조선소 근로자의 직종과 혈청 암배아성 항원 농도와의 관련성

정갑열 ( Kap Yeol Jung ),김정원 ( Jung Won Kim ),예병진 ( Byeong Jin Ye ) 한국산업위생학회 2013 한국산업보건학회지 Vol.23 No.2

Objectives: The purpose of this study was to clarify the association between serum carcinoembryonic antigen (CEA) and type of work in the shipbuilding industry. Methods: 1,072 final study subjects were admitted to a general hospital from April through July 2010 for the purpose of medical examination. Data on general characteristics such as age, smoking history, alcohol history and exercise habits was gathered through structured self-administered questionnaires. Information on job factors was collected from a medical examination, by interview and through company personnel data. Serum CEA levels were measured after eight hours`` fasting and were analyzed by a radioimmunoassay. Results: On univariate analysis, the mean serum CEA level was significantly higher among married (p=0.02), older age (p<0.01), longer work time (p<0.01), smokers (p<0.01), lower education (p<0.01), and indirect and direct exposure groups (p<0.01). On multiple regression analysis, serum CEA level was influenced by smoking (p=0.001), duration of work (p=0.019), and direct exposure group (p<0.001). However, among the direct exposure group, serum CEA level was not significantly different between welding, mounting, electro-device constructive work, grinding and cleaning, and painting. Conclusions: The goal of this research was to determine if there were differences between serum CEA levels according to occupational role among shipyard workers. The direct exposure group of shipyard workers had a relatively higher level of serum CEA than did the indirect exposure group and office workers, most likely due to occupational exposure.

소방관의 근골격계 증상과 직무 스트레스에 관한 연구

김정만(Jung Man Kim),서병성(Byung Seong Suh),정갑열(Kap Yeol Jung),김동일(Dong Il Kim),김원술(Won Sool Kim),조한석(Han Seok Cho),김진욱(Jin Wook Kim),권재(Jae Kwon),윤동영(Dong Young Yoon),김정일(Jung Il Kim) 한국항공우주의학협회 2006 항공우주의학회지 Vol.16 No.2

소방관의 근골격계 증상과 직무 스트레스에 관한 연구

김정만 ( Jung Man Kim ),서병성 ( Byung Seong Suh ),정갑열 ( Kap Yeol Jung ),김동일 ( Dong Il Kim ),김원술 ( Won Sool Kim ),조한석 ( Han Seok Cho ),김진욱 ( Jin Wook Kim ),권재 ( Jae Kwon ),윤동영 ( Dong Young Yoon ),김정일 ( Jung 한국산업위생학회 2007 한국산업보건학회지 Vol.17 No.2

Firemen are directly exposed to various harmful chemicals, physical factors and mental stress during rescue and firefighting. In fire extinguishing, unstable posture, poisonous gas, dust, high temperature and heavy equipments are possible hazardous factors. The alertness for emergency, shift work, job strain and stress are also possibly hazardous. Therefore, this study aimed to investigate the prevalence of musculo-skeletal symptoms and job stress and to determine risk factors in firemen. This study was carried out in a group of 226 firemen in Busan City, Korea. Standardized Nordic Questionnaire was used to investigate the prevalence of musculo-skeletal symptoms and Psycho-social Well-being Index (abbreviated PWI) was used to investigate the prevalence of job stress. General and occupational characteristics were included education, marital status, alcohol and smoking history, working duration, and work shift system. Body mass index (BMI) scores were calculated by physical examination including height and weight. Concerning musculo-skeletal complaints, the commonest site was neck, and shoulder, lower back, upper back were the next. Complaint site above one area of body was about 80%. From multiple logistic regression analysis, working duration was significant variable in musculo-skeletal symptoms. Odds ratio were 15.4 in working duration. About 16.8% was high risk stress group. From multiple logistic regression analysis, shift work and alcohol drinking were significant variables in PWI scores. Odds ratios were 2.25 in shift work. Accordingly, interventions are needed for health promotion of long term and shift worker.

