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      • KCI등재

        STUDY OF ROTATIONAL BAND STRUCTURE OF EVEN-EVEN 132;134SM NUCLEI

        ARUN GUPTA,SURBHI GUPTA,SIMI GUPTA,SURAM SINGH,ARUN BHARTI 장전수학회 2021 Proceedings of the Jangjeon mathematical society Vol.24 No.4

        The study of neutron-decient nuclei in the A130 mass region has been an interesting subject in nuclear structure physics as this region is considered to be transitional region. In the present work, the positive parity rotational band structure of even-even 132,134Sm up to the high spin states has been studied in a microscopic frame work of calculations known as Projected Shell Model (PSM). Yrast spectra for 132,134Sm have been obtained from the PSM calculations and has been found to be in good agreement with the available experimental data. Besides this, the present calculations have also reported the occurrence of back bending at the same spins at which experimental data shows in both the nuclei.

      • SCIESCOPUSKCI등재

        Guava (Psidium guajava L.) Powder as an Antioxidant Dietary Fibre in Sheep Meat Nuggets

        Verma, Arun K.,Rajkumar, V.,Banerjee, Rituparna,Biswas, S.,Das, Arun K. Asian Australasian Association of Animal Productio 2013 Animal Bioscience Vol.26 No.6

        This study was conducted to explore the antioxidant potential and functional value of guava (Psidium guajava L.) powder in muscle foods. Guava powder was used as a source of antioxidant dietary fibre in sheep meat nuggets at two different levels i.e., 0.5% (Treatment I) and 1.0% (Treatment II) and its effect was evaluated against control. Guava powder is rich in dietary fibre (43.21%), phenolics (44.04 mg GAE/g) and possesses good radical scavenging activity as well as reducing power. Incorporation of guava powder resulted in significant decrease (p<0.05) in pH of emulsion and nuggets, emulsion stability, cooking yield and moisture content of nuggets while ash and moisture content of emulsion were increased. Total phenolics, total dietary fibre (TDF) and ash content significantly increased (p<0.05) in nuggets with added guava powder. Product redness value was significantly improved (p<0.05) due to guava powder. Textural properties did not differ significantly except, springiness and shear force values. Guava powder was found to retard lipid peroxidation of cooked sheep meat nuggets as measured by TBARS number during refrigerated storage. Guava powder did not affect sensory characteristics of the products and can be used as source of antioxidant dietary fibre in meat foods.

      • KCI등재

        Hot stage microscopy and its applications in pharmaceutical characterization

        Kumar Arun,Singh Pritam,Nanda Arun 한국현미경학회 2020 Applied microscopy Vol.50 No.1

        Hot stage microscopy (HSM) is a thermal analysis technique that combines the best properties of thermal analysis and microscopy. HSM is rapidly gaining interest in pharmaceuticals as well as in other fields as a regular characterization technique. In pharmaceuticals HSM is used to support differential scanning calorimetry (DSC) and thermo-gravimetric analysis (TGA) observations and to detect small changes in the sample that may be missed by DSC and TGA during a thermal experiment. Study of various physical and chemical properties such sample morphology, crystalline nature, polymorphism, desolvation, miscibility, melting, solid state transitions and incompatibility between various pharmaceutical compounds can be carried out using HSM. HSM is also widely used to screen cocrystals, excipients and polymers for solid dispersions. With the advancements in research methodologies, it is now possible to use HSM in conjunction with other characterization techniques such as Fourier transform infrared spectroscopy (FTIR), DSC, Raman spectroscopy, scanning electron microscopy (SEM) which may have additional benefits over traditional characterization techniques for rapid and comprehensive solid state characterization.

