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Andre,Irma Isnafia Arief,Astari Apriantini,Anuraga Jayanegara,Cahyo Budiman 한국축산식품학회 2022 한국축산식품학회지 Vol.42 No.1
This study aimed to evaluate the effectiveness of propolis extract as a natural preservative for livestock products in term of chemical and microbiological characteristics by meta-analysis. The stages carried out in this study were identification;selection;checking suitability;and the resulting selected articles were used in the meta-analysis. The selection results obtained a total of 22 selected journal articles consisting of 9 articles for analysis of the antimicrobial activity of propolis extract and 13 articles for analysis of the chemical and mirobiological characteristics of livestock products. The articles were obtained from electronic databases;namely Science Direct and Google Scholar. The model used in this study is the random-effect model involving two groups;control and experimental. Heterogeneity and effect size values were carried out in this study using Hedge’s obtained through openMEE software. Forest plot tests and data validation on publication bias was obtained using Kendall’s test throught JASP 0.14.1 software. The results showed that there is a significant relationship between propolis extract with the results of the antimicrobial activity (p<0.05). In addition;the results of the application of propolis extract on the livestock products for the test microbes and the value of thiobarbituric acid reactive substances (TBARs) showed significant results (p<0.05). Conclusion based on the random-effect model on the effectiveness of antimicrobial activity of propolis extract and their apllication as a natural preservative of the chemical and microbiological characteristics of livestock products is valid by Kendall’s test (p>0.05). Propolis in this case effectively used as natural preservatives in livestock products.
Andre,Irma Isnafia Arief,Astari Apriantini,Anuraga Jayanegara,Cahyo Budiman 한국축산식품학회 2022 한국축산식품학회지 Vol.42 No.2
This study aimed to evaluate the effectiveness of propolis extract as a natural preservative for livestock products in term of chemical and microbiological characteristics by meta-analysis. The stages carried out in this study were identification, selection, checking suitability, and the resulting selected articles were used in the meta-analysis. The selection results obtained a total of 22 selected journal articles consisting of 9 articles for analysis of the antimicrobial activity of propolis extract and 13 articles for analysis of the chemical and mirobiological characteristics of livestock products. The articles were obtained from electronic databases, namely Science Direct and Google Scholar. The model used in this study is the random-effect model involving two groups, control and experimental. Heterogeneity and effect size values were carried out in this study using Hedge’s obtained through openMEE software. Forest plot tests and data validation on publication bias was obtained using Kendall’s test throught JASP 0.14.1 software. The results showed that there is a significant relationship between propolis extract with the results of the antimicrobial activity (p<0.05). In addition, the results of the application of propolis extract on the livestock products for the test microbes and the value of thiobarbituric acid reactive substances (TBARs) showed significant results (p<0.05). Conclusion based on the random-effect model on the effectiveness of antimicrobial activity of propolis extract and their apllication as a natural preservative of the chemical and microbiological characteristics of livestock products is valid by Kendall’s test (p>0.05). Propolis in this case effectively used as natural preservatives in livestock products.
