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Bian Jing-Yang,Guo Xiao-Yu,Lee Dong Hun,Sun Xing-Rong,Liu Lin-Shuai,Shao Kai,Liu Kai,Sun Hu-Nan,Kwon Taeho 한국응용생명화학회 2024 Applied Biological Chemistry (Appl Biol Chem) Vol.67 No.-
Recently, non-thermal plasma (NTP) technologies have found widespread application across diverse fields, including plant growth, medical science, and biological and environmental research. Rice (Oryza sativa L.) is exceptionally sensitive to temperature changes. Notably, low-temperature stress primarily affects the germination and reproductive stages of rice, often leading to reduced crop yield. This study aimed to identify optimal conditions for enhancing rice seed germination and seedling growth under low temperatures using NTP technology. Our research indicated that NTP treatment at 15.0 kV for 30 s optimally promotes rice seed germination and growth under low-temperature stress. Furthermore, NTP treatment increases the activity and expression of antioxidant enzymes, such as superoxide dismutase (SOD), catalase (CAT), and peroxidase (POD), under low-temperature conditions. Moreover, it downregulates the expression of β-ketoacyl-[acyl carrier protein] synthase I (KASI) and cis-epoxy carotenoid dioxygenase 3 (NCED3) and upregulates the expression of alternative oxidase (AOX1B), BREVIS RADIX-like homologous gene (BRXL2), WRKY transcription factor 29 (WRKY29), and EREBP transcription factor 2 (EREBP2) in roots after tandem 7 days lowtemperature (16 ℃) and 7 days room-temperature (28 ℃) treatments. Transcriptomic analysis revealed the involvement of various key genes in phosphotransferase activity, phosphate-containing compound metabolic processes, and defense responses. These analyses provide comprehensive information on gene expression at the transcriptional level, offering new insights for a deeper understanding of candidate genes required for root growth in rice.
Clinical Applicability of Multi-Tumor Marker Protein Chips for Diagnosing Ovarian Cancer
Bian, Jing,Li, Bo,Kou, Xian-Juan,Wang, Xu-Na,Sun, Xiao-Xu,Ming, Liang Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.19
Purpose: To assess the value of multi-tumor marker protein chips in the diagnosis and treatment of ovarian cancer. Materials and Methods: Twelve tumor markers (CA19-9, NSE, CEA, CA242, CK19, ${\beta}$-HCG, AFP, SCC, c-PSA, CA125, CA724 and CA15-3) were detected by protein biochip in 220 patients with ovarian carcinomas, 205 with benign ovarian tumors and 200 healthy subjects. Results: The positivity rate was obviously higher in ovarian cancer (77.7%), than that in the benign cases (26.3%, p<0.01) and healthy subjects (4.5%, p<0.01). Serum levels of tumor markers were furthermore significantly higher in cases with lymph node metastasis (86.8%) than those without metastasis (44.7%), p<0.01. Conclusions: Multi-tumor marker protein chips provide important assistance in the diagnosis and treatment evaluation in ovarian cancers.
CP violation effects in the diphoton spectrum of heavy scalars
Bian, Ligong,Chen, Ning,Zhang, Yongchao American Physical Society 2017 Physical Review D Vol.96 No.9
<P>In a class of new physics models, an extended Higgs sector and new CP-violating sources are simultaneously present in order to explain the baryon asymmetry in the Universe. The aim of this work is to study the implications of beyond the Standard Model (SM) CP violation for the searches of heavy scalars at the LHC. In particular, we focus on the diphoton channel searches in the CP-violating two-Higgs-doublet model (CPV 2HDM). To have a sizable CPV in the scalar sector, the two heavy neutral scalars in 2HDM tend to be nearly degenerate. The theoretical constraints of unitarity, perturbativity and vacuum stability are considered, which requires that the heavy scalars M-H less than or similar to 1 TeV in a large region of the parameter space. The experimental limits are also taken into account, including the direct searches for heavy neutral scalars in the final state of the SM h, W and Z bosons; the differential (tt) over bar data; those from the charged scalar sector which is implied by the oblique T parameter; and the precise measurements of the electric dipole moments of electrons and mercury. The quantum interference effects between the resonances and the SM background are crucially important for the diphoton signals, and the CPV mixing of the quasidegenerate heavy scalars could enhance significantly the resonance peak. With an integrated luminosity of 3000 fb(-1) at the LHC, almost the whole parameter space of CPV 2HDM could be probed in the diphoton channel, and the CPV could also be directly detected via the diphoton spectrum.</P>
Future prospects of mass-degenerate Higgs bosons in the CP -conserving two-Higgs-doublet model
Bian, Ligong,Chen, Ning,Su, Wei,Wu, Yongcheng,Zhang, Yu American Physical Society 2018 Physical Review D Vol.97 No.11
<P>The scenario of two mass-degenerate Higgs bosons within the general two-Higgs-doublet model (2HDM) is revisited. We focus on the global picture when two CP-even Higgs bosons of h and H are nearly mass-degenerate. A global fit to the signal strength of the 125 GeV Higgs measured at the LHC is performed. Based on the best-fit result of the 2HDM mixing angles (alpha, beta), theoretical constraints, charged and CP-odd Higgs boson direct search constraints and the electroweak precision constraints are imposed to the 2HDM parameter space. We present the signal predictions of the (4b, 2b2 gamma) channels for the benchmark models at the LHC 14 TeV runs. We also study the direct Higgs boson pair productions at the LHC, and the Z-associated Higgs boson pair production search at the ILC 500 GeV runs, as well as the indirect probes at the CEPC 250 GeV run. We find that the massdegenerate Higgs boson scenario in the Type-II 2HDM can be fully probed by these future experimental searches.</P>
Axisymmetrical bending of single- and multi-span functionally graded hollow cylinders
Bian, Z.G.,Wang, Y.H. Techno-Press 2013 Structural Engineering and Mechanics, An Int'l Jou Vol.45 No.3
Single- and multi-span orthotropic functionally graded hollow cylinders subjected to axisymmetrical bending are investigated on the basis of a unified shear deformable shell theory, in which the transverse displacement is expressed by means of a general shape function. To approach the through-thickness inhomogeneity of the hollow cylinder, a laminated model is employed. The shape function therefore shall be determined for each fictitious layer. To improve the computational efficiency, we resort to a transfer matrix method. Based on the principle of minimum potential energy, equilibrium equations are established, which are then solved analytically using the transfer matrix method for arbitrary boundary conditions. Numerical comparisons among a third-order shear deformable shell theory, an exact elastic theory and the present theory are provided for a simply supported hollow cylinder, from which the present theory turns out to be superior in stress estimation. Distributions of displacements and stresses in single- and three-span hollow cylinders with different boundary conditions are also illustrated in numerical examples.