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Seyda Erdogan,Arbil Acikalin,Handan Zeren,Gulfılız Gonlusen,Suzan Zorludemir,Volkan Izol 대한병리학회 2014 Journal of Pathology and Translational Medicine Vol.48 No.3
Well-differentiated papillary mesothelioma is an uncommon tumor of the testes that usually presents as a hydrocele. Here, we present the case of one patient who did not have a history of asbestos exposure. The tumor was localized in the tunica vaginalis and was composed of three pedunculated masses macroscopically. Microscopically, branching papillary structures with focal coagulative necrosis were present. In addition to immunohistochemistry, simian virus 40 DNA was also tested by polymerase chain reaction. This report presents one case of this rare entity, its clinical and macroscopic features, and follow-up results.
A New Approach to the Treatment of Metastatic Paraganglioma: Sorafenib
Meral Gunaldi,Ismail Oguz Kara,Berna Bozkurt Duman,Cigdem Usul Afsar,Melek Ergin,Arbil Avci 대한암학회 2014 Cancer Research and Treatment Vol.46 No.4
Paragangliomas are relatively rare chromaffin cell tumors which may be cured throughresection. Patients with paragangliomas may develop metastatic diseases. There isno consensus regarding refractory chemotherapy for treatment of metastatic disease. In this report, we presented a case of a 43-year-old woman who was admitted to thehospital with a history of episodic headaches, diaphoresis, and weakness. Elevatedplasma catecholamine levels and a right paraaortic mass were observed on computedtomography. The mass was excised, and a diagnosis of paraganglioma was confirmed. After 20 months of follow-up, local recurrence and metastases were detected in thethorax, abdomen, and skeletal system. Plasma and urinary catecholamine levels werehigh. Chemotherapy was administered, and no improvement was observed. Therefore,following this palliative conventional chemotherapy, sorafenib was administered forthree months, and, finally, positron emission tomography showed that the patient’slesions had completely regressed.