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XML 데이타를 위한 객체지향 데이터베이스 스키마 및 질의 처리
정태선,박상원,한상영,김형주,Jeong, Tae-Seon,Park, Sang-Won,Han, Sang-Yeong,Kim, Hyeong-Ju 한국정보과학회 2002 정보과학회논문지 : 데이타베이스 Vol.29 No.2
As XML has become an emerging standard for information exchange on the World Wide Web it has gained attention in database communities to extract information from XML seen as a database model. Recently, many researchers have addressed the problem of storing XML data and processing XML queries using traditional database engines. Here, most of them have used relational database systems. In this paper, we show that OODBSs can be another solution. Our technique generates an OODB schema from DTDs and processes XML queries, Especially, we show that the semi-structural part of XML data can be represented by the 'inheritance' and that this can be used to improve query processing. XML이 웹상에서 정보 교환의 표준으로 채택되면서 XML을 데이타베이스의 데이타로 보고 정보를 추출하는 분야가 주목받고 있다. 특히 최근에는 기존의 DBMS 시스템에 XML 데이타를 저장하여 기존의 DB 엔진으로 XML 질의를 처리하는 분야가 많이 연구되고 있다. 이때 주로 관계형 DBMS를 사용하는 연구가 많이 시도되고 있다. 본 연구에서는 객체 지향 데이타베이스 시스템이 XML 데이타를 저장하고 질의를 처리하는 또 하나의 해법이 될 수 있음을 보인다. 제안하는 방법은 XML의 DTD로부터 OODB의 클래스를 생성하고 이 클래스에 대하여 XML 질의를 수행한다. 특히, XML 데이타의 비정형적인 성질이 OO 모델의 계승(inheritance)을 이용하여 표현되어 질의 처리시에 유용하게 사용될 수 있음을 보인다.
Von Willebrand factor 이상을 보이는 Heyde 증후군
이태영 ( Lee Tae Yeong ),한상영 ( Han Sang Yeong ),문성훈 ( Mun Seong Hun ),장채령 ( Jang Chae Lyeong ),장진석 ( Jang Jin Seog ),박미경 ( Park Mi Gyeong ),이종훈 ( Lee Jong Hun ),노명환 ( No Myeong Hwan ),신우원 ( Sin U Won ),최 대한소화기학회 2004 대한소화기학회지 Vol.43 No.2
A 68-year-old woman with known severe aortic stenosis was admitted to the hospital because of hematochezia and dizziness. She had received several blood transfusions over the preceding 3 years and undergone right hemicolectomy 2 years ago for severe lower gastrointestinal bleeding. Postoperative histology revealed angiodysplasia involving the ascending colon. After the hemicolectomy, she continued to have hematochezia and anemia and required additional blood transfusions for anemia. During this admission, platelet count, activated partial- thromboplastin time, von Willebrand factor antigen, and von Willebrand factor ristocetin cofactor were normal. She had a severe deficiency of high-molecular-weight multimers of von Willebrand factor. Colonoscopy showed angiodysplasia in the transverse colon at this time. Successful coagulation of the bleeding angiodysplasia was achieved by argon plasma coagulator. No additional bleeding was observed thereafter. We report a case of Heyde`s syndrome with abnormal von Willebrand factor in a patient who presented with intestinal angiodysplasia and aortic stenosis. (Korean J Gastroenterol 2004; 43:133-136)
만성 위염에서 Helicobacter Pylori 에 대한 간편 검사법들의 진단을 비교
손지원(Ji Won Son),한상영(Sang Young Han),최석렬(Seok Reyol Choi),신우원(Woo Won Shin),홍숙희(Sook Hee Hong),한진영(Jin Yeong Han) 대한내과학회 1994 대한내과학회지 Vol.46 No.1
N/A Background: Helicobacter pylori has been implicated in the pathogenesis of chronic active gastritis, peptic ulcer disease, gastric cancer. The rapid identification of this organism may depend upon histologic diagnosis, because culture methods are complex and require a minimum of seven days in to identifying a negative specimen. The purpose of this study was to determine which simple test u to identify this organism was the most cost-effective and easiest to perform and interpret on a routine basis. Methods: The authors evaluated the use of rapid urease test (CLO test(R)), Bio-Rad G.A.P. IgG and 1gM test to detect Helicobacter pylori in 80 patients with chronic gastritis, Results: Sixty patients (75%) had H.pylori identifiable in Giemsa stains, Also, sixty patients (75%) had positive rapid urease tests, sixty eight patients (85%) had positive serum IgG tests, and fifty two patients had positive serum IgM tests. The sensitivities of the methods were as follows: 93% for the rapid urease test, 90g for the serum IgG test, and 63% for the serum IgM test. The specificities of the methods were as follows: 80% for the rapid urease test, 35% for the serum IgG test, and 15% for the serum IgM test. The accuracies of the methods were as follows: 90% for the rapid urease test, 76% for the serum IgG test, and 50% for the serum IgM test, Conclusion: The rapid urease test used in this study is a useful, highly specific screening test; That the serum IgG test has limited specificity.
