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A Ghost-Valve Micropumping Paradigm for Biomedical Applications
Yasser Aboelkassem 대한의용생체공학회 2015 Biomedical Engineering Letters (BMEL) Vol.5 No.1
Purpose To present a novel micropumping “Ghost-Valve”principle that can be useful for many of biomedical applications. This pumping mechanism is inspired by microscale internalflow motions within insect tracheal networks, which is observedto be induced by localized rhythmic wall contractions. Methods A mathematical analysis based on the lubricationtheory is given to govern this internal flow motions and toderive expressions of velocity stream function, pressuredistributions, and net flow rate in a microchannel having twocontracting sites. Results The derived flow velocity stream function suggeststhat, there exist contraction-induced stagnation planes “Ghost-Valves” in the neighbourhoods of channel collapsing sites. The dynamics (locations, birth/death) of these ghost valveshave shown to be strong function of the assigned wall motionprotocol, which can be tuned to control flow transport alongthe axial direction and produce unidirectional net flow. Conclusions An inelastic microchannel subjected to azero pressure drop and undergoes localized rhythmic wallcontractions can work as a micropump. The minimumrequirement for this paradigm to produce a unidirectional netflow is; A channel with at least two contracting membranesthat move with a distinct time-lag with respect each other. The presented ghost-valve pumping model is expected tofunction efficiently in the low Reynolds number flowregime. Therefore, it yields a potential usefulness in many ofbiomedical microdevices for drug delivery, point-of-caretesting, and cardiac assistance devices.
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