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      • KCI등재

        Analysis of Molecular Variance and Population Structure in Southern Indian Finger Millet Genotypes Using Three Different Molecular Markers

        Host Antony David Rajendran,Ramakrishnan Muthusamy,Antony Caesar Stanislaus,Thirugnanasambantham Krishnaraj,Sivasankaran Kuppusamy,Savarimuthu Ignacimuthu,Naif Abdullah Al-Dhabi 한국작물학회 2016 Journal of crop science and biotechnology Vol.19 No.4

        The genetic relationship among 42 genotypes of finger millet collected from different geographical regions of southern India was investigated using random amplified polymorphic DNA (RAPD), inter simple sequence repeats (ISSR), and simple sequence repeats (SSR) markers. Ten RAPD primers produced 111 polymorphic bands. Five ISSR primers produced a total of 61 bands. Of these, 23 bands were polymorphic. The RAPD and ISSR fingerprints revealed 71.3 and 37.4% polymorphic banding patterns, respectively. Thirty-six SSR primers yielded 83 scorable alleles in which 62 were found to be polymorphic. Out of 36 SSR primers used, 14 primers (46.6%) produced polymorphic bands. The SSR primer UGEP7 produced a maximum number of six alleles. Mean polymorphic information content (PIC) of RAPD, ISSR and SSR were 0.44, 0.28, and 0.14, respectively. Molecular variances among the population were 2, 11, and 1% for RAPD, ISSR, and SSR markers, respectively. SSR produced 99% molecular variance within individuals. RAPD and ISSR markers produced a low level of molecular variance within individuals. The STRUCTURE (model-based program) analysis revealed that the 42 finger millet genotypes could be divided into a maximum of four subpopulations. Based on the Bayesian statistics, each RAPD and SSR marker produced three subpopulations (K=3), while ISSR marker showed four subpopulations (K=4). This study revealed that RAPD and SSR markers could narrow down the analysis of population structure and it may form the basis for finger millet breeding and improvement programs in the future.

      • SCOPUSKCI등재
      • KCI등재후보

        Direct numerical simulations of viscoelastic turbulent channel flows at high drag reduction

        Antony N. Beris,Kostas D. Housiadas 한국유변학회 2005 Korea-Australia rheology journal Vol.17 No.3

        In this work we show the results of our most recent Direct Numerical Simulations (DNS) of turbulent viscoelastic channel flow using spectral spatial approximations and a stabilizing artificial diffusion in the viscoelastic constitutive model. The Finite-Elasticity Non-Linear Elastic Dumbbell model with the Peterlin approximation (FENE-P) is used to represent the effect of polymer molecules in solution. The corresponding rheological parameters are chosen so that to get closer to the conditions corresponding to maximum drag reduction: A high extensibility parameter (60) and a moderate solvent viscosity ratio (0.8) are used with two different friction Weissenberg numbers (50 and 100). We then first find that the corresponding achieved drag reduction, in the range of friction Reynolds numbers used in this work (180-590), is insensitive to the Reynolds number (in accordance to previous work). The obtained drag reduction is at the level of 49% and 63%, for the friction Weissenberg numbers 50 and 100, respectively. The largest value is substantially higher than any of our previous simulations, performed at more moderate levels of viscoelasticity (i.e. higher viscosity ratio and smaller extensibility parameter values). Therefore, the maximum extensional viscosity exhibited by the modeled system and the friction Weissenberg number can still be considered as the dominant factors determining the levels of drag reduction. These can reach high values, even for of dilute polymer solution (the system modeled by the FENE-P model), provided the flow viscoelasticity is high, corresponding to a high polymer molecular weight (which translates to a high extensibility parameter) and a high friction Weissenberg number. Based on that and the changes observed in the turbulent structure and in the most prevalent statistics, as presented in this work, we can still rationalize for an increasing extensional resistance-based drag reduction mechanism as the most prevalent mechanism for drag reduction, the same one evidenced in our previous work: As the polymer elasticity increases, so does the resistance offered to extensional deformation. That, in turn, changes the structure of the most energy-containing turbulent eddies (they become wider, more well correlated, and weaker in intensity) so that they become less efficient in transferring momentum, thus leading to drag reduction. Such a continuum, rheology-based, mechanism has first been proposed in the early 70s independently by Metzner and Lamley and is to be contrasted against any molecularly based explanations.

      • KCI등재

        A note on vertex pair sum $k$-zero ring labeling

        Antony Sanoj Jerome,K.R. Santhosh Kumar,T.J. Rajesh Kumar 한국전산응용수학회 2024 Journal of applied mathematics & informatics Vol.42 No.2

        Let $G=(V,E)$ be a graph with $p$-vertices and $q$-edges and let $R^{\circ}$ be a finite zero ring of order $n$. An injective function $f:V(G)\to \{r_1,r_2,\ldots,r_k\}$, where $r_i\in R^\circ$ is called vertex pair sum $k$-zero ring labeling, if it is possible to label the vertices $x\in V$ with distinct labels from $R^{\circ}$ such that each edge $e=uv$ is labeled with $f(e=uv)=[f(u)+f(v)] \pmod n$ and the edge labels are distinct. A graph admits such labeling is called vertex pair sum $k$-zero ring graph. The minimum value of positive integer $k$ for a graph $G$ which admits a vertex pair sum $k$-zero ring labeling is called the vertex pair sum $k$-zero ring index denoted by $\psi_{pz}(G)$. In this paper, we defined the vertex pair sum $k$-zero ring labeling and applied to some graphs.

