대구시 하수처리장 운전실태에 따른 중수도 도입 방안 연구

최미영,나욱호,홍원화,김삼열,Choi Mi-Young,Na Wook-Ho,Hong Won-Hwa,Kim Sam-Yeul 한국주거학회 2005 한국주거학회 논문집 Vol.16 No.1

It has seen the significant increase of water consumption rate due to rapid industrialization, high-densities of city, and increasing the population; thereby leads further water resource required in near future. In order to solve this deficit there are one of solution that gray water method demonstrates advantages regarding the questions of optimal water utility and thereby master plan of water. The method of study is analysis of investigation data through interview and research of sewage treatment plants in Daegu City. Through these analysis, this paper examines the capacity of graywater and optimal graywater facility.

5-11세 소아에서 코로나19 백신의 효능 및 안전성에 대한 체계적 문헌고찰

최미영,유수연,정채림,최영준,최수한,Choi, Miyoung,Yu, Su-Yeon,Cheong, Chelim,Choe, Young June,Choi, Soo-Han 대한소아감염학회 2022 Pediatric Infection and Vaccine Vol.29 No.1

Purpose: To evaluate the efficacy and safety of coronavirus disease 2019 (COVID-19) vaccines in children aged 5-11 years, a rapid systematic review was conducted on published clinical trials of COVID-19 vaccines and studies that analyzed real-world data on adverse events after COVID-19 vaccination. Methods: A systematic search was conducted on medical literature in international (Ovid-MEDLINE) and pre-published literature databases (medRxiv), followed by handsearching up to January 4, 2022. We used terms including COVID-19, severe acute respiratory syndrome coronavirus 2, and vaccines, and the certainty of evidence was graded using the GRADE approach. Results: A total of 1,675 studies were identified, of which five were finally selected. Among the five studies, four consisted of data from clinical trials of each of the four types of COVID-19 vaccines (BNT162b2, mRNA-1273, CoronaVac, and BBIBP-CorV). The remaining study consisted of real-world data on the safety of the BNT162b2 vaccine in children aged 5-11 years. This systematic review identified that COVID-19 vaccines in recipients aged 5-11 years produced a favorable immune response, and were vaccines were effective against COVID-19. The safety findings for the BNT162b2 vaccine in children and early adolescents aged 5-11 years were similar to those data noted in the clinical trial. Conclusions: There is limited data on COVID-19 vaccines in children aged 5-11 years. Consequently continuous and comprehensive monitoring is necessary for the evaluation of the safety and effectiveness of the COVID-19 vaccines.

가미생간탕(加味生肝湯)이 고지방식이로 유발된 지방간에 미치는 영향

최미영,우홍정,김영철,이장훈,Choi, Mi-Young,Woo, Hong-Jung,Kim, Young-Chul,Lee, Jang-Hoon 대한한방내과학회 2009 大韓韓方內科學會誌 Vol.30 No.2

Objectives : The aim of this study was to investigate the effects of Gamisaenggan-tang on high fat diet induced nonalcoholic fatty liver disease. Methods: Rats were randomly divided into four groups. The Normal group was fed a solid diet containing 10% fat. The Gamisaenggan-tang (GS) group was fed a solid diet containing 10% fat and Gamisaenggan-tang (90mg/100g body weight). The Control group was fed a solid diet containing 60% fat. The HFD-Gamisaenggan-tang (HFD-GS) group was fed a solid diet containing 60% fat and Gamisaenggan-tang (90mg/100g body weight). Six weeks later, rats body weight, liver weight, serum ALT, GGT, ALP levels were measured. Histological findings (Oil red O staining), hepatic triglyceride, TNF-${\alpha}$, and TGF-${\beta}$ levels in the liver tissue were studied. Results: Average body weight of the HFD-GS group was significantly less than that of the Control group. There were no significant liver weight differences among each group. The GGT levels of the HFD-GS group were significantly less than those of the Control group. However, there were no significant differences in the ALT or ALP levels among the groups. TNF-${\alpha}$ protein production assessed by western blot analysis was reduced by Gamisaenggan-tang. Greater fat accumulation was observed in the liver tissue of the Control group than in the HFD-GS group, which means the Gamisaenggan-tang has an inhibitory effect on the accumulation of fat in the liver. Conclusion : The results suggest that Gamisaenggan-tang can be potential candidate for the treatment of nonalcoholic fatty liver disease in clinics.

