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      • SSCISCOPUSKCI등재

        Economic Valuation of Unpaid Work in Korea

        Kwon, Tae Hee Research Institute of Asian Women Sookmyung Women' 2005 Asian Women Vol.21 No.-

        The measurement of economic value on the unpaid work, corresponding to a household's non-market production, has been performed since 1920's through numerous studies. The field of studies is recently facing newfound attention and necessity to find a more appropriate method for measuring unpaid work. As the United Nation's recommendation for "A New System of National Accounts" redirected related studies to develop a satellite account that measures estimated value of unpaid work as a supplementary index to the household sector of the national accounts since the 1990s. In Korea, unpaid work by women was not measured because the Time Use Survey Data was not available. The purpose of this study is to estimate the value of the productive unpaid work-like housework, food preparation, household maintenance, cleaning, construction and repairs, shopping and services, household management, child care, adult care and volunteer services-performed by overall women in Korea based on the Time Use Survey Data of 1999 published at the National Statistics Office (NSO). The measurement methods used are individual function replacement cost method; generalist replacement cost method, gross opportunity cost method; net opportunity cost method, and integrated cost method. The results of this study show that the total share of women's unpaid work in the "Enlarged GDP" ranges between 21.8 and 27.7%, but the men's share ranges between 4.9 and 5.4%. This work identifies key components of a household's production in the Korean economy, and the estimation of non-market production facilitates comparative analysis with the relevant data of developed countries, and reexamines the contribution to the nation's economic growth made by women's unpaid work.

      • KCI등재

        융의 마음의 구조, 유형론과 이제마(李齊馬)의 지인론(知人論), 사상인(四象人)과의 비교 고찰

        김인태,고병희,송일병,Kim, In Tae,Ko, Byung-Hee,Song, Il-Byeong 사상체질의학회 1996 사상체질의학회지 Vol.8 No.2

        융과 동무(東武) 이제마(李濟馬)의 지인론(知人論)과 인간의 유형 연구의 비교를 통해 다음과 같은 결론을 얻을 수 있었다. 1. 융의 인간의 마음의 구조를 탐구한 작업이나 이제마(李濟馬)의 지인론(知人論)은 각각의 유형론(類型論)의 기본개념 설정에 중요 한 의미가 있다. 이들은 인간의 심성의 분석을 통하여 자신만의 독특한 유형론(類型論)을 개발해내었다. 2. 인식의 체계로서는 융은 의식, 개인적 무의식, 집단적 무의식, 자기의 사상론적(四象論的) 구조(構造)로, 이제마(李齊馬)는 사심신물(事心身物)의 사상론적(四象論的) 구조(構造)로서 인간을 설명하려 하였다. 그리고 유형론으로는 융은 사고형 감정형 감각형 직관형의 4개로, 이제마는 태양인(太陽人) 소양인(少陽人) 태음인(太陰人) 소음인(少陰人)의 4개로 나누었다. 공통적으로 사상론적(四象論的) 구조(構造)라는 점에 양자간의 유사성이 있다. 3. 융은 의식과 무의식을 탐구하였고 이제마(李濟馬)는 인의예지(仁義禮智)인 성(性)과 비박탐뢰(鄙薄貪賴)의 심욕(心慾)을 탐구하였는데 양자간에는 밀접한 관련이 있다고 사료된다. 또, 의식, 무의식과 군자의필(君子之心), 소인지필(小人之必)의 관련도 적용시킬 수 있다고 사료된다. 4. 이제마(李濟馬)의 대동(大同), 각립(各立), 행기지(行其知), 행기행(行其行)과 호선(好善), 악악(惡惡), 사심(邪心), 태행(怠行) 그리고 장부(臟腑)의 대소관계(大小關係)등은 융이 말한 제1기능(우월기능), 제2기능, 제3기능, 제4기능(열등기능)의 구분과 연관지어 생각해 볼 수 있다고 사료된다. 5. 융의 사고형 감정형 감각형 직관형의 4분류와 이제마(李濟馬)의 태양인(太陽人) 소양인(少陽人) 태음인(太陰人) 소음인(少陰人)과의 관계는 앞으로 많은 연구가 필요한 부분이라 생각된다. As considering a comparison study of the structure of mind and psychologic type of C.G Jung to Ji-In-Lon and Sa-Sang constituition of Lee Je Ma, I've got the following conclusion. 1. The study of the structure of mind of Jung and Ji-In-Lon of Lee Je ma have a important meaning to each theory of type of men. They developed their own peculiar theory of type men by the analysis of the mind of men. 2. Jung explained the organization of recognition by four phase theorical structure; consciousness, personal unconsciousness, collective unconsciousness, self. Lee Je Ma explained the organization of recognition by four phase theorical structure;Sa, Sim, Sin, Mul. And theory of type of men, Jung established four type; Tae-Yang-In, Tae-Um-In, So-Yang-In, So-Um-In, They all established the four phase structure, which have things in common. 3. Jung studied the consciousness and unconsciousness and Lee Je Ma studied the Sung-In, Eui, Ye, Ji, and Sim-Yock-Bi, Bak, Tam, Na. I think they have a close relationship. And I think there is relationship between consciousness, unconsciousness to Gun-Ja-Ji-Sim, So-In-Ji-Sim. 4. I think there is thought of relationship between Lee Je Ma's Dae-Dong, Gak-lip, Hang-gi-ji, Hang-gi-hang and Ho-sun, Oh-ak, Sa-sim, Tae-hang and relationship of internal organ's size to Jung's the first function, second function, third function, fourth function. 5. I think the relationship between the type of Jung;thinking type, feeling, type, sensation type, intuition type to the type of Lee Je Ma; Tae-Yang-In, Tae-Um-In, So-Yang-In, So-Yang-In, So-Um-In needs more study.

