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金在勉,林慶浩,趙惠濟 인제대학교 1983 仁濟醫學 Vol.4 No.1
先天的 直接型 Bilriubin血症의 한 형태인 Dubin-Johnson 症候群을 經驗하였기에 이를 報告하는 바이다. Dubin-Johnson Syndrome is one form of inherited direct bilirubinemia which is characterized by the second rise in BSP retntion test and the pigments grouped at centrilobular area in the liver biopy specimen. Authers experienced 1 case of Dubin-Johnson Syndrome. The patient of Dubin-Johnson Syndrome was a 24-year-old female, whore main complaints were intermittent RUQ abdominal pain and icteric sclera. By the use of BSP retention test and liver needle biopsy, we confirmed the diagnosis of Dubin-Johnson Syndrome. On the paitient, authors performed the study of the calorie restriction test and the Phenobarbital administration test for the purpose of ruling out the congenital indirect bilirubinemia, such as Gilbert's Disease. Both tests revealed that they are not reliable tests to differentiate Dubin-Johnson Syndrome from Gilbert's Disease. Also it showed the fact that calorie restriction can play a role of a stress to initiate bilirubinemia in Dubin-Johnson Syndrome. Oral GB study of the patient showed clear visualization of the GB, which suggests the possibility of racial characteristic of Dubin-Johnson Syndrome in Korean.