N4SSB 단백질의 C-말단기의 7개의 아미노산이 N4SSB 단백질의 in vivo 활성에 미치는 영향

최미영,Choi, Mieyoung 한국미생물학회 1998 미생물학회지 Vol.34 No.4

Bacteriophage N4, a lytic phage specific for Esherichia coli K12 strain encodes single-stranded DNA-binding protein, N4SSB (bacteriophage N4-coded single-stranded DNA-binding protein). N4SSB protein is originally identified as a protein required for N4 DNA replication. N4SSB protein is also required for N4 late transcription, which is catalyzed by E. coli ${\sigma}^{70}$ RNA polymerase. N4 late transcription does not occur until N4SSB protein is synthesized. Recently it is reported that N4SSB protein is essential for N4 DNA recombination. Therefore N 4SSB protein is a multifunctional protein required for N4 DNA replication, late transcription, and N4 DNA recombination. In this study, a variety of mutant N4SSB proteins containing internal deletions or substitutions were constructed to define and characterize domains important for N4 DNA replication, late transcription, and N4 DNA recombination. Test for the ill vivo activity of these mutant N4SSBs for N4 DNA replication, late transcription, and N4 DNA recombination was examined. The results suggest that C-terminal 7 amino acid residues are important for the activity of N4SSB. Three lysine residues, which are contained in this region play important roles on N4SSB activity. Esherichia coli(E. coli) K12 균주를 숙주세포로 삼는 박테리오파아지인 N4는 single-stranded DNA에 결합하는 단백질인 N4SSB(bacteriophage N4-coded single-stranded DNA-binding protein) 단백질을 만든다. N4SSB 단백질은 N4 DNA replication 뿐만 아니라 late transcription과 N4 DNA recombination에도 필요한 여러 가지 기능을 가진 단백질이다. N4 late transcription은 숙주세포인 E. coli의 $E{\sigma}^{70}$ RNA polymerase에 의해서 수행이 되나 N4SSB 단백질을 반드시 필요로 하기 때문에 N4SSB 단백질이 생성될 때까지는 N4 late promoter로부터 RNA 합성이 일어나지 않는다. 본 연구에서는 N4SSB의 N4 DNA replication과 late transcription, 그리고 N4 DNA recombination에 필요한 영역(domain)을 알아내기 위해서 여러 가지 돌연변이형 N4SSB 단백질을 만들어 N4 DNA replication과 late transcription, 그리고 N4 DNA recombination의 3가지 작용에 대한 in vivo 활성을 조사 분석하였다. 그 결과 N4SSB 단백질의 C-말단기에 있는 7개의 아미노산이 N4SSB 단백질의 활성에 중요하다는 것을 알 수 있었다. 특히 C-말단기의 7개의 아미노산에는 세 개의 lysine이 포함되어 있는데 이 lysine이 N4SSB 단백질의 활성에 중요한 역할을 한다는 것이 제시되었다.

한 눈의 시력이 0.1 이하인 순수 굴절부등약시의 임상 분석

최미영,김연희,Mi Young Choi,Youn Hui Kim 대한안과학회 2008 대한안과학회지 Vol.49 No.6

Purpose: To analyze the results of treatment in pure anisometrpic amblyopia with unilateral visual acuity of 0.1 or worse. Methods: The major eligibility criteria included pure anisometropic amblyopia with age <10 years, best-corrected visual acuity 0.1 or worse in the worse eye and 0.5 or better in the good eye after the wearing of optimal spectacle correction for a minimum of 4 weeks, and the minimum follow-up was 6 months. Twenty-one patients were selected and we analyzed the age at the amblyopia treatment, the type and degree of anisometropia, and the final visual acuity after treatment for visual improvement. Successful treatment was defined as a final visual acuity of 0.3 or more. Results: The mean age at treatment was 5.2 years. The types of anisometropia were hypermetropic in 14 patients, astigmatic in 4, and myopic in 3. The mean duration of treatment of amblyopia was 16 months, and 13 of 21 children with pure anisometropic amblyopia achieved 0.3 or better. The age at treatment was younger and the compliance rate was higher in the success group than in the failure group. Conclusions: The most common type was hyperopic in the pure anisomteropic amblyopia. Compliance and age at treatment were significantly related to best visual acuity attained in pure anisometropic amblyopia with unilateral visual acuity of 0.1 or worse. J Korean Ophthalmol Soc 49(6):973-978, 2008