      • Proteomic Analysis of Thiol Specific‐Protein Oxidation

        Tae‐Hoon Lee,Hee‐Young Yang,Hoon‐In Choi,Gia‐Buu Tran,Ung Yang 한국동물생명공학회(구 한국동물번식학회) 2011 발생공학 국제심포지엄 및 학술대회 Vol.2011 No.1

        Peroxiredoxin II (Prdx II; a typical 2‐Cys Prdx) has been originally isolated from erythrocytes, and its structure and peroxidase activity have been adequately studied. Mice absent to Prdx II proteins had heinz bodies in their peripheral blood, and morphologically abnormal cells were detected in the dense red blood cell (RBC) fractions, which contained markedly higher levels of reactive oxygen species (ROS). In this study, a labeling experiment with the thiol‐modifying reagent biotinylated iodoacetamide (BIAM) in Prdx I‒/‒ mice revealed that a variety of RBC proteins were highly oxidized. To identify oxidation‐sensitive proteins in Prdx II‒/‒ mice, we performed RBC comparative proteome analysis in membrane and cytosolic fractions by nano‐UPLC‐MSE shotgun proteomics. We found oxidation‐sensitive 54 proteins from 61 peptides containing cysteine oxidation, and analyzed comparative expression pattern in healthy RBCs of Prdx II+/+ mice, healthy RBCs of Prdx II‒/‒ mice, and abnormal RBCs of Prdx II‒/‒ mice. These proteins belonged to cellular functions related with RBC lifespan maintain, such as cytoskeleton, stress‐induced proteins, metabolic enzymes, signal transduction, and transporters. Furthermore, protein networks among identified oxidation sensitive proteins were analyzed to associate with various diseases. Consequently, we expected that RBC proteome may provide clues to understand redox‐imbalanced diseases.

      • 의과대학과 한의과 대학의 통합교육과정 개발 가능성에 관한 연구

        Ohrr, Hee-Choul,Son, Tae-Yong 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

        Hee Choul Ohrr¹,Tae-Yong Son²¹Department of Preventive Medicine, Yonsei University College of Medicine, Seoul and ²Department of Medical Administration, Yuhan College, Buchun,Korea potential for integrated Medical School and Orental Medical School Currculum. Proceedings of International Symposium on East-West Medicine, Seoul. 82-89,1999.-This study was carried out to compare the educational contents between the western medical shcools and the oriental medical schools in Korea. The numbers of lectures, their credits, lecturing hours per week and the numbers of specific objectives were analyzed between the western and oriental medical schools. Formally published books from both western and oriental medical association, that is, the books of Specific Behavioral Objectives (SBOs)of both the western medical and the oriental medical parts are major source of data.Form numbers of lectures and their contents, we used the brochures on the lectures guidebooks. Three major western medical schools and the three major oriental medical schools, six schools in total were selected for comparison of education contents. The results are as Follows; 1 The oriental medical schools teach most lectures of western medical schools though the contents are a little different. 2.The western medical schools teach nothing about oriental medicine except only one school that teaches a smiple introductory course 3. The oriental medical schools teach as much as 43.4% of the SBOs of western Os of westrn medical school in number.Whereas the westerm medical schools theach 32.6% of the SBOs of oriental medical schools in number. 4.It is estimated that oriental medical schools can cover all the SBOs of western medical schools if they give lectures for one and a half year more. It is also estimated that western medical schools can cover all the SBOs of oriental medical school if they give lectures for two years more. It is highly recommendable that both western and oriental medical schools share lectures and give opportunity to take the both medical license examination if medical school students complete the requirement of the other medical part lectures. This could be a fundamental step to incorporate both the western and the oriental medicine in the future in Korea.

