전측두엽 치매 증례

홍창형(Chang Hyung Hong),차경렬(Kyung Ryeol Cha),오병훈(Byoung Hoon Oh) 대한노인정신의학회 2003 노인정신의학 Vol.7 No.2

Frontotemporal lobe dementia have been underevaluated because of various clinical features, changing diagnostic criteria, and indifference of clinicians. It is important that frontotemporal lobe dementia patient showing behavioral and lingual problems should be early diagnosed and treated. Because frontotemporal lobe dementia patients often confused with Alzheimer's disease, senile depression, schizophrenia, drug abuse. We have presented a case of frontotemporal lobe dementia. He had typical clinical history and symptoms which deserve to be considered frontotemporal lobe dementia. He showed appropriate findings of frontotemporal lobe dementia in the neuropsychological tests and brain magnetic resonance imaging and single photon emission computed tomography. This case is thought to be helpful for clinicians to give attention to early diagnosis and appropriate treatment of frontotemporal lobe dementia.

군 병사들에서 인터넷 중독 경향에 따른 입대 후 심리특성 변화

강현묵,김현수,조현상,안석균,오병훈,이강수,홍창형,배활립,국소담,손상준,Kang, Hyun Mook,Kim, Hyun Soo,Cho, Hyun Sang,An, Suk Kyoon,Oh, Byoung Hoon,Lee, Kang Soo,Hong, Chang Hyung,Bae, Hwallip,Kook, So Dahm,Son, Sang Joon 대한생물정신의학회 2013 생물정신의학 Vol.20 No.3

Objectives The aim of this study was to find out the psychological changes associated with internet addiction between before and after the military drill among the young male army recruits. Methods All 1091 participants were army recruits aged from 19 to 22 years who participated in the 5-week military drill. They were assessed with some self-reported questionnaires [Sociodemographic questionnaires, Young's Internet Addiction Scale (IAS), the State-Trait Anxiety Inventory (STAI), the Beck Depression Inventory (BDI), the Barratt Impulsiveness Scale (BIS), the Attention-Deficit/Hyperactivity Disorder Self-Rated Scale (ASRS)]. They were divided into two groups, One is the internet addiction tendency group and the other is non-addiction group according to the IAS score. And the severity of the internet addiction tendency, depression, anxiety and impulsiveness were evaluated by the IAS, the STAI, the BDI, the BIS, the ASRS before and after military drill. Results The result of the paired t-test shows that the IAS, the STAI, the BDI, the BIS, the ASRS scores decreased after military drill in both non-addiction group and internet addiction tendency group. The result of the repeated measures ANOVA shows that there is an interaction effect between the changes of ASRS-hyperactivity (F = 23.437, p < 0.001), ASRS-impulsiveness (F = 4.896, p = 0.027), BIS-total (F = 4.057, p = 0.044), BIS-motor impulsiveness (F = 13.609, p < 0.001) scores and groups. The result of the generalized estimating equation shows that internet addiction tendency is associated with ASRS-inattention (${\beta}=0.075$, p < 0.001), ASRS-hyperactivity (${\beta}=0.092$, p = 0.002), STAI-trait anxiety (${\beta}=0.046$, p < 0.001), BIS-motor impulsiveness (${\beta}=0.119$, p = 0.028). Conclusions The results show that psychopathologies such as internet addiction tendency, depression, anxiety, impulsiveness may improve after military drill regardless of the groups. Internet addiction tendency may be related to the ASRS-inattention, ASRS-hyperactivity, STAI-trait anxiety, motor-impulsiveness. So these findings may be considered in the treatment of internet addiction in terms of the impulsiveness control.

노년기 주관적 기억력 감퇴와 인지기능의 연관성

장기중(Ki Jung Chang),이강수(Kang Soo Lee),김현정(Hyun Jung Kim),정해관(Hae Kwan Cheong),오병훈(Byoung Hoon Oh),홍창형(Chang Hyung Hong) 대한노인정신의학회 2009 노인정신의학 Vol.13 No.2

Objectives : We aimed to investigate the relationship between subjective memory complaints and cognition in the elderly. Methods : Data obtained from 1,496 subjects (510 men and 986 women) aged above 60 years was analyzed from the Gwangju Dementia and Mild Cognitive Impairment Study (GDEMCIS). All subjects completed the study questionnaire including demographic characteristics, history of current and past illnesses, drug history, Korean version-Mini Mental State Examination (K-MMSE), and Short Form Korean version of Geriatric depression scale (SGDS-K). Subjective memory complaints were defined in two different ways;worse than others (SMC-O) and worse than one's past (SMC-P). Results : On analysis of covariance, there was significant difference of estimated marginal means of K-MMSE score among five SMC-P groups (much improve : 18.0, little improve : 21.3, not changed : 21.2, little worse : 21.1, much worse : 20.2) after adjusting age, sex, educational level and depression (F=9.63, df=4, p<0.0001, adjusted R2=0.375). There was significant difference of estimated marginal means of K-MMSE score among three SMC-O groups (below peer's average : 20.4, peer's average : 20.9, above peer's average : 21.8) after adjusting age, sex, educational level and depression (F=4.89, df=2, p=0.043, adjusted R2=0.0.361). Conclusion : These results suggest that subjective memory complaints may be an indicator of objective cognitive impairment in the elderly.

