The Effects of Replacing Inorganic with a Lower Level of Organically Complexed Minerals (Cu, Zn and Mn) in Broiler Diets on Lipid Peroxidation and Antioxidant Defense Systems

Aksu, Devrim Saripinar,Aksu, Taylan,Ozsoy, Bulent,Baytok, Erol Asian Australasian Association of Animal Productio 2010 Animal Bioscience Vol.23 No.8

In this study, the effects of replacing inorganic copper, zinc and manganese with different levels of organic complexes of the same trace minerals on the lipid peroxidation and antioxidant defense systems in broilers were investigated. Two-hundred Ross-308 one-day-old broiler chickens were placed on controlled diets until 42 d of age. The experimental animals were divided into four groups comprising three experimental groups and one control group, each consisting of 50 chickens. All groups were also divided into five subgroups each containing 10 broiler chicks. The mineral content of the control group diet was controlled using a standard inorganic mineral premix with supplement levels and sources of trace minerals typical of commercial broiler diets according to the National Research Council (NRC) (containing 8 mg Cu as $CuSO_4$, 40 mg Zn as $ZnSO_4$, and 60 mg Mn as MnO, per kg). In the experimental diets, mineral premix was also comprised of inorganic formulations, except for those of Cu, Zn and Mn. Organically-complexed Cu, Zn, and Mn were separately added to the basal diet at 1/3 (L1), 2/3 (L2) and 3/3 (L3) levels with respect to the NRC recommendation, as Bioplex $Cu^{TM}$, Bioplex $Zn^{TM}$, Bioplex $Mn^{TM}$. At the end of the trial, the plasma Zn level significantly increased when the plasma Cu level significantly decreased (p<0.05) in chickens fed at 2/3 and 3/3 levels of organically complexed minerals. The liver trace mineral concentrations were significantly higher in chickens fed inorganic trace minerals in comparison to those fed organically-complexed minerals. The plasma malondialdehyde (MDA) level of experimental chickens was decreased in groups receiving levels of organic Cu, Zn and Mn in comparison to those fed inorganic forms (p<0.01). The erythrocyte superoxide dismutase (SOD) activity was higher in all groups receiving the organic mineral supplements in comparison to those fed inorganic forms (p<0.01). No differences were observed on either the erythrocyte catalase (CAT) activity or the plasma ceruloplasmin (Cp) levels, and the liver MDA levels and liver CAT and SOD activities in any of the groups that received the organic supplements of Cu, Zn, and Mn. It was concluded that supplementation of lower levels of organically-complexed copper, zinc, and manganese instead of their inorganic forms in diets had no negative effects on the antioxidant defense system in broilers.

AI-Based UX Assessment: The Role of GPT-4 Vision in UX/UI Comparison and Heuristic Evaluation

Aksu Emirhan(악수에밀한),Han Jieun(한지은) 한국HCI학회 2024 한국HCI학회 학술대회 Vol.2024 No.1

In exploring the role of AI in UX/UI evaluation, this study utilizes ChatGPT-4 Vision, to analyze five different Korean online retail platforms; Coupang.com Kurly.com SSG.com Lotteon.com and Homeplus.co.kr. By leveraging GPT-4 Vision’s integrated linguistic and visual capabilities, the study aims to synthesize and interpret UX/UI elements, assessing design standards and identifying areas for improvement. This approach provides a comprehensive view of each platforms UX/UI, revealing varying adherence to Nielsen’s usability heuristics and current design trends. The findings underscore the effectiveness of AI-assisted methodologies in conducting thorough UX/UI evaluations, highlighting AIs growing impact in the field of user experience research.

Evaluating Focal 18F-FDG Uptake in Thyroid Gland with Radiomics

Aksu Ayşegül,Karahan Şen Nazlı Pınar,Acar Emine,Çapa Kaya Gamze 대한핵의학회 2020 핵의학 분자영상 Vol.54 No.5

