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방은옥,정용준,조영채 忠南大學校 環境問題硏究所 2002 環境硏究 Vol.20 No.-
This study was conducted to investigate the concentration of the heavy metals among the soils and crops, and the difference compared with the unpolluted area from the radius distance from the ruined mine. Gubong Mind in Cheongyang-Gun, Chungnam-Do was selected as the ruined mine, which the Taechi-Myon district was selected ad the unpolluted control area. Pepper, welch onion, cabbage, radish and their soils were collected at the mine and unpolluted area, respectively. The concentration of heavy metals(Pb, Cd, Cu, Zn and As) were measured by ICP. In the soil sample, the average concentrations of all the heavy metals were significantly increased in the min area compared with those of the unpolluted area and significantly differed from the radius distance from ruined mine. In the crop sample, the average concentration of Pb, Zn and As metals were significantly increased in the mine area compared with those of the unpolluted area and all the heavy metals were significantly differed from the radius distance from ruined mine. There was a significant negative correlation among the soils from the radius distance from ruined mine and among the crops in the concentrations of all the heavy metals. There was a significant positive correlation between soils and crops in concentration of Pb, Cd, Zn and As metals. The results indicate the concentrations of heavy metals among the soils and crops at the ruined mine were saturated more than the unpolluted and the soil metals had spread to the crops. Consequently, we cannot leave the matter unsettled and its utilization must be studied to lower the contamination degree.
장벽 에너지 근처에서의 중이온 산란, 직접 반응과 융합의 준 고전적 특성과 광혹 모델 기술
이채호 ; 박수봉 ; 이상덕 ; 소운영 김천대학교 2003 김천대학교 논문집 Vol.24 No.-
An approach is proposed to calculate the direct reaction (DR) and fusion probabilities for heavy ion collisions at near-Coulomb-barrier energies as functions of the distance of closest approach D within the framework of the optical model that introduces two types of imaginary potentials, DR and fusion. The probabilities are calculated by using par- tial DR and fusion cross sections, together with the classical relations associated with the Coulomb trajectory. Such an approach makes it pos- sible to analyze the data for angular distributions of the inclusive DR cross section, facilitating the determination of the radius parameters of the imaginary DR potential in a less ambiguous manner. Simultaneous X²-analyses are performed of relevant data for the 160+208Pb system near the Coulomb-barrier energy.
6HE+209Bi계의 쿨롱 장벽 에너지 근처에서의 탄성 산란, 붕괴, 융합 단면적 데이터의 광학 모델에 의한 분석
이채호 ; 박수봉 ; 이상덕 ; 소운영 김천대학교 2003 김천대학교 논문집 Vol.24 No.-
Based on an approach proposed to calculate the direct reaction (DR) and fusion probabilities for heavy ion collisions, simultaneous x -analy- ses are performed of data of the elastic scattering, DR and fusion cross sections for the 6He+209B1 system at near-Coulomb-barrier energies, determining parameters of the polarization potential, consisting of DR and fusion parts. We show that the data are well reproduced by the potential that satisfies the dispersion relation. A Discussion is also given of nature of the threshold anomaly of the extracted potential.
Protective Effects of Ecklonia stolonifera Extract on Ethanol-Induced Fatty Liver in Rats
( Chae-young Bang ),( Jae-hyuk Byun ),( Hye-kyung Choi ),( Jae-sue Choi ),( Se-young Choung ) 한국응용약물학회 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.6
Chronic alcohol consumption causes alcoholic liver disease, which is associated with the initiation of dysregulated lipid metabolism. Recent evidences suggest that dysregulated cholesterol metabolism plays an important role in the pathogenesis of alcoholic fatty liver disease. Ecklonia stolonifera (ES), a perennial brown marine alga that belongs to the family Laminariaceae, is rich in phlorotannins. Many studies have indicated that ES has extensive pharmacological effects, such as antioxidative, hepatoprotective, and antiinflammatory effects. However, only a few studies have investigated the protective effect of ES in alcoholic fatty liver. Male Sprague-Dawley rats were randomly divided into normal diet (ND) (fed a normal diet for 10 weeks) and ethanol diet (ED) groups. Rats in the ED group were fed a Lieber-DeCarli liquid diet (containing 5% ethanol) for 10 weeks and administered ES extract (50, 100, or 200 mg/kg/day), silymarin (100 mg/kg/day), or no treatment for 4 weeks. Each treatment group comprised of eight rats. The supplementation with ES resulted in decreased serum levels of triglycerides (TGs), total cholesterol, alanine aminotransferase, and aspartate aminotransferase. In addition, there were decreases in hepatic lipid and malondialdehyde levels. Changes in liver histology, as analyzed by Oil Red O staining, showed that the ES treatment suppressed adipogenesis. In addition, the ES treatment increased the expression of fatty acid oxidation-related genes (e.g., PPAR-α and CPT-1) but decreased the expression of SREBP 1, which is a TG synthesis-related gene. These results suggest that ES extract may be useful in preventing fatty acid oxidation and reducing lipogenesis in ethanol-induced fatty liver.
Bang, Chae-Young,Choung, Se-Young Pharmaceutical Society of Great Britain 2014 Journal of pharmacy and pharmacology Vol.66 No.6
<P>Dietary use of pine bark extract has been associated with reduced risk of inflammation and diabetes. In this study, we investigated the antidiabetic effects of enzogenol, proanthocyanidins-rich bioflavonoid extract derived from the pine bark of New Zealand Pinus radiata trees, using C57BL/KsJ-db/db mice.</P>
Protective Effects of Ecklonia stolonifera Extract on Ethanol-Induced Fatty Liver in Rats
Bang, Chae-Young,Byun, Jae-Hyuk,Choi, Hye-Kyung,Choi, Jae-Sue,Choung, Se-Young The Korean Society of Applied Pharmacology 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.6
Chronic alcohol consumption causes alcoholic liver disease, which is associated with the initiation of dysregulated lipid metabolism. Recent evidences suggest that dysregulated cholesterol metabolism plays an important role in the pathogenesis of alcoholic fatty liver disease. Ecklonia stolonifera (ES), a perennial brown marine alga that belongs to the family Laminariaceae, is rich in phlorotannins. Many studies have indicated that ES has extensive pharmacological effects, such as antioxidative, hepatoprotective, and antiinflammatory effects. However, only a few studies have investigated the protective effect of ES in alcoholic fatty liver. Male Sprague-Dawley rats were randomly divided into normal diet (ND) (fed a normal diet for 10 weeks) and ethanol diet (ED) groups. Rats in the ED group were fed a Lieber-DeCarli liquid diet (containing 5% ethanol) for 10 weeks and administered ES extract (50, 100, or 200 mg/kg/day), silymarin (100 mg/kg/day), or no treatment for 4 weeks. Each treatment group comprised of eight rats. The supplementation with ES resulted in decreased serum levels of triglycerides (TGs), total cholesterol, alanine aminotransferase, and aspartate aminotransferase. In addition, there were decreases in hepatic lipid and malondialdehyde levels. Changes in liver histology, as analyzed by Oil Red O staining, showed that the ES treatment suppressed adipogenesis. In addition, the ES treatment increased the expression of fatty acid oxidation-related genes (e.g., PPAR-${\alpha}$ and CPT-1) but decreased the expression of SREBP 1, which is a TG synthesis-related gene. These results suggest that ES extract may be useful in preventing fatty acid oxidation and reducing lipogenesis in ethanol-induced fatty liver.