눈물흘림 환자에서 눈물주머니조영술상 완전폐쇄와 부분폐쇄 간의 실리콘관 삽입술의 성공률 비교

한지상,박인기,신재호,Ji Sang Han,In Ki Park,Jae Ho Shin 대한안과학회 2013 대한안과학회지 Vol.54 No.6

Purpose: This study compares the success rate of silicone tube intubation between nasolacrimal duct obstruction and stenosis according to dacryocystographic findings. Methods: A total of 115 patients who suffered from epiphora were divided into nasolacrimal duct obstruction and nasolacrimal duct stenosis according to dacryocystographic findings. Silicone tube intubation was performed on every patient. The success rate was estimated based on functional and anatomical success. Functional success was estimated by patient’s satisfaction with ‘good’ or ‘fair’ at the last visit, and anatomical success was estimated by decrease or normalization of tear meniscus height. Surgery success was defined when anatomical and functional successes were fulfilled. Results: Success rate of silicone tube intubation was 75.76% for patients with nasolacrimal duct obstruction based on dacryocystography, and 86.59% for patients with nasolacrimal duct stenosis based on dacryocystography; the difference was not statistically significant (Pearson chi-square test, p = 0.693). Conclusions: Silicone tube intubation can be considered as a primary treatment option for management of epiphora in nasolacrimal duct stenosis and obstruction.

식물의 프랙탈 디자인에 대한 3D 프린터 활용 STEAM 프로그램 개발 및 적용 효과

한지상,홍승호 한국초등과학교육학회 2018 한국초등과학교육학회 학술대회 Vol.74 No.-

3D 프린터를 활용한 나무 모형 프랙탈 구조 제작 STEAM 프로그램 개발 및 적용 효과

한지상,홍승호 서울교육대학교 초등교육연구원 2019 한국초등교육 Vol.30 No.1

Recent educational use of 3D printers can do mutual cooperation among students as well as advance the big thinking and creativity. So far, what is to consider about the programs studied, it needs to select activity-oriented and subject-oriented learning content but not only do printing with 3D printer for entertainment. It also requires to develop STEAM educational materials to actively participate in. The purpose of this study is to investigate the effect of 3D printer STEAM program on the science process skills, creative problem-solving ability and scientific attitude of elementary school students. For this purpose, the STEAM program was developed based on the STEAM education standard consisting of the situation presentation, the creative design, and the emotional experience so that the 3D printer and the fractal structure can be learned in a convergent manner and applied to the sixth grade students of elementary school. Study subjects had no experience for training of 3D printer or STEAM class. As a result, the creative problem-solving ability and scientific attitude of the group applying the program showed a significant improvement in the post-test than the pre-test. However, the science process skills are no significant difference between the post-test and the pre-test. So it needs to be further complemented the contents of the STEAM program for improvement of the science process skills. This means that the STEAM program using 3D printer developed in consideration of the characteristics of elementary students positively influenced the creative problem-solving ability and scientific attitude of elementary school students. In future, the STEAM programs on the theme of fractal structure and 3D printer need to be developed more variously. And it seems necessary to apply it to the elementary school field. 최근 3D 프린터의 교육적 활용은 학생들 상호 간 협동 작업도 할 수 있고, 고차원적인 사고와 창의 성을 신장시킬 수 있다. 지금까지 연구된 프로그램에서 고려해야 할 점은 학생들이 흥밋거리로 단지 3D 프린터로 프린팅 하는데 그치는 것이 아닌 활동 중심이면서 주제 중심의 학습 내용을 선정하고 적 극적으로 참여할 수 있는 STEAM 교육 자료를 개발하는 것이 필요하다. 이에 본 연구에서는 ‘Y' 반복 나무 모형 프랙탈 구조 제작을 위한 3D 프린터 활용 STEAM 프로그램을 개발하고 적용하여 초등학생 들의 과학 탐구 능력, 창의적 문제해결력 및 과학적 태도에 미치는 영향을 알아보고자 하였다. 이를 위 하여 3D 프린터와 프랙탈 구조를 융합적으로 학습할 수 있도록 상황 제시, 창의적 설계, 감성적 체험 으로 구성된 STEAM 교육 준거를 기반으로 STEAM 프로그램을 개발하여 초등학교 6학년 학생에게 적용하였다. 본 연구를 적용한 학생들은 3D 프린터나 STEAM 교육을 받아본 경험이 없었다. 적용 결 과, 프로그램을 적용한 집단의 창의적 문제해결력과 과학적 태도는 사전 검사보다 사후 검사에서 유의 미한 향상을 보였다. 하지만 과학 탐구 능력은 사전과 사후 검사에서 유의미한 차이가 없었으며 앞으 로 과학 탐구 능력을 더욱 더 향상시킬 수 있도록 프로그램의 내용을 보완할 필요가 있다. 이는 초등 학생들의 특성을 고려하여 개발한 3D 프린터 활용 STEAM 프로그램이 초등학생들의 창의적 문제해결 력 및 과학적 태도에 긍정적인 영향을 끼쳤음을 의미하며, 프랙탈 구조 및 3D 프린터를 주제로 한 STEAM 프로그램들이 더욱 다양하게 개발되어 초등학교 현장에 적용될 필요가 있어 보인다.