Purpose The aim of this study was to evaluate the ability of 18F-FDG PET/CT texture analysis to predict the exact pathological outcome of thyroid incidentalomas. Methods 18F-FDG PET/CT images between March 2010 and September 2018 were retrospectively reviewed in patients with focal 18F-FDG uptake in the thyroid gland and who underwent fine needle aspiration biopsy from this area. The focal uptake in the thyroid gland was drawn in 3D with 40% SUVmax threshold. Features were extracted from volume of interest (VOI) using the LIFEx package. The features obtained were compared in benign and malignant groups, and statistically significant variables were evaluated by receiver operating curve (ROC) analysis. The correlation between the variables with area under curve (AUC) value over 0.7 was examined; variables with correlation coefficient less than 0.6 were evaluated with machine learning algorithms. Results Sixty patients (70% train set, 30% test set) were included in the study. In univariate analysis, a statistically significant difference was observed in 6 conventional parameters, 5 first-, and 16 second-order features between benign and malignant groups in train set (p < 0.05). The feature with the highest benign-malignant discriminating power was GLRLMRLNU (AUC:0.827). AUC value of SUVmax was calculated as 0.758. GLRLMRLNU and SUVmax were evaluated to build a model to predict the exact pathology outcome. Random forest algorithm showed the best accuracy and AUC (78.6% and 0.849, respectively). Conclusion In the differentiation of benign-malignant thyroid incidentalomas, GLRLMRLNU and SUVmax combination may be more useful than SUVmax to predict the outcome.

Changes in the Physico-chemical and Microbial Quality during the Production of Pastırma Cured with Different Levels of Sodium Nitrite

Aksu, Muhammet Irfan,Erdemir, Ebru,Cakici, Neslihan Korean Society for Food Science of Animal Resource 2016 한국축산식품학회지 Vol.36 No.5

Pastırma, a dry-cured meat product, is produced from the whole muscle and/or muscles obtained from certain parts of beef and water buffalo carcasses. The purpose of this study was to determine the effects of different levels of sodium nitrite on changes in the physicochemical and microbial quality during the production of pastırma. The changes in residual nitrite, salt, pH, moisture, thiobarbutiric acid reactive substances (TBARS), colour (L*, a*, b*), total aerobic mesophilic bacteria (TAMB), lactic acid bacteria (LAB), Micrococcus/Staphylococcus (M/S), mould-yeast (M-Y), and Enterobacteriaceae counts of pastırma with 0, 50, 100 and 150 ppm sodium nitrite were determined during the production. The nitrite levels and the production stages had significant effects (p<0.01) on residual nitrite, TBARS, pH, salt, and colour values. The TBARS values of the pastırma with nitrite were significantly lower (p<0.05) than the control. The final TAMB, LAB, M/S, and M-Y counts of pastırma with 150 ppm nitrite were significantly (p<0.05) lower than the control. Also, the a* (relative redness) values of control pastırma were significantly lower (p<0.05) than the pastırma with nitrite. The production stages had a significant effect (p<0.01) on the moisture.

Nano and microsized EuB6 via magnesiothermic reduction

Mecit Aksu 한양대학교 세라믹연구소 2013 Journal of Ceramic Processing Research Vol.14 No.1

In this study, nano and micro sized EuB6 was synthesized via magnesiothermic reduction in open air. Method is optimized according to temperature and reaction time. Optimum temperature and reaction time are determined to be 600ο C and 4 hours. Products were analysed with x-ray diffraction (XRD), Scanning electron microscopy (SEM). XRD analysis proved formation of pure EuB6 and SEM analysis were used to characterize structure and morphologies of samples. Nanosized and microsized EuB6 with heterogeneous morpholgy was observed.

Changes in the Physico-chemical and Microbial Quality during the Production of Pastırma Cured with Different Levels of Sodium Nitrite

Muhammet Irfan Aksu,Ebru Erdemir,Neslihan Cakici 한국축산식품학회 2016 한국축산식품학회지 Vol.36 No.5

Pastırma, a dry-cured meat product, is produced from the whole muscle and/or muscles obtained from certain parts of beef and water buffalo carcasses. The purpose of this study was to determine the effects of different levels of sodium nitrite on changes in the physico-chemical and microbial quality during the production of pastırma. The changes in residual nitrite, salt, pH, moisture, thiobarbutiric acid reactive substances (TBARS), colour (L*, a*, b*), total aerobic mesophilic bacteria (TAMB), lactic acid bacteria (LAB), Micrococcus/ Staphylococcus (M/S), mould-yeast (M-Y), and Enterobacteriaceae counts of pastırma with 0, 50, 100 and 150 ppm sodium nitrite were determined during the production. The nitrite levels and the production stages had significant effects (p<0.01) on residual nitrite, TBARS, pH, salt, and colour values. The TBARS values of the pastırma with nitrite were significantly lower (p<0.05) than the control. The final TAMB, LAB, M/S, and M-Y counts of pastırma with 150 ppm nitrite were significantly (p<0.05) lower than the control. Also, the a* (relative redness) values of control pastırma were significantly lower (p<0.05) than the pastırma with nitrite. The production stages had a significant effect (p<0.01) on the moisture.

