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( Bernardino Roca ),( Raquel Monferrer ),( Jose A Ferrero ),( Manuel Roca ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Objective: To find factors associated with increased homocysteine serum level in HIV-infected patients. Methods: Cross-sectional study, carried out as a supplementary task to the usual follow- up of HIV-infected patients. The possible association of increased homocysteine serum level with blood analyses results was assessed with a multiple linear regression analysis. Results: A total of 145 patients were included. Creatinine was higher than normal in 7 patients (5 %), prothrombin time was higher than normal in 36 patients (25 %), and a monoclonal gammopathy was detected in 2 patients (1 %). An association was found between high homocysteine serum level and the following variables: high creatinine (P < 0.001), low folic acid (P < 0.001), and low prothrombin time (P = 0.007). Conclusion: An associations was found between high homocysteine serum level and low prothrombin time.
Luca Landi,Bernardino Pollio,Pier Paolo Diotallevi 국제구조공학회 2014 Structural Engineering and Mechanics, An Int'l Jou Vol.51 No.3
The purpose of the research presented in this paper was to investigate the effectiveness of several conventional, multi-modal and adaptive pushover procedures. In particular, an extensive numerical study was performed considering eight RC frames characterized by a variable number of storeys and different properties in terms of regularity in elevation. The results of pushover analyses were compared with those of nonlinear dynamic analyses, which were carried out considering different earthquake records andincreasing values of earthquake intensity. The study was performed with reference to base shear-top displacement curves and to different storey response parameters. The obtained results allowed a direct comparison between the pushover procedures, which in general were able to give a fairly good estimate of seismic demand with a tendency to better results for lower frames. The advanced procedures, in particular the multi-modal pushover, provided an improvement of the results, more evident for the irregular frames.
Landi, Luca,Pollioa, Bernardino,Diotallevi, Pier Paolo Techno-Press 2014 Structural Engineering and Mechanics, An Int'l Jou Vol.51 No.3
The purpose of the research presented in this paper was to investigate the effectiveness of several conventional, multi-modal and adaptive pushover procedures. In particular, an extensive numerical study was performed considering eight RC frames characterized by a variable number of storeys and different properties in terms of regularity in elevation. The results of pushover analyses were compared with those of nonlinear dynamic analyses, which were carried out considering different earthquake records and increasing values of earthquake intensity. The study was performed with reference to base shear-top displacement curves and to different storey response parameters. The obtained results allowed a direct comparison between the pushover procedures, which in general were able to give a fairly good estimate of seismic demand with a tendency to better results for lower frames. The advanced procedures, in particular the multi-modal pushover, provided an improvement of the results, more evident for the irregular frames.
Minimum reinforcement and ductility index of lightly reinforced concrete beams
Alessandro P. Fantilli,Bernardino Chiaia,Andrea Gorino 사단법인 한국계산역학회 2016 Computers and Concrete, An International Journal Vol.18 No.6
Nonlinear models, capable of taking into account all the phenomena involved in the cracking and in the failure of lightly reinforced concrete beams, are nowadays available for a rigorous calculation of the minimum reinforcement. To simplify the current approaches, a new procedure is proposed in this paper. Specifically, the ductility index, which is lower than zero for under-reinforced concrete beams in bending, is introduced. The results of a general model, as well as the data measured in several tests, reveal the existence of two linear relationships between ductility index, crack width, and the amount of steel reinforcement. The above relationships can be applied to a wide range of lightly reinforced concrete beams, regardless of the geometrical dimensions and of the mechanical properties of materials. Accordingly, if only a few tests are combined with this linear relationships, a new design-by-testing procedure can be used to calculate the minimum reinforcement, which guarantees both the control of cracking in service and the ductility at failure.
Park, Cheol Min,Bernardino, Michael E. 고려대학교 의과대학 1994 고려대 의대 잡지 Vol.31 No.2
골수이식수술후 간비장에 발생하는 미세농양의 방사선학적 빈도와 원인균(세균성, 진균성)의 감별을 알아보기 위하여 최근 4년 3개월동안 골수이식수술을 받은 241명중 CT(n=145)와 MR(n=17)을 시행하였던 145명 환자의 방사선학적소견과 의무기록을 후향적으로 분석하여서 6명의 간비장미세농양을 확인하였고 CT에서 6예(4.1%), MR(n=17)을 시행하였던 145명 환자의 방사선학적소견과 의무기록을 후향적으로 분석하여서 6명의 간비장미세농양을 확인하였고 CT에서 6예(4.1%), MR에서 2예(11.8%)가 발견되었다. 한편, 골수이식수술의 과거력이 없이 간비장미세농양이 발생한 8예와 합한 총 14예에서 CT이나 MR사진중 병변이 가장 많이보인 절편에서 병변의 숫자를 원인균과 비교한 결과, 10개 이상의 병변이 관찰되었던 10예중 9예가 진균성 원인으로 증명되었다. 진균성 병변들은 장기안에 흩어진 소견을 보인반면, 비장의 화농성 미세농양 2예는 병변이 10개 미만이면서 서로 합하려는 소견을 보였다. 골수이식수술후 간비장미세농양에 대한 CT발견율은 4.1%, MR발견율은 11.8%이었다. 병변이 가장 많이 보이는 CT나 MR절편에서 10개이상이면 진균성을, 병변이 사로 합하려는 경향이면 세균성을 암시하는 소견으로 감결진단에 도움이 될 것으로 사료된다.
