http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
치위생과 학생들의 임상실습기관의 환경요인 스트레스와 스트레스 량의 관련성
류혜겸,위혜진,정동은,Ryu, Hae-Gyum,Wi, Hye-Jin,Jeong, Dong-Eun 한국임상보건과학회 2017 한국임상보건과학회지 Vol.5 No.3
Purpose : This study was conducted to provide basic data on the relationship between environmental factors causing stress in clinical practice institutions and stress levels of dental hygiene students. Methods : The research subjects totaled 207 and it was analyzed with structured questionnaires. The collected data were analyzed using an IBM SPSS ver. 20.0. Results : The environmental factors causing stress according to the status of clinical practice institutions was statistically and significantly different in the case of Busan practice areas (p<0.01), dental university hospitals (p<0.001), attendance times prior to 8am (p<0.001), quitting times that surpassed 8pm (p<0.01), and the number of dentists exceeding 4 (p<0.01). It was found to affect the stress level of students when individuals had to stand for a long period of time(p<0.001, ${\beta}=0.254$) and with the use of unfamiliar tools and equipment(p<0.05, ${\beta}=0.178$). Conclusions : As a result of the research conducted, it should be concluded that dental clinics should provide rest areas for individuals to focus on clinical practice. In addition, it is necessary to develop a systematic program that enables students to communicate with students at any time during the training period.
조윤정 ( Yun Jeong Jo ),정영걸 ( Young Kul Jung ),정동해 ( Dong Hae Chung ),권오상 ( Oh Sang Kwon ),김연수 ( Yun Soo Kim ),최덕주 ( Duck Joo Choi ),김주현 ( Ju Hyun Kim ) 대한간암학회 2012 대한간암학회지 Vol.12 No.1
Hepatocellular carcinoma (HCC) is one of the most important causes of cancer death in South Korea. Approximately two thirds of the patients are diagnosed in the advanced stage with multiple metastasis and underlying liver dysfunction, so they are not suitable to undergo curative resection. Small HCC has no consensus about diagnostic criteria but became known early stage HCC that means good prognosis. Cases of small HCC have been increasing with the progress of diagnostic methods. We experienced a case of incidentally found small HCC less than 1 cm from liver cirrhosis by liver dynamic imaging, so reported it.
김나래 ( Na Rae Kim ),정동해 ( Dong Hae Chung ),백정흠 ( Jeong Heum Baek ),박연호 ( Yeon Ho Park ),경희은 ( Hee Eun Kyung ),노미숙 ( Mi Sook Roh ),하승연 ( Seung Yeon Ha ) 대한장연구학회 2010 Intestinal Research Vol.8 No.2
Squamous cell carcinoma of the rectum is extremely rare. Herein we report two cases of rectal squamous cell carcinoma. Case 1 was a 44-year-old Korean female presenting with abdominal pain and rectal bleeding for 3 months before her hospital visit. A colonoscopic examination revealed an ulcerated rectal mass 8 cm proximal to the anal verge. Chemoradiotherapy was administered following Hartmann``s procedure in case 1. The patient remained alive during 19 months of follow up. Case 2 was a 43-year-old Korean female who had severe constipation for 2 months. A barium enema and computed tomography of the pelvis showed a rectal mass adherent to the sacrum. Based on the results of a colonoscopic biopsy, a diverting colostomy was performed in case 2, with no further treatment. The pathologic findings showed that both tumors were composed of oval-shaped cells with abundant eosinophilic cytoplasm and intercellular bridges with keratin pearls, and thus were diagnosed as well-differentiated squamous cell carcinoma. Neither of the cases showed evidence of HPV infection. The pathogenesis of rectal squamous cell carcinoma has not been clarified. Herein we report two cases of rectal squamous cell carcinoma and briefly discuss the possible histogenesis. (Intest Res 2010;8:172-176)
정종철(Jong-Cheol Jeong),최세훈(Se-hoon Choi),송민석(Min-Soek Song),전창훈(Chang-Hun Jun),김현민(Hyun-Min Kim),정동해(Dong-Hae Jeong) 대한구강악안면외과학회 2003 대한구강악안면외과학회지 Vol.29 No.3
Kaposi s sarcoma was first descrided by Kaposi in 1872 as an idiopathic multiple hemorrhagic sarcoma. Its clinical features revealed to be erythematous red or purple macule started out, and developing into palpable dome-shaped nodules. Etiology is not defined to detail at present. Kaposi s sarcoma is classified to 4 categories; Classical, African, Epidemic and Transplant type. Epidemic or AIDS categories is found approximately 20 % of all AIDS and has strong predilection for head and neck region. The first case of Kaposi s sarcoma observed in patients with kidney transplants was reported in 1969. Kaposi s sarcoma now accounts for 5% of all tumors associated with transplanted patients and alteration of the immunosuppression may have played a key role in these recipients. The most common site of Kaposi s sarcoma in transplanted patients are extremities but rare in head and neck area. We report a case of Kaposi s sarcoma on the hard palate in the kidney transplantation patient.
