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Dimitrios G. Aggelis,Svetlana Verbruggen,Eleni Tsangouri,Tine Tysmans,Danny Van Hemelrijck 국제구조공학회 2016 Smart Structures and Systems, An International Jou Vol.17 No.1
One of the most commonly used techniques to strengthen steel reinforced concrete structures is the application of externally bonded patches in the form of carbon fiber reinforced polymers (CFRP) or recently, textile reinforced cements (TRC). These external patches undertake the tensile stress of bending constraining concrete cracking. Development of full-field inspection methodologies for fracture monitoring are important since the reinforcing layers are not transparent, hindering visual observation of the material condition underneath. In the present study acoustic emission (AE) and digital image correlation (DIC) are applied during four-point bending tests of large beams to follow the damage accumulation. AE helps to determine the onset of fracture as well as the different damage mechanisms through the registered shifts in AE rate, location of active sources and change in waveform parameters. The effect of wave propagation distance, which in large components and in-situ can well mask the original information as emitted by the fracture incidents is also discussed. Simultaneously, crucial information is supplied by DIC concerning the moments of stress release of the patches due to debonding, benchmarking the trends monitored by AE. From the point of view of mechanics, conclusions on the reinforcing contribution of the different repair methodologies are also drawn.
Konstantinos Lilimpakis,Aidona Tsepelaki,Electra Kalaitzopoulou,Dimitrios Zisimopoulos,Polyxeni Papadea,Marianna Skipitari,Athina Varemmenou,Apostolos Aggelis,Constantine Vagianos,Constantine Constant 한국실험동물학회 2022 Laboratory Animal Research Vol.38 No.4
Background: Obstructive jaundice induces oxidative changes in the brain parenchyma and plays significant role in clinical manifestations of hepatic encephalopathy. We aim to study the progression of the brain oxidative status over time and the differences of its pattern over the hemispheres, the brainstem and the cerebellum. We use an experimental model in rats and measuring the oxidative stress (OS) specific biomarkers protein malondialdehyde (PrMDA) and protein carbonyls (PrC = O). Results: Hyperbilirubinemia has been confirmed in all study groups as the result of common bile duct obstruction. We confirmed increase in both PrMDA and PrC = O biomarkers levels with different type of changes over time. We also confirmed that the oxidative process develops differently in each of the brain areas in study. Conclusions: The present study confirms the progressive increase in OS in all brain areas studied using markers indicative of cumulative protein modification.