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성음(聲音)과 언어(言語)에 관(關)한 문헌적(文獻的) 고찰(考察)
정희재,오태환,정승기,이형구,Jeong, Hee-Jae,Oh, Tae-Hwan,Jung, Sung-Gi,Rhee, Hyung-Koo 대한한방내과학회 1991 大韓韓方內科學會誌 Vol.12 No.1
The results of the investigation of literature were summerized as follows ; 1. Information of voice, the pharynx, the larynx, the epiglottis, the uvula and the hyoid bone were concerned. 2. In disorders of voice and speech, Lung channel, Stomach channel, Spleen channel, Heart channel, Liver channel, Kidney channel, Im channel (任脈), and Chung channel (衝脈) were concerned. 3. The disorders of voice and speech were showed as follows ; aphonia, ashasia, seong-shi (?嘶), seom-eo(?語) kwang-eo (狂語), jeong-seong (鄭?), dok-eo (獨語) and chak-eo (錯語). 4. The cause of Aphonia and Aphasia were freauently as follows ; abnormal rising of Liver energy (肝邪暴逆), excessive heart fire (心火太過), deficiency of heart-blood (心血太虛), apoplexy of heart spleen (心脾俱中風), consumption of lung fluid caused by heat evil (肺津被灼), deficiency of lung energy (肺氣虛寒) and dificiency of kidney energy (腎虛). 5. The cause of seom-eo, kwang-eo, Jeong-seong were as follows ; the heart of stomach (胃中熱), the heat evil attach the blood chamber (血人血室) and the consumption of healthy energy (精氣奪). 6. In disorders of voice and speech, flaceid tong with aphasia (舌?) and aphasia due to throat disease (喉?) were divided.
이식 후 신기능 상실로 혈액투석을 시작한 환자에서 뇌경색을 동반한 감염성 심내막염 1예
정희재 ( Hee Jae Jung ),유병철 ( Byung Chul You ),명유식 ( Yu Sik Myung ),김은정 ( Eun Jung Kim ),박무용 ( Moo Yong Park ),최수정 ( Soo Jeong Choi ),김진국 ( Jin Kuk Kim ),황승덕 ( Seung Duk Hwang ),고은석 ( Eun Suk Koh ),허균 ( 대한신장학회 2011 Kidney Research and Clinical Practice Vol.30 No.5
Infective endocarditis is a dreaded complication in dialysis or kidney transplantation patients, with high morbidity and mortality. Despite the improved early survival of the transplanted kidney with new immunosuppressive agents, the number of patients returning to dialysis after a failed renal allograft is increasing. There is no consensus on the optimal management of immunosuppression in patients with a failed allograft. Continued immunosuppression is associated with infection, and the rapid discontinuation of immunosuppression may lead to acute rejection. Therefore, it is important to taper the immunosuppression properly in patients with a failed renal allograft. We report on a hemodialysis patient with a failed renal allograft who had a cerebral infarction following infective endocarditis. The patient was treated successfully with antibiotics and valve replacement.
최준용,정희재,이건영,정승연,황준호,이형구,정승기,Choi, Jun-Yong,Jung, Hee-Jae,Lee, Kun-Young,Jeong, Seung-Yeon,Hwang, Joon-Ho,Rhee, Hyung-Koo,Jung, Sung-Ki 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.3
Objectives : The object of this study was to evaluate repeatability of portable spirometry and to determine an appropriate equation for predicted value. Materials and Methods : The subjects were 76 men and 45 women recruited from among Kyunghee University oriental medical students. Portable spirometry was performed via the procedure recommended in ATS guidelines. Repeatability of spirometry was checked against ATS repeatability standards and NHLEP QC grade. Percentage of predicted value of non-smokers was calculated through a Caucasian population-based regression equation(by Morris et al.) and Korean population based regression equation(by Kim et al.). These were compared. Result : 91.7% of subjects matched repeatability standards of ATS and 95% of subjects got interpretable NHLEP QC grades of A, B, and C. Mean percentage of predicted value by Morris et al. were as follows: Mean of FVC% was 90.86, FEV1% was 96.66, FEV1/FVC% was 107.48. Mean percentage of predicted value by Kim et al. were as follows. Mean FVC% was 92.38, FEV1% was 89.77, FEV1/FVC% was 96.95. Conclusions : Results of this study show that more than 90% of subjects meet repeatability criteria. This supports a role for the portable spirometer as a primary oriental medical office tool. Further, results are a verify that they Korean population-based predicted value equation is a more appropriate standard than the Caucasian population-based one, but a still more accurate standard is needed for the Korean adult population.