MIND 식단교육을 이용한 치매예방 영양프로그램이 고위험 치매노인의 인지기능 변화에 미치는 영향

송재은 ( Jaeeun Song ),최성혜 ( Seong Hye Choi ),홍창형 ( Chang Hyung Hong ),정지향 ( Jee Hyang Jeong ),문소영 ( So Young Moon ),나해리 ( Hae Ri Na ),박희경 ( Hee Kyung Park ),박유경 ( Yoo Kyoung Park ) 대한영양사협회 2021 대한영양사협회 학술지 Vol.27 No.4

This study examined the effect of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet of the Korean multi-domain dementia prevention program on the cognitive functions of the elderly with dementia risk factors. We developed the program including nutrition, exercise, cognitive training, vascular disease prevention, and motivation. One- hundred and fifty-three participants aged 60∼79 years with at least 1 dementia risk factor were randomly assigned in a 1:1:1 ratio to the facility-based intervention (FMI), home-based intervention (HMI), and the control group. The nutrition education program consisted of 10 classes over 24 weeks: the FMI received 7 group sessions and three 1:1 sessions, the HMI received 4 group sessions and three 1:1 sessions with 3 homework sessions. The Nutrition Quotient for Elderly (NQ-E) and the Mini Nutritional Assessment (MNA) were used to evaluate nutritional status. The Repeatable Battery for the Assessment Neuropsychological Status (RBANS), Korean Mini-Mental State Examination (K-MMSE), and the Cognitive Complaint Interview (CCI) were used to evaluate cognitive functions. A total of 136 people completed the program with an 11.1% dropout rate. The NQ-E (P=0.009) and RBANS (P=0.001) scores significantly increased in the FMI (N=45) and HMI (N=49) groups compared to the control group (N=42) after the study. The changes in the score of MNA and CCI did not differ significantly between groups. In conclusion, the nutritional intervention which focused on the MIND diet as a part of a multi-domain intervention program had a positive effect on the improvement of healthy eating habits and cognitive function scores in the high-risk dementia group.

노인성 우울증 환자에서 지역사회 기반 ‘목표달성 프로그램’의 효용성

강규하(Gyu Ha Kang),장기중(Ki Jung Chang),임현국(Hyun Kook Lim),한진주(Jin joo Han),이은희(Eun Hee Lee),노현웅(Hyun Woong Roh),노재성(Jai Sung Noh),정영기(Young Ki Chung),임기영(Ki Young Lim),홍창형(Chang Hyung Hong),손상준(Sang Joon 대한노인정신의학회 2017 노인정신의학 Vol.21 No.1

Objective:This study aimed to investigate the effect of community-based Goal-Achieving program in geriatric depressive symptoms preliminarily. Methods:We obtained data from elderly Korean subjects with major depressive disorder (n=51) aged 60 years or older at baseline, taking case management from community mental health center. Subjects were randomly assigned to intervention group (n=24) and control group (n=27). We investigated depressive symptoms through Short Form Geriatric Depression Scale-Korean version (SGDS-K) at baseline and every month for 3 months to all subjects. We tested interaction between group and time in SGDSK score to evaluate the effect of program. And post hoc test examined between group differences of SGDS-K at each time points. Results:In quadratic linear mixed effects model analysis, interaction between group and time was statistically significant (Total SGDS-K score : coefficient=0.29, p<0.001 ; SGDS-K dysphoria subscale : 0.18, p<0.001 ; SGDS-K hopelessness subscale : 0.05, p=0.089 ; SGDS-K cognitive impairment subscale : 0.06, p=0.003). And significant between group difference was shown in post hoc test at time points of third month (SGDS-K score of control group : SGDS-K score of intervention group=10.74±3.482 : 7.25±4.475, p=0.0184). Conclusion:These results may suggest that ‘Community-based the Goal-Achieving program’ has efficacy in reducing geriatric depressive symptoms.

알츠하이머병 진행 예측을 위한 전향적 분류 알고리즘

박성홍(Sunghong Park),이동기(Dong-gi Lee),홍창형(Chang Hyung Hong),신현정(Hyunjung Shin) 한국정보과학회 2022 한국정보과학회 학술발표논문집 Vol.2022 No.06

지역사회 노인에서 머리둘레와 시공간 능력과의 연관성

김경란(Kyung Ran Kim),이강수(Kang Soo Lee),홍창형(Chang Hyung Hong),정해관(Hae Kwan Cheong),오병훈(Byoung Hoon Oh) 대한노인정신의학회 2007 노인정신의학 Vol.11 No.2

Objectives : The aim of this study is to find out the correlation between head circumference and visuospatial function of the elderly in community. Methods : A total of 463 subjects (170 men and 293 women) aged 60-91 years were analyzed from preliminary data of GDEMCIS (Gwangju Dementia and MCI Study). The study questionnaire consisted of demographic characteristics, current and past illness history, drug history, K-MMSE, SNSB-D. We also measured head circumference and examined ApoE genotype. Results : On regression analysis, as head circumference become smaller, visuospatial memory scores (S-Rey immediate recall & delayed recall) decreased adjusted by age, height, sex, educational level, ApoE ε4 allele, current smoking and alcohol drinking (β=0.18, p=0.002, β=0.15, p=0.01). Presence of ApoE ε4 allele has no direct correlation with head circumference and cognitive decline. Conclusion : As head circumference become smaller, only visuospatial memory scores decreased significantly. These results suggest that visuospatial memory function might be one of the sensitive markers of brain reserve differences.

