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      • KCI등재

        Evaluation of the storage-associated changes in the fatty acid profile of oat-based gluten-free cookies prepared with different fats

        Alina Culetu,Valentin Ionescu,Maria Cristina Todasca,Denisa Eglantina Duta 한국식품과학회 2020 Food Science and Biotechnology Vol.29 No.6

        This study was carried out to investigate storageassociatedchanges in the fatty acid profile (with GC and1H-NMR techniques) of oat-based gluten-free cookiesprepared with different fats: margarine (MAR), butter(BUT), lard (LAR), refined palm oil (RPO), refined palmoil with stearin (RPOS), and hydrogenated palm oil (HPO). GC analysis indicated that palmitic and stearic acid werethe predominant saturated fatty acids (SFAs), regardless ofthe type of fat used. cis-Oleic acid represented the majormonounsaturated fatty acid (MUFA), while cis-linoleicacid was the most abundant polyunsaturated fatty acid(PUFA). After 6 months of storage, a significant decreasingtrend in SFA concentration was observed for LAR andRPOS cookies, while a decrease in MUFA concentrationwas observed only for HPO cookies. In fresh cookies andin cookies stored for 6 months, the contents of SFA,MUFA, and PUFA determined by GC were positivelycorrelated with those determined by 1H-NMR (r[0.90).

      • KCI등재

        Distribution and genetic diversity of Feline calicivirus in Moscow metropolitan area

        Alina Komina,Nikita Krasnikov,Oksana Kucheruk,Elena Zhukova,Anton Yuzhakov,Alexey Gulyukin 대한수의학회 2022 Journal of Veterinary Science Vol.23 No.6

        Background: Feline calicivirus (FCV) is widespread throughout the world. An FCV infection is associated with conjunctivitis, rhinitis, and mouth ulcers that can lead to the animal’s death. Because vaccination is not always effective, it is necessary to monitor the infection regularly. Objectives: This study examined the FCV epizootic situation in the Moscow metropolitan area by conducting a molecular phylogenetic analysis of the virus isolates. Methods: Samples from 6213 animals were examined by a reverse transcription polymerase chain reaction. For phylogenetic analysis, 12 nucleotide sequences obtained from animal samples were selected. Sequencing was performed using the Sanger method. Phylogenetic analysis was conducted using the Maximum Likelihood method. Results: The FCV genome was detected in 1,596 (25.7%) samples out of 6,213. In 2018, calicivirus was detected in 18.9% of samples, 27.8% in 2019, 21.4% in 2020, and 32.6% in 2021. Phylogenetic analysis of the F ORF2 region and the ORF3 start region led to division into two FCV genogroups. Most of the isolates (8 out of 12) were close to the Chinese strains. On the other hand, there were isolates closely related to European and American strains. The isolates circulating in Moscow were not included in clusters with vaccine strains; their nucleotide similarity varied from 77% to 83%. Conclusions: This study revealed a high prevalence and genetic diversity of the FCV in Moscow. The epizootic situation remains stably tense because 24 viruses were detected in 25% of animals annually.

      • Poster Session : PS 0340 ; Epidemiology and Public Health : Epidemiology of Pneumococcal Community-Acquired Pneumonias in Different Age Groups on Data of the Far East of Russia

