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      • KCI등재

        THE GROUP OF STRONG GALOIS OBJECTS ASSOCIATED TO A COCOMMUTATIVE HOPF QUASIGROUP

        Jose N. Alonso ´Alvarez,Ramon Gonz´alez Rodr´ıguez,Jose M. Fern´andez Vilaboa 대한수학회 2017 대한수학회지 Vol.54 No.2

        Let $H$ be a cocommutative faithfully flat Hopf quasigroup in a strict symmetricmonoidal category with equalizers. In this paper we introduce the notion of (strong) Galois $H$-object and we prove that the set of isomorphism classes of (strong) Galois $H$-objects is a (group) monoid which coincides, in the Hopf algebra setting, with the Galois group of $H$-Galois objects introduced by Chase and Sweedler.

      • KCI등재

        Prognostic role of genetic biomarkers in clinical progression of prostate cancer

        Maria Jesus Alvarez-Cubero,Luis Javier Martinez-Gonzalez,Maria Saiz,Pedro Carmona-Saez,Juan Carlos Alvarez,Manrique Pascual-Geler,Jose Antonio Lorente,Jose Manuel Cozar 생화학분자생물학회 2015 Experimental and molecular medicine Vol.47 No.-

        The aim of this study was to analyze the use of 12 single-nucleotide polymorphisms in genes ELAC2, RNASEL and MSR1 as biomarkers for prostate cancer (PCa) detection and progression, as well as perform a genetic classification of high-risk patients. A cohort of 451 men (235 patients and 216 controls) was studied. We calculated means of regression analysis using clinical values (stage, prostate-specific antigen, Gleason score and progression) in patients and controls at the basal stage and after a follow-up of 72 months. Significantly different allele frequencies between patients and controls were observed for rs1904577 and rs918 (MSR1 gene) and for rs17552022 and rs5030739 (ELAC2). We found evidence of increased risk for PCa in rs486907 and rs2127565 in variants AA and CC, respectively. In addition, rs627928 (TT–GT), rs486907 (AG) and rs3747531 (CG–CC) were associated with low tumor aggressiveness. Some had a weak linkage, such as rs1904577 and rs2127565, rs4792311 and rs17552022, and rs1904577 and rs918. Our study provides the proof-of-principle that some of the genetic variants (such as rs486907, rs627928 and rs2127565) in genes RNASEL, MSR1 and ELAC2 can be used as predictors of aggressiveness and progression of PCa. In the future, clinical use of these biomarkers, in combination with current ones, could potentially reduce the rate of unnecessary biopsies and specific treatments.

      • KCI등재

        Bioremediation Potential of a Tropical Soil Contaminated with a Mixture of Crude Oil and Production Water

        Alvarez, Vanessa Marques,Santos, Silvia Cristina Cunha dos,Casella, Renata da Costa,Vitae, RonaIt Leite,Sebastin, Gina Vazquez,Seldin, Lucy The Korean Society for Microbiology and Biotechnol 2008 Journal of microbiology and biotechnology Vol.18 No.12

        A typical tropical soil from the northeast of Brazil, where an important terrestrial oil field is located, was accidentally contaminated with a mixture of oil and saline production water. To study the bioremediation potential in this area, molecular methods based on PCR-DGGE were used to determine the diversity of the bacterial communities in bulk and in contaminated soils. Bacterial fingerprints revealed that the bacterial communities were affected by the presence of the mixture of oil and production water, and different profiles were observed when the contaminated soils were compared with the control. Halotolerant strains capable of degrading crude oil were also isolated from enrichment cultures obtained from the contaminated soil samples. Twenty-two strains showing these features were characterized genetically by amplified ribosomal DNA restriction analysis (ARDRA) and phenotypically by their colonial morphology and tolerance to high NaCl concentrations. Fifteen ARDRA groups were formed. Selected strains were analyzed by 16S rDNA sequencing, and Actinobacteria was identified as the main group found. Strains were also tested for their growth capability in the presence of different oil derivatives (hexane, dodecane, hexadecane, diesel, gasoline, toluene, naphthalene, o-xylene, and p-xylene) and different degradation profiles were observed. PCR products were obtained from 12 of the 15 ARDRA representatives when they were screened for the presence of the alkane hydroxylase gene (alkB). Members of the genera Rhodococcus and Gordonia were identified as predominant in the soil studied. These genera are usually implicated in oil degradation processes and, as such, the potential for bioremediation in this area can be considered as feasible.

