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      • KCI등재

        수영운동이 류마티스 관절염 모델 마우스의 혈청 염증지표 및 연골에서의 HIF-2α mRNA 발현에 미치는 영향

        지용석(Yong-Seok Ji),전정희(Joung-Hee Jon),윤진환(Jin-Hwan Yoon) 한국생활환경학회 2016 한국생활환경학회지 Vol.23 No.1

        The purpose of the present study was to investigate the effects of swimming exercise on serum inflammatory markers and HIF-2α mRNA expression of cartilage in rheumatoid arthritis model mice. Experiment animal were randomly assigned to swimming exercise group (n=9) and control group (n=9). Collagen-induced arthritis (CIA) was induced in male DBA/1J mice by intradermal injection of bovine collagen-II in Freund’s incomplete adjuvant (IFA). The swimming exercise group trained for 30 min/day, for 4 day/week for 6 weeks. Six weeks swimming exercise significantly reduced serum inflammatory makers (IL-6, TNF-α) and HIF-2α mRNA expression in cartilage while increasing the concentration of IL-10. Also, arthritic scores significantly reduced. Swimming exercise improved inflammatory response markers in mice with rheumatoid arthritis, suggesting that it can be a useful physical strategy in mice with rheumatoid arthritis. Future research should focus on finding optimal type and dose of exercise.

      • KCI등재

        태권도 몸통 돌려차기 동작에 대한 운동역학적 분석

        지용석(Yong Seok Ji),박인태(In Tae Park),강영석(Young Seok Kang) 한국사회체육학회 2008 한국사회체육학회지 Vol.0 No.34

        This Study has conducted an analysis on the Biomechanical Variables about Body-Dolyeochagi Motion of Taekwondo with the object of 5 superior players and the other 5 inferior players, among 10 persons of the lightweight-class college players, then obtained the conclusion as followings. The necessary time when carrying out Body-Dolyeochagi of Taekwondo was appeared as desirable to inflict a great impact to the target object within shorter time by increasing its pre-speed by means of making the articular angle of the knee to be bent quickly at the moment, and in case of the body pivot, at the moment when the right foot is removing from the ground, the inside-turning quickly of the right hip joint using the repulsive power of ground makes the situation of body pivot less, and it lets the knee joint bent rapidly where the moment arm is diminished, thence it was appeared as desirable to transmit the impulse which enables to attack the target object quickly. In order to transmit a great power to the target object by the hip joint angle, erect the body at the initial stage, keeping Long Axis Rotation widely, and it is also desirable to metastasize the momentum to the target object by means of winding the hip joint angle, and in case of the knee joint angle, the momental knee joint to be wound in maximum, by making the knee joint stretched greatly utilizing the Law of Action and Reaction at E3 time-point, it showed up as desirable to blow a great impact to the target object. Likewise, in case of the angle of foot articulation, when bending of the knee joint is maximized due to rapid extension of the foot articulation, it is desirable to beat accurately to the target object when impacting, and in the instance of External Oblique Muscle of Abdomen at Average Value of Integral Electromyogram for the principal muscle, owing to the rapid turning of the vertebrae at the moment of impact, its Antagonist was acted more, and in case of Erector Spinae Muscle, it is known that its body-trunk was quickly turned in the next motion of the superior players group. In case of Rectus Femoris and Biceps Femoris, the Bending and Extending Motion of the hip joint have been made more efficiently in the superior players group, and in Medial Gastrocnemius Muscle, the Bending and Extension of the knee joint were not efficient, and in case of Tibialis Anterior Muscle, since Plantar Flexion of the ankle joint was effectively established in the superior players group, it was appeared that an efficient impact thereat has been accomplished.

      • KCI등재
      • KCI등재

        무산소성 운동이 투기선수들의 근피로 및 혈중 염증반응 지표에 미치는 영향

        지용석(Yong Seok Ji) 한국사회체육학회 2011 한국사회체육학회지 Vol.0 No.45

        The purpose of this study was investigate to the effect of anaerobic exercise on V·O2max level, muscle fatique(CPK, LDH) and imflammatory makers(IL-6, CRP, TNF-α). The subject of this study were 28 people(4 groups; control, Wrestling, Taekwondo, and Judo athletes group). The data from this study were analyzed using One-way ANOVA and Repeated measures ANOVA. The following conclusions were obtained by comparing and analyzing the measurement value pre, post, and recovery of anaerobic exercise according to the combat training. First, the groups with combat training showed the higher enhancement than the control group(p<.001). Second, in the change of muscle fatigue and imflammatory makers, combat training groups were decreased recovery time more than control group(p<.001), Therefore, this study suggested that the makers of muscle fatique and imflammation could be enhanced by combat training.

