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Govindasamy Balasekaran(Balasekaran Govindasamy ),Peggy Boey(Boey Peggy ),Ng Yew Cheo(Cheo Ng Yew) 아시아운동학회 2023 Physical Activity Vol.1 No.1
Children, adolescents, and adults are encouraged to engage in regular physical activities to improve aerobic fitness. To maintain this level of physical activity, it is important that they exercise and play at safe intensities. One method to assess exercise intensity is by using rate of perceived exertion (RPE). The purpose of the review is to identify new perceived exertion scales which were developed for its respective profile and exercise setting. The protocol for the scoping review was drafted and revised by the research team using the PRISMA extension for scoping reviews. Through the review, 13 articles explored the application of RPE in healthy male and female adults, with majority who exercised regularly. Using the systematic approach, the scoping review identified studies that have modified conventional perceived exertion scales for use in different exercise modes for healthy adults. The studies have revealed that use of various elements on a perceived exertion scale are suitable for its intended population and exercise.
Tan, Teik Hin,Boey, Ching Yeen,Lee, Boon Nang 대한핵의학회 2018 핵의학 분자영상 Vol.52 No.2
Purpose The National Cancer Institute is the only referral centre in Malaysia that provides $^{68}Ga$-DOTA-peptide imaging. The purpose of this study is to determine the impact of $^{68}Ga$-DOTA-peptide PET/CT on the management of gastrointestinal neuroendocrine tumours (GI-NET). Materials and Methods A cross-sectional study was performed to review the impact of $^{68}Ga$-DOTA-peptide ($^{68}Ga$-DOTATATE or $^{68}Ga$-DOTATOC) PET/CT on patients with biopsy-proven GI-NET between January 2011 and December 2015. Suspected NET was excluded. Demographic data, tumoral characteristics, change of disease stage, pre-PET intended management and post-PET management were evaluated. Results Over a 5-year period, 82 studies of $^{68}Ga$-DOTA-peptide PET/CT were performed on 44 GI-NET patients. The most common primary site was the rectum (50.0%) followed by the small bowel, stomach and colon. Using WHO 2010 grading, 40.9% of patients had low-grade (G1) tumour, 22.7% intermediate (G2) and 4.5% high (G3). Of ten patients scheduled for pre-operative staging, $^{68}Ga$-DOTA-peptide PET/CT only led to therapeutic change in three patients. Furthermore, false-negative results of $^{68}Ga$-DOTA-peptide PET/CT were reported in one patient after surgical confirmation. However, therapeutic changes were seen in 20/36 patients (55.6%) scheduled for post-surgical restaging or assessment of somatostatin analogue (SSA) eligibility. When $^{68}Ga$-DOTA-peptide PET/CT was used for monitoring disease progress during systemic treatment (sandostatin, chemotherapy, everolimus and PRRT) in metastatic disease, impact on management modification was seen in 19/36 patients (52.8%), of which 84.2% had inter-modality change (switch to everolimus, chemotherapy or PRRT) and 15.8% had intra-modality change (increased SSA dosage). Conclusions $^{68}Ga$-DOTA-peptide PET/CT has a significant impact on management decisions in GI-NET patients as it can provide additional information on occult metastasis/equivocal lesions and supply the clinician an opportunity to select patients for targeted therapy.
Chan, Lai Keng,Dewi, Patra Rina,Boey, P.L. 한국식물학회 2005 Journal of Plant Biology Vol.48 No.1
Cymbopogon nardus L could be propagated via tissue culture using axillary buds as explants. The aseptic bud explants obtained using double sterilization methods produced stunted abnormal multiple shoots when they were cultured on Murashige and Skoog medium (MS) supplemented with 1.0 ㎎ L^(-1) or 2.0 ㎎ L^(-1) benzyladenine (BA). Stunted shoots that cultured on MS + 1.0 ㎎ L^(-1) BA + 1.0 ㎎ N^6-isopentenyl-adenine (2iP) could induce elongation of shoots from about 60% of the stunted shoots. Normal multiple shoots could be induced at the highest (19.7 shoots per bud) from the bud explants within six weeks when cultured on proliferation medium consisted of MS supplemented with 0.3 ㎎ L^(-1) BA + 1.0 ㎎ L^(-1) indole-3-butyric acid (IBA). The separated individual shoot produced roots when transferred to basic MS solid medium. The essential oils that were contained in the mature plants namely citronella), geraniol and citronellol were also found in the in vitro C. nardus plant-lets. Citronella) was the main essential oil component in the matured plants while geraniol was the main component in the in vitro plantlets.
