서울 지역 장염환아에서 분리되는 아데노바이러스 형별

조은경,이규만,정용훈,조양자,김경희,Cho, Eun-Kyung,Lee, Kyu-Man,Chung, Yong-Hoon,Cho, Yang-Ja,Kim, Kyung-Hee 대한소아감염학회 1996 Pediatric Infection and Vaccine Vol.3 No.1

Adenoviruses(Ad) are considered to be second only to rotaviruses as the most significant cause of gastroenteritis in young children in Korea and thus it is essential to know the full spectrum of Ad serotypes routinely present in stool specimens from symptomatic patients. Sixty-six Ad isolates and three questionable ones collected over a 2-year peiord were typed by standard microneutralization, restriction endonuclease digestion and PCR of viral DNA to be able to evaluate these assays comprehensively for their ability to identify Ad associated with gastroenteritis. A total of sixty-one isolates(88.4%) were typed: the predominant types were Ad type 41(Ad41)(26.2%), Ad2(19.7%), Ad40(14.8%), Ad5(9.8%), and Ad7(9.8%) which together accounted for almost 80% of the isolates. The remaining virus isolates were typed as Ad1, 31, 34, 3, 25 and a mixture of 40/41. The incidence of Ad31(4.9%) or Ad3(1.6%) was relatively insignificant. DNA restriction analysis(77.5%) proved to be better than serum neutralization but not so when compared to a PCR-based assay for identification of the enteric Ad serotypes(90%) in stool specimens. In this work, the PCR-based assay was evaluated as a tool for the rapid, yet highly sensitive identification of adenoviral DNA sequences in fresh clinical stool specimens.

고대 동아시아 불탑 구조체계를 통해 본 미륵사지석탑

조은경,박언곤,Cho, Eun-Kyung,Park, Eon-Kon 한국건축역사학회 2011 건축역사연구 Vol.20 No.5

This research was to suggest the types according to structural system of the pagoda in ancient East-Asia and analyze the pagoda to the west of Mireuksaji temple site by these types. It will be possible to understand consistently the relation of the various form of the pagoda. The results of this research were described separately as follows. 1. The Buddhist pagodas founded in the ancient East Asia can be categorized according to their structural system, which provide us with insight to understand the interrelationship of categories. The pagoda is mainly classified into three categories. The first consists of two structures, an internal and an external structure. The second exposes its internal structure to the outside, and the third has the external components changing into the internal ones. 2. Although the pagoda to the west of Mireuksaji Temple Site have an internal and an external structures, it actually solves the structural problem by adopting the masonry structure in the outside as well as in the inside. Especially in this structural consideration can be found in the stylobate and the foundation structure of the pillar. The plan of the pagoda to the west of Mireuksaji Temple Site was intended to reveal the plane of the post-lintel layered construction which has a member, a main pillar, and the inner space in the cube with stones.

$(ZrO_2)_x-(Tm_2O_3)_y$계의 전기전도도

조은경,정원양,김규홍,조승구,최재시,Eun Kyung Cho,Won Yang Chung,Keu Hong Kim,Seung Koo Cho,Jae Shi Choi 대한화학회 1987 대한화학회지 Vol.31 No.6

$ZrO_2$가 1,3 및 5mol%로 각각 도프된 $(ZrO_2)_x-(Tm_2O_3)_y$계의 전기전도도가 600~1,100$^{\circ}$C 및 $10^{-5}-2{\times}10^{-1}atm$의 산소분압하에서 연구되었다. 전기전도도를 온도의 함수로 도시한 결과, log ${\sigma}$ vs. 1/T의 기울기로 부터 구한 활성화에너지의 평균치는 1.51eV이다. 전기전도도의 산소분압의존성은 두 온도 영역에서 각각 다르며 고온영역에서 ${\sigma}{\alpha}PO_2^{1/5.3}$, 저온 영역에서 ${\sigma}{\alpha}PO_2^{1/10.7}$이다. 전기전도도의 온도 및 산소분압의존성으로 부터 고온영역에서 $(ZrO_2)_x-(Tm_2O_3)_y$계의 결함이 $V_{Tm}^{'''}$이며, electron hole이 전하운반체로 제안되었다. 저온영역에서는 이온과 hole이 전하운반체인 mixed conduction이 가능할 것으로 사료된다. Electrical conductivities of $(ZrO_2)_x-(Tm_2O_3)_y$ systems containing 1, 3 and 5mol% of $ZrO_2$ have been measured as a function of temperature and of oxygen partial pressure at temperatures from 600 to 1,100$^{\circ}$C and oxygen partial pressures from $10^{-5}$ to $2{\times}10^{-1}atm$. Plots of log conductivity vs. 1/T are found to be linear and average activation energy is 1.51 eV. The electrical conductivity dependences on PO$_2$ are different at two temperature regions, indicating ${\sigma}{\alpha}PO_2^{1/5.3}$ and ${\sigma}{\alpha}PO_2^{1/10.7}$ at high-and low-temperature regions, respectively. The defect of $(ZrO_2)_x-(Tm_2O_3)_y$ system is $V_{Tm}^{'''}$ and an electron hole is suggested as a carrier at high temperature region. At low temperature region, a mixed ionic and hole conduction is reasonable.