Thermostructural shape memory effect observations of ductile Cu-Al-Mn smart alloy

Canbay, Canan Aksu,Karaduman, Oktay,Ibrahim, Pshdar A.,Ozkul, İskender Techno-Press 2021 Advances in materials research Vol.10 No.1

The Cu-Al-Mn shape memory alloy (SMA) with a new different composition was fabricated by arc melting method. The characteristic shape memory effect (SME) property of Cu-Al based SMA was revealed by performing thermostructural measurements. The differential scanning calorimetry (DSC) tests were taken to observe the reversible martensitic phase transformation peaks of the alloy as evidence of SME property of the alloy. To determine the basic thermodynamical parameters of the alloy, these endothermic and exothermic transformation peaks were analyzed by the tangent differentiation method that was performed automatically by the DSC analyzing program over a manually selected part on the DSC curve and by these analyses the characteristic martensitic transformation temperatures (working temperatures) that found below 100℃ and the enthalpy change values of the alloy were directly obtained. The other kinetic transformation parameters of the alloy - the entropy change, hysteresis, and equilibrium temperature - were also determined. The common high-temperature behavior of the Cu-Al based Heusler alloys was detected by differential thermal analysis (DTA) measurement. The XRD and metallography tests that were conducted at room temperature showed the presence of M18R and the dominant 2H martensite structures that formed in the alloy and this dual martensitic structure was also prescribed by determining the theoretical e/a ratio of the alloy. Furthermore, the microhardness tests on the alloy demonstrated the high ductility feature of the alloy. All results demonstrated that the CuAlMn alloy exhibiting a shape memory effect property can be useful in smart alloy applications.

Changes in the Total Lipid, Neutral Lipid, Phospholipid and Fatty Acid Composition of Phospholipid Fractions during Pastırma Processing, a Dry-Cured Meat Product

Muhammet Irfan Aksu,Mehmet Dogan,Ahmet Necdet Sirkecioglu 한국축산식품학회 2017 한국축산식품학회지 Vol.37 No.1

Pastırma is a dry-cured meat product, produced from whole beef or water buffalo muscles. This study was carried out to investigate the effect of production stages (raw meat, after curing, after 2nd drying and pastırma) on the total lipid, neutral lipid, phospholipid and fatty acid composition of phospholipid fraction of pastırma produced from beef M. Longissimus dorsi muscles. The pH and colour (L*, a* and b*) analyses were also performed in raw meat and pastırma. It was found that pastırma production stages had significant effects (p

A rare case of shingles after COVID-19 vaccine: is it a possible adverse effect?

Saliha Buşra Aksu,Güzin Zeren Öztürk 대한백신학회 2021 Clinical and Experimental Vaccine Research Vol.10 No.2

Coronavirus disease 2019 (COVID-19) exhibit mild to moderate symptoms, whereas 15% of COVID-19 cases progress to pneumonia, some associated cutaneous findings are also reported as maculopapular eruptions, morbilliform rashes, urticaria, chickenpox-like lesions, and livedo reticularis. The inactivated COVID‐19 vaccines are authorized for use in some countries including Turkey. Here, we report an unusual case of varicella-zoster virus (VZV) reactivation in a 68-year-old male patient who was vaccinated against COVID-19. The patient presented to family medicine clinic with a stinging sensation and pain radiating from the right side of his chest to his back. Physical examination revealed multiple pinheaded vesicular lesions upon an erythematous base occupying an area on his right mammary region and back corresponding to T3–T5 dermatomes. He reported that he got his second dose of COVID-19 vaccine 5 days ago. As COVID 19 decreases the cell-mediated immunity, it could also increase the risk of herpes zoster (HZ). Although the exact reason remains unsolved, vaccine-induced immunomodulation caused by live attenuated vaccines and attenuated alloreactivity caused by inactivated vaccines may be responsible mechanisms for the reactivation of HZ. Epidemiological studies are needed to clarify the possible connection between vaccination and reactivation of herpesvirus infections.

International Transitional Administrations - Towards Territorialization of IGOs?

E?ref Aksu 서울대학교 국제학연구소 2006 Journal of International and Area Studies Vol.13 No.1

  While the "territorial state" has been amply scrutinized in International Relations (IR), the academic preoccupation with possible deterritorialization of governance seems to have overshadowed the importance of two parallel and equally remarkable possibilities: reterritorialization through intergovernmental organizations (IGOs) and territorialization of IGOs themselves. The gradual institutionalization of the practice of international transitional administration suggests itself as a potential manifestation of such parallel processes. While the most sophisticated scholarly argument about the nature of international administrations revolves around the question of state-building, this article contends that "state-building" is not all that the practice of transitional administration implies for contemporary global governance.