간세포암 환자의 고주파 열치료후 종양괴사부위의 위축정도: 경계면 재발과의 상관관계 및 위축에 영향을 미치는 인자들
오종영,남경진,최종철,윤성국,박병호,이기남,최순섭,한상영,신우원,O, Jong-Yeong,Nam, Gyeong-Jin,Choe, Jong-Cheol,Yun, Seong-Guk,Park, Byeong-Ho,Lee, Gi-Nam,Choe, Sun-Seop,Han, Sang-Yeong,Sin, U-Won 대한영상의학회 2002 대한영상의학회지 Vol.46 No.6
목적:간세포암의 고주파 열치료후 6개월 내에 잔류종양 및 새 원발성 재발이 없었던 예에서 6개월 추적 전산화단층촬영(CT)과 치료직후 CT를 비교하여 괴사부위의 위축정도와 이에 영향을 미치는 인자에 대해 알아보았으며,1년이상의 추적 기간동안 위축정도와 경계면 재발과의 연관성을 알고자하였다. 대상과 방법:1999년 5월부터 2000년 7월까지 5 cm 이하의 간세포암으로 다른 치료없이 고 주파 치료만을 하고 6개월내에 재발이 없었던 54명(62결절)의 환자를 대상으로 후향적으로 분석하였다.고주파 치료직후 시행한 CT와 6개월 추적 CT에서 괴사부위의 부피를 서로 비교하여 위축정도를 50%이하(Group I),50-80%(Group II),그리고 80%이상(Group III)의 3군으 로 임의로 나누어 분류하였다.괴사부위의 부피감소에 영향을 줄 수 있는 인자들로는 간기능 보유상태(Child-Pugh 분류),시술전 CT상 종양의 혈관성,종양의 크기,고주파 치료의 횟수, 치료후 종양 괴사부위의 변연부 모양,종양주위 혈관의 유무 그리고 괴사부위내 공기방울유무등을 비교하고 Fisher ’s Exact Test로 이들의 통계적 유의성을 검정하였다.또한 1년이상의 추적 검사를 통하여 괴사부위의 위축정도와 경계면 재발과의 상관관계에 대해서도 알아보았다. 결과:6개월 추적 CT상 종양 괴사부위는 치료직후 CT에 비해 평균 72%감소되었으며 Group I,II,III 인 경우가 각각 14예,13예,35예였다.치료전 CT상 종양주위에 혈관이 인접한 경우 는 각각 12예(86%),3예(23%),11예(31%)로 통계적으로 유의하였으며 (p=0.001),치료직 후 CT상 괴사부위내 공기방울은 각각 Group I,II,III의 2예(14%),5예(38%),24예(69%)에 서 관찰되어 역시 통계학적으로 유의한 소견을 보였다 (p <0.05).1년 이상의 추적기간중 경 계면 재발이 있었던 경우는 Group I이 4예(29%),Group II가 2예(15%),Group III가 2예(6%) 로 통계적으로 유의하였다 (p <0.05). 결론:치료전 CT상 종양 주위에 인접한 혈관이 없는 경우 그리고 치료직후 CT상 괴사부위 내에 공기방울이 보이는 경우에 괴사부위의 위축이 더 많이 진행되었다.또한 괴사부위의 위축이 많이 될수록 경계면 국소재발의 빈도는 감소하였다. 구되었음. Purpose: To compare the CT findings of hepatocellular carcinomas (HCCs) immediately after radiofrequency (RF) ablation with those obtained at six months' follow-up, to analyse the relationship between degree of shrinkage of a necrotic lesion and marginal recurrence, and to evaluate the factors influencing shrinkage. Materials and Methods: We retrospectively evaluated 54 patients with 62 HCCs who underwent only RF ablation between May 1999 and July 2000. For six months after ablation, all had been free from marginal recurrence ad new-growth tumors. The findings of six-month follow-up CT were compared with those obtained immediately after RF ablation, and the volume of each necrotic lesion was calculated and compared. In terms of degree of shrinkage, tumors were classified as belonging to either group I (below 50%), group II (50-80%) or group III (above 80%). Each tumor was analysed in terms of its Child-Pugh classification, vascularity at CT, size, treatment details, the post-ablation appearance of its margins, and the presence, during necrosis, of peritumoral vessles and air bubbles. For statistical evaluation, Fisher's exact test was used. Shrinkage after ablation was correlated to marginal recurrence during a period of more than one year. Results: The Follow-up CT at six months showed that since immediately after ablation, necrotic lesions had shrunk by an average of 72%. Peritumoral vessels were seen in 12 of 14 cases in group I (86%), three of 13 in cases of group II (23%), and 11 of 