      • KCI등재

        Microphysiological system with continuous analysis of albumin for hepatotoxicity modeling and drug screening

        Arun Asif,박성혁,Afaque Manzoor Soomro,Muhammad Asad Ullah Khalid,Abdul Rahim Chattikatikatuveli Salih,강보혜,Faheem Ahmed,김경환,최경현 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.98 No.-

        In microfluidics, the emergingfield of microphysiological systems (MPS) is overcoming the challenge ofphysiological irrelevancy by animal models for drug discovery and development. Liver function iscritically influenced by drugs owing to its role in drug metabolism and detoxification. Human serumalbumin (HSA) is one of the most important secreted biomarkers which indicate normal liver function. Amicrofluidic albumin immunosensor was developed to be integrated with liver-on-a-chip MPS forcontinuous feedback over disease modeling and treatment. A gold-electrode based electrochemicalimmunosensor was established by anti-HSA antibody immobilization. The liver MPS was found to beefficient for live monitoring of disease modelling and drug treatment over the period of 6 days. Thesystem emulated and analyzed real-time toxicity modeling with HSA sensing. The detection limit ofintegrated sensor was 1 mg/ml with successive reproducibility. The proposed sensor was also validatedwith metabolic biomarkers’ assays. Molecular assays supported the sensor monitoring and depicted liverinjury and recovery. The liver MPS with combined albumin sensor chip may be a promising platform tomimic real-time drug assessment.

      • KCI등재

        A Novel Scale for Assessing the Burden of Caregiving for Functionally Compromised Patients: Proposal and Validation

        Arun-Kumar Kaliya-Perumal,Anupama Korlakunta,Jacquilyne Kharlukhi,Sarada Devireddy 대한가정의학회 2021 Korean Journal of Family Medicine Vol.42 No.1

        Background: Disability not only burdens the patient, but also the caregiver. To quantify this caregiving burden, we propose a simple four-part questionnaire tool. Our objective is to validate this questionnaire by administering it to caregivers who oversee patients with low back pain and are functionally compromised. Methods: Twenty-five spouse caregivers who were taking care of in-patients awaiting surgery for various lumbar spine pathologies were shortlisted. The content-validated questionnaire was administered on different occasions during the care recipient’s treatment. Cronbach’s α was calculated to assess internal consistency. Interrelationships between the care recipient’s pain score, extent of functional compromise, and caregiver burden were calculated. The questionnaire’s ability to track changes in the caregivers’ attitudes over time was assessed. Results: The percentage of caregiver burden before the surgery of the care recipient was 52.5. This increased significantly to 61.1% (P=0.001) 3 days after surgery, but was found to decrease to 32.5% (P<0.001) a month after the surgery; demonstrating the questionnaire’s efficacy to track changes. Cronbach’s alpha of 0.948 signifies the questionnaire’s excellent internal consistency. Pearson’s correlation coefficient (r) between the care recipient’s pain score and caregiver’s burden score was 0.41 (P=0.04), and between the care recipient’s disability score and caregiver’s burden score was 0.9 (P<0.001). Conclusion: The proposed questionnaire is consistent and can track changes in a caregiver’s attitude over time. It can be adopted for clinical use to assess the burden of caregiving for functionally compromised patients.

      • KCI등재

        In vitro antibacterial activity of Hibiscus rosa sinensis, Chrysanthemum indicum, and Calendula officinalis flower extracts against Gram negative and Gram positive food poisoning bacteria

        Arun Karnwal 경희대학교 융합한의과학연구소 2022 Oriental Pharmacy and Experimental Medicine Vol.22 No.3

        Safely management of food spoilage and foodborne illness is primarily achieved by applying chemical additives that have adverse effects along with health risk, increment chemical in food, and reduced bacterial susceptibility to antimicrobials. In the present study, antimicrobial efficacy of extracts from 3 different flowers (Hibiscus rosa sinensis, Chrysanthemum indicum, and Calendula officinalis) was examined towards seven food poisoning bacterial strains, four gram-positive strains (Staphylococcus aureus MTCC 87, Bacillus cereus MTCC 430, Clostridium perfringens MTCC 450, Listeria monocytogenes MTCC 657), and three gram-negative strains (Escherichia coli MTCC 43, Salmonella typhi MTCC 1264 and Pseudomonas aeruginosa MTCC424) using well diffusion assay. Aqueous extracts from all three of the flowers were similarly efficient with variable antimicrobial efficiency against the examined bacterial strains, while ethanol and methanol extracts from C. officinalis were highly efficient against all tested pathogenic bacteria. Ethanolic extract of C. indicum was the most efficient flower extract after C. officinalis against C. perfringens, L. monocytogenes, and S. typhi. H. rosa sinensis ethanol extract exhibited bactericidal action against S. aureus, B. cereus, and P. aeruginosa. For most extracts, the minimum inhibitory concentration (MIC) ranged from 3.75 to 7.5% and minimum bactericidal concentration (MBC) of 1.87–3.75% except for C. perfringens, and L. monocytogenes those were less sensitive with MIC 20%, and MBC 20%. Such flower extracts, which are potentially efficient, would be utilized to manage foodborne illness and protect food items from spoilage and minimize safety hazards generated due to chemically preservatives.

