영상 분석장치를 이용한 골 흑화도의 정량적 평가에 관한 연구

최원재,김재덕,Choi Won-Jae,Kim Jae-Duk 대한영상치의학회 1995 Imaging Science in Dentistry Vol.25 No.2

This study was performed to develop and evaluate the method to detect Quantitatively the serial changes in the size of artificial lesion in the spongious bone by automatic color image analyzer. 15 intraoral radiograms taken before and after endodontic treatment of 5 cases were used for contour line analysis. 30 intraoral radiograms taken by geometrically standardized apparatus before and after serially the formation of artificial lesions of 0.80, 1.20, 1.75, 2.00mm in diameter at the periapical area and interdental area of spongious bone were used. The analysis of image according to the variance of lesion size by 0.25, 0.35, 0.55, and 0.85mm serially was performed by the histogram and the color enhancement with subtraction. The images inputted by CCDcamera were digitized and analyzed by NEXUS QUBE program with NEC PC-9801 computer. The obtained results were as follows: 1. There was no reliability in the analysis of lesions by contour line 2 .. The mean difference of the grey scale at each pixel was 1 step between reference image and the corrected images. 3. In the analysis by histogram of the artificial lesion in spongeous bone, the change over 0.55mm in the mesiodistal size was detectable by the change of the numbers of pixel showing the change in grey scale. 4. In the analysis by histogram of the artificial lesion in spongeous bone, the change over 0.25mm in the buccolingual size was detectable by the change in grey scale. 5. By color enbancement with- subtraction, each lesion was able to be isolated and the change in it's mesiodistal size was detectable visually , but not in it's buccolingual size.

의료 서비스와 디자인

최원재,Choi, Won-Jae 대한소아치과학회 2016 大韓小兒齒科學會誌 Vol.43 No.4

의료와 관련하여 디자인은 대표적으로 시각디자인(Visual Communication Design), 제품디자인(Product Design) 그리고 환경디자인(Environment Design)이 의료 환경을 미적으로 아름답고 편리하도록 지원하는 형태로 관계를 형성하고 발달해왔다. 그러나 근래 디자인에 있어서 전문성이 증대되고, 다양한 영역과 학문과 융합하여 세분화되고 전문화된 영역이 새롭게 생성되고 있다. 더불어 디자인은 기술의 발달로 인하여 다양한 산업, 학문, 서비스와 융합하여 새로운 형태의 모델을 만들며 끝임 없이 변화하고 있는 상황이다. 이러한 디자인의 변화와 발달의 상황을 인식하고 의료 서비스에 있어서 디자인 활용에 대한 연구를 진행하여, 전통적인 디자인의 영역에 한정적으로 활용되던 디자인에서 벗어나 새로운 가치를 창출할 수 있는 의료 서비스 디자인으로 발전해 나가는 연구를 제안한다. In connection with medical care, designs have been developed by forming relationships, typically supporting Visual Communication Design, Product Design and Environment Design healthcare environment aesthetically pleasing and convenient. However, in recent designs, expertise has increased, new areas specialized are merged with various areas and academic disciplines and subdivided. In addition, due to the development of technology, the design has been continuously changing, creating a new form of model by fusing with various industries, academics and services. Recognizing the changes and developments of these designs, we are promoting research on utilization of design in medical services, we can create a new value by getting out of design that we have limitedly used in areas of traditional design I will try to know about developing into a design.

국내 내연기관차, 하이브리드차, 전기차, 연료전지차의 전과정 온실가스 배출량 비교

최원재(Won Jae Choi),유은지(Eunji Yoo),설은수(Eunsu Seol),김명수(Myungsoo Kim),송한호(Han Ho Song) 한국자동차공학회 2017 한국자동차공학회 부문종합 학술대회 Vol.2017 No.5

Unfamiliar visual experience

Won Jae Choi(최원재) 한국디자인학회 2023 한국디자인학회 국제초대전도록 Vol.2023 No.12

인회석 박막 피복 도관과 Brain-derived neurotrophic factor(BDNF) 유전자 이입 슈반세포를 이용한 백서 좌골신경 재생에 관한 연구

최원재(Won-Jae Choi),안강민(Kang-Min Ahn),황순정(Soon-Jeong Hwang),정필훈(Pill-Hoon Choung),김명진(Myung-Jin Kim),김남열(Nam-Yeol Kim),유상배(Sang-Bae Yoo),장정원(Jeong-Won Jahng),김현만(Hyun-Man Kim),김중수(Joong-Soo Kim),김윤희(Yun 대한구강악안면외과학회 2005 대한구강악안면외과학회지 Vol.31 No.3

