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( Ezgi Akyildiz Tezcan ),( Kemal Erol ),( Ilknur Albayrak Gezer ) 대한류마티스학회 2024 대한류마티스학회지 Vol.31 No.2
Piriformis syndrome is a neuromuscular disorder characterized by hip, buttock, and leg pain. Axial spondyloarthritis is a rheumatic disease primarily affecting the sacroiliac joint and the spine. Due to their anatomical proximity, the potential relationship between piriformis syndrome and sacroiliitis has been discussed for some time. However, literature review revealed that there is no study on piriformis syndrome in individuals with axial spondyloarthritis. Here, we present the case of a 30-year-old female with axial spondyloarthritis who developed severe low back, hip, and buttock pain that persisted despite initial treatment for axial spondyloarthritis. We first re-evaluated her condition through physical examination, magnetic resonance imaging, and an injection test for piriformis syndrome. Following a comprehensive assessment, the patient was diagnosed with both axial spondyloarthritis and piriformis syndrome. Subsequently, a tailored treatment plan was devised, addressing both conditions, and after a 3-month course of treatment, we obtained significant reduction in pain of the patient. This is the first case report in literature, where we used injection test to confirm the diagnosis of the piriformis syndrome in a patient with axial spondyloarthritis. We therefore strongly advocate considering piriformis syndrome as a potential etiology for pain in individuals with axial spondyloarthritis consistently. This recognition is important as piriformis syndrome does not respond adequately to non-steroidal antiinflammatory drugs and may lead to unnecessary use of biological disease-modifying antirheumatic drugs. Timely identification and intervention are imperative in ensuring optimal patient care.
Dielectrophoretic Behavior of Janus Particles with and without Biomolecule Conjugation
kubra akyildiz,이양우,이민지,박다인,구형준,최종훈,김교범 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.2
A typical definition of dielectrophoresis (DEP) is the transport phenomenon of translation of a polarizable particle in a non-uniform electric field. DEP allows for relatively convenient, versatile and efficient manipulation of particles in terms of sensitivity, selectivity and label-free properties. In this study, the polystyrene-based Janus Particles (JPs) consisting of two physicochemically different sides were prepared by the formation of particle monolayer and anisotropic metal deposition. DEP behaviors of JPs and biomolecule-conjugated JPs were investigated under various AC conditions, including voltages and frequencies. DEP behaviors of the JPs were monitored and compared, depending on the various biomolecule conjugation. Such experimental results of the current study could be applied for detection and separation of biomolecules.
Dielectrophoretic Behavior of Janus Particles and Biomolecule-Conjugated Janus Particles
Kubra Akyildiz,구형준,이민지,최종훈,김교범 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.1
Dielectrophoresis (DEP) can be defined as the transport phenomenon of polarizable particles under a non- uniform electric field. DEP can be used in the separation of particles with different physicochemical properties, as it is a versatile and efficient method that provides high selectivity. In our study, DEP behavior was observed in the varying AC conditions of the polystyrene-based Janus particles with and without bioconjugation. DEP behavior of these particles was monitored and compared depending on the biomolecule conjugation. Such experimental results of the current study could be applied for detection and separation of the specific biomolecules.
Kubra Akyildiz,Ji-Hye Kim,소주희,구형준 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.116 No.-
Gallium-based liquid metals are an attractive material for various applications, due to their excellent featuressuch as high electrical and thermal conductivity, low toxicity, and low viscosity with fluidic natureat room temperature. In particulate form, novel properties are endowed to the liquid metal, such as thecapabilities of shape transformation, plasmonic resonance and photothermal conversion. As a result,gallium-based liquid metal particles (GaLMPs) are of great importance in recent use for applications rangingfrom composites and electronics to biomedical applications. This review discusses the various preparationmethods of GaLMPs and their advantages and challenges. Up-to-date applications based on theGaLMPs are also introduced.
Halil I. Akyildiz,Busra Aydemir Yilmaz,Sumeyye Diler 한국섬유공학회 2022 Fibers and polymers Vol.23 No.10
Atomic layer deposition is a low-temperature conformal thin film formation technique that can modify materials tocreate functional surfaces. In this study, ALD coatings onto fibrous structures were used to synthesize the Ag nanoparticleson the fibers, which can be used for a wide variety of applications. During the treatment, cotton fibers were coated with20 nm thick ZnO films via ALD, and Ag nanoparticles were deposited on top using a photochemical approach. As thesamples were analyzed with FESEM images, the ZnO film coatings were found conformal and crystalline with evident grainson the fiber surfaces. After the photodeposition process, the Ag particles were also grown conformal on ALD films withflake-like morphology. XRD analysis showed ZnO and Ag crystalline peaks were visible for the corresponding samples. XPSanalysis showed Ag deposition onto untreated cotton is due to ionic interactions whereas the presence of ZnO enablesmetallic nanoparticles formation. Antibacterial activity of the coating materials was tested using ISO 20645 and AATCC 100standards, indicating that a high amount of silver present on the surface of the fibers created an uninhabitable environment forthe S. aureus and E. coli bacteria.
Tezcan Ezgi Akyildiz,Levendoglu Funda,Durmaz Mehmet Sedat,Kara Hasan,Batur Elif Balevi,Gezer Ilknur Albayrak,Korez Muslu Kazım 대한류마티스학회 2023 대한류마티스학회지 Vol.30 No.1
Objective: The aim of the present study is to assess carpal tunnel syndrome's (CTS’s) ultrasonography (US) and magnetic resonance imaging (MRI) findings in patients with psoriatic arthritis (PsA) and compare them with healthy controls. Methods: Thirty-nine PsA and twenty-eight healthy volunteers were examined in this study. Demographic and clinical features were recorded. CTS-6, a diagnostic algorithm, was used to estimate the probability of CTS. Electrodiagnostic study (EDS) was applied to all wrists included in the report, where the diagnosis of CTS was made by EDS. The cross-sectional area (CSA) of the median nerve was measured at pisiform bone level by US and MRI. Results: Regarding to the demographic characteristics, no statistically significant difference was found between the groups. Twelve of 39 (30.76%) PsA patients had CTS, whereas CTS was not detected in the control group (p=0.001). US and MRI showed increased median nerve CSA in PsA patients compared to healthy controls (p=0.005, p<0.001; respectively). Also, US and MRI showed increased median nerve CSA in CTS patients compared to others (p=0.002, p<0.001; respectively). The Pearson correlation coefficient between MRI and US measurements of the CSA was 0.85 (p<0.001). Conclusion: CTS frequency in PsA patients is found higher than healthy controls. The relationship between CTS diagnosed by EDS and CSA measured by both US and MRI was observed in PsA patients.
Pure Uterine Lipoma, a Very Rare Benign Tumor
Elif Ülker Akyildiz,Sema Ozuysal,Akgül Arici,Mehmet Aral Atalay 대한병리학회 2010 Journal of Pathology and Translational Medicine Vol.44 No.6
Pure lipomas of the uterus are very rare tumors that may be misdiagnosed on radiological examination due to their rarity and fat content. We present here the case of a 57-year-old postmenopausal woman who presented to the hospital with lower abdominal pain. Abdominal hysterectomy and bilateral salpingo-oophorectomy were performed under the prediagnoses of benign cystic ovarian teratoma or leiomyoma. On the histopathological examination of tissue samples, the tumor was composed of mature fat cells. There were a few smooth muscle cells confined to the periphery. Pure uterine lipoma may be asymptomatic or it may have symptoms similar to those of leiomyoma such as vaginal bleeding or pelvic pain. A pure lipoma should be diagnosed only if smooth muscle cells are confined to the periphery.