인터렉티브 모바일 컨텐츠

한지상(Jisang Han),최유미(Yoomi Choi) 한국애니메이션학회 2007 한국애니메이션학회 학술대회지 Vol.2007 No.11

의료 인공지능(AI)을 선호하는 경우: AI 의사에 대한 소비자 선호도에 대한 질병 낙인의 조절 역할

장이연,한지상 한국소비자학회 2023 소비자학연구 Vol.34 No.6

Consumer resistance or avoidance of going to the doctor is a widespread problem. While various industries are starting to think of solving this problem by using artificial intelligence (AI) doctors, there is little research in the marketing field on when and why consumers may be more likely to use medical AI. To fill this gap, our research focuses on disease type as a moderating factor, proposing an effective usage strategy. Study 1 provided initial evidence for the impact of disease type on consumers’ willingness to make an appointment with a doctor. The results revealed that consumers’ relative preference for AI doctors increased when they had symptoms of a stigmatized (vs. non-stigmatized) disease. Study 2 provided evidence for our hypothesized role of shame as the underlying mechanism of our proposed effect. That is, the difference in relative preference for a human versus AI doctor in response to a stigmatized (vs. non-stigmatized disease) was mediated by the amount of shame consumers expected to feel during the appointment. The findings contribute to research on consumer healthcare and consumer response to medical AI and provide practical implications for hospitals, healthcare companies, and society at large that are looking to harness the potential of AI technology and help patients.

시신경을 침범한 밀러피셔증후군

박인기,문상웅,한지상,신재호,In Ki Park,Sang Woong Moon,Ji Sang Han,Jae Ho Shin 대한안과학회 2010 대한안과학회지 Vol.51 No.12

Purpose: To report an extremely rare case of optic nerve involvement in Miller-Fisher syndrome. Case Summary: A 74-year-old woman presented to our clinic with decreased visual acuity in both eyes. Such symptoms started 1 month prior to her visit, after sudden onset of left-side motor power weakness and dysphasia. Following the initial symptoms, our patient consecutively experienced worsening dysphagia, ptosis, and lateral gaze limitation. We confirmed the diagnosis as Miller Fischer syndrome with a positive anti-GQ1b antibody serology. She received immunoglobulin treatment for 5 days in other departement. She visited our clinic due to continuing diplopia, decrease of visual acuity and gait disturbance. On initial examination, the corrected visual acuity was 0.5 in both eyes. Ptosis of both eyelids, esodeviation, limitation in ocular movement was noted. The fundoscopic examinations revealed relatively pale optic disc. There was decrease in color vision in both eyes. The visual evoked potential test showed low amplitude and delayed latency in P100 wave in both eyes. Two months after her initial visit to our department her symptoms started to improve, and after 4 months all the initial problems resolved completely and her corrected visual acuity checked out to be 0.8 in both eyes and VEP abnormality was recovered. Conclusions: It is extremely uncommon for Miller Fisher syndrome to involve the optic nerve. We present such a case of a 74-year-old woman whose symptoms improved 4 months after its first attack with treatment. J Korean Ophthalmol Soc 2010;51(12):1676-1680

