Building a Domain-Specific French-Korean Lexicon

( Aesun Yoon ) 한국언어정보학회 2002 국제 워크샵 Vol.2002 No.-

Korean government has adopted the French TGV as a high-speed transportation system and the first service is scheduled at the end of 2003. TGV-relevant documents are consisted of huge volumes, of which over than 76% has been translated in English. A large part of the English version is, however, incomprehensible without referring to the original French version. The goal of this paper is to demonstrate how DiET 2.5, a lexicon builder, makes it possible to build with ease domain-specific terminology lexicon that may contain multimedia and multilingual data with multi-layered logical information. We believe our wok shows an important step in enlarging the language scope and the development of electronic lexica, and in providing the flexibility of defining any type of the DTD and the interconnectivity among collaborators. As an application of DiET 2.5, we would like to build a TGV-relevant lexicon in the near future.

Synthesis and Anticonvulsant Evaluation of N-Cbz-α-amino-N-alkoxysuccinimides

Aesun Byun,Minjeong Kim,Jongwon Choi,Kyung Ho Moon,Chung Kyu Lee,Minsoo Park 대한약학회 2004 Archives of Pharmacal Research Vol.27 No.3

In previous studies for the development of new anticonvulsants, we found that N-Cbz-a-amino- N-alkylsuccinimides exhibited significant anticonvulsant activities in the Maximal electroshock seizure (MES) and Pentylenetetrazole induced seizure (PTZ) tests, and also their anticonvulsant activities were dependent on the N-alkyl substituents existent in their structures. Based on these estimations, N-Cbz-a-amino-N-hydroxysuccinimide and various N-Cbz-a-amino-Nalkoxysuccinimides were prepared in order to develop more active anticonvulsants and to examine the effects of N-hydoxy or N-alkoxy groups on their anticonvulsant activities. The (R)- or (S)-N-Cbz-a-amino-N-hydroxysuccinimide and N-Cbz-a-amino-N-alkoxysuccinimides were prepared from the corresponding (R)- or (S)-N-Cbz-aspartic acid through the known synthetic procedures. Their anticonvulsant activities in the MES and PTZ test were evaluated. All of these compounds except 3a showed significant anticonvulsant activities against the PTZ test, but these compounds were not active in the MES test. The most active compound in the PTZ test was (R)-N-Cbz-a-amino-N-benzyloxysuccinimide (ED50=62.5 mg/kg). In addition, the anticonvulsant activities of these compounds were dependent on their N-substited groups. The order of anticonvulsant activity against the PTZ test , as judged from the ED50 values for (R) series was N-benzyloxy > N-hydroxy > N-isopropoxy > N-methoxy > N-ethoxy; for the (S) series N-ethoxy > N-benzyloxy > N-methoxy > N-isopropoxy.

Gastric Cancer Epidemiology in Korea

Aesun Shin,Jeongseon Kim,Sohee Park 대한위암학회 2011 Journal of gastric cancer Vol.11 No.3

Gastric cancer has been the most commonly diagnosed cancer in Korea although the age-standardized mortality and incidence has decreased gradually during last two decades. Helicobacter pylori infection and cigarette smoking are well-established risk factors, and the role of dietary factors, such as salted foods, fresh vegetables and fruits, soy foods, and processed or grilled meats on gastric carcinogenesis has been suggested. In this review, we review national and international gastric cancer statistics, studies on environmental risk factors conducted in the Korean population, and gastric cancer screening activities.

Synthesis and Hypnotic Activities of N-Cbz-α-aminoglutarimidooxy Carboxylate Derivatives

Aesun Byun,박진엽,문경희,박민수 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.7

Typical hypnotic drugs, such as barbitals and glutethimide, have a cyclic imide (-CO-NH-CO-) moiety. The N-Cbz-α-aminoglutarimidooxy carboxylate derivatives, which we previously showed exhibit moderate anticonvulsant activities, also have a cyclic imide (-CO-N-CO-) moiety. This structural similarity prompted us to examine the hypnotic activities of the N-Cbz-α-aminoglutarimidooxy carboxylate derivatives, and we describe their moderate hypnotic activities here.

A Network-Base Writing System for French

( Aesun Yoon ),( Hyuk Chul Kwon ) 한국언어정보학회 1995 국제 워크샵 Vol.1995 No.-

<Systeme Emi]e> is a French learning software program using network. This paper presents its implemented prototype version, Emile 1.1. It is based on the client/server model connected by a dial-up modem. The data structure, the tutoring tools and the user interface of Emile 1.1 are described in this paper. It mentions what should be added and improved in the next versions and further studies.

Synthesis and Anticonvulsant Activities of N-Cbz-α-aminoglutarimidooxy Carboxylate Derivatives

Aesun Byun,Jong Won Choi,Kyung Ho Moon,Chung Gyu Lee,Min Soo Park 대한약학회 2006 Archives of Pharmacal Research Vol.29 No.6

Previous studies on the anticonvulsant activity of N-Cbz-α-aminoglutarimides have shown that the derivatives of N-Cbz-α-amino-N-alkoxy glutarimide have significant anticonvulsant activity. In addition, their anticonvulsant activities are dependent on the presence of N-alkoxy groups. Based on these results, a series of N-Cbz-α-amino-glutarimidooxy carboxylates derivatives (3a-e) were synthesized in moderate yield using a known synthetic procedure. Their anticonvulsant activities were evaluated using the maximal electroshock seizure (MES) test, the pentylene tetrazole induced seizure (PTZ) test, and the strychinine (Str) threshold test with the ultimate aim of developing more active anticonvulsants. None of the compounds (3a-e) tested showed anticonvulsant activity in the MES and PTZ test. However, all the compounds tested exhibited significant anticonvulsant activity in the Str. test. The most active compound in the Str. test was the methyl ester of N-Cbz-α-amino-glutarimidooxy acetic acid 3a (ED50 = 42.9 mg/kg).

