단순 유방촬영술상 동반되는 종괴 없이 보이는 군집성 미세석회화 : 양성과 악성의 예측

한윤희,도영수,조병제,한헌,최연현,박정미,한부경,오훈일,김기환,진수일,Han, Yoon-Hee,Do, Young-Soo,Cho, Byung-Jae,Han, Heon,Choi, Yeun-Hyeun,Park, Jung-Mi,Han, Boo-Kyung,Oh, Hoon-Il,Kim, Ki-Hwan,Chin, Soo-Yil 대한영상의학회 1996 대한영상의학회지 Vol.35 No.5

Purpose : The purpose of this study is to evaluate the accuracy of differentiation between benign andmalignant clustered microcalcifications without mass on mammogram. Material and Methodes : Fourty six mammogramsof 44 patients showing clustered microcalcifications without mass were interpreted blindly by five independentobservers majoring in breast imaging from different institutions. Twenty two were malignant (10 infiltratingductal carcinomas, 12 intraductal carcinomas) and 24 were benign (all fibrocystic disease). The observers judgebenignancy or malignancy of microcalcifications. The authors assess the accuracy of differential diagnosis ofclustered microcalcifications. Result : Of 24 cases proved benign microcalcifications, five radiologists correctlyinterpreted 20 on average as benign and of malignant 22 cases, 16 on average were correctly interpreted asmalignant. The diagnostic accuracy of malignant microcalcifications was 71.8% on average(63.6%~81.8%) and thediagnostic accuracy for benign microcalcifications was 83% on average(71%~ 92%). It was 9 among total 46 casesthat were misinterpreted by more than three radiologists. Among these 9 cases, malignant microcalcifications thathad been misinterpreted as benign were seven, benign microcalcifications misinterpreted as malignant were two.Conclusion : The diagnostic accuracy of clustered malignant microcalcifications(71.8%) without mass on mammogramwas lower than that of benign microcalcifications(83.3%). So, in case of suspected malignant microcalcification onmammogram, it is preferable that along with magnification view, histopathologic confirmation by core biopsy mustbe obtained.

L형 주물응고에 (鑄物凝固) 대한 Computer Simulation

한윤희,김명한,김동옥 ( Yoon Hee Han,Myung Han Kim,Dong Ok Kim ) 한국주조공학회 1985 한국주조공학회지 Vol.5 No.2

The most desirable method for the solution of solidification problems in castings must be the one which combines accuracy, simplicity, and low computer usage cost. The purpose of the present study is to develop a method which includes all these advantages. The purpose of the present research was approached by the introduction of two methods: (1) A pour-out test, employed with very high purity aluminum, for the purpose of obtaining accurate solidification data in L-sections; and (2) an numerical technique, using the cubic spline function for defining solidification curves.

넙치(Paralichthys olivaceus) 혈청단백질의 이차원전기영동분석 조건확립

한윤희,남보혜,감영옥,김우진,공희정,이상준,최태진,Han, Yoon Hee,Nam, Bo-Hye,Kim, Young-Ok,Kim, Woo Jin,Kong, Hee Jeong,Lee, Sang Jun,Choi, Tae-Jin 한국해양바이오학회 2007 한국해양바이오학회지 Vol.2 No.1

Flounder is one of the major aquacultured fish and of an economically important item in Korean fisheries. Recently, there are trends of research worldwide that aim to analyze and characterize a whole genome or a whole proteome of interesting species. The data are utilized for the understanding and development of preventive and curative technologies for the serious diseases. However, there are very limited information of proteome for marine organisms, we optimized first the conditions for two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) with serum form a marine fish, flounder (Paralichthys olivaceus). A pre-treatment of serum and an optimization of protein concentration analyzed were surveyed for enhancing the separation for proteins. A statistical analysis was performed on the overall 1,820 protein spots to overcome the variability among individual fishes. 넙치의 혈청 단백질체를 연구하기 위해 본 연구에서는 이차원전기영동 분석 시의 기본조건을 확립하였다. 넙치의 혈청단백질을 이차원전기영동 법으로 분석하기 위해서는 TCA 침전을 이용하여 혈청 내에 고농도로 존재하는 이온물질을 제거하는 전처리과 정이 반드시 요구되었다. 또한 분석 단백질의 농도는 $30{\mu}g$이 적당하였다. 넙치 10개체의 혈청단백질을 이용하여 총 51회의 이차원전기영동을 수행한 결과 1,8207개의 단백질로 이루어진 넙치 혈청단백질 표준 지도를 작성할 수 있었다.

