신호소실과 단계적 갑상선절제술

지용배(Yong Bae Ji) 대한신경모니터링학회 2022 Journal of Neuromonitoring & Neurophysiology Vol.2 No.2

Intraoperative nerve monitoring (IONM) provides dynamic neural information and is recommended for high-risk thyroid surgery. If RLN is severely injured during the operation, most nerve fibers do not transmit nerve impulse and substantial decrease of EMG amplitude or loss of signal (LOS) will occur. However, surgeon should differentiate the true LOS from false LOS, because it can be false due to various reason. If LOS is true, the decision to perform contralateral surgery to prevent bilateral vocal cord paralysis should be prudent. The updated causes, algorithm, and management of LOS during IONM and potential benefit of staged thyroidectomy are reviewed and summarized.

흉선에서 발생한 이소성 부갑상선 선종 1예

지용배(Yong Bae Ji),유병준(Byung Joon Yoo) 대한신경모니터링학회 2023 Journal of Neuromonitoring & Neurophysiology Vol.3 No.2

Primary hyperparathyroidism (PHPT) is a common endocrine disorder with elevated serum parathyroid hormone levels. In most cases, the disease involves a single parathyroid adenoma, followed by parathyroid hyperplasia. Parathyroid glands are rare, but can be present in a variety of locations because it migrates long distance during fetal period. Therefore, the incidence of ectopic parathyroid adenoma is rare and it is not easy to diagnose ectopic parathyroid adenomas and to specify the location before surgery. Recently, we diagnosed ectopic parathyroid adenoma at the thymus and treated successfully. So, we report this case with literature review.

갑상선 수술 중 신경 손상을 피하기 위한 수술 중 신경 모니터링의 활용

지용배(Yong Bae Ji) 대한신경모니터링학회 2021 Journal of Neuromonitoring & Neurophysiology Vol.1 No.1

Traditionally, visual identification of the nerve is the gold standard to avoid injury. Intraoperative neural monitoring (IONM) has been world-widely popularized in thyroid and parathyroid surgery because it helps identify the nerve. Despite the increasing use of IONM, there is a controversy that IONM can reduce recurrent laryngeal nerve (RLN) injury. It may be derived from the lack of uniformity in the application of and results from nerve monitoring between surgeons. IONM can not only be used to check the nerves, but it can also provide a lot of information to the surgeon. By using this information properly, the function of nerves can be monitored sensitively during surgery, and through this, a surgeon can be relatively freed from nerve damage. Proper use of IONM can improve the quality of neural monitoring and drive surgeons to best practices. In this paper, consistent and useful use of IONM has been described.

측경부 종괴로 표현된 기관지원성 낭종 1례

성의숙,지용배,김경래,박찬금,태경,Sung, Eui Suk,Ji, Yong Bae,Kim, Kyung Rae,Park, Chan Kum,Tae, Kyung 대한기관식도과학회 2011 大韓氣管食道科學會誌 Vol.17 No.2

A bronchogenic cyst is an uncommon benign congenital anomaly of the primitive ventral forgut which was generally encountered within the mediastinum and detected in pediatric patients. It is rarely detected in adult population as a lateral neck mass. We have recently experienced one case of bronchogenic cyst as a left lateral neck mass in a 49-year-old male. He complaints of a $2{\times}1$ cm sized, soft, non tender, and movable mass on the low lateral neck. The surgical excision of mass was performed and the final histopathologic diagnosis was a bronchogenic cyst. Here, we report this case with the review of literatures.

소타액선 종양의 고찰

태경(Kyung Tae),지용배(Yong Bae Ji),진봉준(Bong Jun Jin),이승환(Seung Hwan Lee),이형석(Hyung Seok Lee) 대한두경부종양학회 2005 대한두경부 종양학회지 Vol.21 No.2

Background and Objectives: Minor salivary gland tumors vary in their primary sites, histopathology and biological behavior. Therefore, various factors are considered in selecting the treatment modality and predicting the prognosis. We performed this study for the purpose of getting further understanding and more supporting ideas for the diagnosis and treatment of minor salivary gland tumor. Materials and Methods: A retrospective analysis of the patients with 52 cases of minor salivary gland tumor who were treated at the Hanyang University Hospital from 1996 to 2003 was performed. We analyzed demography, symptoms, histopathology, treatment and outcomes by the review of medical records. Results: Among 52 cases of minor salivary gland tumor, 46% were classified as benign and 54% were classified as malignant tumors. The most common benign tumor was pleomorphic adenoma. Adenoid cystic carcinoma(15/28) was the most common in malignant tumors. Eight patients were males and sixteen patients were females in benign tumors and 10 patients were males and 18 patients were females in malignant tumors. The most common site of benign tumor was the palate(17/22), whereas malignant tumors were most common in the nasal cavity and paranasal sinus(9/28). Asymptomatic mass was the most common symptom. According to the criteria given by the AJCC on staging, stage III and IV(21/28) were more common than stage I and 11(7/28). All benign tumors were treated with simple excision and had no recurrence. In malignant tumors, 25 patients underwent radical excisional operation and 13 patients of them had postoperative radiation therapy. Three of them were treated with additional chemotherapy. In whom treated with radical operation, 9 patients had recurrence. Three were recurred at the primary site with neck node metastasis, 3 were recurred at the primary site with lung metastasis, 1 was recurred at the primary site with neck node and lung metastasis, 1 was recurred only at neck node. Conclusion: In minor salivary gland tumor, malignant was more common than benign. Malignant tumor originated from minor salivary gland were more frequently diagnosed at advanced stage with high recurrence rate and distant metastasis. Early detection of the disease is needed to improve the prognosis of the patients with malignant tumors of the minor salivary glands.

