In vitro Mammalian Chromosomal Aberration Test of Fullerene-C60

Soo Jin Kim(김수진),Kyung Taek Rim(임경택),Hae Won Cho(조해원),Jeong Hee Han(한정희),Hyeon Yeong Kim(김현영),Jeong Sun Yang(양정선) 환경독성보건학회 2009 환경독성보건학회지 Vol.24 No.1

Fullerene의 유전독성을 평가하기 위하여 Chinese hamster유래의 난소유아세포(CHO-K1 cell)를 이용하여 직접법(-S9)과 대사활성화법(+S9 mix)의 염색체이상시험을 실시하였다. 시험물질은 1% CMC 나트륨염의 현탁액(l% CMC 용액)에 희석하여 조제하였다. 대사활성화를 시키지 않은 직접법의 염색체이상시험에서 24시간 투여군은 8단계의 농도(0.078, 0.156, 0.313, 0.625, 1.25, 2.5, 5, 10mM)로 투여하여 실시하였다. 투여 농도 증가에 따른 염색체이상의 빈도가 증가하는 양상이 나타나지 않았다. 48시간의 투여군에서는 8단계의 농도(0.078, 0.156, 0.313, 0.625, 1.25, 2.5, 5, 10mM)로 투여하여 실시하였는데 투여 농도 증가에 따른 염색체이상의 빈도가 증가하는 양상이 나타나지 않았다. 배수체의 염색체이상은 직접법에서 관찰되지 않았다. 대사활성화법을 이용하여 6시간 시험물질을 투여한 시험에 있어서는 8단계의 용량단계 (0.078, 0.156, 0.313, 0.625, 1.25, 2.5, 5, 10mM)를 설정하였는데 투여 농도가 증가함에 따른 염색체이상빈도의 증가양상이 관찰되지 않았다. 이상의 결과를 종합할 때 본 시험물질은 본 시험 조건하에서 CHO-K1세포에서 대사활성화를 시켰을 때 염색체 이상을 유발하지 않는 것으로 판단된다.

벌매 Pernis ptilorhynchus의 번식보고

조해진(Hae-Jin Cho1),이영석(Young-Suk Lee),강태한(Tae-Han Kang),김인규(In-Kyu Kim),우희철(Hee-Chul Woo),이한수(Han-Soo Lee) 한국조류학회II 2010 한국조류학회지 Vol.17 No.1

2009년 8월 16일 강원도 홍천군 북방면 일대에서 벌매의 번식을 확인하였다. 이 종은 국내에는 번식하는 것으로 추정은 하고 있었지만, 실제 번식 둥지가 확인된 것은 첫 사례라고 할 수 있을 것이다. 이에 번식에 대한 보고하고자 한다. On 16 August 2009, Nest of Oriental Honey Buzzard (Pernis ptilorhynchus) was observed at Bukbang-myeon, Hongcheon-Gun, Gangwon-Do Province. This species was known to breed in korea, but actual breeding nest was not observed. This is the first record of observed breeding nest of the Oriental Honey Buzzard in korea.