Lizbeth Anahı´ Portillo-Torres,Aurea Bernardino-Nicanor,Jose´ Mercado-Monroy,Carlos Alberto Go´mez-Aldapa,Leopoldo Gonza´lez-Cruz,Esmeralda Rangel-Vargas,Javier Castro-Rosas 한국식품영양과학회 2022 Journal of medicinal food Vol.25 No.9
To determinate the antimicrobial effect of chloramphenicol and aqueous extract against multidrug-resistant enterohemorrhagic Escherichia coli (EHEC) and Salmonella enterica serovar Typhimurium in CD-1 mice. Aqueous extract was isolated from Hibiscus sabdariffa calyces. The minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) of chloramphenicol and aqueous extract were determined for EHEC and S. Typhimurium. Nine groups of six mice each were formed. Three groups were inoculated orally with 1 × 104 colony-forming units (CFU) of S. Typhimurium, three groups were inoculated with 1 × 104 CFU of EHEC and the remaining three groups were not inoculated. Six hours postinoculation, the mice of some groups were orally administered solutions of aqueous extract (50 mg/mL), chloramphenicol (82 μg/mL), or isotonic saline. The EHEC and S. Typhimurium concentration in all mice feces was determined. For both pathogens, the MIC and MBC values of aqueous extract were 20 y 50 mg/mL, respectively; for chloramphenicol, they were between 17.5 and 82 μg/mL. EHEC and S. Typhimurium were not detected in the feces of mice that were administered aqueous extract on the 2nd and 3rd days posttreatment. Furthermore, these mice recovered from the infection. In contrast, in mice not treated, or treated with chloramphenicol alone, pathogens were isolated from their feces throughout the study, and some mice died. The H. sabdariffa calyx extracts could be an alternative to control multidrug-resistant bacteria in humans and animals.
Nonlinear Observer-based Active Control of Ground Vehicles with Non Negligible Roll Dynamics
Riccardo Cespi,Cuauhtemoc Acosta Lua,Bernardino Castillo-Toledo,Stefano Di Gennaro 제어·로봇·시스템학회 2016 International Journal of Control, Automation, and Vol.14 No.3
In this paper we present an observer–based nonlinear controller for lateral and yaw velocity, for a vehiclein which the roll dynamics can not be neglected. The observer estimates the lateral velocity, and the roll positionand velocity. This technique is based on measurements of the longitudinal and lateral accelerations, longitudinalvelocity, yaw rate and steer angle, usually available in modern vehicles. The nonlinear observer ensures exponentialconvergence of the estimations. The test maneuvers, obtained with the full–vehicle CarSim model under differentroad adhesion conditions, have been used to check the controller performance, as well as its robustness with respectto parameter variations.
Castiblanco Diana Maryuri Correa,Lima Michele Bernardino de,Artoni Silvana Martinez Baraldi,Raimundo Erikson Kadoshe de Morais,Santos Daniel Silva,Carvalho Lizia Cordeiro de,Silva Edney Pereira da 아세아·태평양축산학회 2023 Animal Bioscience Vol.36 No.1
Objective: Current quail production is configured as an economic activity in scale. Advancements in quail nutrition have been limited to areas such as breeding and, automation of facilities and ambience. The objective of this study was to evaluate the performance responses, liver and oviduct morphometry, and liver histology of Japanese laying quails subjected to different levels of nitrogen-corrected apparent metabolizable energy (MEn). Methods: A completely random design was used that consisted of nine levels of MEn, six replicates, and five hens per cage with a total of 270 quails. The experimental period lasted for 10 weeks. The variables of performance were subjected to analysis of variance and then regression analysis using the broken-line model. The morphometric and histological variables were subjected to multivariate exploratory techniques. Results: The MEn levels influenced the responses to zootechnical performance. The brokenline model estimated the maximum responses for feed intake, egg production, egg weight, and egg mass as 3,040, 2,820, 1,802, and 2,960 kcal of MEn per kg of diet, respectively. Multivariate analysis revealed that the occurrence of hepatic steatosis and increased levels of Kupffer cells were not related to MEn levels. Conclusion: The level of 2,960 kcal/kg of MEn meets performance variable requirements without compromising hepatic physiology.
Structural robustness of RC frame buildings under threat-independent damage scenarios
Antonio Ventura,Valerio De Biagi,Bernardino Chiaia 국제구조공학회 2018 Structural Engineering and Mechanics, An Int'l Jou Vol.65 No.6
This study focuses on a novel procedure for the robustness assessment of reinforced concrete (RC) framed structures under threat-independent damage scenarios. The procedure is derived from coupled dynamic and non-linear static analyses. Two robustness indicators are defined and the method is applied to two RC frame buildings. The first building was designed for gravity load and earthquake resistance in accordance with Eurocode 8. The second was designed according to the tie force (TF) method, one of the design quantitative procedures for enhancing resistance to progressive collapse. In addition, in order to demonstrate the suitability and applicability of the TF method, the structural robustness and resistance to progressive collapse of the two designs is compared.
Structural robustness of RC frame buildings under threat-independent damage scenarios
Ventura, Antonio,De Biagi, Valerio,Chiaia, Bernardino Techno-Press 2018 Structural Engineering and Mechanics, An Int'l Jou Vol.65 No.6
This study focuses on a novel procedure for the robustness assessment of reinforced concrete (RC) framed structures under threat-independent damage scenarios. The procedure is derived from coupled dynamic and non-linear static analyses. Two robustness indicators are defined and the method is applied to two RC frame buildings. The first building was designed for gravity load and earthquake resistance in accordance with Eurocode 8. The second was designed according to the tie force (TF) method, one of the design quantitative procedures for enhancing resistance to progressive collapse. In addition, in order to demonstrate the suitability and applicability of the TF method, the structural robustness and resistance to progressive collapse of the two designs is compared.