Une e´tude sur les termes d'adresse pour la traduction franc¸ais-core´en

YOON, Aesun 釜山大學校 1993 人文論叢 Vol.43 No.1

본 연구에서는 발화 상황을 (ⅰ) 공적(pubique)/사적(prive´e), (ⅱ) 직업관련 (professionnelle)/직업 무관(non-professionnelle), (ⅲ) 공식적 (offcielle)/비공식적 (non-of ficielle)로 분류하고 이에 따라 세 가지 범주의 호칭어를 분석의 대상으로 삼았다. 그 종류는 첫째, 개인을 사적인 상황에서 유일한 개체 (e^tre unique)로 파악하려는 성명 (anthroponymes), 둘째, 공적인 상황에서 사회적 체제의 서열화된 구성원으로 파악하려는 직함 (terms acve un ro^le public), 세째 가족이라는 특수한 체제 구성원으로 파악하려는 친족명 (terms de parente´)이다. 불어와 한국어에서 이 세 범주의 호칭어를 분석하여 두 언어 문화에서 변별적인 기능을 하는 의미-화용적인 구성 요소 (constituants semantico-pragmatiques)를 추출하였다. 이를 바탕으로 대화자 (interlocuteurs)를 상정하는 일반 텍스트를 한 언어에서 다른 언어로 번역 할 때 필요한 보완적 상황 정보 (informations sitionnelles supple´mentires)를 밝혀내고, 이를 두 한국어 소설의 불어 번역을 통해 검증하였다. 마지막으로 위의 분석을 토대로 호칭어 선택을 차트화하여 두 언어의 호칭어간의 등가관계 (rapport d'e´quivalonce)를 제시하였다.

Meat intake, heterocyclic amine exposure, and metabolizing enzyme polymorphisms in relation to colorectal polyp risk.

Shin, Aesun,Shrubsole, Martha J,Rice, Jeffrey M,Cai, Qiuyin,Doll, Mark A,Long, Jirong,Smalley, Walter E,Shyr, Yu,Sinha, Rashmi,Ness, Reid M,Hein, David W,Zheng, Wei American Association for Cancer Research 2008 Cancer Epidemiology, Biomarkers & Prevention Vol.17 No.2

<P>Most colorectal cancers arise from adenomatous polyps or certain hyperplastic polyps. Only a few studies have investigated potential genetic modifiers of the associations between meat intake and polyp risk, and results are inconsistent. Using data from the Tennessee Colorectal Polyp Study, a large colonoscopy-based study, including 1,002 polyp cases (557 adenoma only, 250 hyperplastic polyp only, 195 both polyps) and 1,493 polyp-free patients, we evaluated the association of colorectal polyp risk with carcinogen exposure from meat and genetic polymorphisms in enzymes involved in heterocyclic amine (HCA) metabolism, including N-acetyltransferase 1 (NAT1) and N-acetyltransferase 2 (NAT2), cytochrome P450 1A2 (CYP1A2), and aryl hydrocarbon receptor (AhR). Data on intake levels of meats by preparation methods, doneness preferences, and other lifestyle factors were obtained. Fourteen single nucleotide polymorphisms in the AhR, CYP1A2, NAT1, and NAT2 genes were evaluated. No clear association was found for any polymorphisms with polyp risk. However, apparent interactions were found for intake of meat and HCAs with AhR, NAT1, and NAT2 genotypes, and the interactions were statistically significant for the group with both adenomatous and hyperplastic polyps. Dose-response relationships with meat or HCA intake were found only among those with the AhR GA/AA (rs2066853) genotype, NAT1 rapid, or NAT2 rapid/intermediate acetylators but not among those with other genotypes of these genes. This dose-response relationship was more evident among those with both AhR GA/AA and the NAT1 rapid acetylator than those without this genotype combination. These results provide strong evidence for a modifying effect of metabolizing genes on the association of meat intake and HCA exposure with colorectal polyp risk.</P>

Trends of human papillomavirus-related head and neck cancers in Korea: national cancer registry data.

Shin, Aesun,Jung, Yuh-S,Jung, Kyu-Won,Kim, Kyeezu,Ryu, Junsun,Won, Young-Joo Triological Foundation [etc.] 2013 The Laryngoscope Vol.123 No.11

<P>The incidence of human papillomavirus (HPV)-positive head and neck cancers (HNCs) is increasing sharply worldwide, while their HPV-negative counterparts are showing a decreased frequency. However, epidemiologic data related to these changes are sparse in Korea, which is rapidly adopting more westernized lifestyles.</P>

전력반도체 패키지 공정에서의 Al wire bonding 공정

오애선(AeSun Oh),배현철(Hyun-Cheol Bae) 대한전자공학회 2017 대한전자공학회 학술대회 Vol.2017 No.6