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배영덕 ( Young Deok Bae ),김수진 ( Soo Jin Kim ),남택만 ( Teck Man Nam ),조한수 ( Han Su Cho ),노승혁 ( Seung Hyuk Rho ),윤덕형 ( Duck Hyoung Yoon ),윤종우 ( Jong Woo Yoon ),이삼열,남은숙,오국환 ( Kook Hwan Oh ),채동완 ( Dong Wan Cha 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.6
Immunosuppressive medications after renal allograft transplantation have impacted the course of acute and chronic rejection; however, they have no defined effects on the prevention of recurrent and Glomerulonephritis (GN) in an allograft kidney. Authors experienced a case of rapidly progressive glomerulonephritis (RPGN). The 35-year-old female patient developed a rapid deterioration of renal function 4 years after renal transplantation. The allograft biopsy showed crescentic glomerulonephritis evolving from membranoproliferative glomerulonephritis (MPGN) type Ⅰ. She was given pulse steroid and oral cyclophosphamide therapy immediately after the renal biopsy. Graft function stabilized and proteinuria decreased even though graft function did not recover to pre-treatment level and low grade proteinuria persisted.