매생이 추출물의 angiotensin converting enzyme 및 α-glucosidase 활성 저해 효과

Eun Kyung Cho(조은경),Seul Ki Yoo(유슬기),Young Ju Choi(최영주) 한국생명과학회 2011 생명과학회지 Vol.21 No.6

해조류 매생이의 기능성을 증명하기 위하여 열수 또는 에탄올 추출하여 여러 가지 생리활성에 대하여 조사하였다. 우선, 매생이 열수와 에탄올 추출물의 항산화능을 조사하기 위하여 DPPH radical 소거능, SOD 유사활성을 측정하였다. 그 결과, 매생이 열수와 에탄올 추출물의 농도가 증가함에도 불구하고 낮은 증가율을 보였는데, 10 ㎎/㎖에서 DPPH radical 소거능은 각각 10.8, 62.4%, SOD 유사활성은 각각 13.8, 27.1%로 나타났다. 항고혈압 활성 측정에서는 1 ㎎/㎖의 매생이 열수와 에탄올 추출물이 각각 5.9, 49.7%의 활성을 보여 비교적 높은 효능이 매생이 에탄올 추출물에서 나타났다. 매생이 열수와 에탄올 추출물의 혈당 강하 효과는 α-glucosidase 저해능 분석으로 측정하였는데, 1 ㎎/㎖ 농도의 매생이 열수와 에탄올 추출물은 각각 1.4, 67.3%로써 비교적 높은 효능을 매생이 에탄올 추출물에서 보였다. 매생이의 숙취해소 효능은 ADH와 ALDH 활성증진에 매생이 열수와 에탄올 추출물이 미치는 영향을 조사함으로써 증명하고자 하였다. 그 결과, 매생이 열수와 에탄올 추출물의 농도가 증가함에도 불구하고 알콜 분해능 증가율이 낮게 나타났으며, 심지어 acetaldehyde 분해능은 관찰되지 않았다. Elastase 억제 효능 분석에서는 매생이 열수와 에탄올 추출물 10 ㎎/㎖에서 각각 75.9, 51.2%로 나타났다. Physiological activities of hot water (MHW) and 80% ethanol (MEH) extracts from Maesaengi (Capsosiphon fulvescens) were investigated in this study. For the evaluation of antioxidant activities for MHW and MEH, 2,2-diphenyl-1-pic-rylhydrazyl (DPPH) radical scavenging activity and superoxide dismutase (SOD)-like activity were measured. DPPH radical scavenging activity and SOD-like activity of MHW, and MEH were increased weekly in a dose-dependent manner, and were about 10.8, 13.8, 62.4, and 27.1% at 10 ㎎/㎖, respectively. The angiotensin converting enzyme (ACE) inhibitory activities of MHW and MEH were about 5.9% and 49.7% at 1 ㎎/㎖, respectively. The α-glucosidase inhibitory effect of MHW and MEH were about 1.4% and 67.3% at 1 ㎎/㎖, respectively. To determine the influence of MHW and MEH on alcohol metabolizing activity, the generating activities of reduced-nicotinamide adenine dinucleotide (NADH) by alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) were measured. Facilitating rates of ADH activity by MHW and MEH were increased weekly in a dose-dependent manner and ALDH activities were not detected. Elastase inhibitory activities of MHW and MEH were 75.9% and 51.2% at 10 ㎎/㎖, respectively.