      • KCI등재
      • KCI등재

        트레드밀 운동이 당뇨쥐 골격근 및 심근의 p-AMPK, p-ACC 및 Malonyl-CoA 발현에 미치는 영향

        조진경(Jin-Kyung Cho),지용석(Yong-Suk Ji),현광석(Kwang-Seok Hyun) 한국생활환경학회 2016 한국생활환경학회지 Vol.23 No.2

        This study was to investigated the effects of treadmill exercise on p-AMPK, p-ACC, and Malonyl-CoA expression of skeletal muscle and cardiac muscle in a streptozotocin (STZ)-induced diabetic rats. At 7 weeks of age, S.D rats (n=36) were induced diabetes by administering STZ. A STZ-induced rats were randomly assigned to a control (DM+C, n=12), moderate-intensity exercise group (DM+LE, n=12) and high-intensity exercise group (DM+HE, n=12). The rats were trained progressively on a treadmill, five days per weeks for eight weeks following treadmill running programs: moderate-intensity (15m/min for 60mins) and high-intensity (25m/min for 60mins). After 48-h of the last bout of exercise, blood and tissues of skeletal muscle and heart were harvested. Treadmill running for 8 weeks significantly reduced fasting glucose levels and HOMA-IR in diabetes rat models, regardless of exercise intensity. Both exercise groups significantly increased p-AMPK and p-ACC protein levels. Malonyl-CoA levels were significantly reduced in both exercise groups. The current findings suggest that treadmill running on a STZ-induced diabetes rats can provide an effective means to combat an insulin resistance and improve fatty-acid oxidation (i.e., p-AMPK, p- ACC and malonyl-CoA) in skeletal muscles and heart.

      • KCI등재

        수영운동이 난소절제 쥐 혈중 지질, 해마의 BDNF mRNA, c-fos mRNA 발현 및 공간기억에 미치는 영향

        조강희(Kang-Hee Jo),지용석(Yong Seok Ji),윤진환(Jin-Hwan Yoon) 한국생활환경학회 2021 한국생활환경학회지 Vol.28 No.4

        The purpose of this study was to investigate the effects of swimming exercise on serum Lipid, BDNF mRNA and c-fos mRNA expression of hippocampus and spatial memory in ovariectomized rats. Sixteen week old female rat(S.D) were randomly divided into three groups(n=12 in each group): the normal control group(CON), control group with ovariectomized(OVA+Con) and swimming exercise group with ovariectomized(OVA+SE). The exercise program consisted of a swimming exercise administered for 12 weeks. After 12 weeks of swimming exercise training, uterus weight was significantly induced in swimming exercise group compared with ovariectomized control group. serum total cholesterol, trigryceride, LDL-C level were significantly reduced in swimming exercise group compared with ovariectomized control group. However, HDL-C levels was non significantly induced in swimming exercise group compared with ovariectomized control group. BDNF, c-fos mRNA expression of hippocampus were significantly induced in swimming exercise group compared with ovariectomized control group. Spatial memory was significantly induced in swimming exercise group compared with ovariectomized control group. It is concluded that there is a protective role for swimming exercise in reducing the risk of cardiovascular desease in ovariectomized rats.

      • KCI등재

        안드로겐 결핍 쥐에서 운동 중재에 따른 시냅스 단백질의 발현 양상 규명

        백경아(Kyeong-A Baek),지용석(Yong Seok Ji),정수진(Sujeen Jung),윤진환(Jin-Hwan Yoon) 한국생활환경학회 2021 한국생활환경학회지 Vol.28 No.5

        The purpose of this experiment was to investigate the characterization of synaptic protein expression by exercise intervention in androgen-deficient rats. The experimental animals were divided into three groups (n=10 in each group): the normal control group (CON), orchiectomized(OCX+CON) and treadmill exercise group with orchiectomized(OCX+TE). The rats in the exercise group were forced to run on a treadmill for 30~45 min 5 times per week for 12 weeks. Compared to the CON group, the OCX+CON group showed significantly decreased serum testosterone levels and also, brain-derived neurotrophic factor (BDNF) and synapsin 1 (SYN1) mRNA expression in the hippocampus. Whereas, OCX+TE group was significantly increased testosterone and BDNF mRNA compared to the OCX+CON group. SYN1 mRNA was slightly increased than OCX+CON group, but was not significant different. These results suggest that exercise is one of the effective intervention strategies to prevent testosterone deficiency-mediated cognitive impairment the aging process of males.

