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백서 두개골에서 이종골 이식 후 치유에 관한 실험적 연구
조용석,김경원,Cho, Yong-Seok,Kim, Kyoung-Won 대한악안면성형재건외과학회 1999 Maxillofacial Plastic Reconstructive Surgery Vol.21 No.1
The purpose of this investigation was to evaluate the acceptability of the collagen-based xenograft ($Laddec^{(R)}$). Full thickness bone defects were prepared in the calvaria of the rats. In the experimental groups the bone defects were filled with a kind of collagen based xenograft. And bone defects, which left without filling, were used as control groups. Sequential sacrifice was performed at the 1st, 2nd, 4th, 8th, and 16th weeks of experiment. 1. At the 1st week of experiment, infiltration of chronic inflammatory cell was observed in all groups. In the experimental group, resorption of the xenograft was initiated. 2. At the 2nd week of experiment, infiltration of chronic inflammatory cells was decreased in all groups. In the experimental group, active resorption of xenograft and new bone formation from the periphery of the xenograft was observed. 3. At the 4th and 8th weeks of experiment, more resorption of the xenograft and new bone formation with calcification was observed in the experimental group. 4. At the 16th week of experiment, small bone trabecula was formed partially in the control group but that couldn't fill the whole bone defect. In the experimental group, more advanced resorption of xenograft and more new bone formation was observed. However mid portion of the xenograft was still remained without resorption. 5. From this experiment, we concluded that the collagen-based xenograft had some osteoconductive but no osteoinductive property. So the xenograft would be used for the bone defect filling material where rapid bone remodeling is not required.
조용석(Yong Seok Cho),김종원(Jong Won Kim),박진규(Jin Kyu Park) 대한구강악안면외과학회 1996 대한구강악안면외과학회지 Vol.22 No.2
Heterotopic islands of gastrointestinal mucosa have been observed throughout the entire gastrointestinal tract, from the oral cavity to the rectum, more commonly described in the duodenum, gallbladder, common bile duct, jejunum, Meckel s diverticulum, ileum, appendix, colon and rectum. Heterotopic gastrointestinal cysts of the oral cavity are extremely rare lesion. Although to our knowledge, only 29 cases of oral lesion have been reported to date in the world literature. We report a 23-year old male with a heterotopic gastrointestinal cyst in the mouth floor. The mass has been presented since birth and grown slowly without pain. The mass was removed with conservative surgical excision. The patient s postoperative course was uneventful and the follow-up to date shown no recurrence. The clinical and histopathological features of this rare lesion are presented with literature review.
FTP-75주행모드에 따른 Catalytic Converter의 Light-Off 예측
조용석(Yong-Seok Cho),김창래(Chang-Rae Kim),김득상(Duk-Sang Kim),이수원(Soo-Won Lee),명광희(Kwang-Hee Myung),주진석(Jin-Seok Choo) 한국자동차공학회 1997 한국자동차공학회 춘 추계 학술대회 논문집 Vol.1997 No.6_1
A computer code, named ESTAP (Exhaust System Thermal Analysis Program) and capable of running on IBM-PC compatibles, was developed to reduce the time and cost of exhaust system optimization. ESTAP solves one-dimensional transient heat transfer problems of exhaust systems. It can predict the surface temperature of exhaust pipes and exhaust gas temperature history at the inlet of a catalytic converter during the first 200 seconds of the FTP-75 test. Results showed that the exhaust gas temperature can be accurately predicted, and ESTAP is an effective tool to optimize exhaust systems.<br/>
조용석(Yong Seok CHO),김수경(Soo Kyoung KIM) 대한구강악안면외과학회 1992 대한구강악안면외과학회지 Vol.18 No.2
For the purpose of prevention, early diagnosis, improvement in treatment result and prediction in prognosis of oral cancer, clinico-statistical study was performed about clinical and histopathologic findings, treatment and survival rate of 150 cases of oral squamous cell carcinoma to have been diagnosed and treated in the Department of Oral and Maxillofacial Surgery, College of Dentistry, Seoul National University from the 1st of January, 1983 to the 31th of September, 1990. The results were as follows: 1. Oral squamous cell carcinoma occured more often in males than females with a ratio 3:1, and 64.0% occured between 50 to 69 years of age with a median 56.8 years. 2. In the site distribution, 41 cases (27.3%) of the mandibular alveolus and gingiva was the most frequently involved site, followed by the maxillary alveolus and gingiva with 34 cases (22.7%), the floor of mouth with 20 cases (13.3%), the buccal mucosa with 12 cases, the retromolar trigone with 8 cases, the maxillary sinus and the hard palate with each 4 cases, and the soft palate and lower lip with each 1 case. 3. In the TNM classification, T4 was prominent with 85 cases (56.7%), and NO was 68 cases (45.3%). In the clinical stage grouping, stage Ⅳ was prominent with 92 cases (61.3%). 4. In the treatment of primary lesion, the treatment consisted mainly of surgical therapy was prominent with 81 cases (54.0%), 32 cases (21.3%) of which were treated by radiation therapy or chemotherapy concurrently, 11 cases (7.3%) was treated by rediation therapy alone and 37 cases (24.7%) did not received any therapy. 5. Using Kaplan and Meier s product-limit method, overall 3 and 5-year survival rates without regarding to the stage were 36.5% and 29.0%. 6. 5-year survival rate according to the stage grouping was 71.4% for stage Ⅰ, 61.4% for stage Ⅱ, 43.5% for stage Ⅲ, 11.1% for stage Ⅳ. 7. 5-year survival survival rate according to the treatment was 44.7% for surgically treated cases, 18.4% for the cases of radiation therapy or chemotherapy. 6 and 12 months survival rates of patients who didn t received any therapy were 45.9% and 8.1%.