A Pilot Study for Developing an Assessment Scale for the Effect of Herbal Medicine in Healthy Children: Open-Label Study with Gami-Jiwhangtang

Bahn Geon-Ho,Kim Chang-Ju,Chung Joo-Ho,Kim Yong-Hee,Paik Eun-Kyung,Park Jae-Hyung The Society of Korean Medicine 2004 대한한의학회지 Vol.25 No.4

Objective : While the demand for herbal medicine has increased continuously, scientific data attesting to pharmacological activity are still insufficient. One important reason, especially in child patients, is the shortage of standardized instruments for clinical research. This study was designed to develop a scale to assess the effect of herbal medicine in children. Methods : The authors chose Gami-jiwhangtang (GJT) as a standard formulation and developed a scale, Bahn's Drug Evaluation Scale (BaDES), for this experiment. Forty-two healthy children, 7 and 8 years old, living in Seoul, Korea, volunteered to use GJT. The experimental group received GJT for 6 weeks, whereas the control group received no medicine. The children's mothers in both groups completed the BaDES on the sixth and twelfth week after GJT was commenced. Results : The experimental group showed a significant improvement in overall physical condition and gastrointestinal function as compared with the control group. Conclusion : These results suggest that BaDES may be a useful assessment tool for measuring the effect of herbal medicine.

Development of a Water-Window X-ray Source Using a Liquid-Nitrogen Jet

B. Ahn,J. Kim,J. Son,B. Kim,D. Kim 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.54 No.1

As a source for a soft X-ray microscope, a liquid-nitrogen jet has been developed and its radiation characteristics have been investigated for various laser parameters, such as the laser pulse energy and duration. The effects of pre-pulse and multiple pulses have also been stud- ied. The focus has been the N VI 1s2-1s2p transition at 2.88 nm. The investigation shows that the laser intensity for the maximum conversion efficiency scales as Im ∝ 1/T^∝, where ∝ = 0.9 ± 0.15. The study of the pre-pulse effect on the conversion effciency shows that a pre-pulse of only 2 mJ enhances the conversion efficiency by 10 - 15 times for the main pulse of 15 - 60 mJ at a delay of 3 - 6 ns. The photon flux is 1.2 × 10^12 photons / (pulse sr) at a delay of 4 ns for a main pulse of 60 mJ with a pre-pulse of 4 - 8 mJ. The study of the multiple pulse effect was done in the 4-pulse configuration. The enhancement of the radiation compared to the accumulation of the radiation intensity of each pulse was observed at a certain delays between 4 pulses, implying that there exists a proper pulse structure for maximum radiation. As a source for a soft X-ray microscope, a liquid-nitrogen jet has been developed and its radiation characteristics have been investigated for various laser parameters, such as the laser pulse energy and duration. The effects of pre-pulse and multiple pulses have also been stud- ied. The focus has been the N VI 1s2-1s2p transition at 2.88 nm. The investigation shows that the laser intensity for the maximum conversion efficiency scales as Im ∝ 1/T^∝, where ∝ = 0.9 ± 0.15. The study of the pre-pulse effect on the conversion effciency shows that a pre-pulse of only 2 mJ enhances the conversion efficiency by 10 - 15 times for the main pulse of 15 - 60 mJ at a delay of 3 - 6 ns. The photon flux is 1.2 × 10^12 photons / (pulse sr) at a delay of 4 ns for a main pulse of 60 mJ with a pre-pulse of 4 - 8 mJ. The study of the multiple pulse effect was done in the 4-pulse configuration. The enhancement of the radiation compared to the accumulation of the radiation intensity of each pulse was observed at a certain delays between 4 pulses, implying that there exists a proper pulse structure for maximum radiation.

NOVEL ANTICARCINOGENIC COMPOUNDS ISOLATED FROM ARTEMISIA CAPILLARIS

Bahn, Kyeong N.,Lee, Eun J.,Lee, Jung M.,Byun, Jae I.,Park, Sook J.,Yang, Min S.,Ha, Yeong L. Plant Molecular Biology & Biotechnology Research C 1994 Plant molecular biology and biotechnology research Vol.1994 No.

Chloroform fraction of hot-methanol soluble materials from Artemisia capaillaris, which inhibited DMBA-induced mouse skin carcinogenesis (Bahn et al., 1993), was further fractionated into F1 fraction by combination of solvent partition and TLC procedures. From the F1 fraction exhibited a strong cytotoxicity (ED_(50):<0.08vg/ml) for both L1210 and S- 180 mouse cancer cells, achillin and its isomer were identified as the major anticarcinogenic compounds.

ISOPERIMETRIC INEQUALITIES FOR SECTORS ON THE MINKOWSKI 2-SPACETIME

Bahn, Hyoungsick,Hong, Sungpyo 경북대학교 위상수학 기하학연구센터 1999 硏究論文集 Vol.8 No.-

In the Minkowski 2-spacetime L^(2) the hyperbolic angle is defined by the hyperbolic parametrization of the plane. With this notion of hyperbolic angle Helzer obtained a relativistic version of Gauss-Bonnet formula (cf. [3]). In this paper, we derive an isoperimetric inequality for timelike sectors in L^(2) bounded by an achronal spacelike curve and two timelike rays from a point using this Gauss-Bonnet formula.