35 in group III (31%)(p=0.001). Immediate CT revealed the presence of air bubbles in two cases in group I (14%), five in group II (38%), and 24 in group III (69%)(p<0.05). At follow-up CT performed during a period of more than one year, marginal recurrence was noted in four cases in group I, two in group II and two in group III (p<0.05). Conclusion: When a necrotic lesion contains no peritumoral vessels but does contain air bubbles, the degree of post-RFablation shrinkage increases. The greater the shrinkage, the less the marginal recurrence rate.
홍숙희(Sook Hee Hong),최석렬(Seok Reyol Choi),김두형(Du Hyeong Kim),한상영(Sang Young Han),노명환(Myung Hwan Roh),허기영(Gi Yeong Huh),신우원(Woo Won Shin),김종성(Jong Seong Kim) 대한소화기학회 1997 대한소화기학회지 Vol.29 No.5
N/A Background/Aims: This study is aimed to observe the expression of GST-z in colorectal adenomas and adenocarcinomas according to the risk and prognostic factors, and investigate the role during carcinogenesis and the possibility of clinical application as a tumor marker of colorectal neoplasm, in cornparision with the expression of p53 protein and CEA. Methods: Immuno- histochemical stain was performed in 15 cases of normal colon, 31 adenomas and 63 adenocarci- nomas. Results: The incidence of GST- expression was higher in adenocarcinoma (95.2%) than normal colon(40%), adenoma(87.1%) and adjacent norrnal mucosa to adenocarcinoma(63.5%) and the degree of the expression was also significantly different among them. In adenomas, the higher the degree of dysplasia, the higher the expression of GST-z. In adenocarcinomas, the expression was significantly decreased in relation with progression to lower histologic grade. The incidence of p53 expression was higher in adenocarcinomas(54.0%) than normal colon(0%), adenoma(25.8%) and adjacent normal mucosa to adenocarcinoma(0%) and the degree of the expression was also significantly different among them. In adenomas, the higher the degree of dysplasia, the higher the expression of p53. In adenocarcinoma, there was no sifnificant difference in relation with the histologic grade and stage. The incidence of CEA expression was higher in adenocarcinoma (96.8%) than normal colon(33.3%), adenoma(64.5%) and adjacent normal mucosa to adenocarci- norna(95.2%) and the degree of the expression was also significantly different among them. In adenomas, there was no significant difference in relation with size, amount of villous component and degree of dysplasia. In adenocarcinomas, the expression was increased in relation with progression to higher stage. The incidence of intense co-expression of GST-z and p53 in adenocarcinoma showed a tendency to be increasing in relation with progression to higher stage. But there was no statistically significant. Conclusions: It has been found from the above results that the expression of GST-z is progressively increased during colorectal carcinogenesiser. (Korean J Gastroenterol 1997;29:632-644)