현대 중국어 ‘NP₁+有+NP₂+VP’에 대한 小考

趙恩瓊(Cho Eun-kyung) 중국어문학연구회 2012 중국어문학논집 Vol.0 No.76

산겨릅나무 줄기 추출물의 항당뇨, 알코올 대사 효소 및 간 보호 활성

조은경(Eun Kyung Cho),정경임(Kyung Im Jung),최영주(Young Ju Choi) 한국식품영양과학회 2015 한국식품영양과학회지 Vol.44 No.12

본 연구에서는 간질환 치료제로 알려진 산겨릅나무 줄기 추출물의 새로운 기능성 소재로서의 개발을 위하여 생리활성을 탐색하였다. 산겨릅나무 열수 추출물의 총 페놀 함량은 198 mg tannic acid equivalents/g으로 나타났다. 항산화 활성은 DPPH 및 SOD 활성 측정 방법을 이용하여 분석하였으며, 산겨릅나무 열수 추출물의 농도 0.5 mg/mL에서 각각 89%와 82%의 활성을 나타내었다. 산겨릅나무 추출물의 혈당 강하 효과는 α-glucosidase 활성 억제 효과를 측정하였으며, 추출물 50 μg/mL 농도에서 75%의 억제 효과를 나타내었다. 이러한 결과는 지금까지 항당뇨 소재로 사용된 약용작물보다 높은 항당뇨 효과가 있는 것으로 사료된다. 알코올 분해 효소 alcohol dehydrogenase 및 aldehyde dehydrogenase 활성 촉진 효과는 농도 의존적으로 증가하였으며 5 mg/mL 농도에서 각각 260%와 123%를 나타내었다. Lipopolysaccharide에 의하여 유도된 nitric oxide(NO) 합성은 1 mg/mL 농도의 산겨릅나무 추출물을 처리함으로써 NO 합성률이 16.7% 정도 감소하였다. 산겨릅나무 추출물이 tacrine으로 유도된 Hep G2 세포주에 대하여 유의한 보호 활성을 나타냈다. 이러한 결과들은 산겨릅나무 추출물이 우수한 항당뇨, 항염증 효과 및 간세포 보호 효과가 높은 것으로 나타나 기능성 소재로서의 활용 가능성을 확인하였다. This study was carried out to investigate the antidiabetic, alcohol metabolism, anti-inflammatory, and hepatoprotective effects of Acer tegmentosum extracts (ATE). A. tegmentosum has been traditionally used as a folk medicine to treat hepatic disorders. The antioxidative activities of ATE were measured by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and superoxide (SOD) assay. DPPH radical scavenging and SOD activities of ATE were about 89% and 82.9% at 0.5 μg/mL, respectively. Alcohol dehydrogenase and acetaldehyde dehydrogenase activities were 118.0% and 177% at 2 mg/mL, respectively. α-Glucosidase inhibitory activity of ATE was 75% higher at 50 μg/mL and remarkably increased in a dose-dependent manner. Nitric oxide productions in macrophage RAW 264.7 cells stimulated by lipopolysaccharide was reduced to 16.7% by addition of ATE at 1 mg/mL. ATE showed significant protective effects against tacrine-induced cytotoxicity in Hep G2 cells at 100 μg/mL. Based on our results, we conclude that ATE may be used as a major pharmacological agent and anti-diabetic, anti-hepatitis, and anti-inflammatory remedy.

솔순 열수 추출물의 생리활성

조은경(Eun Kyung Cho),정보림(Bo Rim Jeong),최영주(Young Ju Choi) 한국식품영양과학회 2010 한국식품영양과학회지 Vol.39 No.11