      • The Aging of Signalling Equipment and the Impact on Maintenance Strategies

        Antoni, Marc The Korean Society for Railway 2009 International Journal of Railway Vol.2 No.3

        Research projects of SNCF aim at reducing the costs of infrastructure possessions and improving the operational equipment availability and safety. This permanent search for a better regularity led the SNCF to analyse the maintenance approach of signalling equipment in detail. Until now, it was commonly acknowledged that signalling equipment, which consists of many electronic devices, is not subject to aging. In this study, a Weibull lifetime model, able to describe an aging phenomenon, is used and it can be shown that the deterioration is statistically significant. The validity of the model is tested. We also analyse the influence of environmental covariates. We simulate different scenarios in order to investigate the impact of several maintenance strategies as well as on future maintenance costs, on the amount of components to replace based on the mean age of the network. It can be shown that in most cases a systematic replacement strategy offers the best solution.

      • SCOPUSKCI등재

        The New Regionalism in the Americas: The Case of Mercosur

        ( Antoni Esteradeordal ),( Junichi Goto ),( Raul Saez ) 세종대학교 경제통합연구소 (구 세종대학교 국제경제연구소) 2001 Journal of Economic Integration Vol.16 No.2

        This paper takes seriously the recent claim made by Ethier (1998) that the New Regionalism reflects the success of the multilateral trading system, not its failure. In fact, the New Regionalism represents a qualitative departure of the old regionalism in several respects, in particular, its development has taken place in a very different international economic environment. Moreover, the traditional Vinerian paradigm is no longer the primary analytical framework for its evalua-tion. We use this novel approach to analyze the case of one of the most important experiences in regional integration, the formation of the Mercado Comun del Sur (MERCOSUR). The paper carefully documents the main stylized facts of the development of MERCOSUR arguing that this makes this type of agreement a prime example of the New Regionalism. Our conclusions are consistent with Ethier`s paper, that is, regionalism can play a key role in expanding and preserving the liberal trade order.

      • KCI등재

        Economic Impact of Combining Metformin with Dipeptidyl Peptidase-4 Inhibitors in Diabetic Patients with Renal Impairment in Spanish Patients

        Antoni Sicras-Mainar,Ruth Navarro-Artieda 대한당뇨병학회 2015 Diabetes and Metabolism Journal Vol.39 No.1

        Background: To evaluate resource use and health costs due to the combination of metformin and dipeptidyl peptidase-4 (DPP-4) inhibitors in patients with diabetes and renal impairment in routine clinical practice. Methods: An observational, retrospective study was performed. Patients aged ≥30 years treated with metformin who initiated a second oral antidiabetic treatment in 2009 to 2010 were included. Two groups of patients were analysed: metformin+DPP-4 inhibitors and other oral antidiabetics. The main measures were: compliance, persistence, metabolic control (glycosylated hemoglobin<7%) and complications (hypoglycemia, cardiovascular events) and total costs. Patients were followed up for 2 years. Results: We included 395 patients, mean age 70.2 years, 56.5% male: 135 patients received metformin+DPP-4 inhibitors and 260 patients received metformin+other oral antidiabetics. Patients receiving DPP-4 inhibitors showed better compliance (66.0% vs. 60.1%), persistence (57.6% vs. 50.0%), and metabolic control (63.9% vs. 57.3%), respectively, compared with those receiving other oral antidiabetics (P<0.05), and also had a lower rate of hypoglycemia (20.0% vs. 47.7%) and lower total costs (€ 2,486 vs. € 3,002), P=0.001. Conclusion: Despite the limitations of the study, patients with renal impairment treated with DPP-4 inhibitors had better metabolic control, lower rates (association) of hypoglycaemia, and lower health costs for the Spanish national health system.

      • VSimulators: A New UK-based Immersive Experimental Facility for Studying Occupant Response to Wind-induced Motion of Tall Buildings

        Antony Darby,James Brownjohn,Erfan Shahabpoor,Kaveh Heshmati Council on Tall Building and Urban Habitat Korea 2022 International journal of high-rise buildings Vol.11 No.4

        Current vibration serviceability assessment criteria for wind-induced vibrations in tall buildings are based largely on human 'perception' thresholds which are shown not to be directly translatable to human 'acceptability' of vibrations. There is also a considerable debate about both the metrics and criteria for vibration acceptability, such as frequency of occurrence or peak vs mean vibration, and how these might vary with the nature of the vibration. Furthermore, the design criteria are necessarily simplified for ease of application so cannot account for a range of environmental, situational and human factors that may enhance or diminish the impact of vibrations on serviceability. The dual-site VSimulators facility was created specifically to provide an experimental platform to address gaps in understanding of human response to building vibration. This paper considers how VSimulators can be used to inform general design guidance and support design of specific buildings for habitability, in terms of vibration, which allow engineers and clients to make informed decisions with regard to sustainable design, in terms of energy and financial cost. This paper first provides a brief overview of current vibration serviceability assessment guidelines, and the current understanding and limitations of occupants' acceptability of wind-induced motion in tall buildings. It then describes how the dual-site VSimulators facility at the Universities of Bath and Exeter can be used to assess the effects of motion and environment on human comfort, wellbeing and productivity with examples of how the facility capabilities have been used to provide new, human experience based experimental research approaches.

      • SCOPUSKCI등재

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