Straight lift technique as an alternative to surgical extraction of an intact, partially impacted mesioangular mandibular third molar

Anshul J. Rai(Anshul J. Rai ),Jitendra Kumar(Jitendra Kumar ),Babu Lal(Babu Lal ),Prateek Shakti(Prateek Shakti ) 대한구강악안면외과학회 2022 대한구강악안면외과학회지 Vol.48 No.5

Impacted mandibular third molar removal is the most common procedure performed by oral and maxillofacial surgeons. An array of alternative pro-cedures have been suggested, like operculectomy in cases of pericoronitis and coronectomy in certain cases. However, these procedures pose several disadvantages, and we propose a relatively non-invasive ‘straight lift technique’. This technique is specifically useful in straightening abnormally posi-tioned mesioangular third molars as a substitute of complete removal. This can improve tooth function, eliminate the need for surgical intervention, and reduce the risk of complications associated with third molar removal.

Design of an FPGA Based Controller for Delta Modulated Single-Phase Matrix Converters

Anshul Agarwal,Vineeta Agarwal 전력전자학회 2012 JOURNAL OF POWER ELECTRONICS Vol.12 No.6

A FPGA based delta modulated single phase matrix converter has been developed that may be used in both cyclo-converters and cyclo-inverters. This converter is ideal for variable speed electrical drives, induction heating, fluorescent lighting, ballasts and high frequency power supplies. The peripheral input-output and FPGA interfacing have been developed through Xilinx 9.2i, to generate delta modulated trigger pulses for the converter. The controller has been relieved of the time consuming computational task of PWM signal generation by implementing the method of trigger pulse generation in a FPGA by using Hardware Description Language VHDL in Xilinx. The trigger circuit has been tested qualitatively by observing various waveforms on an oscilloscope. The operation of the proposed system has been found to be satisfactory.

Role of fumarates in adaptogenics like efficacies of traditionally used Fumaria indica extracts

Anshul Shakya,Shyam Sunder Chatterjee,Vikas Kumar 셀메드 세포교정의약학회 2015 셀메드 (CellMed) Vol.5 No.1

Fumaria indica Linn. (Syn: Fumaria parviflora, Fumariaceae) is a wildly grown weed, mentioned and recommended in classical Ayurvedic texts for treatments of variety of ailments including dermatological diseases, topical diseases, cardiovascular complaints, circulatory disease, fever and headache etc. The present pilot study was designed to experimentally verify the possibility that fumarates are the major bioactive principles of Fumaria indica extracts involved in their stress response modulating activities, and to estimate pharmacologically active dose ranges of fumarates and standardized methanolic extract of Fumaria indica (MFI). Effect of single, 5 and 10 daily oral doses of pure fumaric acid (FA), monomethyl fumarate (MMF), dimethyl fumarate (DMF) and MFI was quantified in well validated rodent models viz. apomorphine induced cage climbing, stress induced hyperthermia, and elevated plus-maze tests. Obtained results reveal high efficacy of MFI and pure fumarates possess qualitatively analogous activity profiles in all the three tests. There were no significant difference in the potencies of pure FA, MMF and DMF in the three tests, whereas efficacy of MFI in the elevated plus maze test for anxiolytics was higher than in the other two tests. Efficacies of all the four test agents in all the three tests increased with increasing number of days of oral treatments. Results of these pilot experiments should be helpful for more rational selections of pharmacologically interesting dose ranges and treatment regimens of fumarates and Fumaria indica extracts for further more holistic explorations of their diverse therapeutic potentials.

Rare Thoracolumbar Facet Synovial Cyst Presenting as Paraparesis

Anshul Dahuja,Gitanshu Dahuja,Rashmeet Kaur 대한척추신경외과학회 2015 Neurospine Vol.12 No.3

Spinal cord compressing syndrome due to synovial cyst (SC) of the thoracolumbar spine is a rare clinical condition. In this report we aim to heighten awareness of the thoracolumbar facet synovial cyst as a possible cause of thoracic myelopathy. The SC was removed thoroughly by laminectomy. The patient had an excellent recovery. The etiological and therapeutic aspects are discussed.

Anti-diabetic effects of blue honeyberry on high-fed-diet-induced type II diabetic mouse

Anshul Sharma,Joo Wan Kim,Sae Kwang KU,Jae-Suk Choi,Hae-Jeung Lee 한국영양학회 2019 Nutrition Research and Practice Vol.13 No.5

BACKGROUND/OBJECTIVE: The blue honeysuckle berry (Lonicera caerulea var. edulis L.) is a small deciduous shrub belonging to the Caprifoliaceae family that is native to Russia, China, Japan, and Korea. The berry of this shrub is edible, sweet and juicy and is commonly known as the blue honeyberry (BHB). This study examined the anti-diabetic potential of BHB on high-fat-diet-induced mild diabetic mice. The hypoglycemic, and nephroprotective effects of the 12-week oral administration of blue honeyberry extract were analyzed. MATERIALS/METHODS: The hypoglycemic effects were based on the observed changes in insulin, blood glucose, and glycated hemoglobin (HbA1c). Furthermore, the changes in the weight of the pancreas, including its histopathology and immunohistochemical investigation were also performed. Moreover, the nephroprotective effects were analyzed by observing the changes in kidney weight, its histopathology, blood urea nitrogen (BUN), and serum creatinine levels. RESULTS: The results showed that the high-fat diet (HFD)-induced control mice showed a noticeable increase in blood glucose, insulin, HbA1c, BUN, and creatinine levels. Furthermore, growth was observed in lipid droplet deposition related to the degenerative lesions in the vacuolated renal tubules with the evident enlargement and hyperplasia of the pancreatic islets. In addition, in the endocrine pancreas, there was an increase in the insulin-and glucagon-producing cells, as well as in the insulin/glucagon cell ratios. On the other hand, compared to the HFD-treated mice group, all these diabetic and related complications were ameliorated significantly in a dose-dependent manner after 84 days of the continuous oral administration of BHBe at 400, 200 and 100 mg/kg, and a dramatic resettlement in the hepatic glucose-regulating enzyme activities was observed. CONCLUSIONS: By assessing the key parameters for T2DM, the present study showed that the BHBe could act as a potential herbal agent to cure diabetes (type II) and associated ailments in HFD-induced mice.