      • Targeting Multiple Myeloma Cell Death with Polyphenol EGCG

        Tae‐Hoon Lee,Hee‐Young Yang,Hoon‐In Choi,Ung Yang,Kyoung‐Jin Chung,Lina Ren 한국동물생명공학회(구 한국동물번식학회) 2011 발생공학 국제심포지엄 및 학술대회 Vol.2011 No.1

        (‐)‐Epigallocatechin 3‐gallate (EGCG) is a potent antioxidant polyphenol in green tea that acts as an anticancer agent via both direct and indirect pathways. Although the relationship between EGCG’s anticancer effects and its antioxidant activity is not fully understood, it is known that EGCG stimulates production of reactive oxygen species (ROS), which induce oxidative stress leading to cell death. In IM9 multiple myeloma cells, EGCG acted in a dose‐ and time‐dependent manner to induce apoptotic cell death. Among the antioxidant enzymes expressed in IM9 cells, levels of peroxiredoxin (Prdx) V were selectively and significantly reduced by EGCG. Moreover, the ROS scavenger NAC completely inhibited EGCG‐induced apoptosis and PrdxV reduction, while overexpression of PrdxV, but not a PrdxVC48S mutant, protected IM9 cells from EGCG‐induced apoptosis. EGCG‐induced reductions in cell viability and PrdxV levels were also observed in primary CD138+ multiple myeloma cells from patients. These results suggest that PrdxV is a key target via which EGCG mediates its anticancer effects.

      • Identification of Redox Sensitive Proteins in Prdx II Deficient Red Blood Cells

        Tae‐Hoon Lee,Hee‐Young Yang,Hoon‐In Choi,Gia‐Buu Tran,Ung Yang 한국동물생명공학회(구 한국동물번식학회) 2011 발생공학 국제심포지엄 및 학술대회 Vol.2011 No.1

        Red blood cells (RBCs) have been studied as models for infectious diseases, various symptoms of anemia, hemolysis, and erythrocyte aging. Although do not directly affect RBCs, other diseases may cause RBC physiological alterations that could be advanced for diagnostic aim or to convince better understanding of a certain pathological pattern. In this study, comparative RBC proteomics between healthy and abnormal conditions involve to promote aging related‐biomarker discovery. Peroxiredoxin II (Prdx II; a typical 2‐Cys Prdx) has been originally isolated from erythrocytes, and its structure and peroxidase activity have been adequately studied. Mice absent to Prdx II proteins had heinz bodies in their peripheral blood, and morphologically aged cells were detected in the dense RBC fractions, which contained markedly higher levels of reactive oxygen species (ROS). In addition, a labeling experiment with the thiol‐modifying reagent biotinylated iodoacetamide (BIAM) in Prdx II‒/‒ mice revealed that a variety of RBC proteins were highly oxidized. To identify oxidation‐sensitive proteins in Prdx II‒/‒ mice, we performed RBC comparative proteome analysis by nano‐UPLC‐MSE shotgun proteomics with relative protein quantitative analysis. We found oxidation‐sensitive 18 membrane and 41 cytosol proteins from 32 and 85 peptides containing cysteine oxidation, and analyzed comparative expression pattern in healthy RBCs of Prdx II+/+ mice (W1), healthy RBCs of Prdx II‒/‒ mice (K1), and abnormal RBCs of Prdx II‒/‒ mice (K2). These proteins belonged to cellular functions related with RBC lifespan maintain, such as cytoskeleton, stress‐induced proteins, amino acid/nucleic acid metabolic enzymes, signal transduction, and molecular transporters. Furthermore, protein networks among identified oxidation sensitive proteins were analyzed to associate with aging consequence. Consequently, we expected that RBC proteome may provide clues to understand redox‐imbalanced diseases.