우리나라에서의 지역의 물질적 결핍수준과 15-64세 인구 표준화사망비의 관계

정백근,정갑열,김준연,문옥륜,이용환,홍영습,윤태호,Jeong, Baek-Geun,Jung, Kap-Yeol,Kim, Joon-Youn,Moon, Ok-Ryun,Lee, Yong-Hwan,Hong, Young-Seoub,Yoon, Tae-Ho 대한예방의학회 2006 예방의학회지 Vol.39 No.1

Objectives: This study was performed to investigate the relationship between regional material deprivation and the standardized mortality ratios(SMRs) of community residents aged 15-64 in Korea. Methods: SMRs were investigated using the registered death data from 1995 to 2000 that was obtained from the Korean National Statistics Office with the denominators being drawn from the 1995 to 2000 census. Material deprivation was measured using the Townsend score that was calculated from the 1995 to 2000 census. The relationship between the regional material deprivation and the SMRs of the community residents aged 15-64 was investigated by using ANOVA, Spearman's rank correlation analysis and Pearson's correlation analysis. The trends in mortality inequality were investigated using the concentration index. Results: On the ANOVA, the SMRs of the men and women residents in the least deprived areas were the smallest and those in the most deprived areas were the largest. Spearman's rank correlation analysis, Pearson's correlation analysis and the concentration index revealed that significant positive relationships exist between the regional material deprivation and the SMRs of the community residents aged 15-64. Conclusions: This study suggests that there are mortality inequalities among the communities in Korea and part of this difference is due to the material deprivation of the community. Strategies aimed at reducing mortality inequalities among the communities will be needed to address economic inequalities. Further studies are needed to explore the mechanisms of how the regional deprivation influences on health and how the other factors of the community influence on the health of the community residents.

부산지역 주민의 자궁경부암 수검과 관련이 있는 요인

최귀선,이덕희,정갑열,손지언,장태원,김윤규,신해림,Choi, Kui-Son,Lee, Duk-Hee,Jung, Kap-Yeol,Son, Ji-Eun,Jang, Tae-Won,Kim, Yoon-Kyu,Shin, Hai-Rim 대한예방의학회 2004 예방의학회지 Vol.37 No.2

Objectives : Cervical cancer is the second most frequent cancer among women in Busan. The Pap smear test could have a significant effect on detecting cervical cancer, and enhancing their rate of use is an important strategy for reducing the incidence and mortality of cervical cancer. This study aimed to evaluate the factors associated with the past use of the Pap smear test in Korean women. Methods : A population-based survey was carried out in Busan between November 1999 and March 2000. 1,673 participants were randomly selected from 2,684 women in Busan, using a 2-stage cluster sampling method, and interviewed in their homes. Their socio-demographic characteristics, smoking, drinking, familial cancer history, Pap smear screening history, reproductive and menstrual factors, sexual habits and use of contraceptive methods data were collected by a trained interviewer using a questionnaire. The use of the screening test was defined by a self-report from the participants on how many times they had had a Pap smear test in their lifetime, and when they had received their latest examination. Results : Of the 1,673 respondents (62.3% response rate), 57.6% had had a Pap smear test during her life (mean number, 2.3). Among the health examination participants(1,064), 961(90.3%) reported having sexual experience and 70.9% of these had had a Pap smear test. In a multiple logistic regression analysis, statistically significant relationships were observed for age groups and the Pap smear test rate (odds ratio, OR for 35-44 years=2.45; OR for 45-54 years=3.41; OR for 55 years=2.60; reference, under 34 years). The married or cohabiting women were more likely to have used the Pap smear test than those separated or widowed (OR=1.73). Among the reproductive behavioral measures, the number of births (OR for 3 births=4.22; OR for 2 births=3.95; OR for 1 births=3.38; reference, 0 births) and husband's extra-marital affairs (OR=1.50) were associated with the rates of use of Pap smear tests. Conclusion : It appears that the most important contributing factors to cervical cancer screening were age, marital status and number of births. A positive association was also observed for the husband's extra-marital affairs. This study enabled us to systematically assess the relationship between Pap smear rates and risk factors for cervical cancer. It is hoped that this study will make a significant contribution to the accumulating scientific evidence on the identification of factors associated with cervical cancer screening in Korea.