Analysis of Leuconostoc citreum strains using multilocus sequence typing

Anshul Sharma,Jasmine Kaur,이설희,박영서 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.6

The objective of this study was to perform genetic diversity analysis of 13 strains isolated from South Korean foods by multilocus sequence typing (MLST). For typing, seven housekeeping loci (atpA, dnaA, dnaK, gyrB, pheS, pyrG, and rpoA) were selected, amplified and analyzed. Fifty-one polymorphic sites varying from 1 to 22 in each species were identified. Thirteen sequence types were generated with allele numbers ranged from 2 to 10. The overall relationship between strains was assessed by unweighted pair group method with arithmetic mean dendrogram and minimum spanning tree. In addition, combined spits tree analysis revealed intragenic recombination. No clear relationship was observed between the isolation sources and strains. The developed MLST scheme enhanced our knowledge of the population diversity of Leu. citreum strains and will be used further for the selection of industrially important strain.

HEDEA: A Python Tool for Extracting and Analysing Semi-structured Information from Medical Records

Anshul Aggarwal,Sunita Garhwal,Ajay Kumar 대한의료정보학회 2018 Healthcare Informatics Research Vol.24 No.2

Objectives: One of the most important functions for a medical practitioner while treating a patient is to study the patient’s complete medical history by going through all records, from test results to doctor’s notes. With the increasing use of technology in medicine, these records are mostly digital, alleviating the problem of looking through a stack of papers, which are easily misplaced, but some of these are in an unstructured form. Large parts of clinical reports are in written text form and are tedious to use directly without appropriate pre-processing. In medical research, such health records may be a good, convenient source of medical data; however, lack of structure means that the data is unfit for statistical evaluation. In this paper, we introduce a system to extract, store, retrieve, and analyse information from health records, with a focus on the Indian healthcare scene. Methods: A Python-based tool, Healthcare Data Extraction and Analysis (HEDEA), has been designed to extract structured information from various medical records using a regular expression-based approach. Results: The HEDEA system is working, covering a large set of formats, to extract and analyse health information. Conclusions: This tool can be used to generate analysis report and charts using the central database. This information is only provided after prior approval has been received from the patient for medical research purposes.

Molecular typing tools for identifying and characterizing lactic acid bacteria: a review

Anshul Sharma,이설희,박영서 한국식품과학회 2020 Food Science and Biotechnology Vol.29 No.10

Identification and classification of beneficialmicrobes is of the highest significance in food science andrelated industries. Conventional phenotypic approachespose many challenges, and they may misidentify a target,limiting their use. Genotyping tools show comparativelybetter prospects, and they are widely used for distinguishingmicroorganisms. The techniques already employed ingenotyping of lactic acid bacteria (LAB) are slightly differentfrom one another, and each tool has its ownadvantages and disadvantages. This review paper compilesthe comprehensive details of several fingerprinting toolsthat have been used for identifying and characterizing LABat the species, sub-species, and strain levels. Notably, mostof these approaches are based on restriction digestion,amplification using polymerase chain reaction, andsequencing. Nowadays, DNA sequencing technologieshave made considerable progress in terms of cost,throughput, and methodology. A research journey todevelop improved versions of generally applicable andeconomically viable tools for fingerprinting analysis isongoing globally.

Tracking of deliberately inoculated Leuconostoc mesenteroides and Lactobacillus brevis in kimchi

Anshul Sharma,Jasmine Kaur,이설희,박영서 한국식품과학회 2020 Food Science and Biotechnology Vol.29 No.6

The objective of this study was to track intentionallyinoculated Leuconostoc mesenteroides (11251) andLactobacillus brevis (B151) strains in kimchi using randomamplified polymorphic DNA (RAPD), repetitive elementpalindromic PCR (rep-PCR), and comparative housekeepinggene sequences analysis. The 16S rRNA gene providedspecies-level information for 30 colonies randomly pickedfrom kimchi inoculated with strains 11251 and B151. Outof 30 colonies, one colony was matched to strain 11251,and two colonies were found identical to strain B151 referencestrain in inoculated kimchi. Notably, among thethree tools, strain 11251 was best tracked by comparativegene sequence analysis, while strain B151 tracked by allthree tools. Our results suggest that the gene sequenceanalysis is a more reliable tool for tracking of desiredstrains than RAPD and rep-PCR. Based on the findings, itis recommended that gene sequence analysis could be usedto avoid misuse of industrially useful strains within thegrowing food industry.

Lithium ion Battery Parameter extraction using the Physics Based Mathematical model and Neural Network method

Anshul Nagar,Jonghoon Kim 전력전자학회 2023 전력전자학술대회 논문집 Vol.2023 No.7