한 면에 ∧/∨형 리브가 있는 2벽면 수축 사각채널의 열전달 증가
이명성,유지의,정희재,최동근,하동준,고진수,안수환,Lee, Myung-Sung,Yu, Ji-Ui,Jeong, Hee-Jae,Choi, Dong-Geun,Ha, Dong-Jun,Go, Jin-Su,Ahn, Soo-Whan 한국마린엔지니어링학회 2016 한국마린엔지니어링학회지 Vol.40 No.4
양 벽면이 수축되는 채널에서 ${\vee}/{\wedge}$형 리브의 각도가 열전달에 미치는 효과를 실험적으로 조사하였다. 한 벽면에만 설치된 ${\vee}/{\wedge}$형 리브의 충돌 각은 각각 $30^{\circ}$, $45^{\circ}$, $60^{\circ}$ 그리고 $90^{\circ}$이다. 리브의 높이(e)는 10 mm 그리고 리브 간격(p)과 높이(e)비는 10으로 제작하였다. 길이가 1,000 mm인 시험 부는 입구의 단면적은 $100mm{\times}100mm$, 출구는 $50mm{\times}100mm$으로 제작하였다. 레이놀즈수가 22,000에서 75,000까지의 범위에서 실험을 수행하였다. 연구결과 전체적으로 레이놀즈 수가 높을수록 누셀트 수가 컸고, ${\wedge}$형 $45^{\circ}$ 리브가 가장 누셀트 수가 컸다. The effect of the rib angle-of-attack on heat transfer in the convergent channel with ${\vee}/{\wedge}$-shaped ribs was examined experimentally. Four differently angled ribs (a = $30^{\circ}$, $45^{\circ}$, $60^{\circ}$, and $90^{\circ}$) were placed to only the one sided wall. The ribbed wall was manufactured with a fixed rib height (e) of 10 mm and rib spacing (p)-to-height (e) ratio of 10. The convergent channel had a length of 1,000 mm and a cross-sectional areas of $100mm{\times}100mm$ at inlet and $50mm{\times}100mm$ at exit. The measurement was conducted for the Reynolds numbers ranging from 22,000 to 75,000. The results show that the Nusselt number is generally higher at higher Reynolds number and that an angle-of-attack of $45^{\circ}$ at the ${\wedge}$-shaped rib produces the greatest Nusselt number.
창출(蒼朮)이 천식 관련 Th1/Th2 세포 분비 cytokine에 미치는 영향
이정우,이형구,정희재,Lee, Jeong-Woo,Rhee, Hyung-Koo,Jung, Hee-Jae 대한한방내과학회 2007 大韓韓方內科學會誌 Vol.28 No.4
Background and Objective : Atractylodes japonica (AJ) is a commonly-used herbal medicine in Asian countries such as Korea, China and Japan. The present study was designated to evaluate the direct effects of AJ on helper T cell activities and on Th1/Th2 lineage development in vitro. Materials and Methods : Spleen cells from 8-week BALB/c mice were cultured in CR extracts containing medium without activation for 24 hours and with activation for 48 hours. CD4+ T cells were isolated and analyzed for mRNA expression levels of INF-$\gamma$, IL-4, T-bet and GATA-3 by RT-PCR and secretion cytokines levels of INF-$\gamma$, IL-2, IL-4, IL-5 and IL-10 by ELISA. Results : The results demonstrated that AJ had no mitogenic effects on unstimulated CD4+ T cells, but augmented CD4+T-cell proliferation upon activation with anti-CD3/anti-CD28 antibodies in a dose-dependent manner. AJ treatment significantly increased CD4+ T cell population and IFN-$\gamma$ expression was significantly enhanced, while IL-4 expression significantly decreased. In addition, in vitro Th1/Th2 polarization experiments revealed that AJ enhanced IFN-$\gamma$ secretion in Th1 cells, but reduced the IL-4 in Th2 cells in dose-dependent manner. Conclusion : These results suggest that AJ treatment could be a desirable alternative therapy for the prevention or correction of Th2 dominant pathological disorders, such as allergy and asthma.