순아연주물응고에 (純亞鉛鑄物凝固) 있어서 Fin 효과에 관한 연구

한윤희,김명한,김동옥 ( Yoon Hee Han,Myung Han Kim,Dong Ok Kim ) 한국주조공학회 1985 한국주조공학회지 Vol.5 No.4

Thin sections in castings solidify faster than thick sections. Solidification rates increase because of an increase in heat transfer from molten meltals to molds through these solidified thin sections. The cooling fin effect in pure zinc casting was studied about the solidification time, superheat, and fin size by adopting the pourout test. The following results could be obtained from the study: (1) The fin effect could be represented by the effective cooling surface area (A_f/S) increased. (2) The fin effect could be obtained as functions of solidification time, superheat, and fin size.

근적외선 분광분석을 이용한 종이기록물의 비파괴 특성평가 연구

한윤희(Yoon Hee Han),신용민(Yong Min Shin),박성배(Soung Be Park),남성운(Sung Un Nam),김효진(Hyo Jin Kim) 한국분석과학회 2010 분석과학 Vol.23 No.3

Image analysis에 의한 한지와 화지의 섬유 배향성 연구

한윤희(Yoon-Hee Han),에노마에 토시하루(Toshiharu Enomae),이소가이 아키라(Akira Isogai) 한국펄프·종이공학회 2006 한국펄프·종이공학회 학술발표논문집 Vol.- No.-

조선 초 피로인 송환에 관한 한 연구 - 나카무라 히데다카(中村栄孝)의 <해구(海寇)에서 해상(海商, =평화로운 통호자)으로의 전환>설을 중심으로 -

한윤희(Han, Yoon-hee) 국방부 군사편찬연구소 2021 군사 Vol.- No.118

Hidedaka Nakamura, a pioneer in the pre-modern Korean-Japanese relations history, believes that "the number of Japanese people coming and going with Chosun gradually increased through the repatriation of captives(piroin), and eventually the position of pirates(waegu) turned into the status of merchants." This means that pirates(waegu) and merchants are different. However, it was recently revealed that Nakamura was an imperial oriented historian. Therefore, it was judged that this argument also needed to be reviewed, whether or not it was affected by such ideological influence. In this paper, this paper is named as the theory of Hidedaka Nakamura"s "transition from pirates(waegu) to merchants“, and examined the range of the period between King Taejo and King Taejong in terms of paper. And in this paper, we have focused on the following three things. First, did the invasion of weagu decrease as the number of Japanese people coming and going to Chosun increased? Second, were weagu and merchants different from each other? Third, what is the significance of the repatriation of captives(piroin) in early Chosun? As a result of the review, the invasion of weagu also increased sharply at the time when Japanese people coming to Chosun increased rapidly. Since then, the pirates were intermittent, but continued to invade Chosun. In addition, in China at the same time as the Chosun Taejo-Taejong year, pirates were invading on a large scale almost every year. In other words, the pirates who invaded Chosun moved to China. From the historical records, it can be seen that pirates invading China are no different from beings invading Joseon. When they encountered a situation in which they were defended, they acted as merchants, and in the opposite situation, they returned to the position of pirates. In other words, they always had two aspects of a pirate and a merchant, just like the front and back sides of a coin, only different aspects depending on the region and situation. Therefore, it seems that the repatriation of captives(piroin) in the early Chosun period did not convert pirates into merchants, but ①moved the invading area, ②changed their existence according to the region and situation, such as "pirates" in China and "merchant" in Chosun.

대두단백가수분해물이 흰쥐의 지질대사와 항산화에 미치는 영향

한윤희(Han Yoon Hee),박상규(Park Sang Kyu),김혜영(Kim Hye Young) 韓國營養學會 2008 Journal of Nutrition and Health Vol.41 No.2