기질약시에 의한 소아 감각사시의 임상 분석

최미영,황정민,Mi-Young Choi,Jeong-Min Hwang 대한안과학회 2005 대한안과학회지 Vol.46 No.8

Purpose: To study the clinical characteristics of pediatric sensory strabismus in Korean children. Methods: A retrospective analysis was performed on 71 patients with the diagnosis of sensory strabismus before the age of 16 years. Patients with strabismic amblyopia or anisometropic amblyopia were excluded from consideration. The age at onset of vision loss, diagnosis, type of strabismus, deviated angle, etiologic factors leading to vision loss, and visual acuity of the deviated eye were recorded. The surgical results were analyzed in the case of strabismus surgery for sensory strabismus. Results: The mean age at the onset of vision loss was 4.6 years and the mean age at diagnosis was 7.5 years. Forty-one patients (58%) had congenital vision loss and the most common cause of vision loss was optic nerve disease in 35 (49%). Exotropia developed in 58 (82%), and patients with severely impaired visual acuity were more likely to develop exotropia (P=0.054). The age at the onset of vision loss and the age at diagnosis in esotropia were younger than in exotropia (P=0.049, P=0.047, respectively). Twenty-five (78%) of 32 patients who had undergonewere strabismus surgery had ocular alignment within 10 prism diopters of orthophoria. The frequency of consecutive exotropia was 40% in surgery for esotropia. Conclusions: Children with organic amblyopia tend to develop sensory exotropia. We considered that the age at initial vision loss and the severity of vision loss could play a role in determining the direction of deviation. The surgical results were favorable, but we should pay attention to the development of consecutive exotropia in surgery for esotropia.

소아 눈모음부족외사시에서 근거리/원거리 사시각에 따른 단안 절제술 및 후전술

최미영,황정민.Mi-Young Choi. M.D.. Jeong-Min Hwang. M.D. 대한안과학회 2005 대한안과학회지 Vol.46 No.10

Purpose: The purpose of this study was to evaluate prospectively the long-term surgical results of unilateral lateral rectus (LR) muscle recession and medial rectus (MR) muscle resection in children with convergence insufficiency exotropia (XT). Methods: This prospective study included 14 children with an angle of XT greater at near than at distance by 10 prism diopters (PD) or more. The amounts of resection and recession were based on near and distance deviation, respectively. Minimum follow-up was one year (mean, 26.6±19.4 months) after surgery. Results: Significant postoperative reduction was achieved in mean distance exodeviation from 22.5 PD to 9.1 PD (p=0.000), and in mean near exodeviation from 33.8 PD to 13.6 PD (p=0.000). The mean near-distance difference decreased from 11.3 PD preoperatively to 4.6 PD postoperatively (p=0.000). A Fresnel prism was used temporarily to treat postoperative esotropia in only one patient for 6 months postoperatively. Conclusions: Unilateral surgery biased more to MR strengthening than to LR weakening in children with convergence insufficiency XT, was found to successfully reduce both distance and near deviation and to collapse near-distance differences with a low risk of long-term postoperative esotropia.

