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      • SCOPUSKCI등재

        Lipids and Apolipoproteins in Insulin-dependent Diabetes During Long-term Intensified Insulin Treatment

        Jirkovska´, A.,Drya´kova´, M.,Poledne, R.,Skibova´, J.,Va´lek, J.,Bartosˇ, V.,Filip, K. 대한내분비학회 1992 Endocrinology and metabolism Vol.7 No.2

        The aim of the study, conducted in insulin-dependent (ID) diabetics for a period of 12±7 months, was to assess the effect of diabetic control and daily insulin dose during long-term intensified insulin treatment (ⅡT) on serum lipids and apolipoproteins. Out of the twenty seven ID diabetics, free of clinical manifestations of coronary heart disease and with normal renal function, ten were treated with continuous subcutaneous insulin infusion (CSⅡ), six with multiple dose regimen, and eleven with a basal-bolus regimen. All types of ⅡT led to good diabetes compensation and there was no difference among them in lipoprotein parameters nor in used daily doses of insulin. The glucose control (Michaelis) index correlated statistcally significantly with total cholestetol (chol) and apolipoprotein B (ApoB), both at the level of p$lt;0.01, with triglycerides (TG) and with the atherogenic index (ApoB/ApoAl)(both p$lt;0.05). The daily dose of insulin, related to 1kg of weight, correlated with Chol, TG, ApoB, LDL-cholesteroloB/ApoAl and with the atherogenic index of cholesterol (all at the level of significance p$lt;0.01). Hyperlipoproteinaemia was diagnosed in three patients. Despite the low incidence of hyperlipopreteinaemias in the group, our results indicate associations between lipids and apolipoproteins, and both the degree of diabetes compensation and the dose of exogenous insulin during ⅡT. To prevent development of macroangiopathy in ID diabetics, it is therefore necessary to achieve good compensation with as low doses of insulin as possible. (J Kor Soc Endocrinol 7:143~148, 1992)

      • Poster Session : PS 0114 ; Cardiology : Syncope -A Retrospective Study in an Emergency Hospital

        ( Daniela Bartos ),( Alina Ripa ),( Claudia Negrea ),( Mihaela Hostiuc ),( Cristina Tirziu ),( Florentina Mehic ),( Elisabeta Badila ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Syncope is a commonly encountered problem in an emergency hospital. Global cerebral hypoperfusion is the fi nal pathway common to all presentations of syncope, but this symptom presentation has a broad differential diagnosis. It is important to identify patients whose syncope is a symptom of a potentially life-threatening condition. Methods: Adult patients with syncope presenting to the Emergency Hospital from January 2012 to June 2014 were identifi ed. Diagnosis was established retrospectively by reviewing medical records. Results: Of 590 patients found in our hospital`s database we selected 218 patients who met our criteria. The demographics of our group show a slightly different distribution of the incidence between men and women (49% men and 51% women) and a majority of incidence in the urban medium (67%). As for the age range, most of our patients were >80 years old (28%), 22% were in the range of 70-80 years and the percentage decreases signifi cantly in the 60-70 years range (15%). The most frequent causes of syncope were cardiac (32%), vasovagal (23%) and due to orthostatic hypotension (12%), but we have also found various cases of mixt or iatrogenic causes. Conclusions: The incidence of syncope increases sharply after 70 years of age and poses special consideration in light of multiple comorbid conditions, age-related changes, atypical presentation, and concomitant medication use. The most common causes of syncope in this population are cardiac causes, orthostatic hypotension and carotid sinus hypersensitivity. Often, patients remain undiagnosed, despite exhaustive diagnostic testing.

      • Slide Session : OS-GAS-07 ; Gastroenterology : Drug Induced Idiosyncratic Hepatic and Pancreatic Tox-icity

        ( Daniela Bartos ),( Madalina Ilie ),( Camelia Diaconu ),( Gabriel Constantinescu ),( Amalia Vatuiu ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Even if Acetaminophen causes in the majority of cases dose dependent hepatotoxicity, idiosyncratic reactions represent a major diagnosis challenge for the clinician. Methods: We present the case of a 53 years old male that is sent to our hospital with jaundice, fatigue and fever. One month ago he was admitted in the local hospital for fever and he received for ten days, cephalosporins and 1 g/day Acetaminophen. After 5 days from finishing this therapy he developed jaundice with total bilirubin of 24 mg/ dl and ALT of 2300 U/l. Viral hepatitis markers were negative and abdominal CT scan was normal. They have also performed a cranial CT scan that showed osteocondesation lesions in the skull. Despite the normal findings on the abdominal CT scan, the patient is sent to our hospital with the suspicion of cholangiocarcinoma with skull metastasis in order to perform ERCP. Results: At the admission in our hospital we have repeated an abdominal ultrasound that revealed normal bile main duct, no dilation of intrahepatic ducts. We have also tested him for Leptospirosis that came out negative and the haematologist excluded the possibility of a myeloma. On the fourth day the repeated abdominal ultrasound and lipase values con. rmed acute pancreatitis and lymphadenopathy in the spleen hilum, but the patient had no pain. One month from presentation, the patient has normal bilirubin. Conclusions: Idiosyncratic Acetaminophen reactions are very rare, have a latent period and include systemic features: fever, hepatotoxicity, acute pancreatitis and lymphadenopathy. A high clinical suspicion based on the drug history and on the normal abdominal imaging represents the key of the diagnosis. Symptoms remission after stopping the offending drug, confirms the diagnosis.

      • SCOPUSKCI등재
      • KCI등재

        Hydrophobization of cotton fabric by Gliding Arc plasma discharge

        Pavel Cerny,Petr Bartos,Pavel Olsan,Petr Spatenka 한국물리학회 2019 Current Applied Physics Vol.19 No.2

        The surface modification in order to obtain hydrophobic cotton fabrics was carried out using air/HMDSO Gliding Arc plasma discharge. The dependence of the surface wettability on used process parameters, such as air flow, sample distance and treatment time were investigated. The wettability of cotton fabrics was evaluated by the drop test method by measuring the time of droplet absorption and water contact angle (WCA). The changes in the surface morphology were examined by optical microscopy and scanning electron microscopy (SEM). The treated hydrophobic fabrics were subjected to the analysis of chemical composition of the applied coatings using the ATR-FTIR spectroscopy. Hydrophobic cotton fabrics were obtained, especially with a high resistance to static wetting. In addition, the treated cotton fabrics were tested using a spray test measurement and were subjected to multiple washing.

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