폐흡충의 이배체와 삼배체 vasa 유전자 분석 및 특징
이근희,유학선,허재원,유성숙,최선희,박상균,이선주,정동일,공현희,옥미선,정해진,Lee, Keun-Hee,Yu, Hak-Sun,Hur, Jae-Won,Yu, Sung-Suk,Choi, Sun-Hee,Park, Sang-Kyun,Lee, Sun-Joo,Chung, Dong-Il,Kong, Hyun-Hee,Ock, Mee-Sun,Jeong, Hae-Jin Korean Society of Life Science 2007 생명과학회지 Vol.17 No.4
폐흡충은 국내를 비롯한 아시아에서 폐흡충증을 일으키는 중요한 기생충이다. 이러한 폐흡충은 이배체 와 삼배체가 국내에 알려져 있다. 이배체 폐흡충은 양성생식을 하고 삼배체 폐흡충은 단위생식을 하는 것으로 알려져 있다. 그러나 이러한 원인에 대하여서는 알려진 바가 없다. 생식유전자 중 초파리에서 최초 분리되었고 포유동물에서도 그 기능이 밝혀진 vasa 유전자가 가장 유명하다. 이 유전자는 생식세포의 분화에 관여하며 종에 따라서는 정자생성에도 관여하는 것으로 알려져 있다. 이번 연구는 삼배체 폐흡충의 단위생식과 vasa 유전자와의 관계를 규명해 보고자 하였다. 폐흡충의 이배체와 삼배체 성충으로부터 vasa 유전자 전체의 염기서열을 얻을 수 있었다. 두 염기서열의 경우 8개의 ATP-binding domain이 관찰되었고 helicase가 결합할 것으로 예상되는 RGG motif도 관찰되었다. 총 622아미노산 서열로 구성될 것으로 보이며 이배체는 69.018 kDa, 삼배체는 68.930 kDa 크기의 단백질을 만들 것으로 예상되었다. Vasa 재조합 단백질은 GST와 fusion되어 93 kDa 크기에서 관찰되었다. mRNA의 발현은 이배체에 비해 삼배체가 다소 높았다. Anti-Pw-VASA항체를 이용한 면역조직화학법을 수행한 결과 이배체와 삼배체는 다른 기관에서는 면역반응력을 보이지 않고 고환에서만 면역반응력을 볼 수 있었다. 결과를 종합해 보면 vasa 유전자는 이배체 삼배체 모두 가지고 있었으며 정상적으로 발현되었다. In this study, we isolated, characterized, and compared the vasa homologous genes of diploid and triploid Paragonimus westermani and localized VASA homologous proteins in both lung fluke types. Open reading frames of Pw-vasa-2n and Pw-vasa-3n were of 1812 bp, and encoded deduced proteins of 622 amino acids with calculated molecular weights of 69.0 kDa and 68.9 kDa and pI's of 9.11 and 9.03, respectively. A comparison of these two VASA deduced protein sequences showed that only 6 of the 622 amino acids differed. The deduced sequences of Pw-VASA-2n and Pw-VASA-3n contained eight consensus sequences characteristic of the DEAD-box protein family and their N-terminal regions contained four arginine-glycine-glycine (RGG) motifs. These two lung fluke VASA-like proteins were more similar to those of other VASA proteins than to those of other DEAD-family proteins isolated from several organisms (planarian, zebra fish, mouse, and human). vasa homologous gene transcription and VASA protein expressions in triploid type lung flukes was slightly stronger than in the diploid type. Immunostaining showed that testes and a portion of the ovaries of both diploid and triploid lung flukes reacted strongly to anti-Pw-VASA antibody.