Splenocyte, BMMC, eosinophil을 통해 본 단삼(丹蔘)이 천식 관련 염증세포에 미치는 영향
정승연,김진주,정희재,정승기,Jeong, Seung-Yeon,Kim, Jin-Ju,Jung, Hee-Jae,Jung, Sung-Ki 대한한방내과학회 2009 大韓韓方內科學會誌 Vol.30 No.1
Objectives : Asthma is a chronic inflammatory disorder of the airways by many cells such as mast cells, Th2 lymphocytes and eosinophile. The present study was aimed to evaluate the effects of Salviae miltiorrhizae (SM) on T cell cytokine production, mast cells. and eosinophils, Methods : We screened 13 herbs to find compounds with potential to control Th cytokine production. using concanavalin A (con A)-activated splenocyte cultures. Con A-activated $IFN-\gamma$ and IL-4 levels in supernatants of splenocyte cultures. Bone marrow derived mast cells (BMMC) were incubated with SM and then the expressions of membrane proteins of BMMC were analyzed by fluorescence activated cell sorter (FACS). BALB/c mice sensitized to ovalbumin (OVA) were challenged with aerosolized OVA for 6 weeks. During the last weeks some mice were treated with SM. Then eosinophils in bronchoalveolar lavage fluid (BALf) were counted and pathologic changes of lung tissue were observed with hematoxylin-eosin stain. Results : SM increased $IFN-\gamma$ level on splenocyte culture significantly. but had no significant effects on expressions of ICAM-1, CD62L, integrin $a_4$. c-kit, IL-3 receptors. CD11a, or IgE receptors of BMMC. SM treatment significantly inhibited eosinophil infiltrates in BALf and peribronchial lung inflammation. Conculusions : The present data suggested that SM may have an effect on Th cytokine secretion and eosinophils associated with asthma responses. Therefore SM might be of therapeutic value in treating asthma.
정승연,이재성,최준용,이건영,정희재,이형구,배현수,정승기,Jeong, Seung-Yeon,Lee, Jae-Sung,Choi, Jun-Yong,Lee, Kun-Young,Jung, Hee-Jae,Rhee, Hyung-Koo,Bae, Hyun-Su,Jung, Sung-Ki 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.1
Backgrounds : Gamichungsangboha-tang extract has been known to improve pulmonary functions and quality of life within four weeks of treatment. Cessation of treatment causes recurrence of symptoms and regression of pulmonary function and poorer quality of life. Long-term herbal therapy is difficult to maintain due to economic burden and other reasons. AF-365 is made with reduced dosage of Gamichungsangboha-tang extract. This study was designed to evaluate the effectiveness of AF-365 for maintenance therapy. Materials and Methods : The subjects consisted of 27 patients with asthma who had beed treated with AF-365 for four weeks. First, patients were treated with Gamichungsangboha-tang extract for four weeks. Second patients stopped herbal medicine for four weeks and after that they took AF-365. Pulmonary function test(PFT) was checked before and after four weeks of treatment. Quality of Life Questionnaire for Adult Korean Asthmatics(QLQAKA) was checked every two weeks from the beginning. The effects of AF-365 were analysed throughout the last four weeks. Results : Treatment of AF-365 for four weeks resulted in significant increase in PEFR%, QLQAKA. The QLQAKA of the step3, step4 group classified by Global initiative for asthma(GINA) showed significant improvement, and the QLQAKA of the step2 group showed no significant difference. In step3 group, PEFR% increased significantly. Conclusions : This study supports a role for AF-365 in maintenance of pulmonary function and quality of life, especially in persistent symptomatic asthmatics.