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- 저자 : Alptug (검색결과 3 건)
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Prolonged Tp-e Interval, Tp-e/QT Ratio and Tp-e/QTc Ratio in Patients with Type 2 Diabetes Mellitus
Alptug Tokatli,Fethi Kiliçaslan,Metin Alis,Omer Yiginer,Mehmet Uzun 대한내분비학회 2016 Endocrinology and metabolism Vol.31 No.1
Background: Type 2 diabetes mellitus (T2DM) is associated with increased risk of malignant ventricular arrhythmias. Cardiac electrical inhomogeneity may be the leading cause of the increased arrhythmic risk in patients with T2DM. The peak and the end of the T wave (Tp-e) interval and associated Tp-e/QT ratio are promising measures of ventricular repolarization indicating transmural dispersion of repolarization. The aim of this study was to assess ventricular repolarization in patients with T2DM by using Tp-e interval, Tp-e/QT ratio and Tp-e/corrected QT interval (QTc) ratio. Methods: Forty-three patients with T2DM and 43 healthy control subjects, matched by gender and age, were studied. All participants underwent electrocardiography (ECG) recording. PR, RR and QT intervals represents the ECG intervals. These are not abbreviations. In all literature these ECG intervals are written like in this text. Tp-e intervals were measured from 12-lead ECG. Rate QTc was calculated by using the Bazett’s formula. Tp-e/QT ratio and Tp-e/QTc ratio were also calculated. Results: Mean Tp-e interval was significantly prolonged in patients with T2DM compared to controls (79.4± 10.3, 66.4± 8.1 ms, respectively; P<0.001). We also found significantly higher values of Tp-e/QT ratio and Tp-e/QTc ratio in patients with diabetes than controls (0.21± 0.03, 0.17± 0.02 and 0.19± 0.02, 0.16± 0.02, respectively; P<0.001). There was no difference in terms of the other ECG parameters between the groups. Conclusion: Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio were prolonged in patients with T2DM. We concluded that T2DM leads to augmentation of transmural dispersion of repolarization suggesting increased risk for ventricular arrhythmogenesis.
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Alptug Unal,Mevlut Yasar Kaltakci 국제구조공학회 2016 Steel and Composite Structures, An International J Vol.21 No.4
There are many studies in the literature conducted on the subject of ensuring earthquake safety of reinforced concrete and steel structures using steel braced frames, but no detailed study concerning individual behavior of steel braced frames under earthquake loads and strengthening of reinforced concrete structures with out-of-plane steel braced frames has been encountered. In this study, in order to evaluate behaviors of "Concentrically Steel Braced Frames" types defined in TEC-2007 under lateral loads, dimensional analysis of Concentrically Steel Braced Frames designed with different scales and dimensions was conducted, the results were controlled according to TEC-2007, and after conducting static pushover analysis, behavior and load capacity of the Concentrically Steel Braced Frames and hinges sequence of the elements constituting the Concentrically Steel Braced Frames were tested. Concentrically Steel Braced Frames that were tested analytically consist of 2 storey and one bay, and are formed as two groups with the scales 1/2 and 1/3. In the study, Concentrically Steel Braced Frames described in TEC-2007 were designed, which are 7 types in total being non-braced, X-braced, V- braced, Λ- braced, \- braced, /- braced and K- braced. Furthermore, in order to verify accuracy of the analytic studies performed, the 1/2 scaled concentrically steel X-braced frame test element made up of box profiles and 1/3 scaled reinforced concrete frame with insufficient earthquake resistance were tested individually under lateral loads, and test results were compared with the results derived from analytic studies and interpreted. Similar results were obtained from both experimental studies and pushover analyses. According to pushover analysis results, load-carrying capacity of 1/3 scaled reinforced concrete frames increased up to 7,01 times as compared to the non-braced specimen upon strengthening. Results acquired from the study revealed that reinforced concrete buildings which have inadequate seismic capacity can be strengthened quickly, easily and economically by this method without evacuating them.
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Yucel, Haluk,Cobanbas, Ibrahim,Kolbasi, Asuman,Yuksel, Alptug Ozer,Kaya, Vildan Korean Nuclear Society 2016 Nuclear Engineering and Technology Vol.48 No.2
High-energy linear accelerators are increasingly used in the medical field. However, the unwanted photo-neutrons can also be contributed to the dose delivered to the patients during their treatments. In this study, neutron fluxes were measured in a solid water phantom placed at the isocenter 1-m distance from the head of an18-MV linac using the foil activation method. The produced activities were measured with a calibrated well-type Ge detector. From the measured fluxes, the total neutron fluence was found to be $(1.17{\pm}0.06){\times}10^7n/cm^2$ per Gy at the phantom surface in a $20{\times}20cm^2$ X-ray field size. The maximum photo-neutron dose was measured to be $0.67{\pm}0.04$ mSv/Gy at $d_{max}=5cm$ depth in the phantom at isocenter. The present results are compared with those obtained for different field sizes of $10{\times}10cm^2$, $15{\times}15cm^2$, and $20{\times}20cm^2$ from 10-, 15-, and 18-MV linacs. Additionally, ambient neutron dose equivalents were determined at different locations in the room and they were found to be negligibly low. The results indicate that the photo-neutron dose at the patient position is not a negligible fraction of the therapeutic photon dose. Thus, there is a need for reduction of the contaminated neutron dose by taking some additional measures, for instance, neutron absorbing-protective materials might be used as aprons during the treatment.
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