ACE 삽입 및 결손 유전자 다형성과 HDL 콜레스테롤과의 관련성

유창훈,곽종영,김나영,노미숙,정갑열,이용환,김정만,김준연,홍영습,You, Chang-Hun,Kwak, Jong-Young,Kim, Na-Young,Roh, Mee-Sook,Jung, Kap-Yeol,Lee, Yong-Hwan,Kim, Jung-Man,Kim, Joon-Youn,Hong, Young-Seoub 대한예방의학회 2006 예방의학회지 Vol.39 No.6

Objectives : The purpose of this study is to evaluate the association of the angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism with cardiovascular disease risk factors. Methods : Out of a total of 608 middle-aged adults who visited local health centers, 424 subjects (104 male, 320 female) who had not been diagnosed with hypertension, diabetes mellitus, or hyperlipidemia were included in this study. ACE genotypes were determined in all subjects by polymerase chain reaction methods. Results : Statistical differences in high-density lipoprotein (HDL) cholesterol levels according to ACE genotype were observed using ANOVA (p<0.05), but no differences were found in other cardiovascular risk factors. Specifically, men with the DD and DI genotypes had significantly lower HDL cholesterol levels than those with the 11 genotype based on the LSD multi-comparison test (p<0.05). Conclusions : In men, the D-allele of the ACE I/D polymorphism was significantly associated with reduced HDL cholesterol levels. In the future, larger studies are needed to confirm this relationship between ACE I/D polymorphism and HDL cholesterol.

농촌지역 주민의 건강관련 행위와 질병이환과의 관계

송주복,이부옥,신해림,정갑열,김준연,Song, Jue-Bok,Rhee, Boo-Ouk,Shin, Hai-Rim,Jung, Kap-Yeol,Kim, Joon-Youn 대한예방의학회 1997 Journal of Preventive Medicine and Public Health Vol.30 No.2

This research was carried out to determine the performance rate of health related practices, to measure the agreement between morbidity by doctor's diagnosis and morbidity by subject' self-reported and the degree of association between health related practices and morbidity rate by doctor's diagnosis, to identify their effects on morbidity among rural area populations. The data were gathered by volunteer residents (over the age of 20) of Haman Myeon, Haman Gun, Kyeongsangnam Do in Korea, from June 10, 1993 to June 12, 1993 (369 male and 516 female). Face to face interview, lab, chest P-A, EKG and physical examination were completed. Descriptive statistics, agreement analysis and multiple logistic regression procedures were employed for analyses. The results of the study were summarized as follows : 1) Age adjusted morbidity rates by doctor's diagnosis and self-reported were 38.5% (male:37.3%, female:36.5%), 26.4% (male:33.3%, female:27.5%), respectively. Kappa coefficient between morbidity by doctor's diagnosis and morbidity by self-reported was 0.21 (male:0.21, female:0.22). 2) The frequency of disease by doctor's diagnosis was as follows: hypertension(15.3%), gastritis (9.6%), diabetes mellitus (8.5%), live. disease (8.1%), and degenerative arthritis (6.2%) in the study population. 3) Order of health practice performance rate was as follows: Males-normal body weight (62.1%), non-heavy alcohol consumption (57.5%), 7-8 hours of sleeping (50.1%), non-smoking (21.7%), and exercise (19.8%). Females- non-heavy alcohol consumption (97.3%), non-smoking (84.7%), normal body weight (57.8%), 7-8 hours of sleeping (45.0%), and exercise (9.9%). 4) There was no significant relationship between health related practice and morbidity except exercise among health related practices. 5) Health related practice index which was recategorized by high, medium, and low had effects on the probability of developing morbidity.

