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Clinical behaviour and outcome in pediatric glioblastoma: current scenario
Aditya Kumar Singla,Renu Madan,Kirti Gupta,Shikha Goyal,Narendra Kumar,Sushant Kumar Sahoo,Deepak K. Uppal,Chirag K. Ahuja 대한방사선종양학회 2021 Radiation Oncology Journal Vol.39 No.1
Pediatric glioblastoma (pGBM) is a rare entity accounting for only approximately 3% of all childhood brain tumors. Treatment guidelines for pGBM have been extrapolated from those in adult glioblastoma. Rarity of pGBM and underrepresentation of pediatric population in major studies precludes from defining the ideal treatment protocol for these patients. Maximum safe resection is performed in most of the cases followed by postoperative radiotherapy in children over 3 years of age. Benefit of temozolomide is unclear in these patients. Here, we present the clinicopathological details and outcome of six pGBM patients treated at our institute in 2018–2019.
Mental-Health and A.I. -A Paradigm of Human Mechanisation
( Aditya Nayak ) 중앙대학교 인문콘텐츠연구소 2020 인공지능인문학연구 Vol.6 No.-
This paper analyses the reconfiguration of the relationship between technological apparatus and our mental lifeworld. Technological network apparatus, particularly algorithmic networks are absorbing large domains of our life into themselves. In the process, our sense of self-identity has become fragile. We keep feeling disoriented by the overload of technological acceleration in our life in form of messages, notifications, and new methods of algorithmic monitoring of our life. Our sensory perception of reality has been hegemonised by intelligent machines. In response, the mental-health discourse identifies new mental-illnesses and their treatment procedures. However, the mental-health discourse functions on certain underlying philosophical assumptions which limit its ability to understand the contemporary real mental-problems faced by human beings. It gets trapped in its own logic. While claiming to bring the patient back into normality, it only traps humans further in the processes of human mechanisation. This paper highlights some of these issues and introspects new ways of understanding the current problem by going beyond the mental-health discourse.
A Highly-Integrated Analog Front-End IC for Medical Ultrasound Imaging Systems
Aditya Banuaji(아디탸 바누아지),Hyouk-Kyu Cha(차혁규) 대한전자공학회 2013 전자공학회논문지 Vol.50 No.12
초음파 의료 영상 응용 분야를 위한 고전압 고집적 아날로그 front-end 집적회로를 0.18-μm 표준 CMOS 반도체 공정을 이용하여 구현하였다. 제안 된 아날로그 front-end 집적회로는 2.6 MHz에서 15 Vp-p 전압까지 동작하는 트랜지스터 stacking 구조를 이용한 고전압 펄서와, 저전압에서 동작하는 저잡음 transimpedance 증폭기, 그리고 송신부와 수신부의 분리를 위한 고전압 차단 스위치로 구성되어 있다. 설계 된 집적회로는 0.15 mm<SUP>2</SUP> 이하의 작은 면적을 사용함으로써 휴대용 영상 시스템을 포함한 다중 어레이 초음파 의료 영상 시스템에 적용이 가능하다. A high-voltage highly-integrated analog front-end (AFE) IC for medical ultrasound imaging applications is implemented using standard 0.18-μm CMOS process. The proposed AFE IC is composed of a high-voltage (HV) pulser utilizing stacked transistors generating up to 15 Vp-p pulses at 2.6 MHz, a low-voltage low-noise transimpedance preamplifier, and a HV switch for isolation between the transmit and receive parts. The designed IC consumes less than 0.15 mm<SUP>2</SUP> of core area, making it feasible to be applied for multi-array medical ultrasound imaging systems, including portable handheld applications.
Aditya Shekhar,Lucia Beloqui Larumbe,Thiago Batista Soeiro,Yang Wu,Pavol Bauer 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5
There is an increasing focus on integrating flexible dc links for bulk power routing in medium voltage distribu-tion grids. In such applications, the ac-dc Modular Multilevel Converter (MMC) devised for medium voltage and high-power ratings can be an interesting choice. This paper highlights some less explored design trade-offs arising due to the limitation on N in relation to modulation frequency and arm inductance. Specifically, the study intends to describe the interdependent influence of each degree of freedom on several aspects such as capacitor voltage balancing, circulating currents and harmonic performance. Finally, the importance of considering interhar-monics in the performance assessment of the MMC instead of the conventional interpretation of distortion calculation is highlighted.
Aditya Narayan Shiv Shankar Swain,Suvankar Ganguly,Arunava Sengupta,Elanjickal Zachariah Chacko,Swapnil Dhakate,Pankaj Kumar Pandey 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.10
A coupled thermofluidic-mechanical model has been developed to analyse the thermomechanical state of the solidifying shellin a continuously cast steel billet. The computational fluid dynamics (CFD) based solver simulates the three-dimensionalflow field and solidification of molten steel as it flows inside the mould. Finite element method based thermomechanicalmodel is coupled with the CFD model to determine the resultant temperature distribution and stress–strain evolution in thesolidifying strand. The heat transfer at the mould-billet interface is taken into account by the calculation of heat flux using anovel inverse heat transfer algorithm. Temperature measurements made in the industrial billet mould have been used for thepurpose. Plant experiments and observations are correlated with the numerical results to provide quantitative understandingof the complex thermomechanical process during billet casting. Various parametric studies are also undertaken to examinethe effects of casting speed, superheat and heat flux changes on resultant strain and temperature distribution. It is observedthat the accumulated plastic strains exceed the critical strain at the off-corner region thereby indicating the possibility ofcrack formation in this region. Reduction of heat flux can lead to lowering of the strain rate at the corners and offer a viablesolution for reducing corner cracks.
The reliability of tablet computers in depicting maxillofacial radiographic landmarks
Aditya Tadinada,Mina Mahdian,Sonam Sheth,Taranpreet K Chandhoke,Aadarsh Gopalakrishna,Anitha Potluri,Sumit Yadav 대한영상치의학회 2015 Imaging Science in Dentistry Vol.45 No.3
Purpose: This study was performed to evaluate the reliability of the identification of anatomical landmarks in panoramic and lateral cephalometric radiographs on a standard medical grade picture archiving communication system (PACS) monitor and a tablet computer (iPad 5). Materials and Methods: A total of 1000 radiographs, including 500 panoramic and 500 lateral cephalometric radiographs, were retrieved from the de-identified dataset of the archive of the Section of Oral and Maxillofacial Radiology of the University Of Connecticut School Of Dental Medicine. Major radiographic anatomical landmarks were independently reviewed by two examiners on both displays. The examiners initially reviewed ten panoramic and ten lateral cephalometric radiographs using each imaging system, in order to verify interoperator agreement in landmark identification. The images were scored on a four-point scale reflecting the diagnostic image quality and exposure level of the images. Results: Statistical analysis showed no significant difference between the two displays regarding the visibility and clarity of the landmarks in either the panoramic or cephalometric radiographs. Conclusion: Tablet computers can reliably show anatomical landmarks in panoramic and lateral cephalometric radiographs.