Purpose of Study: Peripheral nerve regeneration depends on neurotrophism of distal nerve stump, recovery potential of neuron, supporting cell like Schwann cell and neurotrophic factors such as BDNF. Peripheral nerve regeneration can be enhanced by the conduit which connects the both sides of transected nerve. The conduit maintains the effects of neurotrophism and BDNF produced by Schwann cells which can be made by gene therapy. In this study, we tried to enhance the peripheral nerve regeneration by using calcium phosphate coated porous conduit and BDNF-Adenovirus infected Schwann cells in sciatic nerve of rats. Materials and Methods: Microporous filter which permits the tissue fluid essential for nerve regeneration and does not permit infiltration of fibroblasts, was made into 2mm diameter and 17mm length conduit. Then it was coated with calcium phosphate to improve the Schwann cell adhesion and survival. The coated filter was evaluated by SEM examination and MTT assay. For effective allogenic Schwann cell culture, dorsal root ganglia of 1-day old rat were extracted and treated with enzyme and antimitotic Ara-C. Human BDNF cDNA was obtained from cDNA library and amplified using PCR. BDNF gene was inserted into adenovirus shuttle vector pAACCMVpARS in which E1 was deleted. We infected the BDNF-Ad into 293 human mammary kidney cell-line and obtained the virus plaque 2 days later. RT-PCR was performed to evaluate the secretion of BDNF in infected Schwann cells. To determine the most optimal m.o.i of BDNF-Ad, we infected the Schwann cells with LacZ adenovirus in 1, 20, 50, 75, 100, 250 m.o.i for 2 hours and stained with 􀝜-galactosidase. Rats(n=24) weighing around 300g were used. Total 14mm sciatic nerve defect was made and connected with calcium phosphate coated conduits. Schwann cells(1x106) or BDNF-Ad infected Schwann cells(1x106) were injected in conduit and only media(MEM) was injected in control group. Twelve weeks after surgery, degree of nerve regeneration was evaluated with gait analysis, electrophysiologic measurements and histomorphometric analysis. Results: 1. Microporous Millipore filter was effective conduit which permitted the adhesion of Schwann cells and inhibited the adhesion of fibroblast. We could enhance the Schwann cell adhesion and survival by coating Millipore filter with calcium phosphate. 2. Schwann cell culture technique using repeated treatment of Ara-C and GDNF was established. The mean number of Schwann cells obtained 1 and 2 weeks after the culture were 1.54±4.0×106 and 9.66±9.6×106. 3. The mRNA of BDNF in BDNF-Ad infected Schwann cells was detected using RT-PCR. In Schwann cell 0.69 μg/μl of DNA was detected and in BDNF-Adenovirus transfected Schwann cell 0.795 μg/μl of DNA was detected. The most effective infection concentration was determined by LacZ Adenovirus and 75 m.o.i was found the most optimal. Conclusion: BDNF-Ad transfected Schwann cells successfully regenerated the 14mm nerve gap which was connected with calcium phosphate coated Millipore filter. The BDNF-Ad group showed better results compared with Schwann cells only group and control group in aspect to sciatic function index, electrophysiologic measurements and histomorphometric analysis.

헤드폰을 이용한 가상음향 재현의 주관적, 객관적 평가

최원재(Won-jae Choi),김상명(Sang-Myeong Kim) 한국소음진동공학회 2003 한국소음진동공학회 학술대회논문집 Vol.2003 No.5