일부 우리나라 성인의 대사성증후군의 유병률과 허리둘레 예측치

홍영습,정백근,박용우,박종태,정갑열,김준연,김병권,Hong, Young-Seoub,Jeong, Baek-Geun,Park, Yong-Woo,Park, Jong-Tae,Jung, Kap-Yeol,Kim, Joon-Youn,Kim, Byoung-Gwon 대한예방의학회 2004 예방의학회지 Vol.37 No.1

Objectives : The purpose of this study was to estimate the prevalence of metabolic syndrome, as defined by the ATP III report, in some Korean adults and use the Asian-Pacific proposed waist circumference to investigate waist circumference in some Korean adults using ROC curves. Methods : Study subjects were seventy-five thousands and ninety one persons(47,979 men and 27,111 women) who were selected among the patients who visited hospital for health evaluation from January 2000 to December 2001. All subjects were measured by height, weight, waist and hip circumferences, blood pressure and blood chemistry(lipid profile). Results : The mean age was $41.6{\pm}8.5$ years in men, $41.1{\pm}10.4$ years in women(p<0.05). Body mass index was in the normal range in 35.3% of men, and 55.9% of women. In both men and women, blood pressure, blood sugar, total cholesterol and triglyceride were positively correlated with BMI. waist circumference, and Broca's index(p<0.01). However HDL. choloesterol was correlated negatively (p< 0.01). Using ROC curve, the calculated waist circumferences were 84 cm in men(sensitivity 61.4% and specificity 64.1%) and 74 cm in women(sensitivity 65.0% and specificity 73.2%). The age adjusted prevalences of the metabolic syndrome as defined by NCEP ATP III were different for men(6.4%) and women(14.6%). The prevalence increased from 1.2% among participants aged 20 through 29years to 15.0% among participants aged over 60years in men(p<0.05) and from 1.6% to 27.4% respectively, in women. The age adjusted prevalences, as defined by using the waist circumference that was recommended by WHO's regional office for the western Pacific, were 10.6% in men and 18.5% in women. The age adjusted prevalences, as defined by using the waist circumference that was calculated by the ROC curves, were 17.1% in men and 22.4% in women. And All prevalences were increased following increased BMI and Broca's index. Conculsions : The prevalence of metabolic syndrome in some Korean adults was lower than that in western adults. Nevertheless because waist circumference was differed among race and region, application of the same criteria was not proper. Morcover, a higher awareness was required in women, because the prevalence of metabolic syndrome was rapidly increased with increment of age.

일개 도시 일부 청년층(16-24세)의 B형, C형 간염에 관한 혈청역학적 연구

주영희,오진경,김동일,이덕희,김병권,김정일,정갑열,신해림,Ju, Young-Hee,Oh, Jin-Kyoung,Kim, Dong-Il,Lee, Duk-Hee,Kim, Byeong-Kweon,Kim, Jung-Il,Jung, Kap-Yeol,Shin, Hai-Rim 대한예방의학회 2004 예방의학회지 Vol.37 No.3

Objectives : To investigate the prevalence of hepatitis B and C virus infections and determine the associated risk factors among young adults in Busan, Korea, which is known to have a high incidence of liver cancer. Methods : The study population consisted of volunteer participants in a health survey during 2002, which included 1,350 students (515 males and 835 females) aged between 16 and 24 years, from three different schools in Busan. The participating students were asked to fill in a self-administered questionnaire which included lifestyle habits and risk factors of hepatitis. Sera obtained from the participants were studied for HBsAg, anti-HBs, and Anti-HCV by enzyme immunoassay (EIA) method and for liver function tests. Results : Among the study subjects (N=1,350), the seropositivities of HBsAg 7.9%(95% CI=7.8-8.0), 7.6%(95% CI=7.6-7.7) in male and 8.1%(95% CI=8.0-8.2) in female. And the seropositivity of Anti-HBs was 69.7%(95% CI=69.0-70.4), 70.5%(95% CI=69.8-71.2) in male and 69.2%(95% CI=68.5-69.9) in female. The seropositivity of Anti-HCV was 0.4%, 0.2% in male and 0.5% in female. The seropositivity for HBsAg in the subjects not having a hepatitis B vaccination history was twice(95% CI=1.0-4.4) that of those that did. Also, the seropositivity for HBsAg in subjects having experienced sexual intercourse was 1.7 times (95% CI=0.9-3.0) that of the subjects who had not. Conclusions : The present study confirmed the high prevalence of HBsAg seropositivity and sexual transmission of HBV among adolescents and young adults may occur. Further studies to evaluate the relationship between HBV vaccination and sexual transmission are required for the young population in Korea.

