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직장으로 투여한 Misoprostol에 의해 조절된 산후출혈 3예.
이상은(Sang Eun Lee),황성욱(Seong Ook Hwang),고승권(Seung Kwon Kho),조숙(Sook Cho),임문환(Mun Hwan Lim),이우영(Woo Young Lee) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.8
Postpartum hemorrhage is an important cause of maternal mortality and morbidity. Especially uterine atony is the most common cause of postpartum hemorrhage. Conventional method to control postpartum uterine atonic bleeding is based on the use of oxytocin and ergot preparations. Prostaglandin F2α analogue such as carboprost can be used to promote contraction when these agents fail to produce uterine contraction. Prostaglandin E1 analogue, misoprostol has uterotonic effect by oral or vaginal administration. They are used to induce labor and first or mid trimester abortion. In postpartum uterine atonic bleeding, misoprostols cannot be used via oral or vaginal route. Recently we have experienced that postpartum uterine atonic bleedings unresponsive to conventional methods were controlled by rectal misoprostols. So we report these cases with a brief review of literatures.
이정례(Jeong Rye Lee),황성욱(Sung Ook Hwang),홍표(Pyo Hong),김세련(Se Ryon Kim),박지현(Jee Hyun Park),고승권(Seng Kweon Kho),이병익(Byuong Ick Lee) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.7
A heterotopic (combined) pregnancy, ectopic pregnancy accompanied by coexisting uterine pregnancy, is a rare phenomenon in general population. Recently, its incidence has increased significantly due to increased use of assisted reproductive technologies. But diagnosis of heterotopic pregnancy is often delayed or missed because heterotopic pregnancy is still rare and difficult to diagnose. We have a patient who had simultaneous intrauterine pregnancy and left tubal pregnancy after in vitro fertilization and embryo transfer. We performed left salpingectomy and she delivered 3.13 kg healthy female baby 32 weeks later. So we report this case with a brief review of the literatures.
악성 위험지수 (Risk of Malignancy Index) 1을 이용한 골반내 종양의 분석
박정우 ( Jung Woo Park ),황성욱 ( Sung Ook Hwang ),박지현 ( Jee Hyun Park ),이병익 ( Byoung Ick Lee ),이정훈 ( Jeong Hoon Lee ),김기원 ( Ki Won Kim ),김경미 ( Kyoung Mi Kim ),정민재 ( Min Jae Jung ),윤내리 ( Nae Ri Yun ),송은섭 ( 대한폐경학회 2013 대한폐경학회지 Vol.19 No.1
Objectives: To assess the ability of risk of malignancy index (RMI) 1 to discriminate between benign and malignant pelvic masses. Methods: Between January 2007 and December 2010, 547 women with pelvic masses were evaluated. Their medical records are reviewed here retrospectively. The sensitivity, specificity and positive and negative predictive values of the cancer antigen (CA) 125 level, ultrasound findings and menopausal status in the prediction of malignant pelvic masses were calculated and compared individually or combined using the RMI 1. Results: The receiver operating characteristic (ROC) curves of CA 125, the ultrasound score and the RMI 1 were all found to be relevant predictors of malignancy. ROC analysis of the RMI 1, CA 125 serum levels, ultrasound score and menopausal status showed areas under the curves of 0.795, 0.782, 0.784 and 0.594, respectively. The RMI 1 was found to be statistically significantly correlated with menopausal status (P = 0.001), while not statistically significantly correlated with CA 125 (P = 0.628) or the ultrasound score (P = 0.541). The RMI 1 at a cut-off of 150 - with a sensitivity of 77.9%, specificity of 81.1%, positive predictive value of 51.7% and negative predictive value of 93.4% - showed the highest performance in determining the malignant tendency of pelvic masses. Conclusion: Accepting a RMI 1 cut-off value of 150 results in statistically more significant diagnostic criteria than menopausal status for the discrimination of benign and malignant pelvic masses. (J Korean Soc Menopause 2013;19:18-25)
6 종류의 생식세포와 육종성 변화를 보인 혼합 생식세포종 1 예
방금화(Chin Hua Fang),박성민(Sung Min Park),송경은(Kyung Eun Song),송은섭(Eun Seop Song),임영구(Young Koo Lim),황성욱(Seong Ook Hwang),고승권(Seung Kwon Koh),조숙(Sook Cho),이우영(Woo Young Lee) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.1
Malignant germ cell tumors of the ovary are uncommon neoplasms. Although 20-25% of all ovarian tumors are derived from germ cells, only about 3% of germ cell tumors are malignant. Mixed germ cell tumors contain at least two malignant germ cell elements. These lesions should be managed with combination chemotherapy, preferably BEP. Recently we experienced a case of mixed germ cell tumor with 6 components of germ cell and sarcomatous change in a 11 year old girl. Preoperative CA-125, B-hCG, aFP, LDH, a-1-antitrypsin were elevated and the final pathologic report was mixed germ cell tumor composed of endodermal sinus tumor, embryonal carcinoma, mature and immature teratoma, choriocarcinoma, dysgerminoma and sarcomatous change, Postoperative chemotherapy with 6 courses of BEP regimen was performed and all tumor markers became normal after 4 courses of chemotherapy. What we interested in this case was several components of germ cells and sarcomatous change and the sarcomatous change might be derived from the mature cystic teratoma component, so we present this case with a brief review of the literatures here.
