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원종근(Jong Kewn Won),현인규(In Kyu Hyun),지남웅(Nam Woong Jee),김문홍(Moon Hong Kim) 한국유럽학회 1995 유럽연구 Vol.3 No.1
This paper traces back the essence of Eu integration the in depth study on the EU`s Common Commercial Policy (CCP). the main philosophy of CCP is placed on the abolition of trade barriers and thereby the expansion of liberalized World trade. Through the execution of CCP, EU member stares aim at the realisation of genuine single market of Europe. The major instruments of CCP include internal and external trade agreements, common external tariff rules and the non tariff barriers. CCP also strengthens the bargaining power of EU member states in the trade negotiations with external non member states. Even though CCP is basically oriented toward the liberalization of the work trade, some of the main instruments such as rules of origin and local content ratio and the and dumping measures are regarded protectionistic by external world.
폐렴진단에 있어서 Protected Specimen Brushing 의 역할
이재명(Jae Myung Lee),김동규(Dong Kyu Kim),최정은(Jeong Eun Choi),김동환(Dong Hwan Kim),모은경(Eun Kyung Mo),박명재(Myung Jae Park),이명구(Myung Goo Lee),현인규(In Gyu Hyun),정기석(Ki Suck Jung) 대한내과학회 1997 대한내과학회지 Vol.53 No.2
N/A Objectives: Culture of sputum is apt to be contaminated through oral cavity and proximal airway. Therefore, identification of true etiologic agents by sputum culture is not always reliable. In order to differentiate the pulmonary infection from non-infectious disease and to identify the true etiologic agent of acute pulmonary infection, we used PSB(Protected Specimen Brushing) and evaluated the efficacy of PSB. Methods: In 168 patients with acute febrile illness with pulmonary infiltrations(male 106, female: 61, mean age: 49.5±17.6), we performed PSB via a bronchoscope and compared the results along with blood culture and sputum culture. Protected specimen brush was introduced through biopsy channel of bronchoscope and was rotated within the purulent secretions. Tip of the brush was severed with aseptic technique and was immersed in 1cc of Ringer's lactate solution and vigorously mixed for 1 minute. The specimen was submitted for quantitative culture within 15 minutes and was regarded positive culture if colony forming units were above 10³/ml. Results: Using PSB for the diagnosis of pulmonary infection, sensitivity was 71.1% and specificity was 84.296. PSB was helpful in identifing true etiologic agent among several potentially pathogenic organisms. Using PSB for the diagnosis of UAP (ventilator associated pneumonia), sensitivity was 72.4% and specificity was 100%. Conclusion: Use of PSB can be a helpful method for the diagnosis of pulmonary infection and identification of its etiologic agents.
의과대학생의 청진 교육에 있어서 멀티미디어 이용의 효과
박명재(Myung Jae Park),이명구(Myung Goo Lee),김동규(Dong Kyu Kim),모은경(Eun Kyung Mo),현인규(In Gyu Hyun),정기석(Ki Suck Jung) 대한내과학회 1998 대한내과학회지 Vol.54 No.6
N/A Background: Auscultation of lung sound is a fundamental component of physical examination of respiratory disease. It is difficult to teach lung sound to the medical student because of the observer variability and the lack of objective recording in auscultation. Multimedia education has became available in many fields due to rapid development of computer and its software. So we made multimedia program to teach the lung sound and evaluated the effect of this program on the self study of the lung sound hy medical students. Method: We developed the multimedia title Auscultation of lung sound by integrating lung sounds, wave form display, radiographic findings and some explanations about various lung sounds including normal and abnormal lung sounds. Thirty students attending in the 2nd year of Medical school at the Hallym University was randomly divided into two groups. Each group studied on their own using either tape or multimedia title for one week. After the study, they were tested to describe the lung sound of real patients who were admitted to the Chun Cheon Sacred Heart Hospital. Multimedia group was asked to answer the questionnaire on multimedia title. Results: 1) Test score of auscultation on real patients The mean score of tape group and multimedia group was 1.20±1.08 and 1.54±0.74 respectively. But there was no significant difference between two groups (P=0.34). 2) Summary of questionnaire Twelve out of 15(80%) students answered that multimedia title helped them to understand the lung sound and three students (20%) answered that this program was very helpful. For the visual display of wave form, eight out of 15 (34%) students answered that it was helpful and three out of 15 (34%) students answered that it was very helpful. Eighty seven percent of the students answered that visual display of sound wave form helped them to understand the lung sound. Fourteen out of 15 students answered that multimedia program was interesting and provocative, All student answered that they will recommend this title to other colleagues. Conclusion: Even though there was no stastical significant difference between two self study methods but student of multimedia group showed narrow range of score than tape group. Answer to the questionnaire sup- ported the usefulness of multimedia for the self study of lung sound. Therefore we conclude that this program is helpful in the self-learninig of lung sound for medical students.