Glufosinate 중독 환자의 신경학적 예후 인자로서 APACHE II Score의 유용성
유대한 ( Dae Han Yoo ),이정원 ( Jung Won Lee ),최재형 ( Jae Hyung Choi ),정동길 ( Dong Kil Jeong ),이동욱 ( Dong Wook Lee ),이영주 ( Young Joo Lee ),조영신 ( Young Shin Cho ),박준범 ( Joon Bum Park ),정혜진 ( Hae Jin Chung ),문형 대한임상독성학회 2016 대한임상독성학회지 Vol.14 No.2
Purpose: The incidence of glufosinate poisoning is gradually increasing, and it can be fatal if severe poisoning occurs. However, factors useful for predicting the post-discharge neurological prognosis of patients who have ingested glufosinate have yet to be identified. Our objective was to evaluate the utility of the acute physiology and chronic health evaluation (APACHE) II score measured in the emergency department for predicting the neurological prognosis. Methods: From April 2012 to August 2014, we conducted a retrospective study of patients who had ingested glufosinate. The outcome of the patients at discharge was defined by the Cerebral Performance Category Score (CPC). The patients were divided into a good prognosis group (CPC 1, 2) and a poor prognosis group (CPC 3, 4, 5), after which the APACHE II scores were compared. The Hosmer-Lemeshow test and the area under the receiver operating characteristic (ROC) curve from patients determined calibration and discrimination. Results: A total of 76 patients were enrolled (good prognosis group: 67 vs poor prognosis group: 9). The cut-off value for the APACHE II score was 12 and the area under the curve value was 0.891. The Hosmer and Lemeshow C statistic χ2 was 7.414 (p=0.387), indicating good calibration for APACHE II. Conclusion: The APACHE II score is useful at predicting the neurological prognosis of patients who have ingested glufosinate.
Gastrointestinal autonomic nerve tumor in the lower rectum
Sung Won Park(박성원),Jung Nam Lee(이정남),Dong Hae Jung(정동해),Jeong-Heum Baek(백정흠) 대한종양외과학회 2015 Korean Journal of Clinical Oncology Vol.11 No.1
Gastrointestinal autonomic nerve tumor (GANT) in the rectum is a subset of gastrointestinal stromal tumor (GIST). It’s a very rare mesenchymal tumor with neuronal differentiation of gastrointestinal tract. We experienced a 34-year-old female patient with GANT in the lower rectum. She was referred to our hospital owing to rectal bleeding, but didn’t have other symptoms such as abdominal pain and constipation. On digital rectal examination, a round and smooth submucosal tumor at posterior wall of the rectum was palpated approximately 5 cm above the anal verge. The mass measured approximately 5 cm in diameter and was not fixed to the underlying structures. Colonoscopy, abdomino- pelvic computed tomography scan, and core needle biopsy were performed. Given the impression of GIST, it was assumed that the patient underwent low anterior resection with double stapling technique. The tumor, a yellow-grayish colored mass, was homogenous and didn’t have hemorrhagic necrosis. Diagnosis of GANT was based on histological, immunohistochemical staining, and electron microscopy. The patient did not receive any adjuvant therapy and was discharged without complications on the tenth postoperative day.