol.2007 No.7

        In this paper, we apply multiple antennas to MB-OFDM UWB system for high performance. With an emphasis on a preamble design for multi-channel separation, we address the channel estimation in MB-OFDM system with multiple antennas. By properly designing each preamble for multiple antennas to be orthogonal in time domain, the channel estimation can be applied to the MBOFDM proposal for IEEE 802.15.3a standard in the case of more than 2 transmit antennas.

      • SCOPUSKCI등재
      • KCI등재

        Effects of Tianeptine on The Activity of Glutamate Transporter EAAT3 Expressed in Xenopus Oocytes

        Bon-Wook Koo(구본욱),Hyo-Seok Na(나효석),Jung-Hee Ryu(유정희),Jung-Seok Choi(최정석),Sang-Hwan Do(도상환),Zhiyi Zuo(주오지이) 대한생물치료정신의학회 2020 생물치료정신의학 Vol.26 No.3

        배경:티아넵틴(tianeptine)은 최근 주목받고 있는 항우울제로 기존의 모노아민 항우울제(monoaminergic antidepressants)와 달리 케타민(ketamine)과 같이 글루타메이트(glutamate)의 신경전달에 영향을 미치는 것으로 알려져 있다. 글루탐산염 전달체, 특히 흥분성 아미노산 전달체 3형(Excitatory Amino Acid Transporter 3, EAAT3)에 대한 연구가 계속되어 왔지만 티아넵틴이 EAAT3에 미치는 영향에 대한 연구는 부족하다. 방법:개구리(Xenopus laevies) 난모세포에 EAAT3의 mRNA를 세포질내 주입하여 발현시킨 후, 2개의 전극을 이용한 전압클램프를 사용하여 L-glutamate 투여 전, 중, 후로 막전위를 측정하였다. 반응값은 막전위의 변화를 적분하여 구하였으며, microcoulomb 단위로 제시하였다. 데이터는 평균 ± 표준오차로 표기하였다. 결과:티아넵틴은 EAAT3의 활성도를 농도의존적으로(0.1~100μM) 감소시켰으며 1mM 티아넵틴을 72시간 동안 노출 시켰을 때 Km(27.0±7.6 vs. 23.3±4.9mM, n=84, p=0.72)의 변화없이 Vmax(6.9±0.6 vs. 4.8±0.3mC, n=84, p<0.05)를 유의미하게 줄였다. 결론:개구리 난모세포에 티아넵틴을 72시간 동안 노출시켰을 때 농도의존적으로(1~100mM) EAAT3의 활성도를 감소시켰다. 이번 연구의 결과는 티아넵틴이 EAAT3의 이용 가능한 수나 회전률을 감소시킴으로써 활성도를 감소시키는 것을 시사한다. Objectives : Tianeptine is an antidepressant that has drawn attention recently. Unlike traditional monoaminergic antidepressants, tianeptine is known to affect glutamate neurotransmission like ketamine. However, there has been paucity of studies investigating the role of tianeptine on glutamate transporters, especially excitatory amino acid transporter type 3 (EAAT3). Methods : After expression of EAAT3 by intracellular injection of EAAT3 mRNA, we investigated the effect of tianeptine on the activity of EAAT3, by measuring membrane current in response to L-glutamate administration using Xenopus oocyte expression system and two-electrode voltage clamps. Results : Tianeptine (1mM for 72h) significantly reduced Vmax (6.9±0.6 vs. 4.8±0.3mC, n=14-22, p<0.05) without changing Km (27.0±7.6 vs. 23.3±4.9mM, n=14-22, p=0.72). Conclusion : When tianeptine was exposed for 72h, it decreased the activity of EAAT3 in a concentration-dependent manner (1-100mM). Our results suggest that tianeptine decreases EAAT3 activity by reducing the available number or turnover rate of EAAT3.

      • KCI등재

        Comparison of Postural Control Ability according to the Various Video Contents during Action Observations

        ( Bon Wook Goo ),( Mi Young Lee ) 대한물리치료학회 2021 대한물리치료학회지 Vol.33 No.1

        Purpose: This study examined the effects of the type of video contents used for action observations on the ability to control posture. Methods: The participants were 48 healthy adults. The two hands of the participants were crossed on both shoulders, and the other foot was placed in a straight line in front of the target to allow them to watch a video of the monitor. The videos were presented in random order with three video contents (natural, stable balance posture, and unstable balance posture) consisting of 30 seconds each. A 15-second resting time was given between each video. During action observation using various video content forms, the posture control ability was measured using a TekScan MetScan® system. Results: The results revealed statistically significant differences in the area of movement and the distance by COP and distance by the type of action-observation videos, and the distance by the anteroposterior and mediolateral sides (p<0.05). The stable balance posture and unstable balance posture video showed significant differences in the distance by the COP, anteroposterior, and mediolateral distance. (p<0.05) Conclusion: This study suggests that choosing the contents of the videos is important during action-observation training, and action-observation training can help improve postural control.

      • SCISCIESCOPUS

        High-speed MB-OFDM system with multiple antennas for multimedia communication and home network

        Bon-Wook Koo,Myung-Sun Baek,Young-Hwan You,Hyoung-Kyu Song IEEE 2006 IEEE transactions on consumer electronics Vol.52 No.3

        <P>The rapid dissemination of digital consumer electronics devices within home and personal area causes increments of multimedia communication and of home networking. In order to meet the demand for low cost, high performance wireless entertainment network, multiple transmitting and receiving antennas can be used in MB-OFDM system to attain high-rate transmission and to offer better quality of service. The MB-OFDM system with multiple antennas increases the transmission rate efficiently with low multiplication operations. With an emphasis on a preamble design for multi-channel separation, we address a channel estimation in MB-OFDM with MIMO antenna system. By properly designing each preamble for multiple antennas to be orthogonal in time domain, the channel estimation can be applied to the MB-OFDM proposal for IEEE 802.15.3a standard in the case of more than two transmitting antennas</P>

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