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Parkinson’s Disease in Sub-Saharan Africa- A Review of Epidemiology, Genetics and Access to Care.
Uduak Williams,Olivier Bandmann,Richard Walker 대한파킨슨병및이상운동질환학회 2018 Journal Of Movement Disorders Vol.11 No.2
A low prevalence of Parkinson’s disease has been reported in the Sub-Saharan Africa region. Genetic causes and indeed the clinical features of Parkinson’s disease are poorly described. Very few reports have examined the availability and access to evidence-based quality care for people living with Parkinson’s disease in the region. We reviewed all publications focusing on idiopathic Parkinson’s disease from Sub-Saharan Africa published up to May 2016 and observed a prevalence of Parkinson’s disease ranging between 7/100,000 in Ethiopia to 67/100,000 in Nigeria. The most recent community based study reported a mean age at onset of 69.4 years. Infrequent occurrence of mutations in established Parkinson’s disease genes was also observed in the region. Treatments were non-existent or at best irregular. There is also a lack of well trained medical personnel and multidisciplinary teams in most countries in the region. Drugs for treating Parkinson’s disease are either not available or unaffordable. Large-scale genetic and epidemiological studies are therefore needed in Sub-Saharan Africa to provide further insight into the role of genetics and other aetiological factors in the pathogenesis Parkinson’s disease. The quality of care currently available also needs urgent improvement to meet the basis level of care required by Parkinson’s disease patients.
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