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만성폐색성폐질환 환자의 임상적 분류에 따른 운동생리의 차이
정만표(Man Pyo Jeong),현인규(In Gyu Hyun),송재훈(Jae Hun Song),정기석(Ki Suk Chung),한성구(Sung Koo Han),심영수(Young Soo Shim),김건열,한용철(Yong Chol Han) 대한내과학회 1991 대한내과학회지 Vol.40 No.4
N/A While patients with chronic obstructive pulmonary disease can be divided into two clinical groups as Pink Puffers (PP) and Blue Bloaters (BB), and whether or not knowledge on the physiologic changes during exercise in PP or BB and their differences might be useful to document the pathophysiology of PP and BB has been in debate. To evaluate the differences in exercise performance and physiologic changes during exercise between the two groups, pulmonary function test at rest, arterial blood gas analysis before and after exercise and incremental exercise test with bicycle ergometer on 16 PP and 9 BB patients with the same degree of airway obstruction in the resting state were conducted. The results were as follows. 1) There was no differences in sex, age, smoking history, forced vital capacity (FVC), forced expiratory volume in one second (FEV₁) and FEV₁/FVC between the two groups. 2) The anaerobic threshold (AT) was significantly lower in the PP group (p<0.05), while FEV₁, was not different. 3) There were no differences in the resting ventilatory response to O₂consupmption (VE/Vo₂) and to CO₂production (VE/Vco₂) between the two groups, but VE/ Vo₂and VE/Vco₂at maximal exercise were significant- ly nigher in the PP group (p<0.01). The increase in minute ventilation according to work load increment (△VE/△work 1oad), △VE/△Vo₂VE/Vco₂, were all significantly higher in the PP group (p<0.05, p<0.01, p<0.001, respectively). 4) There was a good correlation between △VE/△Vo₂, and △VE/△Vco₂(r = 0.782, p<0.001) in all patients. From the above findings. it was suggested that the PP were not only more sensitive in ventilatory response to the changes in the work load, O₂, or CO₂than BB, but that they also had lower exercise performance, and the ventilatory sensitivities to O₂, and CO₂were closely correlated with each other in all patients. However further study would be necessary for the identification of the pathophysiologic mechanisms of chronic obstructive pulmonary disease.
정상 한국인에서의 Isoniazid와 Rifampicin 약동학 연구
정만표 ( Man Pyo Chung ),김호철 ( Ho Cheol Kim ),서지영 ( Gee Young Suh ),박정웅 ( Jeong Woong Park ),김호중 ( Ho Joong Kim ),권오정 ( O Jung Kwon ),이종헌 ( Chong H. Rhee ),한용철 ( Yong Choi Han ),박효정 ( Hyo Jung Park ),김명민 대한결핵 및 호흡기학회 1997 Tuberculosis and Respiratory Diseases Vol.44 No.3
폐암절제술후 발생하는 사망 및 합병증의 예측인자 평가에 관한 전향적 연구
박정웅 ( Jeong Woong Park ),서지영 ( Gee Young Suh ),김호철 ( Ho Cheol Kim ),천은미 ( Eun Mee Cheon ),정만표 ( Man Pyo Chung ),김호중 ( Ho Joong Kim ),권오정 ( O Jung Kwon ),김관민 ( Kwan Min Kim ),김진국 ( Jin Kook Kim ),심영목 ( 대한결핵 및 호흡기학회 1998 Tuberculosis and Respiratory Diseases Vol.45 No.1
폐기능이 저하된 폐암환자에서 폐절제술후 합병중의 예측인자 평가에 관한 전향적 연구
박정웅 ( Jeong Woong Park ),정성환 ( Sung Whan Jeong ),남귀현 ( Gui Hyun Nam ),김호철 ( Ho Cheol Kim ),서지영 ( Gee Young Suh ),정만표 ( Man Pyo Chung ),김호중 ( Ho Joong Kim ),권오정 ( O Jung Kwon ),이종헌 ( Chong H. Rhee ) 대한결핵 및 호흡기학회 2000 Tuberculosis and Respiratory Diseases Vol.48 No.1
김혜정 ( Hye Jeong Kim ),배소영 ( So Young Bae ),성영경 ( Young Kyung Sung ),송송이 ( Song Yi Song ),전경만 ( Kyeong Man Jeon ),고원중 ( Won Jung Koh ),서지영 ( Gee Young Suh ),정만표 ( Man Pyo Chung ),김호중 ( Ho Joong Kim ),권 대한결핵 및 호흡기학회 2010 Tuberculosis and Respiratory Diseases Vol.69 No.5
Capillary hemangioma of the trachea is an extremely rare benign tumor in adults. We present the case of a 28-year-old woman with hemoptysis owing to a tumor of the proximal trachea. The tumor was removed by rigid bronchoscopy. The resulting specimens showed capillary hemangioma without any signs of malignant transformation. This presentation is the first case in Korea. Although tracheal capillary hemangioma is a rare disease, we should consider it as a possible cause of hemoptysis in the young adult.