본 연구에서는 솔순의 기능성을 규명하기 위해 열수 추출물을 대상으로 여러 생리활성과 아질산염 소거작용에 대하여 분석하였다. 우선, 솔순의 항산화 활성을 측정하기 위하여 DPPH, SOD 유사활성, XO 저해활성을 측정하였다. 그 결과 DPPH법을 통해 측정한 솔순의 항산화력은 2 ㎎/mL에서 71.4%의 radical 소거능을 나타내었으며, SOD 유사활성은 2 ㎎/mL 농도에서 85.4%로 비교적 높은 활성을 나타내었다. Xanthine oxidase 저해활성 측정 실험에서는 2 ㎎/mL에서 70.9%의 높은 저해활성을 나타내었다. 솔순 열수추출물의 아질산염 소거능 측정 실험에서는 pH 1.2와 3.0에서 53~59%, pH 6.0에서 40%의 소거능을 나타내었다. 항고혈압 측정실험에서는 시판되는 항고혈압제 captopril과 비교분석 하였는데, 0.1 ㎎/mL에서 93.0%였고 같은 농도의 솔순 열수 추출물은 14.6%의 낮은 저해율을 나타냈다. 하지만, 1 ㎎/mL에서 44.7%의 저해율을 나타내어 솔순 열수 추출물의 비교적 양호한 저해활성을 보였다. 혈당강하능의 지표로 α-glucosidase 활성 억제능을 분석한 결과 솔순 열수 추출물 3 ㎎/mL의 농도에서 43.3%의 저해활성을 나타냈으며, 주름 예방 효과의 지표로 elastase 활성 억제능을 측정한 결과 10 ㎎/mL의 농도에서 59.6%의 저해능을 보였다. 이상의 결과들은 솔순 열수 추출물의 우수한 생리활성을 증명하고 있는 것으로 천연의 건강 및 미용 소재로써 그 활용도가 높을 것으로 판단된다. This research was performed to determine the antioxidant activity, nitrite scavenging activity, and its inhibitory activity on angiotensin converting enzyme (ACE), xanthine oxidase, α-glucosidase, and elastase of hot water extract from pine bud (WPB). Antioxidant activity of WPB was measured by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and superoxide dismutase (SOD)-like activity. DPPH radical scavenging activity and SOD-like activity of WPB were remarkably increased in a dose-dependent manner, and were about 71.4 and 85.4% at 2 ㎎/mL, respectively. The xanthine oxidase and ACE inhibitory activities were about 70.9 and 51.9% at 2 ㎎/mL of WPB, respectively. Nitrite scavenging activity of WPB was about 59.1, 53.8, and 39.5% on pH 1.2, 3.0, and 6.0 at 2 ㎎/mL, respectively. The WPB also showed elastase and α-glucosidase inhibitory effects. These results revealed that pine bud have strong antioxidant activity and positive effects on the inhibition of xanthine oxidase, ACE, and elastase.

현대 중국어 ‘인가(人家)`의 사회적 직시 용법 연구

조은경 ( Cho Eun Kyung ) 한국중국언어학회 2016 중국언어연구 Vol.0 No.66

In this paper, a survey was conducted over the reference meaning of the word “renjia”, which is widely used in modern Chinese spoken language. In comparison with the Korean indefinite pronoun of “nam”, the paper discussed social deixis of “renjia”. In modern Chinese spoken language, “renjia” has its distinctiveness as it is different from other commonly used pronouns. “renjia” is usually used to indicate the third persons other than the speaker and the listener, but it can also be used to show different designative meanings according to different contexts. Under the category of social instruction in discourse and pragmatics, the potential semantic and pragmatic of “renjia” has the function of estrangement. In pragmatics, “renjia” may be regarded as the intimate and external groups. This usage is very similar to the indefinite pronoun “nam” in the Korean language. In Korean, ‘Nam` has both reference and non-reference usages, and it also has the distinction inside and outside the group. The word “nam” is often used to establish the relationship between two groups. At this point, Korean and Chinese have common features. It is hoped that the research in this paper can provide help to the teaching of Chinese as a foreign language.

Clostridium thermosaccharolyticum 에 의한 에탄올생산에 관한 연구

조은경(Eun Kyung Cho),이윤광(Yun Kwang Lee),변유량(Yu Ryang Pyun),유주현(Ju Hyun Yu) 한국미생물생명공학회 1985 한국미생물·생명공학회지 Vol.13 No.4

일자리사업 참여노인의 주관적 건강상태와 죽음불안에 관한 연구

조은경 ( Eun Kyung Cho ),김계하 ( Kye Ha Kim ) 이화여자대학교 간호과학연구소 2014 Health & Nursing Vol.26 No.2

purpose of the study was to examine the subjective health status and death anxiety of the elderly participating in senior job placement business. Methods: The subjects were 176 elderly aged 65 and over participating in senior job placement business in G city. Data were collected from November 4 to 13, 2013. PASW (Predictive Analytics SoftWare) statistics 18.0 version was used for descriptive analysis, t-test, one-way ANOVA, and Pearson correlation. Results: The mean scores of the subjective health status and death anxiety were 67.00 and 43.88, respectively. According to age, the number of disease and days of participation of job placement business, there were significant differences in the subjective health status. The subjective health status were not significantly correlated with death anxiety. Conclusion: These results show that senior job placement business gives positive effects in the health status of the elderly.