( Chan Chee Weng ),( Chan Lai Keng ),( Boey Peng Lim ) 한국식물학회 2004 Journal of Plant Biology Vol.47 No.3
Juvenile hormone Ⅲ (JH Ⅲ) is one of the five closely related sesquiterpenoid compounds important in the regulation of an insect physiological processes in both the developing and the mature insect. JH Ⅲ and its biosynthetic intermediates, farnesol and methyl farnesoate were detected in the in vitro Cyperus aromaticus plantlets and the mature plants growing in the field. A higher amount of methyl farnesoate (52.7%) and farnesol (31.4%) were found to be present in the in vitro plantlets as compared to the field grown mother plants which contained lower methyl farnesoate (19.5%) and farnesol (14.8%). On the other hand, the mature mother plant (4 months old) contained a higher percentage of JH Ⅲ than the in vitro plantlets. The estimated content of JHⅢ analyzed by gas chromatography indicated that the amount of JHⅢ in the 10 weeks old in vitro plantlets and the four months old mature plants of C. aromaticus was 0.076 ㎍/g and 0.085 ㎍/g respectively. This study indicated that in vitro culture system could be a potential tool for the production of this natural derived bio-insecticide and could provide a material source for further investigations of the biosynthesis of JH Ⅲ in C. aromaticus.
Siregar Luthfi Aziz Mahmud,Chan Lai-Keng,Boey Peng-Lim The Korean Society of Plant Biotechnology 2003 Plant molecular biology and biotechnology research Vol.5 No.2
Callus and cell suspension cultures of Eurycoma longifolia Jack were initiated from leaves of different trees. The leaf explant of tree Eu9 produced the most calli and also induced high cell biomass in the cell suspension culture. Optimum production of cell biomass could be initiated in proliferating culture medium with a pH of 5.75 prior to autoclaving. The effects of macronutrient inorganic salts of Murashige and Skoog (MS) liquid medium supplemented with X on production of cell biomass of Eurycoma longifolia were also investigated. The highest cell biomass was produced in MS medium containing macronutrients of $21\;mM\;NH_4NO_3,\;12.25\;mM\;KNO_3,\;3.00\;mM\;CaCl_2.2H_2O,\;0.575\;mM\;MgSO_4.7H_2O$, and $1.83\;mM\;KH_2PO_4$. A new medium labeled as TAM was formulated for the production of Eurycoma longifolia cell biomass in the cell suspension culture.
He, Qiyuan,Sudibya, Herry Gunadi,Yin, Zongyou,Wu, Shixin,Li, Hai,Boey, Freddy,Huang, Wei,Chen, Peng,Zhang, Hua American Chemical Society 2010 ACS NANO Vol.4 No.6
<P>Recently, the field-effect transistors (FETs) with graphene as the conducting channels have been used as a promising chemical and biological sensors. However, the lack of low cost and reliable and large-scale preparation of graphene films limits their applications. In this contribution, we report the fabrication of centimeter-long, ultrathin (1−3 nm), and electrically continuous micropatterns of highly uniform parallel arrays of reduced graphene oxide (rGO) films on various substrates including the flexible polyethylene terephthalate (PET) films by using the micromolding in capillary method. Compared to other methods for the fabrication of graphene patterns, our method is fast, facile, and substrate independent. In addition, we demonstrate that the nanoelectronic FETs based on our rGO patterns are able to label-freely detect the hormonal catecholamine molecules and their dynamic secretion from living cells.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2010/ancac3.2010.4.issue-6/nn100780v/production/images/medium/nn-2010-00780v_0001.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn100780v'>ACS Electronic Supporting Info</A></P>