現代思想과 靑年文化 : 哲學的 敎育學的 思想을 中心으로

趙鏞振,徐海吉 충남대학교 미국학연구소 1976 美國學論文集 Vol.1 No.-

Ⅰ. Cultural situations are classified into several parts : traditional culture and alien culture, pure and popular, main stream and non main stream, and finally youth culture. Among other cultures, we can not overlook youth culture, which is closely related to modern culture and civilization. First of all, we must have good knowledge of the youth culture: what it is, how it is composed on what value it is made, what type of thought pattern the modern youth who live in the current technical civilization have My purpose in this paper is to study these problems from the viewpoint of philosophy and education. Ⅱ. If our life is comparable to a tree, the child period is the period of seed growing, the adolescent period is that of blooming in preparation for bearing fruit, and the senescence period is that of bearing fruit ready to fall. The culture formed during the adolescent period has something to do with the establishment fo the co-ordinates of our life. Culture is chiefly formed by what the adolescents think of and what they do during the adolescent period. Ⅲ. The youth culture has at present a seriously significant task of modern thought and humanism, since their resentment, renunciation, resistance, suspense, despair and delinquency are closely related to the social problems. Very tight problems might arouse without the accurate knowledge of the youth culture. The adolescent period is not the transition period but the period when we can from individual views. Ⅳ. Their resistance, secession, irresponsibility, alienation, egoistic mind, enervation etc. have become a challenge against our traditional culture. Therefore we can not bur relate this youth culture with the social problems. Social agreement and open tendency play a significant role in the formation of the youth culture. By means of research on the relationship between the youth culture and the modern thought, that is, between the youth culture and Pragmatism, Instrumentalism, Operationsim, I have attempted to grasp the true character of the youth culture. Ⅴ. I have analyzed complex factors of the youh culture and examined into J. Deway's educational view in addition to T. Brameld's viewpoint. Dewey pointed out the irrationality of their respective viewpoints between traditional education and progressive education and made both the extreme viewpoints harmonized by means of philosophical methods. It is deemed to be a desirable method to tie and harmonize traditional culture and youth culture. According to Dewey, education is the very cultivation of its ability and education is achieved by forming the habit of "Reflective thought" Therefore the forming of "Reflective thought" means tha we can make the adolescent adapted to circumstance and guide them into the right path. Ⅵ. Brameld's reconstructionism is based on the idea that we can not overcome present crisis by means of progressivism and essentialism, but consolidated theory which was adopted from the advantages of both the ideas. The core of Brame;d's thought is the construction of democratic world culture and the realization of social self. As a means of principle to achieve the above, he took social agreement. The social agreement is made by means of social persuation through communication of individual desire. The youth culture must also be assimilated through this method. It is my conviction that Brameld's theory to construct Utopian world is our ultimate educational goal and thought.

인공토양 생산과 인공지반에 이용방안에 관한 연구

조해용,김진용,김성민 선문대학교 ·중소기업기술지원연구소 2002 선문공대 연구/기술 논문집 Vol.7 No.1

인공토양을 생산하기 위해 점토와 톱밥에 첨가제를 사용하여 혼합한 재료는 화로에서 300~400℃로 약 20분 정도 처리하였다. 인공토양이 인공지반에서 토양의 조건으로 적당한가를 조사하기 위해서 인공토양의 물리·화학적 특성을 분석하였다. 인공토양의 입자크기는 직경 1.5~8㎜ 이었고, 점토토양과 펄라이트A와 비교해서 투수성, 총 질소 그리고 총 인이 높았다. 또한 인공지반의 녹화를 위한 경량토로서 펄라이트를 대신 인공토양을 이용하면 경제적인 효과가 기대된다. For the production of artificial soil, a mixture of clay saw dust as additives was formulated, and was thermally treated in the firing kiln at 300-400℃ for about 20minutes. The physico-chemical characteristics of the artificial soil were analyzed, in order to be used as a soil conditions to the artificial ground. The particle sizes of artificial soil were controlled to 1.5~8㎜ in diameter. Artificial soil showed high in permeablility, total nitrogen and total phosphorous concentration compared to the clay soil and perlite. In addition, artificial soil could be a cost-effective substitute for perlite as a light material for greening of artificial ground.

소아에서의 급성 파종성 뇌척수염의 임상적 고찰

조수진,박은애,유은선,김혜순,손세정,서정완,이승주,한후재 이화여자대학교 의과대학 2003 EMJ (Ewha medical journal) Vol.26 No.2