성형안과 질환과 눈물막 내 기질금속단백질분해효소 9와의 연관성 분석

최완규,박정우,한지상 대한안과학회 2023 대한안과학회지 Vol.64 No.10

목적: 성형안과 외래로 내원하는 다양한 환자에서 눈물막 matrix metalloproteinases 9 (MMP-9) 성분 분석을 통해 성형안과 질환의진단과의 연관성에 대해 알아보고자 하였다. 대상과 방법: 안구 불편감을 호소하며 성형안과 외래로 내원한 1,703명 환자의 1,703안에 대한 MMP-9 면역분석키트의 결과를 후향적으로 분석하였고 최종 성형안과 진단에 따른 MMP-9 결과의 양성률에 대해 분석하였다. 결과: 총 1,533안 중 1,126안에서 MMP-9 면역분석키트검사 양성을 보였다. 환자의 성별과 나이는 MMP-9 발현과 유의미한 상관관계를 보이지 않았다. 169안의 갑상샘눈병증 환자 중 120안, 161안의 비루관폐쇄 환자 중 145안, 375안의 비루관협착 환자 중 282안, 238안의 안검내반 환자 중 190안, 23안의 안검외반 환자 중 19안에서 MMP-9 양성 결과를 보였다. 결론: MMP-9 면역분석키트검사는 비침습적이고, 쉽고 빠른 검사 방법으로 다양한 성형안과 질환을 가진 환자들의 눈물막에서MMP-9 증가 소견을 보인다. 성형안과 외래로 내원하는 환자에서 MMP-9 검사 결과는 진단 및 치료 방향 결정에 도움을 줄 수 있다. Purpose: We assessed the association between the results of tear film-based matrix metalloproteinases 9 (MMP-9) immunoassay and the diagnosis of patients who visited an oculoplastic outpatient clinic. Methods: We conducted a retrospective analysis of the MMP-9 immunoassay results in 1,703 eyes from 1,703 patients who presented with ocular discomfort at an oculoplastic outpatient clinic. The MMP-9 immunoassay results were analyzed in correlation with the final oculoplastic diagnosis of the patients. Results: In total, 1,126 of 1,533 eyes demonstrated positive expression of MMP-9. No statistically significant differences were observed in MMP-9 expression based on sex (p = 0.107) and age (p = 0.510). Furthermore, 120 of 169 eyes with thyroid eye disease (71.0%, p < 0.001), 145 of 161 eyes with nasolacrimal duct obstruction (90.1%, p < 0.001), 282 of 375 eyes with nasolacrimal duct stenosis (75.2%, p < 0.001), 190 of 238 eyes with entropion (79.8%, p < 0.001), 19 of 23 eyes with ectropion (82.6%, p < 0.001), and 370 of 567 eyes with dry eye syndrome (65.3%, p < 0.001) exhibited positive MMP-9 expression. Conclusions: The MMP-9 immunoassay is a noninvasive, convenient, and rapid test that evaluates ocular surface inflammation. Most patients with oculoplastic diseases exhibit positive MMP-9 expression. These findings provide valuable information for guiding diagnostic and management decisions in patients with oculoplastic conditions.

