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장미란 ( Mi Ran Jang ),박혜진 ( Hye Jin Park ),홍은영 ( Eun Yeong Hong ),김건희 ( Gun Hee Kim ) 한국식품조리과학회(구 한국조리과학회) 2014 한국식품조리과학회지 Vol.30 No.3
This study was investigated the antibacterial activities of Cirsium japonicum from extracts five regions(Chungnam, Gyeonggi, Gangwon, Jeju and Jeonnam) extract against six food-borne pathogenes(Bacillus cereus, Bacillus subtilis, Staphylococcus aureus, Listeria monocytogenes, Salmonella enterica and Vibrio vulnificus) using the broth dilution and agar diffusion method. At concentrations between 0 and 750μg/mL the extracts showed an antibacterial effect against all tested bacteria. The antibacterial activities of Cirsium japonicum from Jeju and Gangwon are stronger than others. The minimum inhibitory concentration(MIC) values against the six bacteria ranged from 93.75 to 750μg/mL. In time killing assay(cell growth curves), the tested bacteria inactivated upon exposure to the extracts for 24h. At the 24h exposure to the extracts, all bacteria were inhibited to over 70% for growth. In particular, Bacillus subtilis, Salmonella enterica and Vibrio vulnificus conveyed an inhibition of growth to almost complete. It is anticipated that Cirsium japonicum extracts may have greater potential as natural food preservatives.
증례 : 혈관염으로 인한 혈담낭염이 발생한 현미경적 다발혈관염 1예
한지숙 ( Ji Suk Han ),이성연 ( Sung Yeon Lee ),김형직 ( Hyung Jik Kim ),송영림 ( Young Rim Song ),김좌경 ( Jwa Kyung Kim ),홍은영 ( Eun Yeong Hong ),민수기 ( Soo Ki Min ) 대한내과학회 2012 대한내과학회지 Vol.83 No.1
PAN에 의한 담낭 혈관염과 혈담낭염에 대한 보고도 있으나, 현미경적 다발혈관염에 의한 담낭염 및 담낭내 출혈은 저자들이 처음으로 증례 보고하는 바이다. Microscopic polyangiitis (MPA) is a systemic necrotizing vasculitis, primarily associated with rapidly progressive glomerulonephritis and alveolar hemorrhage. Approximately 50% of MPA cases are associated with gastrointestinal involvement, but rarely do cases involve the gall bladder. We report an unusual case of MPA complicated by hemocholecystitis. A 62-year-old woman was admitted to our hospital with rapidly progressive renal dysfunction and pneumonia unresponsive to antibiotics, A chest CT scan showed bilateral diffuse alveolar consolidation, and perinuclear anti-neutrophil cytoplasmic antibody (p-ANCA) staining was positive. During the course of hospitalization, the patient complained of severe abdominal pain, and an abdominal CT scan revealed acalculous cholecystitis with hemorrhage. Cholecystectomy was performed, and a gall bladder biopsy revealed fibrinoid necrosis of small arteries without granuloma. Cholecystitis should be considered in patients with unexplained upper abdominal pain and MPA.
증례 : 내분비-대사 ; 전립선암 남성호르몬 박탈 치료 후 발생한 비케톤성 고삼투압성 혼수 1예
이석원 ( Seok Won Lee ),이성진 ( Seong Jin Lee ),유형준 ( Hyung Joon Yoo ),강준구 ( Jun Goo Kang ),임성희 ( Sung Hee Ihm ),김철식 ( Chul Sik Kim ),홍은영 ( Eun Yeong Hong ) 대한내과학회 2010 대한내과학회지 Vol.79 No.5
저자들은 골(骨) 전이를 동반한 전립선암으로 남성호르몬 박탈 치료를 받던 중 제2형 당뇨병, 비케톤성 고삼투압성 혼수, 급성 신부전이 발생하여 충분한 수액공급과 인슐린 투여 등의 집중 치료를 시행한 후 호전된 증례를 처음으로 경험 하였기에 문헌고찰과 함께 보고하는 바이다. During advanced prostate cancer, androgen deprivation therapy (ADT) using gonadotropin-releasing hormone and antiandrogen is an effective treatment modality. Recently, it has been reported that ADT may result in diabetes mellitus (DM), metabolic syndrome, and cardiovascular disease. Here, we report the first case in the literature of new-onset DM and hyperosmolar nonketotic coma (HNKC) associated with ADT. A 69-year-old man visited our hospital because of altered mentality. The patient had been taking leuprolide and bicalutamide for metastatic prostate cancer for the past 4 months. In laboratory tests, new-onset DM with HNKC was diagnosed. The patient was immediately treated with intravenous hydration and insulin therapy, and recovered without sequela. Because ADT can cause DM, or rarely HNKC, it is necessary to monitor fasting blood glucose and lipid profiles carefully while ADT is performed. (Korean J Med 79:573-576, 2010)