        ( Alina Martynova ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Despite of the gained results in diagnostics and treatment of community- acquired pneumonias (CAP) the pneumococcal infection remains one of the leadingproblems of the modern medicine. Also there are still some discussions in epidemiological peculiarities of pneumococcal CAP in different age groups. The aim was to defi ne role of S. pneumoniae in ethiology. Methods: Our patients with confirmed CAP (400 patients) were divided on 4 age groups of 1-5 years, 6-15 years, adults (18-54), aged adults (55Results: pneumococcus was the leading pathogen in all age groups, and it was the most frequent in 1-5 children (42%), 6-15 (30%), 18-54 (35%), >55 years (60%). In some cases it was defi ned in association with the Chlamydia pneumophilla, Mycoplasma pneumonia and Haemophilus infi uenzae. The resistance of pneumcoocci to macrolides was in all groups, and it was connected with the spread of the mefE and ermB determinants, and there were only 12 penicilline resistant strains. The isolates were distributed among four major serotypes: 23F, 14, 18C, 6B. MLST (30 isolates) showed the spread of sequence types 90, 189, 240 and some others. Conclusions: Pneumococci remains the leading pathogen causing CAP in all age groups, and the epidemiological surveillance with molecular epidemiology study should be the fi rst step for preventive measures and the spread of the pneumococcal vaccines (e. g. Prevnar) among population.

      • KCI등재후보
      • KCI등재

        Abscopal effect in the radio and immunotherapy

        Alina M. Pevzner,Matvey M. Tsyganov,Marina K. Ibragimova,Nikolai V. Litvyakov 대한방사선종양학회 2021 Radiation Oncology Journal Vol.39 No.4

        This review is devoted to a rare in clinical practice, but promising phenomenon of regression distant non-irradiated metastases in combination therapy of cancer patients. R. H. Mole in 1953 suggested introducing the term “abscopal effect” to denote the effect of ionizing radiation “at a distance from the irradiated volume but within the same organism.” Currently, it is a hypothesis in the treatment of metastatic cancer, when there is a regression of untreated areas simultaneously with a decrease in the tumor. After the discovery of immune checkpoint cases were increase with patients treated with check-point blockade (especially lymphocyte associated protein 4, programmed cell death 1/programmed cell death 1 ligand 1) and which have an abscopal effect. This review systematizes works covering the time period from 1969 to 2019, which give cases of the abscopal effect at different localizations. However, abscopal effect is a poorly understood phenomenon. In this review, the authors tried to collect all information about the possible mechanisms of the abscopal effect, possible role in antitumor response and frequency abscopal effect at radio/immunotherapy or combined both.

      • KCI등재

        미·러 우주 항법체계 경쟁에 대한 러시아의 대응 : 복합지정학의 시각으로

        ( Alina Shymanska ) 한국세계지역학회 2020 世界地域硏究論叢 Vol.38 No.4

        본 논문의 목적은 위성항법체계를 놓고 러시아가 미국과 벌이고 있는 다층적인 위성항법체계 경쟁의 모습을 분석하는 데 있다. 위성항법체계는 러시아가 미국과 경쟁할 만한 역량을 보유하고 있는 분야 중 하나로, 러시아는 이를 단순한 기술적 이슈를 넘어 강대국 경쟁과 위신의 문제로 바라보고 있다. 러시아는 자국 위성항법체계인 GLONASS를 안보·사회·경제적 측면에서 매우 중요한 것으로 인식하고 있으며, 미국의 GPS에 대한 경쟁력을 상실하지 않고 나아가 더 우위에 설 수 있도록 하는 것을 전략적 목표로 삼고 있다. 우주, 지상관제 및 사용자의 세 부문에서 진행되고 있는 미국과 러시아 간의 위성항법체계 경쟁은 기술적 수준을 넘어서 국제정치의 층위에서도 나타나고 있다. 러시아는 위성 시스템 고도화 등 GLONASS의 우주 부문 발전을 추진하는 한편, 지상관제 네트워크 확장을 위해 동맹 정치를 활용하고 있다. 또한 보다 많은 사용자를 확보하여 경쟁력을 얻기 위해 러시아는 국내 법제를 정비하여 GLONASS 사용을 적극적으로 장려하고 있다. The satellite navigation system is one of the areas in which Russia has the capability to compete with the United States. This is not a simple technical issue, but also an issue of national competitiveness and prestige. As to the Russian Federation’s official documents, GLONASS is recognized as a system with high value in terms of Russian national security and socio-economic stability. The competition for satellite navigation systems between the US and Russia is a political competition beyond the frame of technology competition and appears in three sectors: space, ground control, and user sector. Along with the development in the space sector of GLONASS, such as the upgrading of the satellite system, Russia has focused on developing the ground control sector by using alliance politics to develop a network for the ground control. In the field of the user sector, Russia actively promotes the use of GLONASS in the country through legislation.

