근시성 굴절이상이 Topog raphic Scanning System을 이용한 시신경 유두부 분석에 미치는 영향

최규룡(Kyu Ryong Choi),홍해진(Hae Jin Hong) 대한안과학회 2000 대한안과학회지 Vol.41 No.6

고혈압성 흰쥐에서 nifedipine 투여가 혈압과 수정체의 수분함량 및 양이온 평형에 미치는 영향

최규룡(Kyu Ryong Choi),전애경(Ae Kyung Jun),조병채(Byung Chae Cho),박미애(Mi Ae Park) 대한안과학회 1989 대한안과학회지 Vol.30 No.4

Nerve Fiber Analyzer 에 의한 망막 시신경 두께 측정의 재현성

최규룡(Kyu Ryong Choi) 대한안과학회 1997 대한안과학회지 Vol.38 No.6

녹내장 의증 환자의 감별에서 가변각막보정 주사레이저편광측정의 진단적 가치

김현진,최규룡,Hyun-Jin Kim,Kyu-Ryong Choi 대한안과학회 2007 대한안과학회지 Vol.48 No.12

Purpose: This study was designed to assess the diagnostic value of scanning laser polarimetry with variable corneal compensation (GDx-VCC) in the diagnosis of preperimetric glaucoma. Methods: The study included 132 eyes of 132 patients with normal intraocular pressure, including 38 normal eyes, 60 eyes with pre-perimetric glaucoma, and 34 eyes with early glaucoma. The parameters of GDx-VCC were analyzed and compared in these groups using ANOVA. The parameter with the most powerful diagnostic value was defermirred by an ROC curve, and it`s sensitivity and specificity were calculated. Results: Among GDx-VCC parameters, NFI was the most valuable parameter that could detect pre-perimetric glaucoma in normal eyes. A cut-off value of 12 was the optimal NFI value, which offered the highest sensitivity and specificity in discriminating between normal and pre-perimetric glaucomatous eyes. However, there were no statistically significant differences in GDx-VCC parameters between pre-perimetric and early glaucomatous eyes. A statistically significant correlation was found between NFI and visual field indices in early glaucomatous eyes. Conclusions: GDx-VCC can be useful as a screening test for early detection of pre-perimetric and early glaucoma with normal intraocular pressure.

안축장이 짧은 안에서 인공수정체도수 산출 공식과 전방 깊이에 따른 정확성 분석

이영은,최규룡,전루민,Young-Eun Lee,Kyu-Ryong Choi,Roo Min Jun 대한안과학회 2010 대한안과학회지 Vol.51 No.10

Purpose: To evaluate the accuracy of intraocular lens (IOL) power calculations according to the chosen formulas and anterior chamber depths in eyes with short axial lengths. Methods: A retrospective analysis was performed on 57 eyes of 50 patients (axial length < 22.0 mm) and 42 eyes of 36 patients (22.0 mm ≤ axial length < 25.0 mm) who underwent cataract surgery. IOL power was calculated with the SRK II, SRK/T, Binkhorst, Holladay I, and Hoffer Q formulas. The differences between the predicted refraction and the actual refraction were compared and analyzed. The errors according to the anterior chamber depth were also evaluated. Results: The SRK II formula showed a lower predictive accuracy, and the other formulas showed similar accuracies in eyes with short axial lengths. The Holladay 1 and Hoffer Q formulas showed good predictive accuracies in eyes with short axial lengths. Hyperopic shift tended to occur with all formulas in eyes with short axial lengths. When using SRK II and SRK/T formulas, a correlation between axial length and hyperopic shift was observed, with shorter axial length patients shifting to more hyperopic conditions. In eyes with short axial lengths, larger hyperopic shifts tended to occur in eyes with relatively deeper anterior chambers. Conclusions: In eyes with short axial lengths, preoperative predicted IOL power showed good accuracies with Holladay 1 and Hoffer Q formulas. Preoperative anterior chamber depth and axial length had a strong influence on the accuracies of predicted IOL power. J Korean Ophthalmol Soc 2010;51(10):1338-1344