본 연구는 대두단백가수분해물의 섭취가 소화흡수율, 지질대사 및 항산화에 미치는 영향을 살펴보고자 흰쥐를 카제인, 분리대두단백 (ISP) 또는 대두단백가수분해물 (서리태단백분해물 (SH), 수용성단백분해물 (SS) 또는 불용 성단백분해물 (IS)군으로 나누어 4주간 사육한 후 생리활성의 변화를 살펴보았으며, 그 결과를 요약하면 다음과 같다. 1) 지질소화흡수율은 실험 1주차에서 분리대두단백군 (ISP군)이 다른 군보다 유의적으로 낮았다. 불용성가수분 해물군 (IS군)은 실험 4주차에서 다른 군들보다 콜레스테롤의 소화흡수율이 낮은 경향이었다. 2) 혈액 중성지방은 불용성가수분해물군 (IS군)이 카제인군보다 유의적으로 낮았고, 서리태가수분해물군과 ISP군도 낮은 경향이었다. 총 콜레스테롤도 중성지방과 마찬가지로 불용성가수분해물군이 가장 낮았고 다른 대두가수분 해물군들과 ISP군도 카제인군보다 낮은 경향이었다. 대두 가수분해물군들이 카제인군보다 HDL-cholesterol은 높이고, LDL-cholsterol은 낮추어서 동맥경화지수는 불용성, 수용성, 서리태가수분해물의 순으로 낮았다. 3) 총항산화력은 군 간에 유의적인 차이가 없었으나 서리태가수분해물군 (SH군)이 다른 군들에 비해 높은 경향이었다. 간의 항산화효소활성은 각 군 간에 유의적인 차이는 없었으나 서리태가수분해물군의 superoxide dismutase, glutathione peroxidase 및 catalase 활성이 카제인군과 다른 실험군들에 비해 높은 경향이었다. 결론적으로, 대두단백가수분해물군들은 카제인군보다 혈액 중성지질, 총콜레스테롤, LDL-cholesterol과 동맥경화 지표 (AD를 낮추어서 심혈관질환예방에 바람직한 것으로 나타났는데, 이러한 효과는 특히 불용성단백가수분해물군에서 뛰어났다. 한편, 항산화활성의 경우 총항산화력과 항산화효소활성이 서리태기수분해물군에서 높은 경향으로 나타나 앞으로 서리태의 항산화 효과의 원인물질을 규명하고 분리추출하는 등의 연구를 통해 우리나라의 전통 콩의 우수한 면모를 밝히는 연구가 더 필요하다고 사료된다. This study was conducted to investigate the effect of soy protein hydrolyzate on lipid metabolism and antioxidant activity in the rat. Thirty-eight male rats of Sprague-Dawley strain were divided into five groups: casein, isolated soy protein (ISP), seoritae protein hydrolyzate (SH), soluble soy protein hydrolyzate (SS), and insoluble soy protein hydrolyzate (IS). The control diet (casein group) contained 20% casein protein and experimental diet contained 10% casein and 10% isolated soy-protein or soy-protein hydrolyzate. Fecal lipid content was increased and lipid apparent absorption rate was decreased significantly by the ISP group at the first week of experimental period. Blood triglyceride, total cholesterol, LDL-cholesterol and atherogenic index (AI) were decreased by soy protein hydrolyzate groups than casein group. Liver total lipid, triglyceride and cholesterol were not different among groups, but showed decreasing tendencies in soyprotein hydrolyzate groups. The lipid lowering effect was prominent in the IS group among soy protein hydrolyzate groups. Total antioxidant activity showed increasing tendency in the seoritae hydrolyzate group. Liver superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase activities also showed higher tendencies in the seoritae hydrolyzate group than other groups. In conclusion, insoluble soyprotein hydrolyzate was more effective in lowering body lipids and seoritae hydrolyzate had higher antioxidant capacity among soy protein hydroly-zates. (Korean J Nutr 2008; 41(2): 119~126)

국보 승정원일기의 지질 분석 및 초지기술에 관한 특성

한윤희(Yoon-Hee Han) 한국펄프·종이공학회 2023 한국펄프·종이공학회 학술발표논문집 Vol.2023 No.10

여성 결혼 이민자의 한국 식생활 적응요인 및 식행동 연구

한윤희 ( Yoon Hee Han ),신원선 ( Weon Sun Shin ),김지나 ( Ji Na Kim ) 국제비교한국학회 2011 비교한국학 Comparative Korean Studies Vol.19 No.1

This study aims to guide international families to obtain ideal dietary life by finding out female marriage immigrants` eating habit, dietary behaviour, and the influential factors in their experience of adjusting to a new food culture. Most female marriage immigrants who participated in this survey were, on average, 29.37 years old and have lived in Korea less than one year. Majority of them (43.8%) have graduated from high school as well. The time it took female marriage immigrant participants to get used to Korean food was between 1~3months, depending on the length of residence in Korea, which brought different result(p<0.05), participants who have been living in Korea less than 7 years adjusted to Korean food faster than those who have been living in Korea more than 7 years. For participants who have tried Korean food before they came to Korea showed higher level of satisfaction with Korean food than those who didn`t (p<0.05). Most participants tried Korean food through Korean restaurants in their home countries; it showed how popular Korean food became in other countries. Most participants lacked confidence with cooking Korean food and showed strong desire to learn how to cook Korean food. Preferred Korean dish to learn varied over race(p<0.05) Chinese participants wanted to learn how to cook Jun-Gol (beef with vegetables cooked in casserole)and a pot stew(33.3%), Vietnamese participants chose Kimchi dish(37.1%), Uzbek participants picked wild vegetable and seasoned green(50.0%) and Filipina chose all of above dishes(26.7%). When choosing their favourite Korean dish among dog meat, Uk-Gae-Jang(soup of chopped beef with various condiments), spicy fish soup, minced raw beef, and fruits, the results were differ over participant`s nationalities(p<0.05), original food culture and their race played important roles.