      • KCI등재

        트레드밀 운동이 난소 절제 쥐의 지질대사 조절인자 및 지방조직 갈색화에 미치는 영향

        백경아(Kyeong-A Baek),지용석(Yong Seok Ji),윤진환(Jin-Hwan Yoon) 한국생활환경학회 2021 한국생활환경학회지 Vol.28 No.2

        The purpose of this study was to investigate the effects of aerobic exercise training on lipid metabolism regulators and browning of adipose tissue in ovariectomized rats. A total 36 of female Sprague-Dawley rats were divided into three groups: CON (normal control, n=12), OVA-CON (ovariectomized-control), OVA-TE (ovariectomized + treadmill exercise, n=12). The rats in the OVA-TE group were forced to run a treadmill for 30 min 4 times per week for 12 weeks. In the liver, the mRNA levels of peroxisome proliferator-activated receptor-gamma (PPARγ) and SPEBP-1 were significantly decreased in the OVA-TE group compared with the OVA-CON group (p<.05). In the gastrocnemius, the PGC-1α mRNA expression was significantly increased in the OVA-TE group compared to the OVACON group(p<.05). Also, the OVA-CON group showed significantly decreased UCP-1 mRNA levels compared to the CON group, while the OVA-TE group was significantly higher than the OVA-CON group(p<.05). These results indicate that regular aerobic exercise could improve the lipid metabolism-related factors and enhance the browning of adipose tissue in the ovariectomized rats.

      • KCI등재후보

        태권도 수련생의 수련특성이 도장만족도에 미치는 영향

        이종근(Jong Kun Lee),박인태(In Tae Park),지용석(Yong Seok Ji) 한국체육교육학회 2010 한국체육교육학회지 Vol.15 No.2

        본 연구는 태권도 수련생의 수련특성이 도장만족도에 미치는 영향을 규명하고, 태권도 수련생들의 수련특성을 파악하여 도장운영에 필요한 경영전략을 세우는데 필요한 기초자료를 제공하는데 그 목적이 있다. 연구대상은 2010년 현재 청주시에 위치한 대권도장을 이용하는 수련생 150명을 모집단으로 선정한 후 설문지를 배포하였고, 이 중 회수된 설문지는 141부였다. 분석결과 첫째, 성별 요인에서는 수련목적만이 유의한 차이가 있는 것으로 나타났고, 연령 요인에서는 수련시간, 수련기간, 수련목적 모두 유의한 차이가 있는 것으로 나타났다. 그리고 생활수준 요인에는 수련기간, 수련목적이 유의한 차이가 있는 것으로 나타났다. 둘째, 수련특성 하위요인 중 수련시간 요인에서는 도장만족도 하위요인 프로그램만족, 시설만족, 직원만족, 사회성만족 모두 긍정적인 영향을 미치지 않는 것으로 나타났고, 수련특성 하위요인 중 수련기간 요인에서는 도장만족도 하위요인 프로그램만족, 직원만족 요인이 유의한 영향을 미치는 것으로 나타났다. 그리고 수련특성 하위요인 중 수련목적 요인에서는 도장만족도 하위요인 프로그램만족 요인만이 유의한 영향을 미치는 것으로 나타났다. The goal of this study is looking for an effect how training characteristic of Taekwondo trainer have an influence on gymnasium satisfaction. The subject of study are trainers who are using the Taekwondo gymnasium located in Cheongju now in 2010 as population. Although we collected 150 by bias sampling of ramdom sampling, the last re-collected data was 148 and it was 98% higher return rate. Except for 7 among unreliable datum, 141 datum was used in the last analysis. It was 95.2% valid analysis rate. The methods of statistic analysis for dealing datum were verified by using frequency analysis, factorial analysis, Cronbach`s a test, one-way ANOVA, multiple regression analysis, and so on. In this way we got a result as follows. First, to verify differences between demographic characteristic and training characteristic, we conduct one-way ANOVA setting Taekwondo training characteristic as independent variable and vital statistical trait as dependent variable. As a result, we found that in sexual factor goal for training only has significant differences as p<.05 in significance level. In age factor, all of training time, training period and goal for training has significant differences as p<.001 in significance level. In living standard factor, training period as p<.01 and goal for training as p<.05. Second, to verify an effect how training characteristic of Taekwondo trainer have an influence on gymnasium satisfaction, we conducted multiple regression analysis. In training time factor among training characteristic subordinated factor, all of gymnasium, staff contentment and sociality contentment didn`t have a positive influence. In training period factor, program contentment factor have an influence on p<.001 and staff contentment do so p<.05 in significance level. And in goal for training factor, only program contentment factor do so p<.001 in significance level.

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