      • KCI등재

        Study on Reliability Improvement of Voltage Transformers by Increasing Voltage Factor

        Tae‑Sik Kong,Hee‑Dong Kim,Hung‑Sok Park,Soo‑Hoh Lee,Soon‑Yong Kim,Pil‑Bum Joung,Jin‑Yeub Park 대한전기학회 2020 Journal of Electrical Engineering & Technology Vol.15 No.3

        Voltage transformers (VTs) must be highly reliable as they are essential components of the electric power industry. VT failures can cause a signifcant impact for important facilities such as nuclear power plants. In fact, VTs which passed the international standard, were damaged and sometimes resulted in the shutdown of the nuclear power plants. In order to improve the reliability, VTs with various iron core was studied. The electromagnetic feld simulation, a saturation characteristics test, and an overvoltage breakdown test were conducted. The result shows that the magnetic fux density signifcantly afects the reliability of VTs. To increase the reliability of VTs, it is required to reduce the magnetic fux density by increasing the knee-point and voltage factor. Owing to limited installation space, increasing the size of the iron core is difcult. Instead, VT by decreasing the thickness of the conductor and increasing the number of turns, it was possible to reduce the magnetic fux density without the size change. Therefore, improved VTs were obtained by decreasing the thickness of the conductor and increasing the number of turns, and the improved reliability was verifed through a comparison test with existing VTs. The fabricated VTs shows a signifcantly higher saturation voltage and breakdown time than existing VTs. Thus, by proposed VTs can contribute the stable operation of the nuclear power plant and improve the manufacturer’s quality.

      • Peroxiredoxin V Regulates Aco2, Acadm, and Acox1 Activity in Hypoxic Kidney

        Tae‐Hoon Lee,Hee‐Young Yang,Joseph Kwon,Hoon‐In Choi,Lina Ren,Ung Yang,Byung‐Ju Park,Zae Young Ryoo 한국동물생명공학회(구 한국동물번식학회) 2011 발생공학 국제심포지엄 및 학술대회 Vol.2011 No.1

        Peroxiredoxin V, an atypical thioredoxin peroxidase, is widely expressed in mammalian tissues. In addition, Prdx V is localized in mitochondria, peroxisome, cytosol, and nucleus. Prdx V has been reported to protect a wide range of cellular environments as antioxidant enzyme, and its dysfunctions may be implicated in several diseases, such as cancer, inflammation, and neurodegenerative disease. Identification and relative quantification of proteins affected by Prdx V may help identify novel signaling mechanisms that are important for oxidative stress response. However, the role of Prdx V in the modulation of hypoxia‐related cellular response is not studied yet. In order to examine the function of endogenous Prdx V in hypoxic condition in vivo, we generated a transgenic mouse model with Prdx V siRNA expression controlled by U6 promoter. Of many tissues, the knockdown of Prdx V expression was displayed in kidney, lung, and liver, but not spleen and skin. We conducted on the basis of nano‐UPLC‐MSE proteomic study to identify the Prdx V‐affected protein networks in hypoxic kidneys. In this study, we identified protein networks associated with oxidative stress, fatty acid metabolism, and mitochondrial dysfunction. Our results indicated that Prdx V affected to regulation of kidney homeostasis under hypoxia stress.