The relationship between microstructural alterations of the brain and clinical measurements in children and adolescents with hair pulling disorder

Bahn, Geon Ho,Hong, Minha,Lee, Kyung Mi,Lee, Chanhee,Ryu, Chang-Woo,Lee, Ji-Ah,Park, Soonchan,Kim, Eui Jong,Jahng, Geon-Ho Springer-Verlag 2018 BRAIN IMAGING AND BEHAVIOR Vol.12 No.2

Application-Adaptive Performance Improvement in Mobile Systems by Using Persistent Memory

Bahn, Hyokyung The Institute of Internet 2019 Journal of Advanced Smart Convergence Vol.8 No.1

In this article, we present a performance enhancement scheme for mobile applications by adopting persistent memory. The proposed scheme supports the deadline guarantee of real-time applications like a video player, and also provides reasonable performances for non-real-time applications. To do so, we analyze the program execution path of mobile software platforms and find two sources of unpredictable time delays that make the deadline-guarantee of real-time applications difficult. The first is the irregular activation of garbage collection in flash storage and the second is the blocking and time-slice based scheduling used in mobile platforms. We resolve these two issues by adopting high performance persistent memory as the storage of real-time applications. By maintaining real-time applications and their data in persistent memory, I/O latency can become predictable because persistent memory does not need garbage collection. Also, we present a new scheduler that exclusively allocates a processor core to a real-time application. Although processor cycles can be wasted while a real-time application performs I/O, we depict that the processor utilization is not degraded significantly due to the acceleration of I/O by adopting persistent memory. Simulation experiments show that the proposed scheme improves the deadline misses of real-time applications by 90% in comparison with the legacy I/O scheme used in mobile systems.

KERNEL OPERATORS ON FOCK SPACE

Bahn, Chang-Soo,Ko, Chul-Ki,Park, Yong-Moon Korean Mathematical Society 1998 대한수학회지 Vol.35 No.3

We study on kernel operators (Wick monomials) on symmetric Fock space. We give optimal conditions on kernels so that the corresponding kernel operators are densely defined linear operators on the Fock space. We try to formulate our results in the framework of white noise analysis as much as possible. The most of the results in this paper can be extended to anti-symmetric Fock space.

CHEMICAL EFFECTS ON PWR SUMP STRAINER BLOCKAGE AFTER A LOSS-OF-COOLANT ACCIDENT: REVIEW ON U.S. RESEARCH EFFORTS

Bahn, Chi Bum Korean Nuclear Society 2013 Nuclear Engineering and Technology Vol.45 No.3

Industry- or regulatory-sponsored research activities on the resolution of Generic Safety Issue (GSI)-191 were reviewed, especially on the chemical effects. Potential chemical effects on the head loss across the debris-loaded sump strainer under a post-accident condition were experimentally evidenced by small-scale bench tests, integrated chemical effects test (ICET), and vertical loop head loss tests. Three main chemical precipitates were identified by WCAP-16530-NP: calcium phosphate, aluminum oxyhydroxide, and sodium aluminum silicate. The former two precipitates were also identified as major chemical precipitates by the ICETs. The assumption that all released calcium would form precipitates is reasonable. CalSil insulation needs to be minimized especially in a plant using trisodium phosphate buffer. The assumption that all released aluminum would form precipitates appears highly conservative because ICETs and other studies suggest substantial solubility of aluminum at high temperature and inhibition of aluminum corrosion by silicate or phosphate. The industry-proposed chemical surrogates are quite effective in increasing the head loss across the debris-loaded bed and more effective than the prototypical aluminum hydroxide precipitates generated by in-situ aluminum corrosion. There appears to be some unresolved potential issues related to GSI-191 chemical effects as identified in NUREG/CR-6988. The United States Nuclear Regulatory Commission, however, concluded that the implications of these issues are either not generically significant or are appropriately addressed, although several issues associated with downstream in-vessel effects remain.

CPC: A File I/O Cache Management Policy for Compute-Bound Workloads

Bahn, Hyokyung The Institute of Internet 2022 International journal of advanced smart convergenc Vol.11 No.2

With the emergence of the new era of the 4th industrial revolution, compute-bound workloads with large memory footprint like big data processing increase dramatically. Even in such compute-bound workloads, however, we observe bulky I/Os while loading big data from storage to memory. Although file I/O cache plays a role of accelerating the performance of storage I/O, we found out that the cache hit rate in such environments is not improved even though we increase the file I/O cache capacity because of some special I/O references generated by compute-bound workloads. To cope with this situation, we propose a new file I/O cache management policy that improves the cache hit rate for compute-bound workloads significantly. Trace-driven simulations by replaying file I/O reference logs of compute-bound workloads show that the proposed cache management policy improves the cache hit rate compared to the well-acknowledged CLOCK algorithm by a large margin.

Metronidazole Induced Encephalopathy in a Patient with Brain Abscess

Bahn, Yoo-Chang,Kim, Eun-Young,Park, Chon-Goon,Park, Hyung-Chun The Korean Neurosurgical Society 2010 Journal of Korean neurosurgical society Vol.48 No.3

Metronidazole is commonly used for brain abscess but is not well known for its neurotoxic complications. Metronidazole-induced encephalopathy (MIEP) is toxic encephalopathy associated with the use of metronidazole. We experienced a case of brain abscess which developed reversible severe MIEP during treatment period. Although MIEP occurs in typical locations, it is not easy to differentiate from other conditions such as cerebral infarction, demyelinating diseases and metabolic diseases. Neurosurgeons should be aware that severe MIEP can occur during the use of metronidazole though it is not common.