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Adipose stem cell exosome (ASCE)-based regenerative therapeutics & aesthetics
조병성 ( Byong Seung Cho ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.72 No.2
Exosomes, nano-sized extracellular vesicles, are the most important mediator for intercellular communication. Mesenchymal Stem Cell (MSC) - derived exosomes are known to have at least two major functions of regeneration and immunomodulation. For last years, ASCEs have been developed as cosmetics/cosmeceuticals and therapeutics as well. We have established a proprietary large scale production process of ASCE and tested the feasibility of ASCE with in vitro and in vivo models for skin rejuvenation and atopic dermatitis. Also, our collaborators have done the world’s first double-blinded and controlled clinical study for treatment of acne scar with topical application of ASCE in combination with fractional CO<sub>2</sub> laser. From all the studies, it was found that ASCEs can be very effective for skin rejuvenation/regeneration and atopic dermatitis through reconstitution of skin barrier functions. It was also found that ASCEs showed safe toxicological profiles.
할인점의 건축계획적 특성에 관한 연구 : 사회조사를 통하여 검증
조병성,이호진 대한건축학회 2000 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.20 No.1
The domestic market share is changing abruptly form the conventional store and the department store to the discount store in Korea, since the first discount store was opened in 1993. The discount store is prospected that it might be prosper for long and could become main stream of market pattern among market distributors because of the new trend of consumer's mass purchasing with vehicle. On this matter, this research concerned on the architectural characteristic analysis and synthesis about the discount store by means of surveying it that is built in 4∼5 years nearly.