마이크로사이트의 모션그래픽 활용에 관한 연구 : 국내 휴대전자제품 마이크로사이트를 중심으로

최원재 ( Won Jae Choi ) 한국기초조형학회 2006 기초조형학연구 Vol.7 No.3

역사 데이터 내러티브

최원재(Choi, Won-jae) 동국역사문화연구소 2020 동국사학 Vol.68 No.-

This study examined a new role of history (or history research) which was little focused in terms of data science before. We are living in the data era where data is a core in industry, business, and study, and no doubt, anyone should be data literate to live in this data-centred society. However, it does not mean everyone ought to become a computer scientist or computer programmer. History will be where data literacy is taught and experienced with its historical thinking that derives from interpreting big data and small data we can encounter in history or history research. A history researcher comes across the moment when ‘Aha!’ occurs to him or her in researching historical events or episodes from analyzing contexts and weaving them, and it is insight and intuition that is required to whoever deals with data. Historical research results in insight and intuition. History research is not where the past remained only in the past but where data is analyzed and interpreted with insight and intuition of a data researcher who dives into finding a new fact and pursuing after its novel interpretation. By doing so, anyone who is involved in historical research can be literate in data. Data literacy is not limited in the computer field as simply thought. From a broad scope, its bounds are getting expanded to where interpretational insight in data can be harvested, and digital data curation is recommended for a specific way to realize data literacy. Digital data curation calls for both computer skills and interpretational insight or intuition. It is the very best thing in getting the narrative shaped which a researcher explores in the way the data-oriented society welcomes. Digital data curation is hopefully expected to be placed in a curriculum of historical research. 이 연구의 목적은 데이터 시대에 역사학의 새로운 역할에 대해 고찰하는 데 있다. 데이터가 본격적으로 산업의 주재료가 된 지금은 누구나 데이터를 재료로 첨단기술을 활용해 일하고 더 나아가 새로운 비즈니스 모델을 만들어낼 수 있는 데이터 활용 역량을 키울 수 있어야 한다. 데이터 리터러시가 필요에서 ‘필수’인 시대로 접어들었다. 이러한 역량을 이끌 수 있는 학문으로 역사학을 꼽을 수 있다. 역사학은 그 시작점이 데이터가 바탕이 되는 데이터 과학이다. 그리고 역사학에서 요구하는 역사적 사고는 데이터 리터러시 역량과 다르지 않다. 역사 연구에서 펼쳐지는 역사적 사고는 데이터를 수집·정리하고 분석하는 것을 넘어 데이터를 해석할 수 있는 직관과 통찰을 기를 수 있는 토대를 마련해준다. 역사적 사고는 역사적사건과 사실을 분석하고 사건·사실의 상황 맥락을 파악하고 해석하는 사고(思考)를 포함하는데 이런 해석의 과정에서 직관력과 통찰력을 기를 수 있는 것이다. 역사는 데이터베이스의 학문이며 역사 연구는 데이터 해석의 과정이다. 다시 말해 역사는 데이터를 해석하여 활용할 수 있는 데이터 내러티브 능력이 발현될 수 있는 영역이다. 역사적 사고력을 데이터 리터러시로 완성시킬 수 있는 구체적으로 방법으로 디지털 데이터 큐레이션이 있다. 디지털 데이터 큐레이션은 구현하고자 하는 내용을 기획하여 이에 맞는 데이터를 디지털 기술로 데이터베이스화하고 여기서 다시 데이터를 추출·연결하여 디지털적으로 재구성하는 내러티브 기법이다. 디지털 데이터 큐레이션을 원활히 구현하기 위해서는 데이터를 엮어가는 사고력과 디지털 기술 응용력이 모두 요구된다. 역사학에서 배울 수 있는 역사적 사고가 디지털 기술과 융합되면 앞으로 데이터 활용에 요구되는 직관력과 컴퓨터 기술을 모두 습득하게 될 것이다. 역사학은 데이터 중심 시대에 더이상 지난 세월의 사료를 읽고 교훈을 얻는 과거에 머물러 있는 학문이 아니다. 디지털 데이터 큐레이션 속에서 구현되는 역사적 사고는 역사적 데이터를 확인하고 그 데이터 사이의 맥락(관계성)을 짚어가는 데 필수적인 직관력을 길러 내러티브할 수 있는 데이터 과학의 주요 분야로 역사학을 본격적인 데이터 과학의 하나로 규정할 수 있을 것이다. 본 연구자는 역사학 커리큘럼에 디지털 데이터 큐레이션을 포함할 것을 제안한다. 본 연구는 독립운동가 김동수 선생 가문 디지털 큐레이션에서 발견한 스토리를 연구 사례로 들어 디지털 데이터 내러티브인 역사 디지털 큐레이션의 구체적인 연구 과정을 설명한다.

국내 전기자동차의 전과정 온실가스 배출량 분석

최원재(Won Jae Choi),유은지(Eunji Yoo),설은수(Eunsu Seol),김명수(Myungsoo Kim),송한호(Han Ho Song) 한국자동차공학회 2016 한국자동차공학회 부문종합 학술대회 Vol.2016 No.5

C3H8, N2O, N2 냉매를 적용한 천연가스 액화사이클의 다단 압축 성능 특성

최원재(Won-Jae Choi),손창효(Chang-Hyo Son),윤정인(Jung-In Yoon),이상규(Sang-Gyu Lee),최건형(Keun-Hyung Choi),유선일(Sun-Il Yoo) 한국마린엔지니어링학회 2010 한국마린엔지니어링학회 학술대회 논문집 Vol.2010 No.10

This paper presents a new natural gas liquefaction cycle which utilizes propane (C3H8), nitrogen monoxide (N2O), and nitrogen gas(N2)cycles. A liquefaction cycle with staged compression was designed and simulated using HYSYS software for improving cycle efficiency. This included a cascade cycle with a three-stage compression consisting of a C3H8, a N2O and a N2 cycle. These cycles were compared with an optimized staged compression process. The Compressor work and specific energy of the cascade cycles were compared and analyzed. The new C3H8, N2O and N2 liquefaction cycle is also compared to other natural gas liquefaction cycles including the Phillips optimized cascade cycle. The new liquefaction cycle requires less power for the same liquefied natural gas (LNG) quantity produced by other methods. For example, up to 14.3% less power is consumed using the new method as opposed to the Phillips optimized cascade cycle under the same conditions of feed gas composition and liquefaction rate.