      • KCI등재후보

        Ultra Wideband Channel Model for Indoor Environments

        Alvarez, Alvaro,Valera, Gustavo,Manuel Lobeira,Torres, Rafael-Pedro,Garcia, Jose-Luis The Korea Institute of Information and Commucation 2003 Journal of communications and networks Vol.5 No.4

        This paper presents an in-depth study of a UWB indoor radio channel between 1 and 9 GHz, which was used for the subsequent development of a new statistical UWB multipath channel model, focusing on short range indoor scenarios. The channel sounding process was carried out covering different indoor environments, such as laboratories, halls or corridors. A combination of new and traditional parameters has been used to accurately model the channel impulse response in order to perform a precise temporal estimation of the received pulse shape. This model is designed specifically for UWB digital systems, where the received pulse is correlated with an estimated replica of itself. The precision of the model has been verified through the comparison with measured data from equivalent scenarios and cases, and highly satisfactory results were obtained.

      • Manufacture of Al<sub>2</sub>O<sub>3</sub>/Ti composite by aluminum bonding reaction for their use as a biomaterial

        Alvarez-Carrizal, Ruth P.,Rodriguez-Garcia, Jose A.,Cortes-Hernandez, Dora A.,Esparza-Vazquez, Sergio J.,Rocha-Rangel, Enrique Techno-Press 2021 Advances in materials research Vol.10 No.4

        This research shows the development of a composite material with an alumina matrix reinforced with different percentages of titanium (0.0%, 0.5%, 1%, 2% y 3%) with the intention of analyzing their mechanical and biocompatible properties for its possible application as a biomaterial. Alumina was synthesized using the reaction bonding aluminum oxide (RBAO) methodology. The powders resulting from the milling process had a size distribution ranging from nanometers to 2 microns. By means of X-ray diffraction and differential thermal analysis, it was determined that aluminum oxidizes in both solid and liquid states. It was also found that the alumina formation reaction is complete at 900℃. Using scanning electron microscopy, it was determined that the microstructure has fine grain sizes and homogeneous morphology. Likewise, the elastic modulus and fracture toughness of the composites obtained were determined, results indicate that these properties are higher than the properties of cortical bone. In addition, bioactivity was promoted using the biomimetic method. The results obtained demonstrate that the resulting composite can be used as a biomaterial.

      • KCI등재

        Exploring the Key Design Attributes of Cafés from User-Generated Contents

        Alvarez, Gabriela,민아람 한국실내디자인학회 2022 한국실내디자인학회논문집 Vol.31 No.6

        In the last couple of decades, the use of social media has consistently increased. Different social media platforms allow users to interact and create diverse types of content, making them able to share their opinions. With brands getting involved in these platforms, it is important to know how their image is portrayed by their customers on social media. This includes the café industry. The purpose of our study is twofold. One is to understand which design attributes make a café appealing to social media users, and another is to examine whether the Google Cloud Vision API is able to differentiate the key design attributes using user-generated content, which are Instagram posts in this research. In order to achieve these aims, we conducted a comparative case study using two cafés of unique interior designs located in Yeonnam-dong in Seoul, South Korea. Specifically, Greem Cafe and Perception Coffee were used. Using these cases as hashtags, we scraped the posts using a Python web scraper and screened out the posts irrelevant to the cafés. After, we ran them through the Google Cloud Vision API to obtain the labels and screened out the labels irrelevant to the interior designs, such as people and amenities. Finally, we were able to categorize the label to different design attributes and compare and contrast the labels from two cafés. The main differences shown in the results from the labels are that Greem Café had Color and Cartoon attribute labels like “Black-and-White” and “Drawing” that clearly represent the cartoonish interior design style. On the other hand, Perception Coffee’s most frequent label, “Wood” along with other labels like “Aeolian Landform” identify their wooden ceiling design. With these results, it is shown that the Google Cloud Vision API is able to distinguish the main design elements from both cafés. This research utilizes a new tool that can be useful for future researchers and designers that deal with big data, also this research brings insight for designers at the time of creating new places by