유리체강내 트리암시놀론 주사 후 안압 상승에 대한 임상양상 분석

오민진,최규룡,이수영,이정희,Min Jin Oh,Kyu Ryong Choi,Soo Young Lee,Jeong Hee Lee 대한안과학회 2006 대한안과학회지 Vol.47 No.10

Purpose: To evaluate the incidence of intraocular pressure (IOP) elevation and the associated factors following intravitreal triamcinolone acetonide injection. Methods: A retrospective observational case study was performed in 143 eyes of 143 patients who received intravitreal injection of 4 mg triamcinlone acetonide and who had a minimum follow-up of 6 months. The eyes were examined before and periodically after the intravitreal injection of triamcinolone acetonide. A significant IOP elevation was defined as IOP>21 mmHg or a rise of more than 5 mmHg in patient with IOP over 21 mmHg at their first examination. Results: Mean IOP increased from 16.1±3.2 mmHg preoperatively to 23.3±7.7 mmHg postoperatively. A significant IOP elevation was observed in 68 eyes (47.6%). IOP elevation was observed the day after injection and decreased to the baseline value after 6 months following injection. The time to reach maximum IOP was 3 months in 24.5%, 2 months in 20.3% and 1 week in 12.6%. Factors associated with IOP elevation were younger age, high IOP before injection, myopia, and unaccompanying anterior chamber paracentesis. Most cases of IOP elevation following intravitreal triamcinolone acetonide injection were controlled by antiglaucoma medication. However, in 4 eyes, filtering surgery or valve implantation was required. Conclusions: IOP elevation after intravitreal triamcinolone injection is common and may take an extended period of time to manifest. Cautious monitoring of IOP is recommended after intravitreal triamcinolone injection especially in younger patients and those with high IOP before injection, myopia, and unaccompanying anterior chamber paracentesis.

젊은 연령에서 정상안압녹내장 환자의 각막생체역학인자

류진영,최규룡,Jin Young Rhew,Kyu Ryong Choi 대한안과학회 2013 대한안과학회지 Vol.54 No.2

Purpose: To evaluate the corneal biomechanical properties and clinical characteristic of normal tension glaucoma (NTG) in young patients. Methods: We compared corneal biomechanical properties using an Ocular response analyzer (ORA) of under age 40 of 37 eyes of patients with NTG and 42 eyes of normal group. Results: The mean corneal resistance factor (CRF) and mean corneal hysteresis (CH) were significantly lower in NTG eyes (CRF, 9.2 ± 2.1 mm Hg; CH, 9.8 ± 1.8 mm Hg) than in normal eyes (CRF, 10.7 ± 2.3 mm Hg; CH, 10.9 ± 2.0 mm Hg; p = 0.01, p < 0.01). CH and CRF were associated with central corneal thickness (CCT) (CH; β = 0.354, p < 0.01, CRF; β = 0.348, p < 0.01) and glaucoma status (p < 0.01, p < 0.01). Conclusions: The CRF and CH were significantly lower in NTG group while IOP cc was not significantly different between the group. In diagnosing the NTG in young patients, ORA maybe useful for distinguishing between the glaucoma eyes and normal eyes.