목적: 급성 파종성 뇌척수염은 감염이나 예방 접종 후 발생하는 중추 신경계의 급성 자가 면역 염증성 질환으로 탈수초를 일으킨다. 신경학적인 증상으로 발현되고 대부분 환전히 회복되지만 신경학적 후유증을 남기거나 사망 할 수도 있다. 이에 저자들은 본원에서 발생 한 14명을 분석하여 조기 진단과 치료에 도움을 주고자 하였다. 대상과 방법: 1998년 3월부터 2003년 8월까지 이대목동병원에서 급성 파종성 뇌척수염으로 진단 받은 14명의 의무기록을 후향적으로 조사하였다. 결과: 환자들의 평균 발생 연령은 5±7.8개월이였고, 특정계절이나 연도에 집중되어서 나타나지는 않았다. 선행질환은 주로 비특이적인 상기도 감염이 가장 많았고, 초기증상으로는 경련이 가장 많았다. 그 외에 의식저하나 운동장애도 있었다. 뇌척수액 검사에서 백혈구 증가증이 발견된 경우는 있었으나 단백이 증가된 경우는 없었다. 뇌 자기공명 촬영에서 T2 증강시 뇌백질과 기저핵에 고음영의 다발성 병소가 발견되었고 추적 촬영에서 대부분에서 소실되었다. 뇌파 검사가 시행되었던 경우 전반적인 서파가 가장 많았고 국소적인 극파가 나온 경우도 한 명 있었다. 환자들은 정맥 면역 글로블린과 메틸프레드니졸론으로 치료하였고 치료 시작 후 3~7일내 증상이 호전되었다. 모든 환자를 2달 이상 추적 관찰하였고 항경련제가 지속적으로 필요한 정도의 경련성 질환이 두 명, 신경아교증이 남아잇는 경우가 한 명, 외래에서 다발성 경화증이 의심되는 경우가 한 명 있었다. 결론: 급성 파종성 뇌척수염은 침범 부위에 따라서 다양한 임상 상으로 나타나며 면역 글로블린과 메틸프레드니졸론이 치료에 효과적이였다. 본 연구에서는 대상 환자수가 적어 신경학적 후유증의 위험요소는 밝힐 수는 없으나, 예후는 검사소견과 연관되어 있지는 않았고, 대부분에서 양호하여 완전히 회복되었으나, 신경학적 후유증이 남은 경우도 있었다. Objective:Acute disseminated encephalomyelitis(ADEM) is an acute demyelinating autoimmune inflammatory disease of the central nervous system which develops after infection of vaccination. It may be fatal, and produce a permanent residual static disability or fully recover. We retrospec-tively studied 14 cases to investigate the clinical findings and outcome of ADEM. Methods : 14cases of ADEM diagnosed at Ewha Womans University Mokdong Hospital from 1998 to 2003 were retrospectively reviewed. Results : The age of onset was 5years±7.8 months and no seasonal clustering was found. The time of onset of symptoms was between 3 to 30 days. The preceding events were nonspecific upper respiratory infections in 9 cases, aseptic meningitis in 4 cases, and gastroenteritis in one case..The initial symptoms were seizure, altered consciousness, hemiparesis, fever, headache, and vomiting. Brain MRI showed multifocal high signal intensity lesions on T2 weighted image mainly in the cerebral whith matter, basal ganglia and periventricular white matter. EEG was performed in some cases and showed generalized or focal slow waves and only one case showed focal spikes. Patients were treated with IV globulin and methylprednisolone and the symptoms improved within 3-7 days after treatment. All patients were followed up for more than 2 months and most of them fully recovered except two. Conclusion : ADEM presents in various clinical manifestations depending on its involvement of the brain lesions. Most cases recovered fully but in some cases, residual permanent neurologic sequelae remained.

들민달팽이(Deroveras varians)의 배자발육과 난황단백질

진병래,손흥대,박혜진,조은숙 東亞大學校附設 農業生命科學硏究所 1999 農業生命資援硏究 Vol.8 No.1

들민달팽이의 배자발육은 해부현미경으로 관찰하였다. 산란 후 4일이 경과면서 발육이 급격하게 진전되어, 10일이 지나면서 난 내에서 들민달팽이 유충의 형태를 갖추고, 12일째 부화하였다. 들민달팽이의 배자발육에 따른 난황단백질의 변화는 산란 1일째, 3일째 및 6일째 알의 난황단백질을 전기영동방법으로 분석하였다. 그 결과 배자발육과 함께 급격히 감소되는 난황단백질 관련 밴드를 관찰할 수 있었다. We characterized embryogenesis and egg proteins of Variable field Slug, Deroceras varians. The embryogenesis was observed by light microscopy. The eggs were hatched at the twelfth day after oviposition. The egg proteins of the first day, third day and sixth day after oviposition were analyzed by native-and SDS-PAGE analyses. The results showed that yolk proteins are gradually decreased during embryogenesis.

최근 10년간 마취에 관한 임상적 고찰 (Ⅲ)