      • Search of Ways of Sustainable Development of Natural and Technical Systems on the Basis of Calculation of Operating Costs Taking into Account Geocryologic Division into Districts (on the Example of the Arctic site of the Northern Railroad)

        ( Alina Voytenko ) 대한지질공학회 2019 대한지질공학회 학술발표회논문집 Vol.2019 No.2

        Areas with dangerous processes which led to deformation of an embankment on a linear object laid in the conditions of the cryolithozone are study. The surveyed section of the railway route Pesets-Hanovey is located behind a polar circle (about 67.2 ° Northern Latitude, 63.5 ° East Longitude) in Bolshezemelskaya Tundra in the extreme northeast of the Komi Republic in the Vorkuta region. On the detailed site of a research the field educational practice on permafrostology which is carried out by Geological faculty MSU in the commonwealth with the Northern railroad Russian Railway. In the course which carried out a complex of field works: drilling operations, determination of Thermal-physics properties ground, definition of temperature condition of a surface, research of ground by an electric prospecting method, studying of temperature condition of permafrost, measurement of a layer of seasonal thawing, landscape micro zoning into districts of the site Hanovey, studying of frost blisters, determination of radiation balance, temperature condition of a brook, matching of results of geophysical researches, surface researches leveler. On the basis of monitoring, there were obtained data which formed the basis for development of a technique according to stability of development of a natural and technical system. The relation of size of the planned expenses to estimated size greatest possible can be used as an indicator of "security" of sustainable development. As cross-disciplinary approach to studying of a perspective is necessary, we developed offers of recommendatory character for socialists: geologists-permafrost researchers, engineers (designers and specialists in operation) and economists.

      • KCI등재후보

        Extended liver resection including hypertrophy concept with portal venous embolisation for giant haemangioma. Too much surgery?

        Alina Strohmaier,Kim C. Wagner,Tim Reese,Mohammad Fard-Aghaie,Georgios Makridis,York von Rittberg,Katja Horling,Karl J. Oldhafer 한국간담췌외과학회 2020 Annals of hepato-biliary-pancreatic surgery Vol.24 No.3

        Haemangiomas of the liver are benign tumours, which are often diagnosed randomly. With an increase in size haemangiomas could become symptomatic. In this case therapeutic options, surgical or interventional, have to be weighted to a conservative approach. We present a case of a 36-year old woman with a symptomatic giant haemangioma of the right liver lobe. Because of the size of the tumor and the small future liver remnant we decided to perform a major liver resection after hypertrophy induction with a preoperative portal vein embolization; an option mainly used for major hepatectomies in malignant tumors of the liver. But however, this case shows, that using a hypertrophy concept also for benign liver tumours is the safer approach, if an extended resection is necessary and the future liver remnant is critical.

      • KCI등재후보

        The Transformation of Asian Food Consumption and Russia as a Guarantor of Food Security in Asia

        ( Alina Shcherbakova ),( Denis Shcherbakov ) 서울대학교 통일평화연구원 2018 Asian Journal of Peacebuilding Vol.6 No.2

        This article examines the state of the global food problem, food security in East Asia, and the opportunity for Russia to prevent a food deficit in North Korea. The authors analyze the symptoms of the global food problem, the theoretical approaches to food security, the transformation of food consumption in Asia, and the food trade between Russia and the Korean Peninsula. One major conclusion is that Russia is in the best position among all countries to increase food exports to Asia―and especially to North Korea―as the people of Asia’s food consumption habits shape the new structure of food trade between that region and the rest of the world.

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