정상안압녹내장의 시야손상 진행과 각막생체역학인자의 관련성

박종혁,최규룡.Jong Hyuk Park. MD. Kyu-Ryong Choi. MD 대한안과학회 2013 대한안과학회지 Vol.54 No.11

Purpose: To evaluate the association between corneal biomechanical properties and progression of visual field loss in normal tension glaucoma. Methods: This study enrolled 73 eyes of 73 patients with normal tension glaucoma who were undergoing medical treatment, and classified them into progressing and nonprogressing groups by visual field trend analysis. The corneal biomechanical properties measured by the Ocular Response Analyzer (ORA; Reichert Instruments, Depew, NY, USA), central corneal thickness, and Goldmann applanation tonometry were comparatively analyzed between the 2 groups. Results: Twenty-six eyes reached a progression endpoint. The prevalence of hypertension was higher in the progressing group (42.3%, progressing, 17.0%, nonprogressing; p = 0.03). Progressing eyes had lower corneal hysteresis (9.1 ± 1.3 vs. 9.8 ± 1.5 mm Hg, p = 0.03) and lower corneal resistance factor (9.5 ± 1.5 vs. 10.4 ± 1.4 mm Hg, p = 0.01) compared with nonprogressing eyes. Upon multivariate analysis, the presence of hypertension (odds ratio [OR] = 3.46, p = 0.03) and corneal hysteresis (CH) (OR = 0.66 per mm Hg lower, p = 0.02) remained statistically significant. Conclusions: The CH measurement with ORA was significantly associated with risk of visual field progression in normal tension glaucoma. Eyes with lower CH had a greater risk of progression of visual field loss than those with higher CH. J Korean Ophthalmol Soc 2013;54(11):1757-1766

난치성 녹내장에서 아메드 녹내장밸브 삽입술의 임상적 고찰

이현주,최규룡,Hyun Joo Lee,Kyu Ryong Choi 대한안과학회 2006 대한안과학회지 Vol.47 No.6

Purpose: To assess the efficacy, safety, and clinical outcome of the Ahmed glaucoma valve implant in refractory glaucoma. Methods: We retrospectively studied 55 eyes of 55 patients who underwent Ahmed glaucoma valve implantation for refractory glaucoma unresponsive to conventional management. The mean follow-up period was 26.3±11.5 months. Surgical success was defined as an intraocular pressure between 5 and 21 mmHg regardless of glaucoma medication. Results: The reduction of intraocular pressure was statistically significant (p<0.05) and the number of glaucoma medications was decreased. The 1-year and 2-year success rates were 83.0% and 75.8%, respectively. Complications included hyphema in 9 eyes, hypotony with shallow anterior chamber in 2 eyes, choroidal detachment in 4 eyes, tube obstruction in 1 eye, tube migration in 2 eyes, and bullous keratopathy in 2 eyes. Conclusions: Ahmed glaucoma valve implantation may provide good intraocular pressure control in patients with refractory glaucoma unresponsive to conventional treatments, and may be effective for reducing the incidence of hypotony in the early postoperative period.

50세 미만과 50세 이후에서 발생하는 안부 대상포진의 비교

조가은,최규룡,전루민,Ga Eun Cho,Kyu Ryong Choi,Roo Min Jun 대한안과학회 2013 대한안과학회지 Vol.54 No.1

Purpose: To study the clinical course of herpes zoster ophthalmicus (HZO) and to compare the demographics, treatments, and outcomes in patients under 50 years of age versus patients 50 years of age or older at the time of diagnosis. Methods: A retrospective chart review was performed of 102 patients who were diagnosed with HZO between January 1, 2008 and December 31, 2010. Baseline demographics and clinical characteristics between patients with an onset of HZO under the age of 50 years and patients with an onset of HZO at the age of 50 years or older were compared. Results: Similar numbers of patients were affected with HZO in the younger and older age groups (n = 44, 43.1%, vs. n = 58, 56.9%). The mean ± SD of age was 50.6 ± 21.8 years (range, 3-89 years) and the most common decade of HZO onset was between 50 and 59 years. Gender and disease laterality were not statistically different between the 2 groups. No significant difference was found regarding the presence of any ocular manifestation between the groups; however, anterior uveitis was more frequent in the younger patients (p = 0.04). The number of patients with immunosuppressive therapy was higher in the younger age group (p = 0.01). Conclusions: HZO-affected patients under the age of 50 years and older than 50 years were equally distributed, with the most common decade of onset between the age of 50 and 59 years. Younger patients had a higher incidence of anterior uveitis and immunosuppressive therapy due to underlying systemic diseases.