결핵균이 폐포대식세포의 기능에 미치는 영향에 관한 연구 -H37Ra 결핵균종에 의한 사람 및 백서 폐포대식세포의 Superoxide 생성의 변화-
김건열 ( Keon Youl Kim ),이계영 ( Kye Young Lee ),현인규 ( In Kyu Hyun ),김영환 ( Young Whan Kim ),한성구 ( Sung Koo Han ),심영수 ( Young Soo Shim ),한용철 ( Yong Chol Han ) 대한결핵 및 호흡기학회 1992 Tuberculosis and Respiratory Diseases Vol.39 No.6
폐결핵에서 객담 결핵균 중합효소 연쇄반응 검사의 누적 양성율
경태영(Tae Young Kyong),이준호(Jun Ho Lee),채경수(Gyeong Soo Chae),김동규(Dong Kyu Kim),모은경(Eun Kyung Mo),박명재(Myung Jae Park),이명구(Myung Goo Lee),현인규(In Gyu Hyun),남기형(Ki Hyung Nam),이경화(Kyung Wha Lee),정기석(Ki Suck J 대한내과학회 1998 대한내과학회지 Vol.55 No.6
N/A Objectives: The conventional methods such as smear or culture of Mycobacteria have been proved either low sensitivity and specificity or time-consuming. Polymerase chain reaction(PCR) is a rapid and sensitive alternative method to diagnose mycobacterial infection. We investigated the positive rate of sputum PCR for Mycobacterium tuberculosis by consecutive tests for its application in clinical practice. Methods: Sputum AFB smear, culture and serial AFR PCR test were performed in all patients who were suspected of pulmonary tuberculosis, Among them, 128 patients with positive sputum PCR test were enrolled from January 1996 through March 1997. The diagnostic criteria of pulmonary tuberculosis were sputum AFB smear positive, culture positive or pathologically proven granuloma. TB-CR TM kit (Bioneer, seoul, Korea), which amplifies insertion sequence(IS6110) of Mycobacterium tuberculosis complex, was used for sputum AFB PCR. Results: Of 128 patients, active pulmonary tuberculosis were 107 (male:74, female:33, mean age:48.9 year). Cumulative positive rate of sputum AFR PCR test was 89% at 1st test, 95% at 2nd test, 98% at 3rd test and 100% at 4th test. The sensitivity of sputum PCR, smear and culture was 98.0%(105/107), 85.0%(91/107) and 82.8%(77/107), respectively. The positive predictive value of sputum PCR was 83.6%(107/128). There were 21 patients who showed positive PCR test did not meet the diagnostic criteria of active tuberculosis. They had old tuberculosis with destroyed lung, history of anti-tuberculous medication(9/21), extrapulmonary tuberculosis (6/21) and other diseases(6/21). Conclusion: Sputum PCR test is a sensitive diagnostic tool in early diagnosis of pulmonary tuberculosis when it has been performed serially, we recommend at least 2 consecutive PCR test to achieve the sensitivity of 95%.
조영제에 의한 급성 전신성발진성농포증 환자에서 첩포시험으로 안전한 조영제 선별에 성공한 1예
김선형 ( Sun-hyung Kim ),이승연 ( Seung-youn Lee ),최영희 ( Young-hee Choi ),김철홍 ( Cheol-hong Kim ),현인규 ( In-kyu Hyun ),최정희 ( Jeong-hee Choi ) 대한천식알레르기학회(구 대한알레르기학회) 2018 Allergy Asthma & Respiratory Disease Vol.6 No.5
Acute generalized exanthematous pustulosis (AGEP) is rarely caused by radiocontrast media (RCM). The role of skin tests for the diagnosis and evaluation of cross-reactivity in a delayed type of RCM-induced hypersensitivity have yet to be determined. Here, we report a case of iodixanol-induced AGEP where we safely administered alternative RCM using patch tests. A 44-year-old woman had coronary artery angiography (CAG) for the evaluation of ischemic heart disease. She was on regular hemodialysis because of end-stage renal disease. She was given iodixanol (Visipaque) during CAG. Approximately 1 day after CAG, she developed AGEP. The patient was rehospitalized for CAG again after 1 year. We performed skin tests to choose safe alternative RCM. Intradermal tests with iodixanol, iohexol (Bonorex) and Iopamidol (Pamiray) showed negative responses. Patch tests showed a positive response to iodixanol, equivocal to iohexol, and negative to Iopamidol. We finally chose Iopamidol and performed CAG successfully without any adverse reaction. Patch tests may be a useful tool for the diagnosis and choice of safe alternatives in RCM-induced delayed-type hypersensitivity reactions such as AGEP. (Allergy Asthma Respir Dis 2018;6:270-273)