      • KCI등재

        Chemical processing strategies to obtain sporopollenin exine capsules from multi-compartmental pine pollen

        Arun Kumar Prabhakar,Hui Ying Lai,Michael G. Potroz,Michael K. Corliss,박재현,Raghavendra C. Mundargi,조대호,방사익,조남준 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.53 No.-

        Pine pollen is widely used in traditional Chinese medicine and has been consumed as a food product for thousands of years. Owing to wind pollination, its pollen grains are composed of a sporoplasmic central cavity along with two empty air sac compartments. While this architectural configuration is evolutionarily optimized for wind dispersal, such features also lend excellent potential for encapsulating materials, especially in the context of preparing sporopollenin exine capsules (SECs). Herein, we systematically evaluated one-pot acid processing methods in order to generate pine pollen SECs that support compound loading. Morphological properties of the SECs were analysed by scanning electron microscopy (SEM) and dynamic imaging particle analysis (DIPA), and protein removal was evaluated by CHN elemental analysis and confocal laser scanning microscopy (CLSM). It was identified that 5-h acidolysis with 85% w/v phosphoric acid at 70 C yielded an optimal balance of high protein removal and preservation of microcapsule architecture, while other processing methods were also feasible with an additional enzymatic step. Importantly, the loading efficiency of the pine pollen SECs was three-times greater than that of natural pine pollen, highlighting their potential for microencapsulation. Taken together, our findings outline a successful strategy to prepare intact pine pollen SECs and demonstrate for the first time that SECs can be prepared from multi-compartmental pollen capsules, opening the door to streamlined processing approaches to utilize pine pollen microcapsules in industrial applications.

      • CFD Study on Shock-Boundary Layer Interaction Characteristics over a Rough Wall

        Arun Kumar R,Heuy Dong Kim 한국추진공학회 2013 한국추진공학회 학술대회논문집 Vol.2013 No.5

        Shock wave boundary layer interaction flows are often occurred in many high speed engineering devices. These interactions bring many salient features on the local as well as the whole flow field. In past few decades, much understanding has been obtained on the major characteristics of the shock wave boundary layer interaction such as boundary layer separation, reattachment, shock unsteadiness, the interaction length, etc. The shock boundary layer characteristics depends on many parameters like upstream Mach number, Reynolds number, boundary layer characteristics etc, which has been pointed out by many past studies. The surface roughness effect can significantly modify the shock boundary layer characteristics which have not been studied much in the past. For the present study a 2-D CFD study was carried out to simulate the experimental study of Inger and to explore the effect of surface roughness on the shock boundary layer interaction flow field such as separation point, interaction length etc. The accuracy of different turbulence model in predicting the flow physics were also compared. It can be observed that the omega based model predicts the shock interaction under roughness effect more accurately compared to the wall function based k-epsilon and Reynolds stress model. From the results it can also be observed that the upstream influence increases and the shock strength decreases as the wall surface roughness increases. The separation zone decreases with increase in surface roughness due to the reduction in shock strength.

      • KCI등재

        OFDM system with cyclostationary feature detection spectrum sensing

        Arun Kumar,NandhaKumar P. 한국통신학회 2019 ICT Express Vol.5 No.1

        In Orthogonal Frequency Division Multiplexing OFDM, a cyclic prefix (CP) is applied to reduce the intervention between symbols. The CP results in bandwidth wastage, and the solution to this problem leads to the cognitive radio. In the first part of the work, OFDM with CP is presented and integrated with cyclostationary spectrum sensing. Subsequently, OFDM with cyclostationary spectrum sensing without CP is proposed with the function of the filter at the transmitter and receiver being to utilize the bandwidth that is wasted in the CP phase. The Bit Error Rate BER, signal probability detection, false alarm, and error probability are obtained and analyzed.

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