한국인의 연, 망간, 알루미늄 및 실리콘의 혈중 농도

김정만,안정모,김원술,김정일,신해림,정갑열,김준연,Kim, Jung-Man,Ahn, Jung-Mo,Kim, Won-Sul,Kim, Jung-Il,Shin, Hai-Rim,Jung, Kap-Yeol,Kim, Joon-Youn 대한예방의학회 2000 Journal of Preventive Medicine and Public Health Vol.33 No.2

연, 망간, 알루미늄 및 실리콘에 대하여 직업적 노출이 없는 성인 132명(남성 67명, 여성 65명)을 대상으로 혈중 농도를 정량분석하여 다음과 같은 결과를 얻었다. 평균 혈중 연량(기하평근, 기하표준편차)은 남자군 (3.49, 1.70) ${\mu}g/dL$와 여자군 (3.04, 1.65) ${\mu}g/dL$로서 남자군에서 높았으나 유의한 차이는 없었고, 연령군별로는 남, 여 모두 차이가 없었다. 평균 혈중 망간량은 $0.99{\pm}0.41\;{\mu}g/dL$이었으며, 성별, 연령군별 유의한 차이는 관찰되지 않았다. 평균 혈중 알루미늄량은 $0.59{\pm}0.35\;{\mu}g/dL$이었으며, 성별, 연령군별 유의한 차이는 관찰되지 않았다. 평균 혈중 실리콘량은 남자군 $54.11{\pm}27.64\;{\mu}g/dL$, 여자군 $43.34{\pm}23.51\;{\mu}g/dL$로서 남자군에서 유의하게 높았고(p<0.05), 남자군의 경우 연령이 증가함에 따라 유의한 증가가 관찰되었으나(p<0.05), 여자군의 경우에는 연령군별로 차이가 없었다. 본 연구는 몇 가지 금속의 참고치 설정을 위한 기초 연구의 일환으로 앞으로의 연구에 자료로서 활용함으로써 이들 물질에 의한 인체장해의 평가와 예방관리에 일조 할 수 있을 것으로 생각된다. Objectives : This study was peformed to determine the reference values of blood lead, manganese, aluminium, and silicon in healthy adults. Methods : The subjects were 132 (67 male and 65 female), and classified to three age groups $(\leq39,\;40\sim49,\;and\;50\leq)$. Blood lead, manganese and aluminium were analyzed by atomic absorption spectrophotometer, and blood silicon was analyzed by direct current plasma optical emission spectrometer. Results : Blood lead levels(geometric mean, S.D) were (3.49, 1.70) ${\mu}g/dL$ in male and (3.04, 1.65) ${\mu}g/dL$ in female, but the difference is not significant, and there was no significant difference between age groups. Mean blood manganese level was $0.99{\pm}0.41{\mu}g/dL$, and there was no significant difference between sex or age groups. Mean blood aluminium level was $0.59{\pm}0.35{\mu}g/dL$, and there was no significant difference between sex or age groups. Mean blood silicon level was $54.41{\pm}27.64{\mu}g/dL$ in male and $43.34{\pm}23.51{\mu}g/dL$ in female, and the level in male was significantly higher than that in female (p<0.05). There was significant difference between age groups, and the oldest showed the highest level in male (p<0.05), but no significant difference between age groups in female. Conclusions : Authors hope that this study would provide basic data for determining reference values and evaluating health effects.