통상성 간질성 폐렴과 비특이성 간질성 폐렴의 치료에 있어 Cyclophosphamide의 역할
전경만 ( Jeon Gyeong Man ),정만표 ( Jeong Man Pyo ),신성철 ( Sin Seong Cheol ),유창민 ( Yu Chang Min ),고원중 ( Go Won Jung ),서지영 ( Seo Ji Yeong ),김호중 ( Kim Ho Jung ),권오정 ( Kwon O Jeong ),김태성 ( Kim Tae Seong ),이경수 ( 대한결핵 및 호흡기학회 2003 Tuberculosis and Respiratory Diseases Vol.55 No.2
특발성 비특이성 간질성 폐렴 18례의 임상상 및 치료반응
강은해 ( Kang Eun Hae ),정만표 ( Jeong Man Pyo ),강수정 ( Kang Su Jeong ),안창혁 ( An Chang Hyeog ),안종운 ( An Jong Un ),한정호 ( Han Jeong Ho ),이경수 ( Lee Gyeong Su ),임시영 ( Im Si Yeong ),서지영 ( Seo Ji Yeong ),김호중 ( Kim 대한결핵 및 호흡기학회 2000 Tuberculosis and Respiratory Diseases Vol.48 No.4
김효진(Hyo Jin Kim),정만표(Man Pyo Jeong),허대석(Dae Seog Heo),방영주(Yung Jue Bang),한성구(Sung Koo Han),심영수(Young Soo Shin),김노경(Noe Kyeong Kim),김건열(Keun Youl Kim),한용철(Young Chol Han),김주현(Joo Hyun Kim),박찬일(Charn Il 대한내과학회 1994 대한내과학회지 Vol.46 No.2
N/A Background: This study was performed to find out the natural history of lung cancer in Korea. Method: Week studied retrospectively 764 patients with pathologically proven lung cancer from January 1980 to December 1984. We analysed the age and sex distribution, initial symptoms before diagnosis, first method yielding histologic diagnosis, cell types of lung cancer, initial stage of lung cancer, schema of overall patients, and survival of lung cancer patients. Result: 1) The overall male to female ratio was 4.7:1, and the age distribution ranged from 21 to 82 years, and the median age of overall patients was 58 years. 2) Histologic classification revealed that the most prevalent type was squamous cell carcinoma (375 cases, 49.1%), followed by small cell carcinama (189 cases, 24.7%), adenocarcinoma (134 cases, 17.5%), and large cell carcinoma (44 cases, 5.8%). 3) In non-small cell lung cancer 88% were stage III, therefore curative operation was done in only 8% of all cases, but in small cell lung cancer 66% were limited disease. 4) Median survival of overall patients was 5.8 months. 5) There was quite difference in survival between stage. In non-small cell long cancer, median survival of stage I was 41 months, median survival of stage II was 13 months and median survival of stage III was 5 months. In small cell lung cancer, median survival of limited disease was 10.4 months and median survival of extended disease was 2.8 months. Conclusion: The prognosis of patients with lung cancer was very grave. In order to increase the survival rate of lung cancer, earlier diagnosis of lung cancer is urgently needed.