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김치 추출물에 의한 Aflatoxin B_1의 돌연변이 억제 효과
황승영,허영미,최영현,이숙희,박건영,이원호 부산대학교 유전공학연구소 1997 분자생물학 연구보 Vol.13 No.-
The inhibitory effects of Kimchi extracts on the mutagenicity induced by aflatoxin B₁(AFB₁) in Salmonella and Drosophila assay systems were studied. The kimchi extracts had inhibitory activity for His^+ to His^+ reverse-mutations induced by AFB₁acting on S. typhimurium TA98. A similar inhibitory effect was detected in somatic cell mutation assaying system of D. melanogaster. In Drosophila wing hair spot test, mutant clone frequency induced by AFB₁was consideranly inhibited by the kimchi extracts. These facts suggest that kimchi rxtracts can inhibit gene mutation, deletion, mititic chromosomal recombination and suppress the formation of cancer and mutation by DNA damage.
김치 추출물에 의한 Aflatoxin B_1의 돌연변이 억제 효과
이원호,이숙희,최영현,박건영,황승영,허영미 부산대학교 김치연구소 1997 김치의 과학과 기술 Vol.3 No.-
The inhibitory effects of kimchi extracts on the mutagenicity induced by aflatoxin B_1(AFB_1) in Salmonella and Drosophila assay systems were studied. The kimchi extracts had inhibitory activity for His to His^+ reverse-mutations induced by AFB_1 acting on S. typhimurium TA98. A similar inhibitory effect was detected in somatic cell mutation assaying system of D. melanogaster. In Drosophila wing hair spot test, mutant clone frequency induced by AFB_1 was considerably inhibited by the kimchi extracts. These facts suggest that kimchi extracts can inhibit gene mutation, deletion, mitotic chromosomal recombination and suppress the formation of cancer and mutation by DNA damage.