지역사회 노인에서 불안과 뇌졸중 경고증상의 관계

이수현(Su Hyun Lee),고상현(Sang Hyun Koh),이윤환(Yunhwan Lee),백종환(Joung Hwan Back),정영기(Young Ki Chung),김현정(Hyun Chung Kim),홍창형(Chang Hyung Hong) 대한노인정신의학회 2011 노인정신의학 Vol.15 No.1

Objectives:We aimed to investigate the relationship between anxiety and stroke warning signs in the elderly. Methods:Data obtained from 1,078 subjects (256 men and 822 women) aged above 65 years was analyzed from Suwon Project, which was a cohort comprising of nonrandom convenience samples. All the subjects completed the study questionnaire including their demographic characteristics, history of current and past illnesses, drug history, Korean version-Mini Mental State Examination (K-MMSE), SGDS-K (Korean version of the Geriatric Depression Scale-Short Form), BAI (Beck Anxiety Inventory). Stroke warning signs were defined as 5 stroke warning signs consistent with the American heart association public health message Results:There was significant relationship of anxiety and the number of stroke warning signs after adjusting age, sex, educational level and depression (β=2.145, p〈0.0001). On analysis of covariance, the interaction of the number of experienced stroke warning signs with sex on anxiety was observed after adjusting for the age, educational level, K-MMSE, and SGDS-K (p=0.011). Conclusion:These results suggest that there was significant relationship of anxiety and stroke the elderly.

시군별 보건소의 치매관리 현황분석

이강수(Kang Soo Lee),이동우(Dong Woo Lee),이준영(Jun Young Lee),정해관(Hae Kwan Cheong),김경란(Kyung Ran Kim),최지혜(Ji Hey Choi),오병훈(Byoung Hoon Oh),홍창형(Chang Hyung Hong) 대한노인정신의학회 2006 노인정신의학 Vol.10 No.2

Objectives : The purpose of this study was as follows : 1) to compare the current status of management for dementia between city and country health center. 2) to check the amount and detailed items of budgets for dementia in dementia counseling center, referral courses for registration of dementia patient, number of dementia patient referred to welfare institutions for the elderly. 3) to understand the troubles in management for dementia in health center and to provide baseline data about future community dementia management system. Method : The questionnaire was administered to 248 public health centers. The 162 collected questionnaires were used in analysis and the whole response rate was 65.3%. Questionnaire composed by general contents about dementia management in health center and dementia counseling center. Statistical analysis was conducted to compare the difference about each item in city and country health center. Results : City and country health center showed differences in number of registered dementia patient, budgets for dementia, referral courses for registration of dementia patient, number of dementia patient referred to institution, troubles in management for dementia in health center. Conclusion : Current dementia management system does not meet the various needs of community for management of dementia. Thus, complementary strategies are needed to solve this problem.

지역사회 노인의 인지기능과 정신적 활동의 연관성

여현철(Hyun Chul Yuh),고상현(Sang Hyun Koh),이윤환(Yunhwan Lee),백종환(Joung Hwan Back),임기영(Ki Young Lim),김현정(Hyun Chung Kim),홍창형(Chang Hyung Hong) 대한노인정신의학회 2011 노인정신의학 Vol.15 No.1

Objectives:The purpose of this study was to describe the status of mental activity participation in community-dwelling elderly and to evaluate the association between mental activity and cognitive function after adjustment for depression and anxiety. Methods:This study was based on the Suwon Project, which was a cohort comprising of nonrandom convenience samples of ethnic Koreans aged 60 years and above. All the subjects completed the study questionnaire including their demographic characteristics, current and past illnesses history, drug history, Korean version-Mini Mental State Examination (K-MMSE), Korean version of Short Form Geriatric Depression Scale (SGDS-K), Beck Anxiety Inventory (BAI). We checked how many hours per day are used for each items of 11 mental activities through the checklist. Results:Total time spent in 11 mental activities was 237.4±152.4 minutes per day. On multiple regression analysis, total time spent in 11 mental activities (MA-total), and time spent by watching television and reading book/newspaper showed statistically significant association with K-MMSE score after adjustment with age, sex, education, chronic medical illness, depression and anxiety. Conclusion:Our result suggested that mental activity may be associated with cognitive function in the elderly without cognitive impairment in the community after adjusting age, sex, education, chronic medical illness, depression and anxiety.