특집 : 패션 마케팅 현황과 전략 ; 소비자 선호컬러 활용과 컬러 트렌드 기획

최미영 ( Mi Young Choi ),심영완 ( Young Wan Shim ) 한국의류학회 2005 패션정보와 기술 Vol.2 No.-

사회과학분야 : 엘리트 댄스스포츠 지도자와 선수의 상호작용 형성 과정

최미영 ( Mi Young Choi ) 한국무용과학회 2015 한국무용과학회지 Vol.32 No.1

본 연구는 엘리트 댄스스포츠 지도자와 선수가 경기력 향상과 개인의 성장을 위해 처음 만남부터 현재까지 어떠한 상호작용 과정을 거치는지를 파악하고자 질적 연구방법인 문화기술적 사례연구를 적용하였다. 연구 참여자는 이상적 사례 선택(ideal case selection)을 사용하여 국가대표 지도자와 선수 한 팀을 선정하였다. 자료 수집은 2013년 11월 23일부터 2014년 4월 5일까지 5개월간(총 6회)에 걸친 심층면담과 참여관찰 3회를 실시하였다. 수집된 자료는 다각도 분석 (triangulation)을 통해 다음과 같은 연구결과를 얻었다. 첫 번째, 엘리트 댄스스포츠 지도자와 선수가 협력하는 상호작 용 요소는 지속적인 동기부여, 헌신적인지지, 적극적인 갈등관리, 긍정적인 대처, 자기통제가 분류되었다. 두 번째, 엘리 트 댄스스포츠 지도자와 선수의 상호작용 과정은 형성기(수직적관계), 성장기(중첩된관계), 침체기(과도지적관계), 제2의 형성기(수평적관계)가 파악되었다. 이러한 연구결과는 엘리트 댄스스포츠 지도자와 선수의 경기력 향상과 개인의 성장 에 긍정적으로 영향을 미치는 상호작용과 상호관계에 관련된 교육적이고 기술적인 자료를 제시할 것이다 The purpose of this study is to investigate the relationship formation process between elite dance sports leaders and players beginning with their first meeting to current relationship in their efforts to enhance performance and individual player``s growth. In order to verify interactive factor between them, an ethnography case study was employed among qualitative research methods by selecting dance sports leaders and players of the national team. We collected data from November 23, 2013 to April 5, 2014 through in-depth interview(6 times) and participatory observation(3 times). As the result, interactive factors getting motivation continuously, support, conflict management, positive attitude, self control As the second purpose of this study, The results showed that four consistent patterns of developmental phases were found from the participants such as the phase of formation, development, depression, and the second formation. The implications of this study provide pedagogical and descriptive data associated with interaction and relationship that positively make an impact on elite dance sports leaders`` and players`` performance enhancement and individual growth.

지적장애 학생의 기초 탐구 기능 평가

최미영 ( Mi Young Choi ) 한국특수교육문제연구소 2014 특수교육저널 : 이론과 실천 Vol.15 No.4

수도권에 위치한 3개 특수학교의 지적장애 중·고등학생 8명(남 4명, 여 4명)을 대상으로 탐구 활동을 통한 기초 탐구 기능(관찰, 분류, 측정, 예상, 추리)을 평가하였다. 선행 연구의 분석틀을 기준으로 기초 탐구 기능 요소별 특성을 질적으로 분석하였고, IQ에 따른 차이가 있는지를 알아보았다. 그 결과는 다음과 같다. 첫째, 대부분의 지적장애 학생들은 주로 일부 감각만을 사용한 단순 관찰과 경험이나 추측에 근거한 비과학적 관찰을 하였다. 둘째, 대부분 물체의 속성을 잘 파악하지 못하거나 분류기준 및 방법에 대해 잘 알지 못하였다. 셋째, 대부분 과학 실험 기구의 조작이 서툴러 비과학적으로 측정하였다. 넷째, 대부분 인과관계와 경향성을 잘 파악하지 못하여 바르게 예상하지 못하였다. 다섯째, 일부를 제외한 대부분의 학생들이 객관적이고 사실적인 정보를 바탕으로 바르게 추리하였다. 마지막으로 측정의 일부 기능과 추리 기능을 제외한 나머지 기초 탐구 기능 요소에서 IQ에 따른 차이가 나타났다. 이러한 결과를 바탕으로, 장애학생의 기초 탐구 기능 향상에 대해 논의하였다. This study was to assess the basic science process skills through science inquiry activities for 8 students with intellectual disability in special schools. The results were as follows. First, most students mainly performed simple observation in a certain sense or observation based on guess or experience from real life. Second, most students did not know the method and the criterion to classify or identify properties of objects correctly. Third, most students were unable to measure scientifically because of poor skills to manipulate for science experiment equipments. Fourth, most students did not identify the relationship between cause and effect and tendency, so that they could not predict it well. Fifth, some students had a good reasoning based on objective and realistic informations. Sixth, there were some differences in the basic process skills according to IQ except some measurement and reasoning. Lastly it was discussed the enhancement of the basic process skills for students with disabilities.