Andre´ Luiz A. Pizzolatti,Florian Gaudig,Daniel Seitz,Carlos R. M. Roesler,Gean Vitor Salmoria 한국조직공학과 재생의학회 2018 조직공학과 재생의학 Vol.15 No.6
BACKGROUND: Glucosamine hydrochloride (GlcNHCl) has been shown to inhibit cell growth and matrix synthesis, but not with N-acetyl-glucosamine (GlcNAc) supplementation. This effect might be related to an inhibition of critical growth factors (GF), or to a different metabolization of the two glucosamine derivatives. The aim of the present study was to evaluate the synergy between GlcNHCl, GlcNAc, and GF on proliferation and cartilage matrix synthesis. METHOD: Bovine chondrocytes were cultivated in monolayers for 48 h and in three-dimensional (3D) chitosan scaffolds for 30 days in perfusion bioreactors. Serum-free (SF) medium was supplemented with either growth factors (GF) TGF-b (5 ng mL-1) and IGF-I (10 ng mL-1), GlcNHCl or GlcNAc at 1mM each or both. Six groups were compared according to medium supplementation: (a) SF control; (b) SF ? GlcNHCl; (c) SF ? GlcNAc; (d) SF ? GF; (e) SF ? GF ? GlcNHCl; and (f) SF ? GF ? GlcNAc. Cell proliferation, proteoglycan, collagen I (COL1), and collagen II (COL2) synthesis were evaluated. RESULTS: The two glucosamines showed opposite effects in monolayer culture: GlcNHCl significantly reduced proliferation and GlcNAc significantly augmented cellular metabolism. In the 30 days 3D culture, the GlcNHCl added to GF stimulated cell proliferation more than when compared to GF only, but the proteoglycan synthesis was smaller than GF. However, GlcNAc added to GF improved the cell proliferation and proteoglycan synthesis more than when compared to GF and GF/GlcNHCl. The synthesis of COL1 and COL2 was observed in all groups containing GF. CONCLUSION: GlcNHCl and GlcNAc increased cell growth and stimulated COL2 synthesis in long-time 3D culture. However, only GlcNAc added to GF improved proteoglycan synthesis.
Rediscovering an Analogue Heritage
Andre Gencalves(안드레 곤살베스) 한국전자음악협회 2011 에밀레 Vol.9 No.1
디지털 신시사이저의 출현 이래로 아날로그 세대의 구식의 제어 방식은 이제 새로운 기술의 발전에 힘입어 새롭게 융합된 방식을 보이고 있다. 이러한 방법은 아날로그와 디지털 두 가지 방식에 있어서 모두 최상의 결과를 보여 준다. 이 글을 통해 필자는 과거 전압 제어 컴퓨터 계열 장비들의 가장 최근의 개발 상황을 소개하고자 한다. 이러한 새로운 패러다임은 내장형 컴퓨팅의 스펙트럼에 속하는 하드웨어를 기반으로 하고 있으며, 표준 전통 방식의 전압제어 신시사이저와 호환된다. 필자의 연구와 상업적 전압제어 신시사이저 모듈의 개발에 근거하여, 어떻게 전압 제어 컴퓨터를 뛰어 넘을 것인지, 그리고 하드웨어와 소프트웨어에 모두 적용되는 또 다른 실행 방법을 개발할 수 있을지에 초점을 맞추고자 한다. 아울러 이 글에 설명된 모듈은 전압 제어 신시사이저의 사용을 위한 새롭고 강력한 도구를 만들어낸다. With this paper I intend to report the latest developments in what was previously defined as The Voltage-Controlled Computer(VCC)[1]. This new paradigm is a hardware based system locating itself in a specific spectrum of Embedded Computing tat also complies to the standards and tradition of the Voltage-Controlled Synthesizer(VCS) as in[2][3][4]. This solution allows it’s users to rethink and setup new models for analog and digital integration and interaction within a Modular Synthesizer system. A report on the latest hardware developments and a full description of it’s actual software library illustrates how the VCS can be augmented through this particular device. Based on my own research and development of commercial VCS Modules, emphasis is directed towards developments beyond the VCC and the different implementation methods used for both software and hardware. Described modules bring new and powerful tools to the use of the Voltage-Controlled Synthesizer and are now in use by hundreds of user’s all over the world.
Comparative Study on the Optimization Methods for a Motor Drive of Artificial Hearts
Andre Pohlmann,Marc Leßmann,Kay Hameyer 대한전기학회 2012 Journal of Electrical Engineering & Technology Vol.7 No.2
Worldwide cardiovascular diseases are the major cause of death. Aside from heart transplants, which are limited due to the availability of human donor hearts, artificial hearts are the only therapy available for terminal heart diseases. For various reasons, a total implantable artificial heart is desirable. But the limited space in the human thorax sets rigorous restrictions on the weight and dimensions of the device. Nevertheless, the appropriate functionality of the artificial heart must be ensured and blood damage must be prevented. These requirements set further restrictions to the drive of this device. In the this paper, two optimization methods, namely, the manual parameter variation and Differential Evolution algorithm, are presented and applied to match the specifications of an artificial heart.