유두절제술과 양막이식을 이용한 난치성 봄철각결막염의 치료 1예

송희준,권진영,한지상,양지호,권지원 대한안과학회 2017 대한안과학회지 Vol.58 No.8

목적: 약물치료에 반응하지 않는 난치성 봄철각결막염 환자에서 거대유두절제술과 상안검판 양막이식술을 동시에 시행하여 성공적으로 치료한 1예를 보고하고자 한다. 증례요약: 20세 여자 환자가 14세부터 호전과 악화를 반복하는 양안의 봄철각결막염으로 내원하였다. 점안 치료를 시행하였으나 호전되지 않았고 상안검판에 다수의 거대유두와 윤부종창이 생성되며 작열감, 소양증, 이물감 등의 증상이 진행되었다. 좌안 상안검판거대유두를 수술적으로 제거 후 양막을 절제부위에 이식하였고, 한 달 뒤 같은 방법으로 우안 거대유두 절제술을 시행하였다. 환자의 증상은 호전되었으며 6개월이 지난 현재 환자는 재발이나 별다른 합병증 없이 경과 관찰 중이다. 결론: 난치성 봄철각결막염에서 거대유두절제술과 양막이식술을 동시에 시행하는 것은 수술 후 재발률을 낮추고 증상을 호전시키는 데 효과적인 치료방법으로 생각된다. Purpose: To report a successful case of intractable vernal keratoconjunctivitis treated by papillectomy and amniotic membrane transplantation. Case summary: A 20-year-old female patient presented with repeated vernal keratoconjunctivitis in both eyes since the age of 14. Despite medical therapy, she developed severe itching, burning and foreign body sensations, and limbal nodules with mutiple giant papillae of the upper tarsal plate. Surgical resection of the giant papillae and amniotic membrane transplantation in her left eye was performed. One month later, the same procedure was performed in her right eye. The patient’s symptoms then improved. Neither recurrence nor serious complication were observed during the 6 months follow up period after surgery. Conclusions: In intractable vernal keratoconjunctivitis, papillectomy with amniotic membrane transplantation may potentially be a good treatment option for better clinical outcome and low recurrence rates.

Seismic performance evaluation of agricultural reservoir embankment based on overtopping prevention structures installation

윤보라,류정현,한지상,이달원 충남대학교 농업과학연구소 2023 Korean Journal of Agricultural Science Vol.50 No.3

In this study, three types of structures–stepped gabion retaining walls, vertical gabion retaining walls, and parapets–were installed on the dam floor crest to prevent the overflow of deteriorative homogeneous reservoirs. The acceleration response, displacement behavior, and pore water pressure ratio behavior were compared and evaluated using shaking-table model tests. The experimental conditions were set to 0.154 g in consideration of the domestic standard and the seismic acceleration range according to the magnitude of the earthquake, and the input waveform was applied with Pohang, Gongen, and artificial earthquake waves. The acceleration response according to the design ground acceleration increased as the height of the embankment increased, and the observed value were larger in the range of 1.1 to 2.1 times the input acceleration for all structures. The horizontal and vertical displacements exhibited maximum values on the upstream slope, and the embankment was evaluated as stable and included within the allowable range for all waveforms. The settlement ratio considering the similarity law exhibited the least change in the case of the parapet structure. The amplification ratio was 1.1 to 1.5 times in all structures, with the largest observed in the dam crest. The maximum excess pore water pressure ratio was in the range of 0.010 - 0.021, and the liquefaction evaluation standard was within 1.0, which was considered very stable.

Analysis of the Retinal Nerve Fiber Layer Thickness in Alzheimer Disease and Mild Cognitive Impairment

권진영,양지호,한지상,김도균 대한안과학회 2017 Korean Journal of Ophthalmology Vol.31 No.6

Purpose: To compare the retinal nerve fiber layer (RNFL) as well as the macula volume and thickness in theeyes of age-matched healthy controls with no cognitive disabilities with those of elderly people with mild cognitiveimpairment (MCI) or Alzheimer disease (AD). We used optical coherence tomography (OCT) to determinethe effectiveness of the above quantities for early diagnosis of MCI or AD. Methods: Ninety eyes were considered in this study, split between 30 normal eyes, 30 eyes from patients withMCI, and 30eyes from patients with AD. All subjects underwent ophthalmologic and cognitive examinations,and measurements of the RNFL thickness as well as macular volume and thickness were taken for all patientsusing OCT. Results: The mean RNFL thickness upon OCT was significantly thinner in the AD group than in the MCI group(p = 0.01). The RNFL was thinner in the superior quadrant in patients with AD when compared to the healthycontrols (p = 0.03). The RNFL thicknesses in the inferior, nasal, and temporal quadrants did not differ significantlybetween the groups. Measurements in the 12 clock-hour zones revealed that zone 11 had a significantlythinner RNFL in the AD group as compared with the healthy control group (p = 0.02). In zone 2, the MCI grouphad a significantly thinner RNFL than the AD group (p = 0.03). Conclusions: Our OCT findings revealed a neuroanatomic difference in the RNFL thickness among the threegroups, i.e., the AD, MCI, and healthy control groups. This suggests that a change in average RNFL thicknesscould be a meaningful index for diagnosing early AD.