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      • 대학생의 수면양상과 수면장애요인에 관한 연구

        김유진,박미경,박이랑,이보람,이혜림,전선미,양난영,김수지,이자형 이화여자대학교 간호과학대학 2004 이화간호학회지 Vol.- No.38

        The results of this Study are as follows:33.6% of all participants have insomnia; 22.5% of those who have insomnia are DIS(difficulty in initiating sleep), 17.3% are DMS(difficulty returning to sleep once awakened) and 7.0% awakened too early. 3 4.8% experience sleepiness during daytime. Type 1, experiencing insomnia and sleepi ness during daytime together, is 12.0%, Type 2, with insomnia only, is 21.6%, Type 3, with sleepiness during daytime only, is 22.8% and 43.5% experience no sleeping disturbances. After studying only those with 3 types of sleeping disturbances, it is found that the most common cause of such disturbance is stress 88.4%, anxiety 56.0%, no apparent reason 33.8%, anxiety/fear/terror 29.3%, hurry 23.6%, alcohol/caffeine 16.9%, bedroom tem perature 11.1%, urination during nighttime and persons living together 10.7%, noise from inside 8.9%, illumination 8.0%, and pain/itch 5.8%. The one group revealed significant differences in residential environment(p=0.003). Sex, age, education level, medicine, monthly earning revealed no meaningful differences. Of sleeping behavior, mean duration of sleep latency(p=0.000), whether or not feeling freshness(p=0.000), whether taking enough sleep(p=0.029), whether taking regular sleep(p=0.005) showed significant differences depending on whether or not having insomnia, and mean duration of sleep time, time to sleep, time of rising, whether taking naps did not reveal significant differences. Of sleep behavior, time to sleep(p=0.000), whether taking naps(p=0.000), indicated significant differences. Of sleeping behavior, mean duration of sleep latency(p=0.000), whether or not feeling freshness(p=0.000), and whether taking enough sleep(p=0.000), time of going to bed (p=0.002), whether or not taking nap(p=0.000), whether or not taking regular sleep(p=0.010) indicated significant differences among the sleeping disturbance types.

      • 관상동맥 질환에서 SDF-1α의 농도

        김보영,박용규,박형서,노상필,정승현,이유선,이정우,이재환,최시완,정진옥,성인환 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

        Atherosclerosis is now viewed as an inflammatory disease of the vascular system. Expression of several chemokines, including monocyte chemoattractant protein(MCP)-1, MCP-4, RANTES(regulated on activation normal T-cell expressed and secreted), and interleukin-8(IL-8) are increased in human atherosclerotic plaques compared with normal vessels. They are involved in the pathogenesis of atherosclerosis and plaque rupture by activating and directing leukocytes into the atherosclerotic lesions. However, some are involved in homeostatic functions such as normal leukocyte traffic and growth regulation. SDF-la is a multi-functional cytokine that is involved in myelogenesis, hematopoiesis, angiogenesis and injured gastric mucosal regeneration in the gastric ulcer patient. SDF-la is recently shown to be highly expressed in atherosclerotic plaques and a potent platelet agonist. At least in high concentrations, SDF-la may mediate antiinflammatory and matrix stabilizing effects in unstable angina. Many studies are going on to know the function of SDF-la in coronary artery diseases. I investigated the difference of the plasma level of SDF-la between control group and coronary artery disease group. Total 75 subjects were enrolled. The diagnosis of coronary artery disease was confirmed in all patients by coronary angiography. Control subjects in this study were confirmed normal by coronary angiography. Clinical profile and risk factors were also reviewed. Control subjects in this study were 27 (M=10, F=17). Plasma for the study was collected before the angiography and centrifuged. SDF-la analysis was performed by ELISA. Plasma level of SDF-la is significantly increased in patients with stable angina(n=20) and unstable angina group(n=28) compared with healthy control group(n=27). the risk factors do not influence the plasma level of SDF-la in coronary artery diseases. In this study, plasma level of SDF-la is increased in patients with stable angina and unstable angina groups compared with healthy control group(P<0.05). the risk factors do not influence the plasma level of SDF-la in coronary artery diseases.