갑상선 기능 저하증과 동반된 갑상선 반쪽 무형성증 1예

이동원(Dong Won Lee),지용배(Yong Bae Ji),송창면(Chang Myeon Song),태경(Kyung Tae) 대한두경부종양학회 2013 대한두경부 종양학회지 Vol.29 No.1

Thyroid hemiagenesis is rare congenital anomaly that one lobe of thyroid fails to develop. It is often asymptomatic and discovered incidentally with other thyroid disease such as hypothyroidism, hyperthyroidism, multinodular goiter, benign adenoma and cancer. Most cases reported are left thyroid lobe agenesis and occurred in female. Compensatory hypertrophy occurs in most cases. Many cases are asymptomatic and detected incidentally, so awareness of its existence can help its detection and proper treatment. Here, we report a case of thyroid hemiagenesis accompanying hypothyroidism with a review of literature.

라인케 부종에서 후두미세수술 후의 음성 결과

김민송,송창면,김건호,정선민,지용배,태경,Kim, Min Song,Song, Chang Myeon,Kim, Keon Ho,Jung, Seon Min,Ji, Yong Bae,Tae, Kyung 대한후두음성언어의학회 2017 대한후두음성언어의학회지 Vol.28 No.2

Background and Objectives : The management of Reinke's edema includes usually medical treatment and voice therapy. Laryngomicrosurgery (LMS) is also necessary, especially to improve airway obstruction. However, voice outcome after LMS has not been determined well. The aim of this study was to evaluate effectiveness of LMS for Reinke's edema and analyze the voice outcomes after LMS. Materials and Methods : Twenty-five patients with Reinke's edema who underwent LMS from September 2007 to December 2016 were enrolled in this study. We analyzed reflux finding score (RFS), reflux symptom index (RSI), and acoustic parameters before and after surgery. Results : Male was 15 (60%) and female was 10 (40%), and mean age was 49.6 years. Preoperative mean value of RFS decreased significantly up to 3 months after LMS ($18.3{\pm}2.2$ and $10.0{\pm}2.2$ at preoperative and 3 months postoperatively, respectively). The mean value of Jitter decreased significantly before and after surgery ($2.71{\pm}2.81%$ and $1.06{\pm}1.21%$ before and after LMS, p=0.041). The mean value of Shimmer also decreased significantly before and after surgery ($7.97{\pm}3.63%$ and $4.83{\pm}1.85%$, respectively, p=0.006). Conclusion : LMS is effective in the treatment of Reinke's edema. It results in favorable acoustic outcomes and laryngoscopic findings in properly selected patients.

접촉성 육아종에서 양성자 펌프 억제제의 치료 효과

김동환,김건호,정선민,송창면,지용배,태경,Kim, Dong Hwan,Kim, Keon Ho,Jung, Seon Min,Song, Chang Myeon,Ji, Yong Bae,Tae, Kyung 대한후두음성언어의학회 2017 대한후두음성언어의학회지 Vol.28 No.2

Background and Objectives : Contact granuloma is granulation tissue that occurs mainly in the vocal process of arytenoid cartilage. Among several etiological factors, gastric acid reflux is known to be an important cause. The aim of this study was to evaluate clinical characteristics of contact granuloma and analyze the effectiveness of proton pump inhibitor in the treatment of contact granuloma. Materials and Methods : We retrospectively reviewed the medical records of 40 patients who were treated with proton pump inhibitor (PPI) for contact granuloma from January 2011 to December 2015. Reflux finding score (RFS), reflux symptom index (RSI) and size of granuloma were evaluated before and after treatment serially to assess the effectiveness of proton pump inhibitor. Results : Of 40 patients, 25 patients (62.5%) and 10 patients (25%) showed improvement and partial improvement of granuloma, respectively. Five patients showed no response. The mean times of partial improvement and improvement were $2.08{\pm}2.23$ months and $4.60{\pm}2.77$ months, respectively and mean duration of PPI treatment was $6.8{\pm}5.2$ months. Conclusion : Proton pump inhibitors is effective in the treatment of contact granuloma.

경부에 발생한 지방육종 1예

태경(Kyung Tae),김경래(Kyung Rae Kim),지용배(Yong Bae Ji),박창호(Chang Ho Park) 대한두경부종양학회 2012 대한두경부 종양학회지 Vol.28 No.2

Liposarcoma is the second most common soft tissue sarcoma in adult. The incidence of liposarcoma in the head and neck area is very uncommon. Liposarcoma of the neck usually express non-tender palpable mass. The main treatment of cervical liposarcoma is surgical excision and adjuvant radiation therapy. Herein, we report a case of cervical liposarcoma with the review of literature.

상악동에 발생한 대세포 신경내분비 암종 1례

이윤재(Yun Jae Lee),정진혁(Jin Hyeok Jeong,),오영하(Young Ha Oh),지용배(Yong Bae Ji) 대한두경부종양학회 2019 대한두경부 종양학회지 Vol.35 No.2

Large cell neuroendocrine carcinoma is a rare epithelial neuroendocrine malignancy and is preferentially located in gastrointestinal tract and pancreas. Cases of large cell neuroendocrine carcinoma have been reported in many other locations, including the thymus, gallbladder, prostate, larynx, salivary glands, nasopharynx, tonsil and mastoid. However, primary sinonasal large cell neuroendocrine carcinoma never have been reported in Korea. We experienced a case of primary large cell neuroendocrine carcinoma arising from left maxillary sinus recently. A 82-year-old male patient presented with nasal obstruction and epistaxis. The biopsy revealed large cell neuroendocrine carcinoma with poor differentiation. After a general evaluation, the patient was staged as cT3N0M0. The patient was treated by combined radiotherapy and chemotherapy. We report this rare case with literature review.