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Agent Based Performance Analysis of Strategic Algorithms in Prisoner’s Dilemma
Aastha Yadav,Chandini Bhambhani,Pronay Peddiraju,Ronnie D. Caytiles,N.Ch. S.N. Iyengar 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.2
To create a system that provides a comparison of multiple algorithms that may be tested in the Prisoner’s Dilemma decision problem using two subjects in a dual agent environment. As an addition to understanding the effects of various algorithms and logic that helps influence a single agent’s decision, our system aims at analysing the performance of the same algorithms in iterative and multi agent systems. The results are obtained by using concepts of Swarm Intelligence, Multiple Agent Systems and Super Agents within the testing system. The results of the research are to expose the advantages and disadvantages of each schema to help plan investments, predict outcomes and for real world application of the Prisoner’s Dilemma in fields of Environmental Sciences, Psychology, Economics and many more such fields.
Aastha Kukreja,강병훈,김현욱,장은지,손혜영,허용민,함승주 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.48 No.-
Multifunctional nano-systems are an enticing approach toward the design of nanoparticles with desiredcharacteristics because of interactions between various components of the system. The combination ofvarious imaging modalities often augments the advantages and simultaneously overcomes restrictionsencountered by the individual techniques. This report describes the development of multifunctional goldcore/iron oxide porous-shell nanoparticles (AuFe NPs) functionalized with matrix metalloproteinasepeptide for targeted multi-mode magnetic resonance and computed tomography imaging. This studydemonstrates that AuFe NPs simultaneously possess both T2-based contrast effect and X-ray attenuationproperties in vitro. The drug loading capacity of porous iron oxide shell is also proposed.
( Aastha Shrestha ),( Nirmala Tilija Pun ),( Pil-hoon Park ) 한국응용약물학회 2018 Biomolecules & Therapeutics(구 응용약물학회지) Vol.26 No.5
Adiponectin, a hormone predominantly originated from adipose tissue, has exhibited potent anti-inflammatory properties. Accumulating evidence suggests that autophagy induction plays a crucial role in anti-inflammatory responses by adiponectin. However, underlying molecular mechanisms are still largely unknown. Association of Bcl-2 with Beclin-1, an autophagy activating protein, prevents autophagy induction. We have previously shown that adiponectin-induced autophagy activation is mediated through inhibition of interaction between Bcl-2 and Beclin-1. In the present study, we examined the molecular mechanisms by which adiponectin modulates association of Bcl-2 and Beclin-1 in macrophages. Herein, we demonstrated that globular adiponectin (gAcrp) induced increase in the expression of AUF1 and ZFP36L1, which act as mRNA destabilizing proteins, both in RAW 264.7 macrophages and primary peritoneal macrophages. In addition, gene silencing of AUF1 and ZFP36L1 caused restoration of decrease in Bcl-2 expression and Bcl-2 mRNA half-life by gAcrp, indicating crucial roles of AUF1 and ZFP36L1 induction in Bcl-2 mRNA destabilization by gAcrp. Moreover, knock-down of AUF1 and ZFP36L1 enhanced interaction of Bcl-2 with Beclin-1, and subsequently prevented gAcrp-induced autophagy activation, suggesting that AUF1 and ZFP36L1 induction mediates gAcrp-induced autophagy activation via Bcl-2 mRNA destabilization. Furthermore, suppressive effects of gAcrp on LPS-stimulated inflammatory mediators expression were prevented by gene silencing of AUF1 and ZFP36L1 in macrophages. Taken together, these results suggest that AUF1 and ZFP36L1 induction critically contributes to autophagy induction by gAcrp and are promising targets for anti-inflammatory responses by gAcrp.
Security, Vulnerability and Protection of Vehicular On-board Diagnostics
Aastha Yadav,Gaurav Bose,Radhika Bhange,Karan Kapoor,N.Ch.S.N Iyengar,Ronnie D. Caytiles 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.4
Recent studies have shown that ‘’hacktivists’’ can mount serious attacks on automobiles. The automotive On-Board Diagnostic (OBD) interface enables an efficient way to access information of the in-vehicle electronic system and leaves way for unauthorized access by an intruder. We discover that remote exploitation is feasible via a broad range of attack points such as mechanic tools, CD players, Bluetooth and Tire Pressure Monitoring System. Wireless communications channels allow long distance vehicle control. Finally, the paper discusses the drawbacks of Seed-Key Mechanism to authenticate and provide an extra layer of authentication to help build a safer automotive ecosystem.