      • 한의약 컨텐츠를 가미한 강원도 리조트형 웰니스 프로그램 제안

        유준상, 권보인, 이재형 상지대학교 한의학연구소 2023 尙志韓醫論文集 Vol.11 No.1

        Objectives: As interest in wellness tourism is increasing in Korea, we sought to propose a program with Korean Medicine Contents for eight resorts in Gangwon-do, which has forests and marine resources. Methods: The authors visited eight designated resorts in Gangwon-do, observed the facilities, and interviewed the people in charge. Questions and answers were asked and answered in the form of a questionnaire regarding any deficiencies in the interviews. Afterwards, the contents were analyzed and a Korean Medicine program suitable for each resort was proposed. Results: A total of 17 Korean Medicine Programs were proposed, of which the meditation/yoga program and diet/drink program tailored to each constitution were proposed to be applicable to all 8 resorts. The rest were proposed considering each resort's facilities, environmental characteristics, and main product programs. Conclusions: It appears that the ‘meditation/yoga program’ and ‘constitutional diet and beverage development’ sectors are programs that can be commonly carried out by all facility companies, and for this purpose, the Sasang constitution test and Korean medicine measurement within the resort in Gangwon-do are used to create a program linked to this. In addition, we believe that efforts to improve the program through verification of efficacy will be necessary in the future

      • 대학생의 취업스트레스와 자아존중감, 자아효능감, 외모관리행동의 관계

        김보라,김유진,김지희,노혜진,오승희,홍지혜,황윤희,박선아 水原大學校 2016 論文集 Vol.30 No.-

        Purpose: Many university students are under a lot of job-seeking stress because the employment rate is low. This study sought to determine the relationship between job-seeking stress, self esteem, self efficacy and appearance management behavior amongst university students focusing on nursing. Methods: This descriptive correlational study evaluated the relationships between job-seeking stress, self esteem, self efficacy and appearance management behavior of 340 university students was conducted between September 1 and October 5, 2015. Results: The correlational analysis between job-seeking stress, self esteem, self efficacy and appearance management behavior revealed a negative correlation between job-seeking stress, self esteem and self efficacy and a positive correlation between job-seeking stress and appearance management behavior. In addition, age also correlated with self esteem, self efficacy and appearance management behavior. Conclusion: Stress correlated with self esteem and self efficacy and appearance management behavior. Therefore job-seeking stress may be reduced through not only self esteem and self efficacy enhancement programs but also management according to age.

      • 벼꽃으로부터 두 개의 calmodulin cDNA 유전자의 분리 및 특성 연구

        고보경,고명수,김유정,정일선,최영주 신라대학교 자연과학연구소 2005 自然科學論文集 Vol.14 No.-

        Ca^(2+)은 신호전달과정에서 중요한 작용을 하는데 CaM은 이러한 Ca^(2+)이은의 modulator로서 중요한 작용을 하는 것으로 알러져 있다. 벼꽃의 cDNA library로부터 rice genomic DNA(RCaM-2)를 probe로 사용하여 30여개의 Positive clones을 얻어 이 중 두 개의 벼꽃 calmodulin CDNA clone을 분리하였다. RFCaMs CDNA clone의 총염기수는 RFCaM-3은 831p, RFCaM-4는 751bp이고 open reading frame은 각각 149개의 아미노산으로 구성되어 있다. RFCaM-3 과 RFCaM-4의아미노산은 동일하지만 nucleotide 순서는 상당한 차이를 나타내고 있다. RFCaMs CDNA clone의 open reading flame은 protein serine/threonine kinase에 보존되어 있는 catalytic domain을 가지고 있다 RfCaM-3은 5'-untranslated region은 105bp, 3'-untranslated region은 270bp이고 RfCaM-4는 5'-untranslated region은 78bp, 3'-untranslatedregion은 283bp이다. RFCaMs는 Arabidopsis와 70%, potato와는 92%, carrot과는 98%의 유사성을 보였다. Genomic southern blot분석에 의하면 벼의 clamodulin 유전자들이 7-8개의 multigene family로 존재하는 것으로 나타났다. Two different calmodulin (CaM) cDNAs (RFCaM-3 and RFCaM-4) were isolated from a rice flower cDNA library by screening with a rice genomic probe (RCaM-2). Both cDNAs are 90% sequence homologous inside the coding region but are highly divergent outside this region. The polypeptides encoded by RFCaM-3 and RFCaM-4 show identical sequence homology. Comparison of the deduced amino acid sequence of the RFCaMs cDNA clone have identity to Arabidopsis (70%), potato (92%), carrot (98%), and barley and soybean (98%). Southern analysis revealed that both cDNAs are encoded by different genes. Four intense and a few weaker bands were observed in the restriction fragments. Most restriction fragments showed high intensity hybridization signals under stringent conditions, suggesting the presence of a small multigene family for CaM in the rice genome as in other plants.