자궁경부 세포진 검사에서 미확정 편평세포의 임상적 의의와 적절한 처치
윤정묵(Jung Mook Yoon),이상은(Sang Eun Lee),황태율(Tae Yul Hwang),송경민(Kyung Min Song),홍표(Pyo Hong),민수기(Soo Kee Min),황성욱(Seong Ook Hwang),김준미(Joon Mee Kim),고승권(Seung Kwon Koh),조숙(Sook Cho),이우영(Woo Young Lee) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.8
N/A Objective : To evaluate the clinical significance and the optimal management of atypical squamous cells of undetermined significance (ASCUS) in Papanicolaou cervical smears. Method : This study included 25380 cases of cervical Pap smears received from January 1995 to June 2000 by the Department of Obstetrics & Gynecology, Inha Hospital, Medical College, the Inha University. Retrospective review was done on 384 cases of ASCUS. Result : ASCUS and squamous intraepithelial lesions (SIL) were diagnosed in 384 cases (1.5%), and 311 cases (1.1%), respectively. The ratio of ASCUS to SIL was 1.2. Colposcopic directed biopsies revealed 14 cases (14.1%) of low grade SIL (LSIL), 21 cases (21.2%) of high grade SIL (HSIL), and 2 cases (2.0%) of squamous cell carcinoma. Conclusion : The immediate colposcopy with biopsy in women with ASCUS may decrease follow-up visits for Pap testing, reduce patient anxiety, minimize the loss of high risk cases during follow-up and lower medicolegal litigation. The early colposcopy may be the method of choice for follow-up in women with ASCUS in Korea.
박정우 ( Jung Woo Park ),최석진 ( Suk Jin Choi ),박지현 ( Jee Hyun Park ),황성욱 ( Sung Ook Hwang ),정민재 ( Min Jae Jung ),송은섭 ( Suk Jin Choi ) 대한산부인과학회 2012 Obstetrics & Gynecology Science Vol.55 No.12
A 57-year-old Korean woman visited 37 months after initial surgery with fetal head sized pelvic mass. Initially, she underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, omentectomy, and para-aortic lymph node biopsy. The initial pathological report showed uterine smooth muscle tumors of uncertain malignant potential (STUMP). She had not received adjuvant therapy. Transvaginal ultrasound revealed multiple solid masses in the pelvic cavity. Abdomino-pelvic computed tomography scan revealed heterogeneous lobulated rounding masses. Tumor markers were all within the normal range. She underwent explorative laparotomy. The pathological diagnosis was epitheloid leiomyosarcoma. Patients with STUMP should be counseled regarding the potential for recurrence as leiomyosarcoma, and may require closer surveillance than a yearly.
송은섭 ( Eun Seop Song ),박지현 ( Jee Hyun Park ),황성욱 ( Sung Ook Hwang ),임문환 ( Moon Whan Im ),이병익 ( Byoung Ick Lee ),이우영 ( Woo Young Lee ) 대한산부인과학회 2010 Obstetrics & Gynecology Science Vol.53 No.5
목적: 우리나라의 자궁체암은 점차 늘어나고 있다. 저자들은 단일 기관에서의 자궁내막암 중에서 가장 흔한 세포형태인 자궁내막양 자궁내막암의 임상적 자료를 정리하여 보고하고자 한다. 연구 방법: 1998년부터 2009년까지 11년간 본 기관에서 자궁내막양 자궁내막암으로 진단받은 환자의 의무기록을 통하여 후향적으로 연구하였다. 결과: 연구기간 동안 자궁내막양 자궁내막암 환자는 총 96명이었다. 평균 나이는 51.1세, 평균 추적기간은 36.6개월이었다. 병기는 1기가 73명, 2기가 10명, 3기가 12명, 미확인이 1명이었다. 치료는 수술만 받은 경우가 42명, 수술 후 방사선치료를 받은 경우가 46명이었다. 수술을 받은 95명 중 32명은 림프절 제거 수술을 받지 않았고 63명은 받았으며, 이 중 10명에서 림프절양성이 나왔다. 사망은 총 6명이 있었으며 1기에서 한 명, 2기에서 3명, 3기에서 한 명이 있었다. 결론: 96례의 증례와 여러 치료법 및 림프절 제거 수술 등의 여부를 정리하여 제시하고자 하였다. Objective: The incidence of endometrial cancer is increasing. We would like to report our institution`s clinical data of endometrioid adenocarcinoma (EC) which is the most frequent type. Methods: From 1998 to 2009, patients` clinical data were reviewed through medical records, retrospectively. Results: For 11 years, there were 96 patients with EC. The average age was 51.1 years old and mean follow duration was 36.6 months. There were 73 patients with stage I, 10 patients with stage Ⅱ, and 12 patients with stage Ⅲ. 42 patients were treated by operation only and 46 patients were treated by operation and adjuvant radiotherapy. Among 95 patients who underwent operations, 32 patients did not get lymph node removal and 63 did, and 10 patients had malignant cells at the lymph nodes removed. 6 patients died of EC, 1 with stage I, 3 with stage Ⅱ and 1 with stage Ⅲ. Conclusion: This study had retrospective limitation but could show the profile of 96 patients with EC.