BiFeO3-based Z scheme photocatalytic systems: Advances, mechanism, and applications
Aastha Dhawan,Anita Sudhaik,Pankaj Raizada,Sourbh Thakur,Tansir Ahamad,Pankaj Thakur,Pardeep Singh,Chaudhery Mustansar Hussain 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.117 No.-
Hitherto, heed has been paid substantially to concoct potential photocatalysts to counter the issues ofenvironmental degradation and energy crises. Amongst the plethora of photocatalysts, BiFeO3 (BFO)based photocatalysts are blooming as a centre of attraction due to fine chemical stability, and easy extraction. Also owing to a 2.2–2.8 electron volt (eV) narrow bandgap, BFO to has turned into a competent photocatalystfor efficient visible light absorption. So, keeping in mind the advantages of BFO and reviewingprevious reports, the present review offers a deep overview of conventional heterojunctions andadvanced Z-scheme heterojunctions. The main focus of the review is on BFO-based Z-scheme heterojunctionsalong with photocatalytic mechanisms and various applications. The successful construction ofBFO-based Z-scheme heterojunction eliminates drawbacks of bare BFO photocatalysts such as shortlivedcharge carriers, and high recombination rate, and also enhances light absorption of the system asa whole. Because of spatially separated oxidation and reduction sites and efficacious charge migration,BFO-based Z-scheme heterojunctions are proficient contenders among photocatalytic materials. Therefore, BFO-based Z-scheme heterojunctions are aptly used nowadays, in various fields like pollutantdegradation, wastewater treatment, organic synthesis, hydrogen production, and treatment ofantibiotics.
( Aastha Malik ),( Sarama Saha ),( Rajesh K Morya ),( Sanjay K Bhadada ),( Satya V Rana ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2021 Journal of Neurogastroenterology and Motility (JNM Vol.27 No.2
Background/Aims The pathogenesis of gastrointestinal (GI) symptoms in patients with type 2 diabetes mellitus (T2DM) is yet to be delineated clearly. Serotonin, a monoamine neurotransmitter, resides primarily in the gut and plays a vital role in GI system. However, no study has been documented the role of serotonin and serotonin transporter gene (SLC6A4) polymorphism in the development of GI symptoms in T2DM patients. Methods Three hundred diabetes patients attending diabetes clinic at Postgraduate Institute of Medical Education and Research, Chandigarh, and matched healthy controls were enrolled for this study. Plasma from collected blood sample was used for serotonin measurement by enzyme-linked immunosorbent assay method and buffy coat was used for isolation of DNA by phenol chloroform method. Serotonin transporter gene polymorphism was analyzed by polymerase chain reaction method. Results The frequency of short allele (S) and SS genotype was significantly higher in patients with T2DM than controls and was associated with increased risk of T2DM. The frequency of LS genotype showed an association with protection from the disease. Regarding GI symptoms, 78.2% of patients with constipation showed LL and LS genotypes, and 97.7% of patients with diarrhea had SS genotype. The patients without GI symptoms did not show any association of gut motility with genotype. Furthermore, serotonin was significantly higher in diabetic patients who belonged to SS genotype compared to LS or LL genotype and who presented with diarrhea. Conclusion SS genotypes are prone to develop diarrhea because of faster gut motility resulting from higher serotonin levels as compared to LS and LL genotype in T2DM patients. (J Neurogastroenterol Motil 2021;27:240-247)
Kukreja Aastha,Kang Byunghoon,Han Seungmin,Shin Moo-Kwang,손혜영,Choi Yuna,Lim Eun-Kyung,Huh Yong-Min,Haam Seungjoo 나노기술연구협의회 2020 Nano Convergence Vol.7 No.16
Manganese oxide (MnO) nanocubes were fabricated and their surface were modified by ligand encapsulation or ligand exchange, to render them water-soluble. And then, MnO formed the hollow structure by etching using acidic solution (phthalate buffer, pH 4.0). Depending on the ligand of the MnO surface, it increases the interaction between MnO and water molecules. Also, the hollow structure of MnO, as well as the ligand, can greatly enhance the acces‑ sibility of water molecules to metal ions by surface area-to-volume ratio. These factors provide high R1 relaxation, leading to strong T1 MRI signal. We have confirmed T1-weighted MR contrast effect using 4-kinds of MnO nanocubes (MnOEn, MnOEnHo, MnOEx and MnOExHo). They showed enough a MR contrast effect and biocompatibility. Espe‑ cially, among them, MnOExHo exhibited high T1 relaxivity (r1) (6.02 mM −1 s −1 ), even about 1.5 times higher sensitivity than commercial T1 MR contrast agents. In vitro/in vivo studies have shown that MnOExHo provides highly sensitive T1-weighted MR imaging, thereby improving diagnostic visibility at the disease site.