      • Papain 유도 호흡기 염증모델에서 인삼패독산(人蔘敗毒散)의 항염증 효과

        우연주, 유준상, 이동혁, 서진우, 김주희, 권보인 상지대학교 한의학연구소 2023 尙志韓醫論文集 Vol.11 No.1

        Objectives: Insampaedok-san and its main components have been used for treatment of fever, joint pain, cough, headache and pain. Using a respiratory inflammation model, we intend to investigate the anti-inflammatory effect and its mechanism of Insampaedok-san. Methods: We induced the actue respiratory inflammatory mouse model by papain treatment. BALB/C mice (female, 8 weeks old) were divided into three groups as follows: saline control (SC): papain treated group (vehicle): papain and Insampaedok-san (200mg/kg) treated group (n=4). To demonstrate the ani-inflammatory effect of Insampaedok-san water extracts, inflammatory cell infiltration was evaluated in bronchoalveolar lavage fluid (BALF) and nasal lavage fluid (NALF). In addition, immunogloblin (Ig)-E level was measured by using ELISA. Results: Insampaedok-san extracts administration decreased inflammatory cell infiltration in BALF and NALF. Especially, eosinophil infiltration was dramatically reduced. Furthermore, total Ig-E level was diminished in BALF and serum by Insampaedok-san administration. Conclusions: Our findings revealed Insampaedok-san extracts have anti-inflammatory effects by inhibiting inflammatory cell, especially eosinophil infiltration and Ig-E level.

      • 대학생의 식행동과 식사의 질에 대한 연구

        김은미,이보경,장유경 漢陽大學校 韓國生活科學硏究所 1999 韓國 生活 科學 硏究 Vol.- No.17

        This study was performed to assess the diet-related behavior and food quality of 164 college students. Survey questionnaires including 24-hr dietary recall, diet-related behavior and anthropometric measurements were applied as the instruments. The results obtained were as follows. Body fat of female college students was higher than that of male college students and body fat of family history group was higher than that of non-family history group. By the value of BMI(body mass index), 62.5% of female college students were underweight and 52.6% of male college students were normal weight. WHR(Waist/ Hip ratio) of male and female college students was 0.79±0.01 and 0.71±0.01, respectively. Dietary behavior score was not significantly different between male and female college students, and between family history group and non-family history group. But family history group was concerned dietary behavior. The overall diet quality was assessed by RDA(Recommendation dietary allowance) for Korea, MAR(Mean adequacy ratio) and INQ(Index of nutritional quality). Intakes of P, vitamin B1, vitamin C, in students were more than RDA and intakes of energy, Ca, vitamin B2, niacin in students were below RDA. NAR was less than RDA and Ca was one of the seriously deficient nutrients in students. MRA was significantly different between male(0.80) and female college students(0.74), and the overall diet quality was low, especially among female college students. INQs of vitamin B2, niacin intake were low in male college students and INQs of Fe, vitamin A were low in female college students. There were positive correlation between the number of meals per day, nutrient intake and MAR. Therefore, nutrition education for college students is necessary, and new menus of campus cafeteria should be developed to meet the various needs of students.

      • 다결정 니켈표면과 산소 기체와의 상호 작용

        안운선,이순보,부진효,박유용 성균관대학교 기초과학연구소 1986 論文集 Vol.37 No.2

        The interaction of the gaseous oxygen molecule with polycrystalline nickel surface has been studied by the XPS through the wide range above the room temperature. For relatively lower oxygen exposure, only an O(1s) peak was observed at 530.2 eV, which is associated with the dissociative adsorption. On the other hand, with increasing oxygen exposures, two peaks was appeared at 529.7eV and 531.3eV. These peaks are attributed to nickel oxide and Ni_2O_3, respectively. The latter oxide is ascribed due to the excess adsorption over the NiO stoichiometry. However at high temperatures above 423K, the dissociative adsorption and oxidation was found to take place simultaneously. As a whole, through these XPS study it is found that the interaction of the oxygen with the polycrystalline nickel surface commences through three steps: the fast dissociative adsorption following slow initiation process, rapid oxidation corresponding to the epitaxial NiO formation, and finally the bulk oxide formation.

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