      • 말라리아 환자 32예의 임상적 고찰

        정용희,백일현,김태형,김영식,이우인,서환조 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.1

        목적 : 삼일열 말라리아는 국내에서 1986년 이후에는 박멸된 것으로 알려졌으나 1993년 이후 증가하는 양상을 보이고 있다. 이에 말라리아의 임상적 고찰을 통하여 이 질환을 이해함에 있다. 방법 : 1991년 1월부터 1999년 10월까지 반복적 고열과 오한을 주소로 본 병원에 내원하여 말초혈액 도말검사에 의해 말라리아 감염으로 확진된 32예의 환자에 대해서 후향적으로 조사하였다. 결과 : 1991년부터 1999년 10월까지 총 32명의 환자의 연도별 발생빈도는 각각 1991년에 1명, 1996년에 1명, 1997년에 3명, 1998년에 13명, 1999년에 14명이었다. 월별발생빈도는 7월과 8월에 집중적으로 발생하였다.(46.9%) 환자의 거주지는 경기 연천과 파주에 주로 분포되었다(53.1%). 성별발생분포는 32예의 환자중에 여자가 5명, 남자가 27명으로 남자가 더 많았다. 발병연령은 22세에서 87세까지 분포되었고 20-30대에 많이 발생하였으며 20대가 가장 많았다. 군인 및 제대자가 17명(59.4%)에 해당하였으며, 제대자의 평균 제대후의 기간은 10개월 정도였다. 가장 흔한 임상증상은 발열 및 오한이었다.(100%) 비장종대 및 간장종대는 각각 26명(81.3%), 3명(9.4%)에서 관찰되었다. 검사실 소견은 평균적으로 WBC 5.317/㎕, 혈색소 12.5±7.1g/㎗, 혈소판 78,906.3±68391.4㎕, GOT/GPT 43.7±26.7/49.6±57.3 IU/ℓ, Total bilirubin 1.6±0.9㎎/㎗를 보였다. 말초혈액 도말검사상 모두 P. vivax였다. 치료는 hydroxychloroquine과 primaquine의 치료에 잘 반응하였다. 결론 : 말라리아는 7월과 8월에 한국에서 호발하는 중요한 급성 열성 질환으로 조기 진단 및 치료에 보다 관심을 기울여야 할 것이다. Background : In Korea malaria has been rare, but since reemergence of indigenous vivax malaria in 1993, the number of cases of malaria have recently increased. We analyzed the cases of malaria who were treated in Kyung-Hee University College of Medicine with regard to define the clinical characteristics of malaria. Methods : We retrospectively analyzed of 32 cases of malaria admitted to Kyung-Hee University Hospital between 1991 and 1999. Malaria was diagnosed by peripheral blood smear. Results : Among a total of 32 cases, the number of yearly incidence of 1991, 1996. 1997, 1998 and 1999 were 1,1,3,13,14 respectively. It demonstrated the high incidence especially between July and August. The most patients (53.1%) resided in Yeonchon and Pajoo. Among them, 5 cases were female and 27 cases were male. The age distribution ranged from 22 to 76 year old. The high incidence of age was between 20's and 30's. Military solidiers and ex-soldiers are 17 cases(59.4 %). The most frequent symptom was fever and chills (100%). Splenomegaly and hepatomegaly were also observed in 81.3 %(26 of 32) and 9.4 %(3 of 32) respectively. The laboratory findings were WBC 5.317/㎕. Hb 12.5±2.1 g/dl. platelet 78,906±68,391.4/㎕. GOT/GPT 43.7±26.7/49.6±57.3 IU/L. LD 678.3±50.1 IU/L. total bilirubin 1.6±0.9mg/dl- The all cases were treated suscessfully with hydroxychloroquine and primaquine. There were no central nervous system complications and pulmonary edema. Conclusion : Malaria is one of the important acute febrile illness with the high incidence between July and August.

      • KCI등재

        주물공장 근로자에서 발생한 국한성 석면폐증 1예

        김태우,고동희,김민기,유승원,류향우,한정희,정순희 大韓産業醫學會 2009 대한직업환경의학회지 Vol.21 No.2

        배경: 주물공장 근로자에서 발생한 석면폐증의 작업 관련성을 평가하고 그 증례를 보고하고자 한다. 증례: 30년간 주물공장에서 근무한 환자로 인후통, 기침, 노란 가래가 있어 검사한 결과 결핵이 의심되어 치료 하였으며, 치료 중 석면폐증으로 진단되었다. 작업 관련성 평가를 위해 실시한 폐 조직의 조직학적 검사에서 1 cm^(2)당 3개의 석면소체가 발견되었고, 투과전자현미경으로 분석한 석면 함유량은 23.26x10^(6) fibers/g이었다. 결론: 작업환경조사, 폐 조직의 석면 분석 등을 통해 작업 관련성이 높다고 판단하였다. Background: Foundry workers are known to be exposed to silica and have an increased risk of Silicosis. There are also reports that state these foundry workers were associated with asbestos-related change in the X-ray results of the lungs. This report discusses a case of localized asbestosis developed in a foundry worker who worked in 12 Korean foundries. Case report: A 49-year-o1d man who worked at molding and melting for 30 years, Presented with sore throat, cough and yellow sputum for 1 month. From physical and clinical examination, Pulmonary tuberculosis was highly suspicious; therefore, he was medicated for 6 months. After tuberculosis medication, the radiological finding was reactivation of tuberculosis, and an asbestos body was detected at a trans-bronchial lung biopsy. During an operation, operators found multiple palpable masses and bullae 10calized in the right upper lobe (RUL) and performed right upper lobectomy and right middle lobe wedge resection. Using hematoxylin-eosin stain and iron stain, we could detect asbestos bodies by light microscopy. We analyzed the asbestos fiber burden in dry lung tissue by transmission electron microscopy with energy dispersive X-ray spectrometer (TEM-EDX). The fiber type was chrysotile and the fiber burden was 23.26 x 10^(6) fiber/g dry lung. Discussion: This case study of a foundry worker with localized asbestosis is uncommon in Korea. We found an occupational relationship between the foundry worker and localized asbestosis through various investigative techniques such as measurements taken at his working environment, clinical, radiological and pathological examination of the foundry worker and mineralogical examination of the asbestos fiber.

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