      • SCIESCOPUSKCI등재

        Effect of implant- and occlusal load location on stress distribution in Locator attachments of mandibular overdenture. A finite element study

        Alvarez-Arenal, Angel,Gonzalez-Gonzalez, Ignacio,deLlanos-Lanchares, Hector,Martin-Fernandez, Elena,Brizuela-Velasco, Aritza,Ellacuria-Echebarria, Joseba The Korean Academy of Prosthodonitics 2017 The Journal of Advanced Prosthodontics Vol.9 No.5

        PURPOSE. The aim of this study is to evaluate and compare the stress distribution in Locator attachments in mandibular two-implant overdentures according to implant locations and different loading conditions. MATERIALS AND METHODS. Four three-dimensional finite element models were created, simulating two osseointegrated implants in the mandible to support two Locator attachments and an overdenture. The models simulated an overdenture with implants located in the position of the level of lateral incisors, canines, second premolars, and crossed implant. A 150 N vertical unilateral and bilateral load was applied at different locations and 40 N was also applied when combined with anterior load at the midline. Data for von Mises stresses in the abutment (matrix) of the attachment and the plastic insert (patrix) of the attachment were produced numerically, color-coded, and compared between the models for attachments and loading conditions. RESULTS. Regardless of the load, the greatest stress values were recorded in the overdenture attachments with implants at lateral incisor locations. In all models and load conditions, the attachment abutment (matrix) withstood a much greater stress than the insert plastic (patrix). Regardless of the model, when a unilateral load was applied, the load side Locator attachments recorded a much higher stress compared to the contralateral side. However, with load bilateral posterior alone or combined at midline load, the stress distribution was more symmetrical. The stress is distributed primarily in the occlusal and lateral surface of the insert plastic patrix and threadless area of the abutment (matrix). CONCLUSION. The overdenture model with lateral incisor level implants is the worst design in terms of biomechanical environment for the attachment components. The bilateral load in general favors a more uniform stress distribution in both attachments compared to a much greater stress registered with unilateral load in the load side attachments. Regardless of the implant positions and the occlusal load application site, the stress transferred to the insert plastic is much lower than that registered in the abutment.

      • SCIESCOPUSKCI등재

        The Effect of Ginseng on Muscle Injury and Inflammation

        Alvarez, A.I.,De Oliveira, A.C. Cabral,Perez, A.C.,Vila, L.,Ferrando, A.,Prieto, J.G. The Korean Society of Ginseng 2004 Journal of Ginseng Research Vol.28 No.1

        The effect of Panax ginseng administration in muscle inflammatory process induced after eccentric exercise, that causes myofibrillar disruption, was studied. Changes in lipid peroxidation, inflammation, glycogen levels in muscle and release of myocellular proteins to blood were measured. The analyses were performed immediately after eccentric exercise and over week since this period are necessary for the muscle damage-repair cycle. The ginseng extract (100 mg kg$^{-1}$ ) was orally administered to rats for three months, before the eccentric exercise performance. The results showed the protective role of ginseng against skeletal muscle damage. This effect could be associated with their membrane stabilising capacity since creatine kinase (CK) activity was significantly decreased 96 h post-exercise from 523$\pm$70 to 381$\pm$53 and 120 h post-exercise from 443$\pm$85 to 327$\pm$75 in treated animals. $\beta$-glucuronidase activity, as indicator of inflammation, showed a significant reduction of about 15-25% in soleus, vastus and triceps in these post-exercise times. The lipid peroxidation, measured by malondyaldehyde levels, was significantly decreased in the 24 h post-exercise period in soleus and vastus intermedius muscles and on the recovery period. Finally ginseng administration reduced significantly the decrease of the glycogen levels immediately after exercise and when the regenerative process took place (72-168 h post exercise). Collectively, the results have showed that ginseng did not inhibit the vital inflammatory response process associated with the muscle damage-repair cycle but presumably ameliorate the injury.

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