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증례 : 내분비-대사 ; 초기 절제술 16년 후 다발성 원격 전이된 악성 부신경절종 1예
문을선 ( Eul Sun Moon ),민혜숙 ( Hye Sook Min ),정창호 ( Chang Ho Jung ),최종현 ( Jong Hyun Choi ),김준석 ( Jun Suk Kim ),류혜진 ( Hye Jin Yoo ),최상룡 ( Sang Yong Choi ) 대한내과학회 2014 대한내과학회지 Vol.87 No.4
Paragangliomas are rare tumors that arise from the extra-adrenal chromaffin cells, and malignancy is defined by the presence of metastases to sites that normally lack chroma.n tissue. The main therapeutic targets are tumor reduction and control of excessive catecholamine secretion. Currently, the adjuvant therapy to surgery is radiotherapy treatment using high-dose MIBG; chemotherapy is currently evolving. We report herein a case of malignant paraganglioma with lung and spine metastasis that occurred 16 years after primary tumor excision and was treated with high dose MIBG radiotherapy and chemotherapy. (Korean J Med 2014;87:484-490)