조현숙,김윤희,손수창,김혜자,최세진 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

To evaluate the specificity and the historical trends of the anesthetic agents and anesthetic methods used in Chungnam national university hospital, anesthetic experiences of 53,291 in total performed at Chungnam national university hospital from January 1987 to December 1996 were analized statistically and clinically according to age, sex, surgical department, physical status, elective to emergency surgery, premedicants, induction agents, anesthetic methods, main anesthetic agent, anesthetic technique and muscle relaxants. The results were as follows : L The number of cases has been steadily increased in annually. 2. The distribution of the number of patients according to the age were cases 37,309(70.02%) in the group of 13-60 years. 3. There were 27,448 male (51.5%) and 25,843 female (48.5%) cases. 4. 9,208 cases (17.27%) were OB-GY, 9,162 cases (17.19%) in general surgery, 7,936 cases(14.89%) in orthopedic surgery, and 6,079 cases (11.4%) in ENT in order of numbers. 5. According to the ASA classification of physical status , most of the cases were belonged to the class 1 (38.69%) class 2 (40.33%) class 1E (5.52%) class 2E (5.71%). Almost cases were relatively in good physical status. 6. The number of elective to emergency was 7,833 (89.76%), to 5,458 (10.24%) cases. 7. As premedicants, a group of glycopyrrolate (35.20%) was given most frequently. 8. Thiopental sodium has been mainly used for intravenous induction agent. 9. General anesthesia has been used as main method of anesthesia. 10. Enflurane was the most commonly used anesthetic agent. 11. Vecuronium was the most commonly used non-depolarizing muscle relaxant.

골반 내 농양 1예

조인숙,이해혁,김태희,이권해,남계현,이임순,김정식,박성진 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Pelvic inflammatory disease (PID) is a disease that affects young, sexually active, reproductive age women. Most pathogens are Chlamydia trachomatis and Neisseria Gonorrheae transmitted sexually. One of serious acute complication of PID is tubo-ovarian abscess (TOA) that involves the fallopian tube, ovary and adjacent structures (eg, bowel, pelvic peritoneum). The microbiology of TOAs is polymicrobial with anaerobic organisms and causal organisms of PID. Common anaerobic organisms are Peptostretococcus spp, Bacteriodes spp, Prevotella spp, Escherichia coli and aerobic streptococci. Treatment is necessary to admission for intravenous broad-spectrum antibiotics and surgery is often reserved for patients with suspected rupture or patients who fail to respond to antibiotics. So, we reported this case found pelvic abscess due to ruptured tube-ovarian abscess.

협대역 ISDN에서의 중대역 교환기능 실현에 관한 연구(Ⅰ) : 회선교환 모드에 의한 실현방안 Realization Scheme Based on the Circuit Switched Mode

曺圭燮,林海鎭 成均館大學校 科學技術硏究所 1993 論文集 Vol.44 No.2

Prior to the national narrowband ISDN commercial service, it is necessary to develop the wideband switching capability in order to prepare the needs for wideband services which are expected to increase rapidly in the near future. Among the wideband channels, HO channel switching is expected to be implemented based on the present narrowband ISDN switch. In the development of HO channel switching, both of circuit switched mode and packet switched mode must be implemented like narrowband case. In this paper, an implementation scheme of wideband switching function on the existing TDX-lB/ISDN switch based on the circuit switched mode is suggested. For this, we proposed multi-time slot assignment method using divided in two channel table and addition of dedicated wideband switch method which utilizes existing switch module. We also surveyed the applicability of the two methods to the TDX-1B/ISDN switch. Based on this survey, we finally proposed a implementation scheme adopting the two methods par tially.

Cyclophosphamide 투여 흰쥐에서 비타민 A가 창상파열력에 미치는 영향에 관한 실험적 연구

조해석,정상훈,임풍,김진철,안상태 大韓成形外科學會 1985 Archives of Plastic Surgery Vol.12 No.1

Cyclophosphamide lays restraints upon production of fibroblast and collagen fiber and reduce wound burst strength by acting on fibroblast in acute inflammatory phase. Vitamin A is known to increase inflammatory reaction by exerting an effect upon inflammatory cells in the beginning of the wound healing process. It shows contrary effect to cyclophosphamide. In order to study the influence of vitamin A over wound healing delay induced by cyclophosphamide in rats, we observed and compared the wound burst strength of cyclophosphamide and vitamin A combined treated group with those of control and cyclophosphamide treated group. Wound burst strength of each group was measured in the skin segments of 2×4cm obtained from the operation sites at the 3rd, 5th, 7th and 14th postoperative days after making 5cm incision and suture at the back of 72 rats. Results of the experiment are as follows; 1. Wound burst strength in control group increases slowly as days go by and shows trends of sudden increase between the 5th and 7th postoperative days. 2. Wound burst strength in cyclophosphamide treated group is markedly less than that in control group. 3. Wound burst strength in cyclophosphamide and vitamin a combined treated group shows similar level to that in control group. 4. Body weight in cyclophosphamide treated group reduces gradually as days go by. But there's no weight reduction in cyclophosphamide and vitamin A combined treated group. Judging from these results, we found the fact that vitamin A could prevent or recuperate the side effects of cyclophosphamide, delay of wound healing and worsening of general condition.